公开(公告)号：US07807176B2

公开(公告)日：2010-10-05

申请号：US10593518

申请日：2005-03-17

申请人： Tomoyuki Nishikawa ,  Hironori Nakagami ,  Yasufumi Kaneda

发明人： Tomoyuki Nishikawa ,  Hironori Nakagami ,  Yasufumi Kaneda

IPC分类号： A61K39/00 ,  C07H21/04

CPC分类号： C12N15/86 ,  A61K31/7088 ,  A61K38/00 ,  A61K48/00 ,  C07K14/515 ,  C07K14/52 ,  C12N2760/18643 ,  C12N2760/18671

摘要： It is intended to provide a novel polypeptide having an activity of growing vascular endothelial cells, an activity of promoting transcription form c-fos promoter, an activity of promoting transciption from VEGF promoter and/or an angiogenic activity; a polynucleotide encoding this polypeptide; the above polypeptide and/or a pharmaceutical composition containing the polypeptide for treating a disease selected from the group consisting of obstructive arteriosclerosis, Buerger's disease, peripheral vascular disorder, angina, myocardial infraction, brain infarction, ischemic heart disease and ischemic brain disease; a method of treating these diseases; and an antibacterial composition. The above problems can be solved by isolating a novel peptide having the above-described activities and a nucleotide encoding this peptide.

摘要翻译： 旨在提供具有生长血管内皮细胞活性的新型多肽，促进c-fos启动子转录的活性，促进VEGF启动子的转录活性和/或血管生成活性的活性; 编码该多肽的多核苷酸; 上述多肽和/或含有治疗选自以下的疾病多肽的药物组合物：阻塞性动脉硬化，Buerger氏病，外周血管病症，心绞痛，心肌梗死，脑梗塞，缺血性心脏病和缺血性脑病; 治疗这些疾病的方法; 和抗菌组合物。 通过分离具有上述活性的新肽和编码该肽的核苷酸可以解决上述问题。

公开(公告)号：US07795999B2

公开(公告)日：2010-09-14

申请号：US11878747

申请日：2007-07-26

申请人： Yasufumi Kaneda ,  Osamu Kawachi ,  Seiichi Mitobe ,  Kouta Ookubo

发明人： Yasufumi Kaneda ,  Osamu Kawachi ,  Seiichi Mitobe ,  Kouta Ookubo

IPC分类号： H03H9/64

CPC分类号： H03H9/6476 ,  H03H9/14582

摘要： A filter includes a first filter that is connected between an input node and an output node and is a surface acoustic wave filter, and a second filter that is provided between the input node and the output node and is connected in parallel with the first filter. The first filter has a total number N1 of pairs of electrode fingers of interdigital transducers and the second filter having a total number N2 of pairs of electrode fingers of interdigital transducers, in which N1 is greater than N2.

摘要翻译： 滤波器包括连接在输入节点和输出节点之间并且是表面声波滤波器的第一滤波器，以及设置在输入节点和输出节点之间并与第一滤波器并联连接的第二滤波器。 第一滤波器具有交叉指型换能器的电极指数对N1的总数，并且第二滤波器具有跨数字换能器的电极指对的总数N2，其中N1大于N2。

公开(公告)号：US20090212399A1

公开(公告)日：2009-08-27

申请号：US12388215

申请日：2009-02-18

申请人： Yasufumi Kaneda ,  Akira Moriya ,  Kaoru Sakinada ,  Shunichi Aikawa ,  Yoshinori Kondou ,  Takashi Yamashita

发明人： Yasufumi Kaneda ,  Akira Moriya ,  Kaoru Sakinada ,  Shunichi Aikawa ,  Yoshinori Kondou ,  Takashi Yamashita

IPC分类号： H01L23/538 ,  H01L21/70

CPC分类号： H03H9/059 ,  H01L2924/0002 ,  H03H3/08 ,  H03H9/1092 ,  H01L2924/00

摘要： An electronic component includes a substrate, a functional element formed on the substrate, a plurality of terminals including a first terminal electrode connected to the functional element and a second terminal electrode layered on the first terminal electrode, and a feed line, one end of which is electrically connected to the first terminal electrode and the other end of which reaches an edge of the substrate, wherein the feed line includes a first portion directly reaching the edge, and a second portion branching from the first portion and then reaching the edge.

