公开(公告)号：US20100286746A1

公开(公告)日：2010-11-11

申请号：US12773647

申请日：2010-05-04

申请人： Ramesh Wariar

发明人： Ramesh Wariar

IPC分类号： A61N1/36

CPC分类号： A61N1/3601 ,  A61B5/0537 ,  A61B5/415 ,  A61B5/418 ,  A61B5/4878 ,  A61N1/205 ,  A61N1/32 ,  A61N1/3627

摘要： System and method of applying electric fields to a patient's lung(s) to reduce pulmonary edema. The system includes a first electrode and a second electrode, at least one of which is associated with the lung. The electric field can be controlled so as to modulate a level of fluid in the lung.

摘要翻译： 将电场施加到患者肺部以减少肺水肿的系统和方法。 该系统包括第一电极和第二电极，其中至少一个与肺相关联。 可以控制电场以便调节肺中的液体水平。

公开(公告)号：US20100010429A1

公开(公告)日：2010-01-14

申请号：US12562730

申请日：2009-09-18

申请人： Robert W. Childers ,  David S. Brown ,  Ramesh Wariar ,  Sujatha Karoor ,  Shahid Din ,  Leo Martis ,  Cody Buckmann ,  Paul Soltys

发明人： Robert W. Childers ,  David S. Brown ,  Ramesh Wariar ,  Sujatha Karoor ,  Shahid Din ,  Leo Martis ,  Cody Buckmann ,  Paul Soltys

IPC分类号： A61M1/28

CPC分类号： A61M1/1696 ,  A61M1/1656 ,  A61M1/1658 ,  A61M1/166 ,  A61M1/28 ,  A61M1/284 ,  A61M1/285 ,  A61M1/287 ,  A61M1/288 ,  A61M2202/0413 ,  A61M2205/12 ,  A61M2205/3306 ,  A61M2205/3327

摘要： A regenerative peritoneal dialysis system includes a dialysis fluid loop; a filter located in the dialysis fluid loop, a first portion of the dialysis fluid sent to the filter rejected by the filter and returned upstream of the filter, a second portion of the dialysis fluid sent to the filter forming permeate, the permeate being rich in urea; and a urea removing apparatus located in the dialysis fluid loop downstream from the filter to receive the permeate and absorb urea from the permeate.

摘要翻译： 再生性腹膜透析系统包括透析液回路; 位于所述透析流体回路中的过滤器，所述透析流体的第一部分被输送到所述过滤器并被所述过滤器排出并返回到所述过滤器的上游，所述透析流体的第二部分被输送到过滤器形成渗透物，所述渗透物富含 尿素 以及尿素去除装置，其位于透析液回路的下游，用于接收渗透物并从渗透物吸收尿素。

公开(公告)号：US20090312659A1

公开(公告)日：2009-12-17

申请号：US12547207

申请日：2009-08-25

申请人： Gerrard M. Carlson ,  Ramesh Wariar ,  Krzysztof Z. Siejko

发明人： Gerrard M. Carlson ,  Ramesh Wariar ,  Krzysztof Z. Siejko

IPC分类号： A61B5/02

CPC分类号： A61N1/36585 ,  A61B5/021 ,  A61B5/0452 ,  A61B7/04 ,  A61M5/1723 ,  A61N1/37

摘要： A system and method for managing preload reserve and tracking the inotropic state of a patient's heart. The S1 heart sound is measured as a proxy for direct measurement of stroke volume. The S3 heart sound may be measured as a proxy for direct measurement of preload level. The S1-S3 pair yield a point on a Frank Starling type of curve, and reveal information regarding the patient's ventricular operating point and inotropic state. As an alternative, or in addition to, measurement of the S3 heart sound, the S4 heart sound may be measured or a direct pressure measurement may be made for the sake of determining the patient's preload level. The aforementioned measurements may be made by a cardiac rhythm management device, such as a pacemaker or implantable defibrillator.

