公开(公告)号：US06602502B1

公开(公告)日：2003-08-05

申请号：US07699159

申请日：1991-05-13

申请人： Meir Strahilevitz

发明人： Meir Strahilevitz

IPC分类号： A61K3900

CPC分类号： G01N33/94 ,  A61K47/646 ,  A61M1/1696 ,  A61M1/3482 ,  A61M1/3493 ,  B01D15/3809 ,  B01D61/243 ,  B01D69/02 ,  B01D2311/06 ,  C12N9/00 ,  G01N33/54313 ,  Y10S436/816 ,  Y10S436/822 ,  Y10S514/81 ,  Y10S514/812 ,  B01D2311/2688

摘要： Immunoassays of psychoactive drugs including psychotomimetic drugs, narcotic drugs, and tetrahydrocannabinols and treatment methods based on the antigenic properties of protein conjugates of these drugs. These methods are based upon treating the psychoactive substances as haptens and utilizing their protein conjugates to produce antibodies to the psychoactive materials themselves. The immunoassay methods include both agglutination and agglutination-inhibition reactions. The treatment methods include treatment of both exogenous, administered drugs (such as cannabinols, LSD, heroin and morphine) endogenous substances (such as N,N-Dimethyltryptamine and 5-Methoxy-N,N-Dimethyltryptamine.

摘要翻译： 包括精神药物，麻醉药物和四氢大麻酚的精神药物的免疫测定和基于这些药物的蛋白质缀合物的抗原性质的治疗方法。 这些方法基于将精神活性物质作为半抗原并利用其蛋白质缀合物来产生对精神活性物质本身的抗体。 免疫测定方法包括凝集和凝集抑制反应。 治疗方法包括治疗外源性给药药物（如大麻素，LSD，海洛因和吗啡）内源性物质（如N，N-二甲基色胺和5-甲氧基-N，N-二甲基色胺）。

公开(公告)号：US20030029789A1

公开(公告)日：2003-02-13

申请号：US10160483

申请日：2002-05-31

申请人： MICROBAN PRODUCTS COMPANY

发明人： Arvind S. Patil

IPC分类号： B01D039/16

CPC分类号： A61L2/022 ,  A61L2/16 ,  B01D29/216 ,  B01D29/58 ,  B01D39/1607 ,  B01D39/1661 ,  B01D39/2058 ,  B01D61/025 ,  B01D61/027 ,  B01D61/04 ,  B01D61/10 ,  B01D61/18 ,  B01D63/06 ,  B01D69/02 ,  B01D69/12 ,  B01D2201/088 ,  B01D2239/0407 ,  B01D2239/0442 ,  B01D2239/0485 ,  B01D2239/10 ,  B01D2311/04 ,  B01D2325/48 ,  B29C67/04 ,  C02F1/003 ,  C02F1/283 ,  C02F1/285 ,  C02F1/444 ,  C02F1/50 ,  C02F1/76 ,  C02F9/005 ,  C02F2201/006 ,  C02F2307/06 ,  Y10T428/25 ,  B01D2311/12 ,  B01D2311/2688 ,  B01D2311/2626

摘要： An improved sintered porous thermoplastic filter incorporating a second thermoplastic treated with a non-leaching antimicrobial agent for the purification of liquids. The method of making the filter is also disclosed.

摘要翻译： 一种改进的烧结多孔热塑性过滤器，其结合了用用于净化液体的非浸出抗微生物剂处理的第二种热塑性塑料。 还公开了制造过滤器的方法。

公开(公告)号：US20010011644A1

公开(公告)日：2001-08-09

申请号：US09797703

申请日：2001-03-05

申请人： Daicel Chemical Industries, Ltd.

发明人： Hiroshi Miura

IPC分类号： C02F003/00

CPC分类号： C02F1/441 ,  B01D61/025 ,  B01D61/027 ,  B01D61/04 ,  B01D2311/04 ,  B01D2311/06 ,  C02F1/283 ,  C02F1/444 ,  C02F1/66 ,  C02F1/76 ,  C02F3/00 ,  C02F3/12 ,  C02F9/00 ,  C02F2101/34 ,  C02F2103/36 ,  Y02W10/15 ,  B01D2311/12 ,  B01D2311/2688 ,  B01D2311/18 ,  B01D2311/2626

摘要： An effluent containing sorbic acid or its salt from, for example, a sorbic acid production line is (1) treated with a hypohalogenous acid or its salt, e.g. sodium hypochlorite, or (2) subjected to membrane separation or activated carbon treatment and further to biological treatment such as activated sludge treatment. The required amount of the hypohalogenous acid or salt may for example be about 0.01null10 parts by weight, in terms of effective halogen, based on 100 parts by weight of the effluent. Optionally the effluent thus treated with the hypohalogenous acid or salt is further subjected to a biological treatment such as an activated sludge process.

