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149 条记录 (耗时 0.047 秒)

    Fluid processing device, system, kit, and method
    74.
    发明申请
    Fluid processing device, system, kit, and method 审中-公开
    流体处理装置，系统，试剂盒和方法

    公开(公告)号：US20070048189A1

    公开(公告)日：2007-03-01

    申请号：US11212535

    申请日：2005-08-26

    申请人： David Cox ,  Daniel Van Buskirk ,  Abizar Lakdawalla

    发明人： David Cox ,  Daniel Van Buskirk ,  Abizar Lakdawalla

    IPC分类号： B01L3/02

    CPC分类号： B01L3/5025 ,  B01L3/502707 ,  B01L3/502715 ,  B01L7/52 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2300/0887 ,  B01L2400/0406 ,  B01L2400/0409 ,  B01L2400/0487

    摘要： A fluid processing device, system, kit, and method, are provided, for processing a liquid sample. The device can comprise a substrate comprising one or more fluid processing pathways, wherein each pathway can comprise at least a first region, one or more outlet regions, and a channel connecting and in fluid communication with the respective first region and the respective one or more outlet regions, and a cover provided in communication with at least a portion of the top surface of the substrate. The cover can comprise one or more slits each slit respectively aligned with a different respective one of the one or more outlet regions. A removal seal can be applied to the cover to seal the one or more slits.

    摘要翻译： 提供流体处理装置，系统，试剂盒和方法，用于处理液体样品。 该装置可以包括一个包括一个或多个流体处理通道的基板，其中每个通道可以包括至少第一区域，一个或多个出口区域，以及与相应的第一区域和相应的一个或多个流体连通并与流体连通的通道 出口区域，以及设置成与所述基板的顶表面的至少一部分连通的盖。 盖可以包括一个或多个狭缝，每个狭缝分别与一个或多个出口区域中的不同相应的一个对齐。 移除密封件可以施加到盖子上以密封一个或多个狭缝。

    Methods for genetic analysis
    75.
    发明授权
    Methods for genetic analysis 有权
    遗传分析方法

    公开(公告)号：US07127355B2

    公开(公告)日：2006-10-24

    申请号：US10956224

    申请日：2004-09-30

    申请人： David Cox ,  Mark McCamish

    发明人： David Cox ,  Mark McCamish

    IPC分类号： G06F19/00 ,  C12Q1/68

    CPC分类号： G06F19/18 ,  G06F19/24 ,  G06Q50/24

    摘要： Several methods are described for assessing an individual's likelihood of developing or exhibiting a multifactorial trait. The methods include determining a plurality of genotypes for the individual at a plurality of biallelic polymorphic loci, using the genotypes to compute a score for the individual, and comparing the score to at least one threshold value.

    摘要翻译： 描述了用于评估个体发展或表现多因素性状的可能性的几种方法。 所述方法包括使用基因型来计算个体的分数，并将评分与至少一个阈值进行比较来确定个体在多个双重多态性基因座上的多种基因型。

    Method and apparatus for fabricating nanoscale structures
    76.
    发明申请
    Method and apparatus for fabricating nanoscale structures 审中-公开
    制造纳米结构的方法和装置

    公开(公告)号：US20060205109A1

    公开(公告)日：2006-09-14

    申请号：US10547148

    申请日：2004-03-01

    申请人： David Cox ,  Roy Forrest ,  Sembukutiarachilage Silva

    发明人： David Cox ,  Roy Forrest ,  Sembukutiarachilage Silva

    IPC分类号： H01L51/40 ,  H01L29/06

    CPC分类号： B82Y10/00 ,  H01J9/025 ,  H01J2201/30469 ,  H01L51/0048 ,  H01L51/0052

    摘要： An apparatus comprises a scanning electron microscope (SEM) (1) positioned over a manipulation chamber (2) which houses a sample holder (3). The walls of the manipulation chamber (2) support two probes (4, 4a) and the sample holder (3) is able to hold a sample (5), such as carbon nanotubes (10a) carried on a substrate (10). The apparatus can selectively move and apply voltages and currents to the probe or probes (4, 4a) and sample holder (3) under the SEM (1). By controlling the current that is passed across a contact between the probe (4) and a carbon nanotube (10a), a conditioned weld is formed. Likewise, by controlling the current that is passed along a carbon nanotube (10a), the nanotube (10a) can be annealed. Using both the probes (4, 4a) a carbon nanotube can be held and cut at any position along its length. This allows the formation of novel carbon nanotube structures.