摘要翻译： 一种用于管理预负荷储备并跟踪患者心脏的变力状态的系统和方法。 测量S1心音作为直接测量行程体积的代理。 可以将S3心音测量为用于直接测量预载水平的代理。 S1-S3对在Frank Starling曲线上产生一个点，并显示关于患者的心室手术点和变力状态的信息。 作为S3心音的测量或除了测量S3心音之外，也可以测量S4心音，或者为了确定患者的预压水平可以进行直接的压力测量。 上述测量可以由诸如起搏器或可植入除颤器的心律管理装置进行。

公开(公告)号：US20060155204A1

公开(公告)日：2006-07-13

申请号：US11367852

申请日：2006-03-03

申请人： Ramesh Wariar ,  Gerrard Carlson

发明人： Ramesh Wariar ,  Gerrard Carlson

IPC分类号： A61B5/02

CPC分类号： A61B7/04 ,  A61B5/021 ,  A61B7/00

摘要： A system and method for assessing cardiac performance through cardiac vibration monitoring is described. Cardiac vibration measures are directly collected through an implantable medical device. Cardiac events including at least one first heart sound reflected by the cardiac vibration measures are identified. The first heart sound is correlated to cardiac dimensional measures relative to performance of an intrathoracic pressure maneuver. The cardiac dimensional measures are grouped into at least one measures set corresponding to a temporal phase of the intrathoracic pressure maneuver. The at least one cardiac dimensional measures set is evaluated against a cardiac dimensional trend for the corresponding intrathoracic pressure maneuver temporal phase to represent cardiac performance.

摘要翻译： 描述了通过心脏振动监测来评估心脏性能的系统和方法。 通过植入式医疗设备直接收集心脏振动。 识别心脏事件，包括由心脏振动测量反射的至少一个第一心音。 第一个心音与胸腔内压力作用的心脏尺寸相关。 心脏尺寸测量被分组为对应于胸内压力操纵的时间相位的至少一个测量组。 针对相应的胸内压力机动时间阶段的心脏尺寸趋势来评估至少一个心脏尺寸测量集合以表示心脏性能。

公开(公告)号：US07002670B2

公开(公告)日：2006-02-21

申请号：US10167796

申请日：2002-06-12

申请人： Ramesh Wariar ,  Li Pan

发明人： Ramesh Wariar ,  Li Pan

IPC分类号： G01N33/48

CPC分类号： C12Q1/34 ,  G01N21/05 ,  G01N21/75 ,  G01N21/85

摘要： An improved optical sensor and method for measuring concentration of a chemical constituent where measurement interference from other chemical compounds is present in the solution is provided. More specifically, the invention relates to a system for measuring the amount of creatinine in effluent dialysate during, before, or following a kidney dialysis procedure and a method for using the same. Alternatively, the method may be used with blood and other body fluids or solutions that contact the patient. The system may use an enzyme or other chemical process to specifically remove or convert an analyte with an intrinsic optical absorbance. By measuring the absorbance before and after the chemical process the analyte can be measured with high accuracy and specificity. The method may be extended to multiple analyte measurements using cascaded chemical processes.

公开(公告)号：US10098584B2

公开(公告)日：2018-10-16

申请号：US13366473

申请日：2012-02-06

申请人： Robert J. Sweeney ,  Ramesh Wariar ,  Julie A. Thompson

发明人： Robert J. Sweeney ,  Ramesh Wariar ,  Julie A. Thompson

IPC分类号： A61B5/053 ,  A61B5/00 ,  A61B5/11 ,  A61B5/024 ,  A61B5/08 ,  A61N1/362 ,  A61N1/365 ,  A61N1/37

摘要： Systems and methods to monitor an improvement of a subject's physiological condition using a goal improvement profile are described. In an example, a physiological condition of a subject can be compared to a goal improvement profile, where the profile includes at least one target condition indicative of an improved physiological condition detectable using a physiological sensor signal, and a target time when the subject is expected to reach the target condition, where the comparison can be used to indicate whether the subject has met the target condition by the target time.

公开(公告)号：US08920356B2

公开(公告)日：2014-12-30

申请号：US13173828

申请日：2011-06-30

申请人： Sherwin Shang ,  Ramesh Wariar ,  Angel Lasso ,  George Lamberson ,  Dan F. Marcquenski, Jr. ,  Jan Jensen ,  David Kuhn ,  Raf Castellanos

发明人： Sherwin Shang ,  Ramesh Wariar ,  Angel Lasso ,  George Lamberson ,  Dan F. Marcquenski, Jr. ,  Jan Jensen ,  David Kuhn ,  Raf Castellanos

IPC分类号： A61M37/00 ,  C02F1/44 ,  G01N27/10 ,  G01N27/07 ,  A61M1/36 ,  A61M1/16 ,  F16L25/01 ,  G01N33/49 ,  A61M5/168 ,  A61M1/28 ,  A61M39/10

