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公开(公告)号：US20080208103A1
公开(公告)日：2008-08-28
申请号：US11871680
申请日：2007-10-12
CPC分类号： F04B53/10 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1087 , A61M1/1096 , A61M1/16 , A61M1/1605 , A61M1/1639 , A61M1/1656 , A61M1/1664 , A61M1/1666 , A61M1/287 , A61M2205/12 , A61M2205/128 , A61M2205/3317 , A61M2205/3324 , A61M2205/3368 , F04B7/02 , F04B9/109 , F04B13/02 , F04B23/06 , F04B41/06 , F04B43/00 , F04B43/02 , F04B43/06 , F04B43/073 , F04B43/0733 , F04B43/0736 , F04B45/02 , F04B45/0536 , F04B49/22 , F04B53/06 , F04B53/16 , F17D3/00 , Y10T137/0324 , Y10T137/0379 , Y10T137/2521 , Y10T137/85978 , Y10T137/86139
摘要： A pump cassette is disclosed. The pump cassette includes a housing having at least, one fluid inlet line and at least one fluid outlet line. The cassette also includes at least one reciprocating pressure displacement membrane pump within the housing. The pressure pump pumps a fluid from the fluid inlet line to the fluid outlet line. A hollow spike is also included on the housing as well as at least one metering pump The metering pump is fluidly connected to the hollow spike on the housing and to a metering pump fluid line. The metering pump fluid line is fluidly connected to the fluid outlet line.
摘要翻译： 公开了一种泵盒。 泵盒包括具有至少一个流体入口管线和至少一个流体出口管线的壳体。 该盒还包括在壳体内的至少一个往复式压力位移膜泵。 压力泵将流体从流体入口管泵送到流体出口管线。 外壳上还包括一个中空尖钉以及至少一个计量泵。计量泵流体连接到外壳上的中空尖头和计量泵流体管线。 计量泵流体管线流体地连接到流体出口管线。
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公开(公告)号：US20080110523A1
公开(公告)日：2008-05-15
申请号：US11927101
申请日：2007-10-29
申请人： Jason D. Demers , James D. Dale , Brian Tracey , David W. McGill , Larry B. Gray
发明人： Jason D. Demers , James D. Dale , Brian Tracey , David W. McGill , Larry B. Gray
CPC分类号： B01F13/1013 , A61M1/0281 , A61M1/3687 , A61M2205/12 , B01F13/1016 , B01F15/0202 , B01F2015/0221
摘要： A system, device, and method for mixing a substance with a liquid pumps the liquid into a container of the substance to produce a solution. The container may be part of a container assembly including a port assembly for coupling with the container to produce an inlet and/or and outlet port for the container. The container assembly may be received within a receiving chamber for causing the coupling. The solution may be permitted to flow out of the outlet port when the solution rises within the container to a level of the outlet port so that the substance is partially diluted before flowing out of the outlet port.
摘要翻译： 用于将物质与液体混合的系统，装置和方法将液体泵送到物质的容器中以产生溶液。 容器可以是容器组件的一部分，其包括用于与容器联接以产生用于容器的入口和/或出口的端口组件。 容器组件可以被容纳在接收室内以引起联接。 当溶液在容器内升高到出口端口的水平面时，溶液可能被允许流出出口，使得物质在流出出口之前被部分地稀释。
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公开(公告)号：US09028440B2
公开(公告)日：2015-05-12
申请号：US12864293
申请日：2009-01-23
CPC分类号： A61M1/16 , A61M1/28 , A61M1/281 , A61M1/282 , A61M1/288 , A61M5/16809 , A61M5/16813 , A61M5/16827 , A61M39/1011 , A61M39/105 , A61M39/20 , A61M39/28 , A61M39/281 , A61M2039/1066 , A61M2205/12 , A61M2205/123 , A61M2205/127 , A61M2205/128 , A61M2205/13 , A61M2205/14 , A61M2205/3306 , A61M2205/3331 , A61M2205/3334 , A61M2205/3379 , A61M2205/36 , A61M2205/502 , A61M2209/08 , F04B43/02 , F04B43/08 , F04B43/086 , Y02A90/26
摘要： An occluder, and methods for occlusion, that employs first and second opposed occluding members associated with each other, a tube contacting member connected to, or comprising at least a portion of, at least one of the first and second occluding members, and a force actuator constructed and positioned to apply a force to at least one of the first and second occluding members. Application of the force by the force actuator may cause the tube contacting member to move between a tube occluding and an open position. A release member may be configured and positioned to enable an operator to manually move the tube contacting member from the tube occluding position to the open position even with no force applied to the at least one of the first and second occluding members by the force actuator. In one embodiment, the force actuator may apply a force sufficient to bend both the first and second occluding members, so that upon application of the force by the force actuator (such as an air bladder), the first and second occluding members (e.g., spring plates pivotally connected at opposite ends) bend and the tube contacting member may move between the tube occluding and the open position.