    摘要翻译： 一种装置包括位于容纳样品架（3）的操纵室（2）上的扫描电子显微镜（SEM）（1）。 操作室（2）的壁支撑两个探针（4,4a），并且样品保持器（3）能够容纳诸如承载在基底（10）上的碳纳米管（10）的样品（5） 。 该装置可以选择性地移动并在SEM（1）下）向探针或探针（4,4a）和样品架（3）施加电压和电流。 通过控制通过探针（4）和碳纳米管（10a）之间的接触点的电流，形成调节焊缝。 类似地，通过控制沿着碳纳米管（10a）通过的电流，可以对纳米管（10a）进行退火。 使用探针（4,4aa），碳纳米管可以沿其长度的任何位置保持和切割。 这允许形成新的碳纳米管结构。

    Lateral flow format, materials and methods
    77.
    发明申请
    Lateral flow format, materials and methods 有权
    横流形式，材料和方法

    公开(公告)号：US20060040408A1

    公开(公告)日：2006-02-23

    申请号：US11095989

    申请日：2005-03-30

    申请人： Kevin Jones ,  David Cox

    发明人： Kevin Jones ,  David Cox

    IPC分类号： G01N33/543

    CPC分类号： B82Y5/00 ,  B82Y10/00 ,  G01N33/558 ,  Y02A50/53 ,  Y02A50/58 ,  Y10S436/805 ,  Y10S436/81

    摘要： The present invention provides a lateral flow format and materials and methods for using the format in a variety of applications. More particularly, the present invention provides single-layer lateral flow formats, materials and methods for detecting the presence of an analyte using a test strip comprising a dry porous medium comprising a single hydrophilic matrix. Devices are also provided as well as methods of making and using the format. The format is particularly useful for diagnosis of physiological and genetic conditions. In addition, the present invention provides methods and materials for concentrating a reagent in a porous medium.

    摘要翻译： 本发明提供了一种在多种应用中使用格式的横向流格式和材料和方法。 更具体地，本发明提供了单层横向流动形式，用于使用包含包含单个亲水基质的干多孔介质的测试条来检测分析物的存在的材料和方法。 还提供了设备以及制作和使用格式的方法。 该格式对于生理和遗传条件的诊断特别有用。 此外，本发明提供了用于将试剂浓缩在多孔介质中的方法和材料。

    Sondes for locating underground pipes and conduits
    78.
    发明申请
    Sondes for locating underground pipes and conduits 有权
    用于定位地下管道和管道的探头

    公开(公告)号：US20060006875A1

    公开(公告)日：2006-01-12

    申请号：US10886856

    申请日：2004-07-08

    申请人： Mark Olsson ,  Jan Soukup ,  Jeffrey Prsha ,  Michael Turgeon ,  David Cox ,  Ray Merewether

    发明人： Mark Olsson ,  Jan Soukup ,  Jeffrey Prsha ,  Michael Turgeon ,  David Cox ,  Ray Merewether

    IPC分类号： G01V3/08

    CPC分类号： G01V3/081

    摘要： A sonde includes an elongate flexible ferromagnetic core and a coil surrounds an intermediate segment of the core. A housing surrounds and supports the coil. An electronic drive circuit is mounted in the housing for supplying the coil with an electric signal that will induce the core to emit electromagnetic signals at a predetermined strength and frequency that can be remotely detected. Self-contained battery powered float-type and pill-type sondes are also disclosed.