摘要翻译： 含有例如山梨酸生产线的山梨酸或其盐的流出物是（1）用低光酸性酸或其盐，例如， 次氯酸钠，或（2）进行膜分离或活性炭处理，进一步进行活性污泥处理等生物处理。 基于100重量份的流出物，所需量的次卤酸酸或盐可以例如为有效卤素的约0.01〜10重量份。 任选地，用次卤酸或盐处理的流出物进一步进行生物处理，例如活性污泥法。

公开(公告)号：US3490590A

公开(公告)日：1970-01-20

申请号：US3490590D

申请日：1968-01-02

申请人： DORR OLIVER INC

发明人： DAVIES DAVID S

IPC分类号： B01D61/00 ,  C02F1/28 ,  C02F1/44 ,  C02F3/00 ,  C02F3/02 ,  C02F9/00 ,  B01D13/00 ,  C02C1/02

CPC分类号： C02F9/00 ,  B01D65/08 ,  B01D2311/02 ,  B01D2321/168 ,  C02F1/283 ,  C02F1/441 ,  C02F3/00 ,  B01D2311/2626 ,  B01D2311/2688

公开(公告)号：US20240342665A1

公开(公告)日：2024-10-17

申请号：US18294825

申请日：2022-08-05

申请人： University of Maine System Board of Trustees

发明人： Michael Darin Mason ,  Muhammad Radowan Hossen

IPC分类号： B01D71/10 ,  B01D67/00 ,  B01D69/02 ,  B01D69/14 ,  B01D71/74

CPC分类号： B01D71/10 ,  B01D67/003 ,  B01D69/02 ,  B01D69/14111 ,  B01D71/74 ,  B01D2311/14 ,  B01D2311/2688 ,  B01D2323/18 ,  B01D2323/20 ,  B01D2323/216 ,  B01D2323/21817 ,  B01D2323/21826 ,  B01D2325/40

摘要： The present invention includes membranes comprising one or more cellulosic materials and wetting agent(s), and methods of making such membranes.

公开(公告)号：US20240279620A1

公开(公告)日：2024-08-22

申请号：US18651814

申请日：2024-05-01

申请人： Adaptive Phage Therapeutics, Inc.

发明人： Joseph Robert Fackler ,  Carl Merril ,  Jarrar Haider ,  Viet Dang

IPC分类号： C12N7/00 ,  A61K35/76 ,  A61P31/04 ,  B01D61/20 ,  B01D69/08

CPC分类号： C12N7/00 ,  A61K35/76 ,  A61P31/04 ,  B01D61/20 ,  B01D69/08 ,  B01D2311/2676 ,  B01D2311/2688 ,  B01D2315/10 ,  C12N2795/10132 ,  C12N2795/10151 ,  C12N2795/10232 ,  C12N2795/10251 ,  C12N2795/10332 ,  C12N2795/10351

摘要： A method of recovering viable phage from, for example, a crude phage preparation such as a lysate resulting from amplification of phage in bacterial cell culture is disclosed. The method may be “universal”; that is, applicable to the purification of a broad range of phage species and strains. The phage product resulting from the method may have an acceptably low endotoxin titer (e.g. less than 500 EU/ml) and sufficiently high phage titer (e.g. >1×109 PFU/ml) for use in therapeutic applications.

公开(公告)号：US12049614B2

公开(公告)日：2024-07-30

申请号：US18337146

申请日：2023-06-19

申请人： FUJIFILM CORPORATION

发明人： Shinichi Nakai ,  Yoichi Nagai ,  Nobuyuki Haraguchi ,  Shigehisa Sugiyama

IPC分类号： B01D61/14 ,  B01D61/18 ,  B01D61/58 ,  C12M1/00 ,  C12M1/12 ,  C12M1/26 ,  C12N5/00

CPC分类号： C12M29/04 ,  B01D61/145 ,  B01D61/147 ,  B01D61/149 ,  B01D61/18 ,  B01D61/58 ,  C12M29/10 ,  C12M29/18 ,  C12M33/14 ,  C12M37/02 ,  C12M39/00 ,  C12M47/02 ,  C12N5/0081 ,  B01D2311/2512 ,  B01D2311/2523 ,  B01D2311/2688 ,  B01D2315/08 ,  B01D2315/10 ,  B01D2317/025

摘要： Provided is a cell culture apparatus including a culture vessel that stores a cell suspension containing cells; a first filter part that has a first filter membrane that performs membrane separation treatment on the cell suspension extracted from the culture vessel; a first circulation flow path that allows components blocked by the first filter membrane to return to the culture vessel; a second filter part that has a second filter membrane that performs membrane separation treatment on components of the cell suspension permeated through the first filter membrane; a second circulation flow path that allows components permeated through the second filter membrane to return to the culture vessel; and a recovery flow path that recovers components blocked by the second filter membrane. In the cell culture apparatus, an average hole diameter of the first filter membrane is 20 μm or smaller, and 0

公开(公告)号：US12006517B2

公开(公告)日：2024-06-11

申请号：US17571645

申请日：2022-01-10

申请人： Adaptive Phage Therapeutics, Inc.

