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公开(公告)号:US20180029032A1
公开(公告)日:2018-02-01
申请号:US15547751
申请日:2015-01-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Alexander Govyadinov , Erik D Torniainen , Pavel Kornilovich
IPC: B01L3/00
Abstract: A device for microfluidic transport includes a first fluid reservoir, a second fluid reservoir spaced from the first fluid reservoir, a main fluid channel communicated with the first fluid reservoir and the second fluid reservoir, an auxiliary fluid channel communicated with the main fluid channel, and a fluid actuator within the auxiliary fluid channel asymmetric to the main fluid channel such that operation of the fluidic actuator is to induce fluid flow in the main fluid channel from the first reservoir toward the second reservoir.
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公开(公告)号:US20170276259A1
公开(公告)日:2017-09-28
申请号:US15503664
申请日:2014-08-15
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Alexander Govyadinov , Erik D Torniainen , David P Markel , Pavel Kornilovich
CPC classification number: F16K99/0021 , B01L3/50273 , B01L3/502738 , B01L2300/023 , B01L2300/0864 , B01L2400/0442 , B01L2400/0622 , F04B53/10 , F04F7/00 , F16K99/0042 , F16K99/0055 , F16K2099/0084
Abstract: In an example implementation, a method of controlling a microfluidic valve includes activating a first inertial pump at a first frequency, and a second inertial pump at a second frequency to create a first fluid flow pattern within a microfluidic valve. The method also includes adjusting at least one of the first frequency and the second frequency to change the first fluid flow pattern to a second fluid flow pattern.
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公开(公告)号:US09409170B2
公开(公告)日:2016-08-09
申请号:US13925309
申请日:2013-06-24
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander Govyadinov , Pavel Kornilovich , Erik D. Torniainen , David P. Markel
IPC: F15D1/00 , F15D1/02 , B01L3/00 , B01F13/00 , B01F5/02 , B01F5/10 , B01F5/00 , F01D1/00 , F01D3/00
CPC classification number: B01L3/502715 , B01F5/0275 , B01F5/10 , B01F13/0059 , B01L3/50273 , B01L3/502738 , B01L3/502769 , B01L2200/0636 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/088 , B01L2400/0406 , B01L2400/0415 , B01L2400/043 , B01L2400/0433 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0633 , F01D1/00 , F01D3/00
Abstract: A microfluidic mixing device comprises a main channel and a number of secondary channels extending from a portion of the main channel and entering another portion of the main channel. A number of actuators are located in the secondary channels to pump fluids through the secondary channels. A microfluidic mixing system comprises a microfluidic mixing device. The microfluidic mixing device comprises a main fluid mixing channel, a number of main channel actuators to pump fluid through the main fluid mixing channel, a number of secondary channels fluidly coupled to the main fluid mixing channel, and a number of secondary channel actuators to pump fluids through the secondary channels. The microfluidic mixing device also comprises a fluid source, and a control device to provide fluids from the fluid source to the microfluidic mixing device and activate the main channel actuators and secondary channel actuators.
Abstract translation: 微流体混合装置包括主通道和从主通道的一部分延伸并进入主通道的另一部分的多个次通道。 多个致动器位于次级通道中以将流体泵送通过次级通道。 微流体混合系统包括微流体混合装置。 微流体混合装置包括主流体混合通道,多个主通道致动器以泵送通过主流体混合通道的流体,流体耦合到主流体混合通道的多个次通道,以及多个辅助通道致动器以泵送 流体通过次级通道。 微流体混合装置还包括流体源和控制装置,以将流体从流体源提供给微流体混合装置并且激活主通道致动器和次通道致动器。
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公开(公告)号:US20140377145A1
公开(公告)日:2014-12-25
申请号:US13925309
申请日:2013-06-24
Applicant: HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P.
Inventor: Alexander Govyadinov , Pavel Kornilovich , Erik D. Torniainen , David P. Markel
IPC: B01L3/00
CPC classification number: B01L3/502715 , B01F5/0275 , B01F5/10 , B01F13/0059 , B01L3/50273 , B01L3/502738 , B01L3/502769 , B01L2200/0636 , B01L2300/0816 , B01L2300/0861 , B01L2300/0867 , B01L2300/088 , B01L2400/0406 , B01L2400/0415 , B01L2400/043 , B01L2400/0433 , B01L2400/0439 , B01L2400/0442 , B01L2400/0478 , B01L2400/0633 , F01D1/00 , F01D3/00
Abstract: A microfluidic mixing device comprises a main channel and a number of secondary channels extending from a portion of the main channel and entering another portion of the main channel. A number of actuators are located in the secondary channels to pump fluids through the secondary channels. A microfluidic mixing system comprises a microfluidic mixing device. The microfluidic mixing device comprises a main fluid mixing channel, a number of main channel actuators to pump fluid through the main fluid mixing channel, a number of secondary channels fluidly coupled to the main fluid mixing channel, and a number of secondary channel actuators to pump fluids through the secondary channels. The microfluidic mixing device also comprises a fluid source, and a control device to provide fluids from the fluid source to the microfluidic mixing device and activate the main channel actuators and secondary channel actuators.
