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    Method of making a variable surface area stent
    63.
    发明授权
    Method of making a variable surface area stent 有权
    制造可变面积支架的方法

    公开(公告)号：US08119184B2

    公开(公告)日：2012-02-21

    申请号：US12688571

    申请日：2010-01-15

    Applicant: Syed Hossainy ,  Fuh-Wei Tang ,  Brian P. Cahill

    Inventor： Syed Hossainy ,  Fuh-Wei Tang ,  Brian P. Cahill

    IPC: A61L33/00 ,  B05D3/12 ,  B05D3/10

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0095 ,  A61F2230/0013 ,  A61F2250/0025 ,  A61F2250/0067 ,  A61F2250/0068

    Abstract: A stent of variable surface area as determined by stent struts. The stent can have a variable surface area per unit length which accommodates a therapeutic agent. A patterned distribution of therapeutic agent can be provided throughout the stent. The stent can have an increased level of therapeutic agent near an end of the stent. A decreased level of therapeutic agent can be provided near an end of one embodiment of a stent. Indentations can be provided at the surface of the stent with therapeutic agent disposed therein. The stent can be cut with struts of variable thickness to provide the variable stent surface area.

    Abstract translation: 由支架支柱确定的可变表面积的支架。 支架可以具有容纳治疗剂的每单位长度的可变表面积。 可以在整个支架中提供治疗剂的图案化分布。 支架可以在支架的端部附近具有增加的治疗剂水平。 在支架的一个实施方案的末端附近可以提供降低的治疗剂水平。 可以在支架的表面设置缺陷，其中设置有治疗剂。 可以用可变厚度的支柱切割支架，以提供可变的支架表面积。

    METHOD OF MAKING A VARIABLE SURFACE AREA STENT
    67.
    发明申请
    METHOD OF MAKING A VARIABLE SURFACE AREA STENT 有权
    制造可变表面区域的方法

    公开(公告)号：US20100116785A1

    公开(公告)日：2010-05-13

    申请号：US12688571

    申请日：2010-01-15

    Applicant: Syed Hossainy ,  Fuh-Wei Tang ,  Brian P. Cahill

    Inventor： Syed Hossainy ,  Fuh-Wei Tang ,  Brian P. Cahill

    IPC: B05D3/10 ,  C23F1/00

    CPC classification number: A61F2/91 ,  A61F2/915 ,  A61F2002/91533 ,  A61F2002/91575 ,  A61F2210/0095 ,  A61F2230/0013 ,  A61F2250/0025 ,  A61F2250/0067 ,  A61F2250/0068

    Abstract: A stent of variable surface area as determined by stent struts. The stent can have a variable surface area per unit length which accommodates a therapeutic agent. A patterned distribution of therapeutic agent can be provided throughout the stent. The stent can have an increased level of therapeutic agent near an end of the stent. A decreased level of therapeutic agent can be provided near an end of one embodiment of a stent. Indentations can be provided at the surface of the stent with therapeutic agent disposed therein. The stent can be cut with struts of variable thickness to provide the variable stent surface area.

    Abstract translation: 由支架支柱确定的可变表面积的支架。 支架可以具有容纳治疗剂的每单位长度的可变表面积。 可以在整个支架中提供治疗剂的图案化分布。 支架可以在支架的端部附近具有增加的治疗剂水平。 在支架的一个实施方案的末端附近可以提供降低的治疗剂水平。 可以在支架的表面设置缺陷，其中设置有治疗剂。 可以用可变厚度的支柱切割支架，以提供可变的支架表面积。

    System for Coating Stents
    68.
    发明申请
    System for Coating Stents 有权
    涂层支架系统

    公开(公告)号：US20080110396A1

    公开(公告)日：2008-05-15

    申请号：US12014017

    申请日：2008-01-14

    Applicant: Syed Hossainy

    Inventor： Syed Hossainy

    IPC: B05D1/32 ,  B05B7/06 ,  B05C13/02 ,  B05C11/11 ,  B05B15/04

    CPC classification number: B05D1/34 ,  B05B13/0228 ,  B05D1/002 ,  B05D1/02

    Abstract: A system for coating implantable medical devices, such as stents, and a method of coating stents using the system is also disclosed. The system includes a barrier or barriers for isolating an area of the stent on which a composition for coating a stent is applied. Two coating compositions can be applied simultaneously to a stent by separate nozzles on different sides of a barrier. Cross-contamination of the compositions is prevented by the barrier.

    Abstract translation: 还公开了一种用于涂覆诸如支架的可植入医疗装置的系统，以及使用该系统涂覆支架的方法。 该系统包括用于隔离其上应用用于涂覆支架的组合物的支架的区域的屏障或障碍物。 两个涂层组合物可以通过在屏障的不同侧面上的分开的喷嘴同时施用于支架。 通过屏障防止组合物的交叉污染。

    METHOD OF POLISHING IMPLANTABLE MEDICAL DEVICES TO LOWER THROMBOGENECITY AND INCREASE MECHANICAL STABILITY
    69.
    发明申请
    METHOD OF POLISHING IMPLANTABLE MEDICAL DEVICES TO LOWER THROMBOGENECITY AND INCREASE MECHANICAL STABILITY 有权
    抛光可植入医疗器械以降低血栓形成并增加机械稳定性的方法

    公开(公告)号：US20080099442A1

    公开(公告)日：2008-05-01

    申请号：US11969181

    申请日：2008-01-03

    Applicant: DAVID GALE ,  Syed Hossainy

    Inventor： DAVID GALE ,  Syed Hossainy

    IPC: B44C1/22

    CPC classification number: A61L31/10 ,  A61F2/91 ,  A61F2210/0004 ,  Y10S623/901

    Abstract: The present invention relates to a method of polishing an implantable medical device. The method may include positioning an implantable medical device on a support. At least a portion of a surface of the implantable medical device may include a polymer. A fluid may be contacted with at least a portion of the surface of the positioned implantable medical device. In an embodiment, the fluid may be capable of dissolving at least a portion of the polymer at or near the surface of the implantable medical device. The method may further include allowing the fluid to modify at least a portion of the surface of the positioned medical device. A majority of the contacted fluid may be removed from the surface of the implantable medical device. In certain embodiments, the modified portion of the surface may be substantially less thrombogenetic and substantially more mechanically stable than an unmodified surface.

    Abstract translation: 本发明涉及一种抛光可植入医疗器械的方法。 该方法可以包括将可植入医疗装置定位在支撑件上。 可植入医疗装置的表面的至少一部分可以包括聚合物。 流体可以与定位的可植入医疗装置的表面的至少一部分接触。 在一个实施方案中，流体可能能够将聚合物的至少一部分溶解在可植入医疗装置的表面处或附近。 该方法还可以包括允许流体修改定位的医疗装置的表面的至少一部分。 接触流体的大部分可以从可植入医疗装置的表面移除。 在某些实施方案中，表面的改性部分可以比未修饰的表面基本上更少的血栓形成和基本上更机械稳定的。

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