公开(公告)号：US07619374B2

公开(公告)日：2009-11-17

申请号：US11987808

申请日：2007-12-04

申请人： Tatsufumi Aoi ,  Kuniyuki Kajinishi ,  Ichiro Yamashita ,  Shinji Nomura ,  Yoshio Sugimoto ,  Susumu Urano

发明人： Tatsufumi Aoi ,  Kuniyuki Kajinishi ,  Ichiro Yamashita ,  Shinji Nomura ,  Yoshio Sugimoto ,  Susumu Urano

IPC分类号： H01J23/00

CPC分类号： H05H7/02 ,  A61N5/10 ,  H05H9/00 ,  H05H15/00

摘要： A radiotherapy system includes: a waveguide, an adjustable waveguide, and a non-reciprocal circuit element. The waveguide transmits a high-frequency wave from a high-frequency power source to an acceleration tube. The adjustable waveguide is included in said waveguide and transforms a part of said waveguide. The non-reciprocal circuit element is provided between said acceleration tube and said adjustable waveguide in said waveguide. Said acceleration tube accelerates charged particles for generating therapeutic radiation by using said high-frequency wave.

摘要翻译： 放射治疗系统包括：波导，可调节波导和不可逆电路元件。 波导将高频波从高频电源传输到加速管。 可调波导包括在所述波导中并且转换所述波导的一部分。 不可逆电路元件设置在所述波导管内的所述加速管与所述可调波导之间。 所述加速管通过使用所述高频波加速用于产生治疗辐射的带电粒子。

公开(公告)号：US20090187010A1

公开(公告)日：2009-07-23

申请号：US12320556

申请日：2009-01-29

申请人： Shigeo Yoshii ,  Kazuaki Nishio ,  Shinya Kumagai ,  Ichiro Yamashita

发明人： Shigeo Yoshii ,  Kazuaki Nishio ,  Shinya Kumagai ,  Ichiro Yamashita

IPC分类号： C07K17/00

CPC分类号： C07K14/47 ,  B82B1/00 ,  B82Y30/00

摘要： To provide a method of arranging ferritin by which a high rate of the number of the molecular film spots on which sole ferritin molecule was arranged in effect, with respect to total number of the molecular film spots provided for arranging ferritin (sole arrangement rate) is achieved is objected to. Specifically, in Fer8 ferritin having a sequence excluding 7 amino acids of from the second to the eighth, from an amino acid sequence (Fer0 sequence) translated from a naturally occurring DNA sequence, lysine at position 91 is substituted with glutamic acid.

摘要翻译： 为了提供一种安排铁蛋白的方法，相对于提供用于安排铁蛋白的总分子膜点数（单独排列速率），通过该铁蛋白排列高分子膜斑点的数量，单个铁蛋白分子排列有效的方法是： 实现是反对的。 具体而言，在来自第二至第八的7个氨基酸序列的Fer8铁蛋白中，从天然存在的DNA序列翻译的氨基酸序列（Fer0序列）中，91位的赖氨酸被谷氨酸取代。

公开(公告)号：US07439334B2

公开(公告)日：2008-10-21

申请号：US11354864

申请日：2006-02-16

申请人： Ichiro Yamashita ,  Kiyotaka Shiba

发明人： Ichiro Yamashita ,  Kiyotaka Shiba

IPC分类号： C07K14/00 ,  H01L21/00 ,  H01L21/314 ,  H01L21/471

CPC分类号： C07K14/47 ,  C07K2319/00 ,  G01N33/553

摘要： A method for selectively arranging ferritin modified with a peptide, which specifically binds to titanium, to titanium formed on a substrate surface is provided.The method for arranging ferritin of the present invention is characterized in that ferritin is selectively bound on titanium on a substrate by modifying the N-terminal part of ferritin with a peptide which specifically binds to titanium. Also, the method for arranging ferritin of the present invention is characterized in that selectivity for titanium can be markedly improved by adding a nonionic surface activating agent.

摘要翻译： 提供了一种选择性地将由钛特异性结合的肽修饰的铁蛋白修饰成在基底表面上形成的钛的方法。 本发明的铁蛋白的配置方法的特征在于，通过用特异性结合钛的肽修饰铁蛋白的N末端部分，将铁蛋白选择性地结合在底物上的钛上。 此外，本发明的铁蛋白的配置方法的特征在于，通过添加非离子表面活性剂，能够显着提高钛的选择性。

公开(公告)号：US07419529B2

公开(公告)日：2008-09-02

申请号：US11284910

申请日：2005-11-23

申请人： Shigeo Yoshii ,  Michihito Ueda ,  Nozomu Matsukawa ,  Ichiro Yamashita

发明人： Shigeo Yoshii ,  Michihito Ueda ,  Nozomu Matsukawa ,  Ichiro Yamashita

IPC分类号： B22F9/20

CPC分类号： B82Y10/00 ,  H01L21/28273 ,  H01L21/28282 ,  H01L29/42332

摘要： An object of the present invention is to provide a method of forming fine particles on a substrate in which reoxidization of reduced fine particles is suppressed. Reduced fine particles (FeO fine particles) are formed by embedding metal oxide fine particles (Fe2O3 fine particles) fixed on a p type silicon semiconductor substrate into a silicon oxidized film, and carrying out a heat treatment in a reducing gas atmosphere. Presence of the silicon oxidized film enables suppression of reoxidization of the reduced fine particles (FeO fine particles) due to exposure to the ambient air.