Abstract translation: 微流体混合装置包括主通道和从主通道的一部分延伸并进入主通道的另一部分的多个次通道。 多个致动器位于次级通道中以将流体泵送通过次级通道。 微流体混合系统包括微流体混合装置。 微流体混合装置包括主流体混合通道,多个主通道致动器以泵送通过主流体混合通道的流体,流体耦合到主流体混合通道的多个次通道,以及多个辅助通道致动器以泵送 流体通过次级通道。 微流体混合装置还包括流体源和控制装置,以将流体从流体源提供给微流体混合装置并且激活主通道致动器和次通道致动器。
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公开(公告)号:US12186748B2
公开(公告)日:2025-01-07
申请号:US17848864
申请日:2022-06-24
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Peiyun Wang , Pavel Kornilovich , Alexander Govyadinov , Noorashekin Binte Jamil , Sarita Jairam , Jinghua Zhao
Abstract: An example self-priming microfluidic structure can include a microfluidic channel including a floor and a ceiling. A channel height is defined as a distance between the floor and the ceiling. A channel height step can be in the floor, or ceiling, or both. The channel height downstream of the channel height step can be greater than the channel height upstream of the channel height step. An interior pillar can be positioned in the microfluidic channel extending from the floor to the ceiling. The interior pillar can include a widening portion at an upstream end of the interior pillar and a tapering portion at a downstream end of the interior pillar. The interior pillar can overlap the channel height step so that the interior pillar is partially upstream of the channel height step and partially downstream of the channel height step.
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公开(公告)号:US20240299942A1
公开(公告)日:2024-09-12
申请号:US18573690
申请日:2021-06-30
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson Denison , Pavel Kornilovich , Alexander Govyadinov , Erik D. Torniainen , Richard W. Seaver , Anand Samuel Jebakumar
IPC: B01L3/00
CPC classification number: B01L3/502746 , B01L2300/0816 , B01L2300/087 , B01L2300/0874 , B01L2400/086
Abstract: A microfluidic device includes a chamber having a floor, a ceiling, and an inlet. The microfluidic device includes pillars extending from the floor to the ceiling of the chamber. Each pillar has a leading surface or corner, a trailing surface or corner opposite the leading surface or corner, and trailing side surfaces adjoining the trailing surface or corner. Each pillar is oriented along a corresponding ray intersecting the leading surface or corner and the trailing surface or corner. Adjacent pillars have a turn angle between the corresponding rays of the adjacent pillars, and each pillar has a pillar angle between the trailing side surfaces thereof. The turn and pillar angles are based on a fluidic contact angle to promote fluid flow from the inlet throughout the chamber during priming without fluidic pinning.
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公开(公告)号:US20240246084A1
公开(公告)日:2024-07-25
申请号:US18559761
申请日:2021-05-10
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Carson Denison , Alexander Govyadinov , Richard W. Seaver , Erik D. Torniainen , Pavel Kornilovich , Anand Samuel Jebakumar
IPC: B01L7/00
CPC classification number: B01L7/52 , B01L2300/1805 , B01L2300/1894
Abstract: Apparatuses may be used for nucleic acid amplification. An example apparatus may include an amplification chamber to contain a biochemical reaction associated with amplification of a biologic sample. The biologic sample may include a nucleic acid. The apparatus may also include a heater thermally coupled to the amplification chamber. The apparatus may also include a thermally conductive substrate in contact with the heater and including a liquid coolant passage to pass a liquid coolant through the thermally conductive substrate.
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公开(公告)号:US11988594B2
公开(公告)日:2024-05-21
申请号:US18196947
申请日:2023-05-12
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Alexander Govyadinov , Pavel Kornilovich
CPC classification number: G01N15/1484 , B01L3/50273 , H10N30/2047 , G01N2015/1006 , G01N2015/1028
Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a sensor to categorize particles in the input channel into one of at least two categories, and at least two output channels. Each output channel is coupled to the second end of the input channel to receive particles from the input channel, and each output channel is associated with at least one category of the at least two categories. Each output channel has a corresponding pump operable, based on the categorization of a detected particle in a category associated with a different output channel, to selectively slow, stop, or reverse a flow of particles into the output channel from the input channel.
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公开(公告)号:US20230280263A1
公开(公告)日:2023-09-07
申请号:US18196947
申请日:2023-05-12
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Alexander Govyadinov , Pavel Kornilovich
CPC classification number: G01N15/1484 , B01L3/50273 , H10N30/2047 , G01N2015/1006
Abstract: An example system includes an input channel having a first end and a second end to receive particles through the first end, a sensor to categorize particles in the input channel into one of at least two categories, and at least two output channels. Each output channel is coupled to the second end of the input channel to receive particles from the input channel, and each output channel is associated with at least one category of the at least two categories. Each output channel has a corresponding pump operable, based on the categorization of a detected particle in a category associated with a different output channel, to selectively slow, stop, or reverse a flow of particles into the output channel from the input channel.
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公开(公告)号:US11698149B2
公开(公告)日:2023-07-11
申请号:US16477807
申请日:2017-02-15
Applicant: Hewlett-Packard Development Company, L.P.
Inventor: Pavel Kornilovich , Alexander N. Govyadinov , Viktor Shkolnikov
CPC classification number: F16K99/0017 , B01L3/502738 , B01L3/502784 , B01L2300/06 , B01L2300/0627 , B01L2300/1827 , B01L2400/0688
Abstract: A microfluidic valve may include a first portion of a liquid conduit to contain a gas, a second portion of a liquid conduit to contain a liquid, and a constriction between the first portion and the second portion and across which a capillary meniscus is to form between the gas and the liquid. The microfluidic valve may further include a drop jetting device within the second portion to open the valve by breaking the capillary meniscus across the constriction.
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