CPC分类号： A61M1/367 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/287 ,  A61M1/3607 ,  A61M1/3653 ,  A61M1/3655 ,  A61M1/3656 ,  A61M1/3659 ,  A61M1/3661 ,  A61M1/3669 ,  A61M5/16831 ,  A61M39/10 ,  A61M2205/0233 ,  A61M2205/13 ,  A61M2205/15 ,  A61M2205/18 ,  A61M2205/3317 ,  A61M2205/3324 ,  A61M2205/3344 ,  A61M2205/50 ,  A61M2205/6027 ,  A61M2230/65 ,  F16L25/01 ,  G01N27/07 ,  G01N27/10 ,  G01N33/49

摘要： A coupler includes a conductive polymer material that is so constructed and arranged to join tubing, wherein the conductive polymer material includes a conductive polymer component selected from the group consisting of polyaniline, polypyrrole, polythiophenes, polyethylenedioxythiophene, poly(p-phenylene vinylene) and mixtures thereof.

摘要翻译： 耦合器包括被构造和布置成连接管道的导电聚合物材料，其中导电聚合物材料包括选自聚苯胺，聚吡咯，聚噻吩，聚亚乙基二氧噻吩，聚（对亚苯基亚乙烯基）和混合物 其中。

公开(公告)号：US08571656B2

公开(公告)日：2013-10-29

申请号：US12966249

申请日：2010-12-13

申请人： Jeffrey E. Stahmann ,  Ramesh Wariar ,  Stephen Ruble

发明人： Jeffrey E. Stahmann ,  Ramesh Wariar ,  Stephen Ruble

IPC分类号： A61N1/00

CPC分类号： A61N1/36585 ,  A61N1/36 ,  A61N1/362 ,  A61N1/3627 ,  A61N1/365

摘要： Intermittent delivery of ventricular pacing pulses synchronized to occur during an atrial diastole time period can be used to provide atrial stretch therapy and augment the production and release of atrial natriuretic hormone.

公开(公告)号：US08457761B2

公开(公告)日：2013-06-04

申请号：US12683553

申请日：2010-01-07

申请人： Ramesh Wariar

发明人： Ramesh Wariar

IPC分类号： A61N1/00

CPC分类号： A61N1/325 ,  A61N1/306 ,  A61N1/36007

摘要： A system and method of applying an electric field to the kidney of a subject can reduce renal salt and water retention through the process of electrophoresis. The system includes a first and a second electrode, at least of which is implantably associated with the kidney. The electric field can be controlled to affect the removal of a first constituent (e.g. sodium) from the kidney while the level of a second constituent (e.g. potassium) is maintained within normal physiological range.

摘要翻译： 将电场施加到受试者的肾脏的系统和方法可以通过电泳过程减少肾盐和保水。 该系统包括第一和第二电极，其至少可植入地与肾相关联。 可以控制电场以影响从肾脏中去除第一组分（例如钠），同时将第二组分（例如钾）的水平保持在正常生理范围内。

公开(公告)号：US08303513B2

公开(公告)日：2012-11-06

申请号：US13279517

申请日：2011-10-24

申请人： Ramesh Wariar ,  Jeffrey E. Stahmann ,  Julie A. Thompson ,  Helen L. Reeve

发明人： Ramesh Wariar ,  Jeffrey E. Stahmann ,  Julie A. Thompson ,  Helen L. Reeve

IPC分类号： A61B5/0205

CPC分类号： A61B5/0205 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/042 ,  A61B5/053 ,  A61B5/145 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4839 ,  A61B5/7239 ,  A61B5/7275 ,  A61B5/746 ,  A61B7/00 ,  A61N1/36139 ,  A61N1/36585 ,  G06F19/00 ,  G16H50/30

摘要： A hospitalization management system including a heart failure analyzer that receives diagnostic data including at least sensor data representative of one or more physiological signals sensed from a hospitalized patient using one or more sensors and assesses risk of rehospitalization for the patient using the diagnostic data. The outcome of the risk assessment is used during and following the patient's hospitalization for reducing the risk of rehospitalization.

摘要翻译： 一种住院治疗系统，包括心力衰竭分析器，其接收至少包括表示使用一个或多个传感器从住院患者感测的一个或多个生理信号的传感器数据的诊断数据，并且使用诊断数据评估患者的再住院风险。 风险评估的结果在患者住院期间和之后用于降低再住院的风险。