摘要翻译： 本发明的目的是提供一种在抑制还原的微粒的再氧化的基板上形成微粒的方法。 通过将固定在p型硅半导体衬底上的金属氧化物微粒（Fe 2 O 3 O 3微粒）嵌入到硅氧化膜中而形成还原的微粒（FeO微粒） ，并在还原气体气氛中进行热处理。 硅氧化膜的存在能够抑制由于暴露于环境空气而导致的还原的微粒（FeO微粒）的再氧化。

公开(公告)号：US20080154024A1

公开(公告)日：2008-06-26

申请号：US11385006

申请日：2006-03-21

申请人： Hiroya Kirimura ,  Ichiro Yamashita

发明人： Hiroya Kirimura ,  Ichiro Yamashita

IPC分类号： C07K14/79

CPC分类号： C07K14/47 ,  C07K2319/00

摘要： A method for selectively arranging ferritin in a specified inorganic material part formed on a substrate is provided. The method for arranging ferritin of the present invention is characterized in that ferritin is selectively arranged on a part including titanium or silicon nitride (SiN) in an efficient manner by adding a nonionic surface active agent. Also, selective arrangement capability of ferritin can be markedly improved by modifying the N-terminus of ferritin with a certain peptide.

摘要翻译： 提供了一种在基板上形成的规定的无机材料部分中选择性地配置铁蛋白的方法。 本发明的铁蛋白的配置方法的特征在于，通过添加非离子表面活性剂，有效地将铁蛋白选择性地配置在包含钛或氮化硅（SiN）的部分上。 此外，通过用某种肽修饰铁蛋白的N末端，可以显着改善铁蛋白的选择性排列能力。

公开(公告)号：US07015139B2

公开(公告)日：2006-03-21

申请号：US10456496

申请日：2003-06-09

申请人： Ichiro Yamashita

发明人： Ichiro Yamashita

IPC分类号： H01L21/44

CPC分类号： H01L49/006 ,  B05D1/202 ,  B82Y10/00 ,  B82Y30/00 ,  B82Y40/00 ,  G11C2216/08 ,  H01L21/2254 ,  H01L21/3081 ,  H01L21/3086 ,  H01L21/76838 ,  H01L21/8222 ,  H01L27/156 ,  H01L29/66136 ,  H01L29/7613 ,  H01L33/06 ,  H01L33/18 ,  H01L2924/0002 ,  Y10S438/939 ,  Y10S438/945 ,  Y10S438/947 ,  Y10S438/962 ,  H01L2924/00

摘要： A quantum device is constituted from a two-dimensional array of quantum dots formed from metal atom aggregates contained in a metalloprotein complex. The metalloprotein is arranged on the surface of a substrate having an insulation layer with a pitch of the size of the metalloprotein complex. The diameter of the metal atom aggregates used in the quantum device is 7 nm or smaller, and the pitch of the metalloprotein complex is preferably from 11 to 14 nm.

公开(公告)号：US20060024790A1

公开(公告)日：2006-02-02

申请号：US11229240

申请日：2005-09-16

申请人： Ichiro Yamashita

发明人： Ichiro Yamashita

IPC分类号： C07H21/04 ,  C12P21/06 ,  C07K14/79

CPC分类号： H01L29/42332 ,  A61K38/00 ,  C07K14/47 ,  Y10T428/12868 ,  Y10T428/253

摘要： Using a gene recombination technique, a glutamic acid and an aspartic acid positioned in a channel of apoferritin are substituted with serine having a small size and no charges. Then, a glutamic acid positioned in a holding portion is substituted with a basic amino acid such as lysine or a neutral amino acid. Furthermore, at least one cysteine is introduced into the holding portion. This prevents a repulsive force due to electrostatic interaction between (AuCl4)− having a negative charge and a negative amino acid from occurring, which facilitates the capture of (AuCl4)− into the channel and the holding portion. The (AuCl4)− captured into the holding portion is subsequently reduced to Au, and thus apoferritin including gold particles can be produced.

公开(公告)号：US06891309B2

公开(公告)日：2005-05-10

申请号：US10445610

申请日：2003-05-27

申请人： Noboru Nomura ,  Ichiro Yamashita ,  Norihisa Mino ,  Tohru Nakagawa

发明人： Noboru Nomura ,  Ichiro Yamashita ,  Norihisa Mino ,  Tohru Nakagawa

IPC分类号： H02N1/00

CPC分类号： H02N1/004 ,  Y10T29/49226

摘要： A novel structure comprising two substrates disposed closely each other, in which an organic molecular layer is formed on the surface of at least one substrate wherein the gap between the surface of the organic molecular layer on one substrate and the surface of the other substrate or the surface of the organic molecular layer on the other substrate is maintained to be usually less than 100 μm, preferably less than 1 μm is provided. A motor, actuator, and vibration-absorbing table comprising such structure are also provided.