    摘要翻译： 探测器包括细长的柔性铁磁芯和线圈围绕芯的中间段。 壳体围绕并支撑线圈。 电子驱动电路安装在壳体中，用于向线圈提供电信号，该电信号将引起磁芯以能够远程检测的预定强度和频率发射电磁信号。 还公开了独立电池供电的浮动型和药丸型探针。

    Apparatus and method for the precise location of reaction plates
    79.
    发明申请
    Apparatus and method for the precise location of reaction plates 审中-公开
    反应板精确定位的装置和方法

    公开(公告)号：US20050152810A1

    公开(公告)日：2005-07-14

    申请号：US11069322

    申请日：2005-02-28

    申请人： Reid Kowallis ,  David Cox

    发明人： Reid Kowallis ,  David Cox

    IPC分类号： G01N35/02 ,  B01J19/00 ,  B01L3/00 ,  B01L3/02 ,  C40B20/02 ,  C40B60/10 ,  G01N35/10

    CPC分类号： B01L3/5085 ,  G01N35/1065 ,  Y10T436/11 ,  Y10T436/113332 ,  Y10T436/114165 ,  Y10T436/2575

    摘要： Generally, the present invention provides a device and method for accurately locating a multi-well plate at a plate-support location, e.g., a work surface, of an automated laboratory machine, such that one or more acting members of the machine, such as an array of pipette tips, optical sensors, or the like, can accurately address and operate on the individual wells. Interior and/or exterior surface regions of one or more wells of a multi-well plate are used as the primary plate features engaged by locating structure of the machine. In one particular embodiment one or more upwardly tapered projections extend from a plate-support surface of a plate-handling machine for mating engagement with the exterior surface regions of one or more wells. In another embodiment, the exterior surface regions along one or more well bottoms are engagingly received within bores, or other receiving structure, formed on the plate-support surface of a machine. In a further embodiment, one or more downwardly extending projections depend from an acting-member support, along with the acting members of a machine. Introduction of the projections into some of the wells of a multi-well plate serves to align the acting members with the plate's other wells. A biasing assembly can be used to press together the engaging surface regions of the wells and the locating structures of the machine.

    摘要翻译： 通常，本发明提供了一种用于在自动化实验室机器的板支撑位置（例如工作表面）处精确地定位多孔板的装置和方法，使得机器的一个或多个作用构件，例如 移液管尖端，光学传感器等的阵列可以精确地解决和操作各个井。 使用多孔板的一个或多个孔的内部和/或外部表面区域作为通过定位机器的结构而接合的主要板材特征。 在一个特定实施例中，一个或多个向上锥形突起从板处理机的板支撑表面延伸，用于与一个或多个井的外表面区域配合接合。 在另一个实施例中，沿着一个或多个井底的外表面区域接合地容纳在形成在机器的板支撑表面上的孔或其它接收结构内。 在另一个实施例中，一个或多个向下延伸的突起与作用构件支撑件一起，与机器的作用构件一起。 将突出物引入多孔板的一些孔中用于使作用构件与板的其它孔对齐。 偏置组件可用于将井的接合表面区域和机器的定位结构压在一起。

    Method for generating and using a transformer model
    80.
    发明申请
    Method for generating and using a transformer model 审中-公开
    用于生成和使用变压器模型的方法

    公开(公告)号：US20050096886A1

    公开(公告)日：2005-05-05

    申请号：US10699217

    申请日：2003-10-31

    申请人： Karen Smiley ,  John Sutton ,  Thomas Long ,  David Cox

    发明人： Karen Smiley ,  John Sutton ,  Thomas Long ,  David Cox

    IPC分类号： G06F20060101 ,  G06F17/10 ,  G06F17/50

    CPC分类号： G06F17/5036

    摘要： A preferred method for generating a transformer model includes defining a data base by selecting a first and a second set of parameters for inclusion in the data base, the first set of parameters being representative of at least one of as-designed and as-built transformer data, the second set of parameters being representative of transformer performance data. The preferred method also includes storing data from a plurality of transformers in the data base, the data from a plurality of transformers corresponding to the first and second sets of parameters. The preferred method further includes determining interrelationships between the first and second sets of parameters by analyzing the data from a plurality of transformers using multivariate statistical analysis.

    摘要翻译： 用于生成变压器模型的优选方法包括通过选择用于包含在数据库中的第一和第二组参数来定义数据库，第一组参数表示至少一个设计和构建的变压器 数据，第二组参数代表变压器性能数据。 优选方法还包括从数据库中的多个变压器存储来自与第一和第二组参数对应的多个变压器的数据。 优选方法还包括通过使用多变量统计分析分析来自多个变压器的数据来确定第一组参数和第二组参数之间的相互关系。