摘要翻译： 电子部件包括基板，形成在基板上的功能元件，多个端子，包括连接到功能元件的第一端子电极和层叠在第一端子电极上的第二端子电极，以及馈电线路，其一端 电连接到第一端子电极并且其另一端到达基板的边缘，其中馈电线包括直接到达边缘的第一部分和从第一部分分支然后到达边缘的第二部分。

公开(公告)号：US20080312130A1

公开(公告)日：2008-12-18

申请号：US12054200

申请日：2008-03-24

申请人： Yasufumi Kaneda ,  Chun-Man Lee ,  Yasuhiko Tabata ,  Tomoyuki Asano

发明人： Yasufumi Kaneda ,  Chun-Man Lee ,  Yasuhiko Tabata ,  Tomoyuki Asano

IPC分类号： A61K48/00 ,  A61K38/02 ,  A61K31/7088 ,  A61K31/69 ,  A61P35/00 ,  A61K47/42

CPC分类号： A61K31/69 ,  A61K31/7088 ,  A61K47/60 ,  A61K47/61 ,  A61K48/0008 ,  C12N7/00 ,  C12N2760/18842 ,  C12N2760/18851 ,  C12N2760/18862 ,  C12N2760/18863

摘要： The invention provides a vehicle that can deliver drugs specifically to the body and a pharmaceutical preparation using the same. Disclosed is a drug delivery vehicle for cancer therapy, comprising a cationized viral envelope vector, as well as a pharmaceutical preparation comprising a drug enclosed in the vehicle. The viral envelope vector is for example HVJ-E derived from a Sendai virus, and cationization can be conducted by binding hyaluronic acid-introduced cationized gelatin or ethylene glycol-introduced cationized gelatin with the viral envelope vector. The drug to be enclosed is a nucleic acid, a vector containing a nucleic acid sequence, a protein based drug or pharmaceutical with a low-molecular compound.

摘要翻译： 本发明提供了能够将药物特异性地递送到身体的载体和使用其的药物制剂。 公开了一种用于癌症治疗的药物递送载体，其包含阳离子化病毒包膜载体，以及包含在载体中的药物的药物制剂。 病毒包膜载体是例如源自仙台病毒的HVJ-E，并且阳离子化可以通过将透明质酸引入的阳离子明胶或乙二醇引入的阳离子化明胶与病毒包膜载体结合来进行。 待封装的药物是核酸，含有核酸序列，基于蛋白质的药物或具有低分子化合物的药物的载体。

公开(公告)号：US20080111247A1

公开(公告)日：2008-05-15

申请号：US11598816

申请日：2006-11-14

申请人： Kaoru Sakinada ,  Takumi Kooriike ,  Shunichi Aikawa ,  Osamu Kawachi ,  Yasufumi Kaneda

发明人： Kaoru Sakinada ,  Takumi Kooriike ,  Shunichi Aikawa ,  Osamu Kawachi ,  Yasufumi Kaneda

IPC分类号： H01L23/488 ,  B23K31/02 ,  H01L21/60

CPC分类号： B23K1/0016 ,  H01L23/10 ,  H01L24/97 ,  H01L2224/0554 ,  H01L2224/05568 ,  H01L2224/05573 ,  H01L2224/16225 ,  H01L2224/73253 ,  H01L2224/97 ,  H01L2924/00014 ,  H01L2924/01079 ,  H03H9/059 ,  H03H9/1078 ,  H03H9/1085 ,  H01L2224/81 ,  H01L2224/05599 ,  H01L2224/0555 ,  H01L2224/0556

摘要： There is provided a method of fabricating an electronic device including flip-chip mounting a device chip on a substrate, and supplying solder between adjacent device chips by supplying the solder on the device chips and applying heat and pressure on the solder, and a contact angle of the device chip and the solder is greater than 90° with the solder melted.