摘要翻译： 一种新颖的结构，包括彼此紧密相邻的两个基板，其中在至少一个基板的表面上形成有机分子层，其中一个基板上的有机分子层的表面与另一个基板的表面之间的间隙或 将另一基板上的有机分子层的表面保持通常小于100μm，优选小于1μm。 还提供了包括这种结构的电动机，致动器和减振台。

公开(公告)号：US06759568B2

公开(公告)日：2004-07-06

申请号：US09893666

申请日：2001-06-29

申请人： Ichiro Yamashita

发明人： Ichiro Yamashita

IPC分类号： G01N3300

CPC分类号： C12N15/8509 ,  A01K67/0275 ,  A01K2217/05 ,  A01K2227/40 ,  A01K2267/03 ,  C07K14/461 ,  G01N33/186 ,  G01N33/5082 ,  G01N33/74 ,  G01N2520/00

摘要： (1) Transgenic medaka fish into which a polynucleotide having the nucleotide sequence from 211 to 1935 position represented by Sequence ID No: 1 is introduced, (2) A method of producing medaka fish having one or more thrombi, comprising the step of raising the transgenic medaka fish described in (1) in the presence of estrogen, (3) Medaka fish having one or more thrombi produced by the method described in (2), and (4) A method of testing an estrogen-like acting substance, comprising the steps of raising the transgenic medaka fish described in (1) in test water, and observing whether or not one or more thrombi are formed in the medaka fish after the raising step.

摘要翻译： （1）引入具有由序列号1表示的211〜1935位置的碱基序列的多核苷酸的转基因aka鱼，（2）一种制备具有一个或多个血栓的aka鱼的方法，其包括： （1）中描述的在雌激素存在下的转基因aka鱼，（3）通过（2）中描述的方法制备的具有一种或多种血栓的楝树鱼，和（4）一种测试雌激素样作用物质的方法，包括 （1）中描述的转基因aka鱼在试验水中的步骤，并且观察在升高步骤之后是否在aka鱼中形成一个或多个血栓。

公开(公告)号：US06303516B1

公开(公告)日：2001-10-16

申请号：US09208753

申请日：1998-12-10

申请人： Kiyoyuki Morita ,  Kiyoshi Morimoto ,  Kiyoshi Araki ,  Koichiro Yuki ,  Kazuyasu Adachi ,  Masayuki Endo ,  Ichiro Yamashita

发明人： Kiyoyuki Morita ,  Kiyoshi Morimoto ,  Kiyoshi Araki ,  Koichiro Yuki ,  Kazuyasu Adachi ,  Masayuki Endo ,  Ichiro Yamashita

IPC分类号： H01L2146

CPC分类号： G11C13/0014 ,  B82Y10/00 ,  G11C11/5664 ,  G11C11/5671 ,  G11C13/0019 ,  G11C2216/08 ,  H01L21/28273 ,  H01L21/288 ,  H01L21/768 ,  H01L29/7883 ,  Y10S438/962

摘要： A Rat IgG antibody film, formed on a p-type Si substrate, is selectively irradiated with ultraviolet rays, thereby leaving part of the Rat IgG antibody film, except for a region deactivated with the ultraviolet rays. Next, when the p-type Si substrate is immersed in a solution containing Au fine particles that have been combined with a Rat IgG antigen, the Rat IgG antigen is selectively combined with the Rat IgG antibody film. As a result, Au fine particles, combined with the Rat IgG antigen, are fixed on the Rat IgG antibody film. Thereafter, the p-type Si substrate is placed within oxygen plasma for 20 minutes, thereby removing the Rat IgG antibody film, the deactivated Rat IgG antibody film and the Rat IgG antigen. Consequently, dot elements can be formed at desired positions on the p-type Si substrate. If these dot elements are used for the floating gate of a semiconductor memory device, then the device has a structure suitable for miniaturization.

摘要翻译： 在p型Si衬底上形成的大鼠IgG抗体膜被紫外线选择性照射，除了用紫外线去活化的区域外，还剩下部分IgG抗体。 接下来，当将p型Si衬底浸入含有与大鼠IgG抗原组合的Au微粒的溶液中时，将大鼠IgG抗原与大鼠IgG抗体膜选择性组合。 结果，将Au细粒与大鼠IgG抗原组合，固定在大鼠IgG抗体膜上。 此后，将p型Si衬底置于氧等离子体中20分钟，从而除去大鼠IgG抗体膜，失活的大鼠IgG抗体膜和大鼠IgG抗原。 因此，可以在p型Si衬底上的期望位置形成点元件。 如果这些点元件用于半导体存储器件的浮动栅极，则该器件具有适于小型化的结构。