发明人： Joseph Robert Fackler ,  Carl Merril ,  Jarrar Haider ,  Viet Dang

IPC分类号： C12N7/00 ,  A61K35/76 ,  A61P31/04 ,  B01D61/20 ,  B01D69/08

CPC分类号： C12N7/00 ,  A61K35/76 ,  A61P31/04 ,  B01D61/20 ,  B01D69/08 ,  B01D2311/2676 ,  B01D2311/2688 ,  B01D2315/10 ,  C12N2795/10132 ,  C12N2795/10151 ,  C12N2795/10232 ,  C12N2795/10251 ,  C12N2795/10332 ,  C12N2795/10351

摘要： A method of recovering viable phage from, for example, a crude phage preparation such as a lysate resulting from amplification of phage in bacterial cell culture is disclosed. The method may be “universal”; that is, applicable to the purification of a broad range of phage species and strains. The phage product resulting from the method may have an acceptably low endotoxin titer (e.g. less than 500 EU/ml) and sufficiently high phage titer (e.g. >1×109 PFU/ml) for use in therapeutic applications.

公开(公告)号：US11952567B2

公开(公告)日：2024-04-09

申请号：US18201025

申请日：2023-05-23

申请人： Global Algae Technology, LLC

发明人： David A. Hazlebeck ,  William Rickman

IPC分类号： B01D63/02 ,  B01D61/14 ,  B01D61/22 ,  B01D63/04 ,  B01D65/02 ,  C12M1/00 ,  C12M1/26 ,  C12M1/34 ,  C12M1/36 ,  C12N1/02 ,  C12N1/12

CPC分类号： C12N1/12 ,  B01D61/146 ,  B01D61/22 ,  B01D63/02 ,  B01D63/04 ,  B01D63/046 ,  B01D65/02 ,  C12M21/02 ,  C12M29/04 ,  C12M29/16 ,  C12M29/18 ,  C12M29/20 ,  C12M33/14 ,  C12M41/32 ,  C12M41/44 ,  C12M41/48 ,  C12M45/00 ,  C12M47/02 ,  C12N1/02 ,  B01D2311/04 ,  B01D2311/06 ,  B01D2311/2626 ,  B01D2311/2688 ,  B01D2313/18 ,  B01D2313/26 ,  B01D2313/50 ,  B01D2315/06 ,  B01D2315/08 ,  B01D2317/02 ,  B01D2317/022 ,  B01D2321/04 ,  B01D2321/18 ,  B01D2321/185 ,  B01D2321/40

摘要： Algae harvesting and cultivating systems and methods for producing high concentrations of algae product with minimal energy. In an embodiment, a dead-end filtration system and method includes at least one tank and a plurality hollow fiber membranes positioned in the at least one tank. An algae medium is pulled through the hollow fiber membranes such that a retentate and a permeate are produced.

公开(公告)号：US20230332085A1

公开(公告)日：2023-10-19

申请号：US18337146

申请日：2023-06-19

申请人： FUJIFILM CORPORATION

发明人： Shinichi NAKAI ,  Yoichi NAGAI ,  Nobuyuki HARAGUCHI ,  Shigehisa SUGIYAMA

IPC分类号： C12M1/00 ,  B01D61/58 ,  C12M1/12 ,  B01D61/14 ,  C12M1/26 ,  C12N5/00 ,  B01D61/18

CPC分类号： C12M29/04 ,  B01D61/145 ,  B01D61/146 ,  B01D61/147 ,  B01D61/18 ,  B01D61/58 ,  C12M29/10 ,  C12M29/18 ,  C12M33/14 ,  C12M37/02 ,  C12M39/00 ,  C12M47/02 ,  C12N5/0081 ,  B01D2311/25 ,  B01D2311/2688 ,  B01D2315/08 ,  B01D2315/10 ,  B01D2317/025

摘要： Provided is a cell culture apparatus including a culture vessel that stores a cell suspension containing cells; a first filter part that has a first filter membrane that performs membrane separation treatment on the cell suspension extracted from the culture vessel; a first circulation flow path that allows components blocked by the first filter membrane to return to the culture vessel; a second filter part that has a second filter membrane that performs membrane separation treatment on components of the cell suspension permeated through the first filter membrane; a second circulation flow path that allows components permeated through the second filter membrane to return to the culture vessel; and a recovery flow path that recovers components blocked by the second filter membrane. In the cell culture apparatus, an average hole diameter of the first filter membrane is 20 µm or smaller, and 0