摘要翻译： 提供了一种制造电子器件的方法，该电子器件包括将器件芯片安装在衬底上的倒装芯片，以及通过在器件芯片上提供焊料并在焊料上施加热和压力来在相邻器件芯片之间提供焊料，以及接触角 的焊料熔化时，器件芯片和焊料大于90°。

公开(公告)号：US20050242903A1

公开(公告)日：2005-11-03

申请号：US11114128

申请日：2005-04-26

申请人： Shogo Inoue ,  Motoyuki Tajima ,  Takayuki Yamaji ,  Yasufumi Kaneda ,  Osamu Kawachi ,  Masanori Ueda

发明人： Shogo Inoue ,  Motoyuki Tajima ,  Takayuki Yamaji ,  Yasufumi Kaneda ,  Osamu Kawachi ,  Masanori Ueda

IPC分类号： H03H9/25 ,  H03H9/00 ,  H03H9/05 ,  H03H9/64

CPC分类号： H03H9/059 ,  H03H9/0071 ,  H03H9/0095

摘要： A balanced filter includes a package having an input ground metal pattern and an output ground metal pattern, and a filter chip having an inphase filter and an antiphase filter, which filters are mounted on the package, at least one of the inphase and antiphase filters having an input ground terminal connected to the input ground metal pattern and an output ground terminal connected to the output ground metal pattern, the input and output ground terminals of said at least one of the inphase and antiphase filters being separate from each other on the filter chip.

摘要翻译： 平衡滤波器包括具有输入接地金属图案和输出接地金属图案的封装以及具有同相滤波器和反相滤波器的滤波器芯片，该滤波器安装在封装上，至少一个同相滤波器和反相滤波器具有 连接到输入接地金属图案的输入接地端子和连接到输出接地金属图案的输出接地端子，所述至少一个同相和反相滤波器的输入和输出接地端子在滤波器芯片上彼此分离 。

公开(公告)号：US20050003790A1

公开(公告)日：2005-01-06

申请号：US10746255

申请日：2003-12-29

申请人： Osamu Kawachi ,  Takuya Abe ,  Yasufumi Kaneda ,  Motoyuki Tajima

发明人： Osamu Kawachi ,  Takuya Abe ,  Yasufumi Kaneda ,  Motoyuki Tajima

IPC分类号： H03H9/145 ,  H03H9/02 ,  H04B1/46 ,  H04B1/10 ,  H04B1/16 ,  H04B1/18

CPC分类号： H03H9/02771

摘要： A surface acoustic wave device for implementing an attenuation characteristic outside of the pass band and the narrow band characteristics, preferably for use as a filter. The surface acoustic wave device includes a piezoelectric substrate, interdigital transducers formed on the piezoelectric substrate, and first and second reflectors disposed on the sides of the interdigital transducers. Each of the first and second reflectors includes an open electrode block with a plurality of electrically independent electrode fingers, and a short electrode block with a plurality of electrode fingers of which both ends are electrically shorted.

摘要翻译： 用于实现通带外的衰减特性和窄带特性的表面声波装置，优选用作滤波器。 表面声波装置包括压电基板，形成在压电基板上的叉指换能器，以及设置在叉指式换能器侧面的第一和第二反射器。 第一和第二反射器中的每一个包括具有多个电独立电极指的开放电极块，以及具有多个电极指的短电极块，其两端电气短路。

公开(公告)号：US06432925B1

公开(公告)日：2002-08-13

申请号：US09061794

申请日：1998-04-16

申请人： Dave S. B. Hoon ,  Yasufumi Kaneda

发明人： Dave S. B. Hoon ,  Yasufumi Kaneda

IPC分类号： A61K4800

CPC分类号： A61K39/0011 ,  A61K9/1271 ,  A61K48/00

摘要： RNA cancer vaccines and methods for their use are described. The vaccines are comprised of viral liposomes comprising nucleic acid, preferably RNA, encoding a tumor-associated antigen. The viral liposomes may be formed by the fusion of HVJ reagents with nonviral reagents. The vaccine may be administered subcutaneously, intradermally, intramuscularly or into an organ. The vaccine may be administered to induce a host normal cell to express the tumor associated antigen.

摘要翻译： 描述RNA癌症疫苗及其使用方法。 疫苗由包含编码肿瘤相关抗原的核酸，优选RNA的病毒脂质体组成。 病毒脂质体可以通过HVJ试剂与非病毒试剂的融合形成。 疫苗可以皮下，皮内，肌肉内或器官内给药。 可以施用疫苗以诱导宿主正常细胞以表达肿瘤相关抗原。