摘要翻译： 闭塞器和闭塞方法，其采用彼此相关联的第一和第二相对的阻塞构件，连接到或包括第一和第二闭塞构件中的至少一个的至少一部分的管接触构件，以及力 致动器构造和定位成向第一和第二闭塞构件中的至少一个施加力。 由力致动器施加的力可能导致管接触构件在闭塞管和打开位置之间移动。 释放构件可以被配置和定位成使得操作者能够通过力促动器将操作者手动地将管接触构件从管堵塞位置移动到打开位置，即使没有施加到第一和第二阻塞构件中的至少一个的力。 在一个实施例中，力致动器可以施加足以弯曲第一和第二闭塞构件的力，使得在由力致动器（例如气囊）施加力时，第一和第二闭塞构件（例如， 在相对端枢转地连接的弹簧板）弯曲并且管接触构件可在管闭塞和打开位置之间移动。
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公开(公告)号：US08968232B2
公开(公告)日：2015-03-03
申请号：US13018054
申请日：2011-01-31
申请人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
发明人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
IPC分类号： A61M37/00 , C02F1/44 , A61M1/00 , A61M1/10 , A61M1/36 , F04B43/06 , F04B43/073 , G01K1/08 , G01K1/16 , G01M3/18 , A61F7/12
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
摘要翻译： 本发明的实施例一般涉及可用于加热或冷却诸如血液的流体的热交换器系统。 可以在这种系统中使用提供低剪切和低湍流的杓式泵，特别是用于泵送血液的系统。 用于加热血液或其他液体的某种热交换器系统可用于提供全身热疗治疗或局部高热化疗治疗。 可以使用一次性单元来将流体路径与流体控制系统分离。 一次性单元通常包括由基本单元中的相应热交换器接收的热交换器部件。 泵送通过热交换器部件的流体被热交换器加热。
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公开(公告)号：US08721884B2
公开(公告)日：2014-05-13
申请号：US13569623
申请日：2012-08-08
CPC分类号： A61M1/3672 , A61M1/16 , A61M1/1601 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , Y10T137/87893
摘要： Disclosed are hemodialysis and similar dialysis systems including fluid flow circuits. Hemodialysis systems may include a blood flow path, and a dialysate flow path including balancing, mixing, and/or a directing circuits. Preparation of dialysate may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit and/or the various fluid flow paths may be isolated from electrical components. A gas supply may be provided that, when activated, is able to urge dialysate through the dialyzer and blood back to the patient. Such a system may be useful during a power failure. The hemodialysis system may also include fluid handling devices, such as pumps, valves, mixers, etc., actuated using a control fluid. The control fluid may be delivered to the fluid handling devices using a detachable external pump. The fluid handling devices may have a spheroid shape with a diaphragm dividing it into two compartments.
摘要翻译： 公开了血液透析和类似的透析系统，包括流体流动回路。 血液透析系统可以包括血液流路和包括平衡，混合和/或定向电路的透析液流动路径。 透析液的制备可能与患者透析分离。 电路可以被定义在一个或多个盒中。 流体回路和/或各种流体流动路径可以与电气部件隔离。 可以提供气体供应，当被激活时，能够通过透析器促使透析液和血液返回给患者。 这种系统在电源故障期间可能是有用的。 血液透析系统还可以包括使用控制流体致动的流体处理装置，例如泵，阀，混合器等。 可以使用可拆卸的外部泵将控制流体输送到流体处理装置。 流体处理装置可以具有球形形状，其中隔膜将其分成两个隔室。
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公开(公告)号：US20130032536A1
公开(公告)日：2013-02-07
申请号：US13569623
申请日：2012-08-08
CPC分类号： A61M1/3672 , A61M1/16 , A61M1/1601 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , Y10T137/87893
摘要： Disclosed are hemodialysis and similar dialysis systems including fluid flow circuits. Hemodialysis systems may include a blood flow path, and a dialysate flow path including balancing, mixing, and/or a directing circuits. Preparation of dialysate may be decoupled from patient dialysis. Circuits may be defined within one or more cassettes. The fluid circuit and/or the various fluid flow paths may be isolated from electrical components. A gas supply may be provided that, when activated, is able to urge dialysate through the dialyzer and blood back to the patient. Such a system may be useful during a power failure. The hemodialysis system may also include fluid handling devices, such as pumps, valves, mixers, etc., actuated using a control fluid. The control fluid may be delivered to the fluid handling devices using a detachable external pump. The fluid handling devices may have a spheroid shape with a diaphragm dividing it into two compartments.
摘要翻译： 公开了血液透析和类似的透析系统，包括流体流动回路。 血液透析系统可以包括血液流路和包括平衡，混合和/或定向电路的透析液流动路径。 透析液的制备可能与患者透析分离。 电路可以被定义在一个或多个盒中。 流体回路和/或各种流体流动路径可以与电气部件隔离。 可以提供气体供应，当被激活时，能够通过透析器促使透析液和血液返回给患者。 这种系统在电源故障期间可能是有用的。 血液透析系统还可以包括使用控制流体致动的流体处理装置，例如泵，阀，混合器等。 可以使用可拆卸的外部泵将控制流体输送到流体处理装置。 流体处理装置可以具有球形形状，其中隔膜将其分成两个隔室。
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公开(公告)号：US08292594B2
公开(公告)日：2012-10-23
申请号：US11787212
申请日：2007-04-13
申请人： Brian Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
发明人： Brian Tracey , Larry B. Gray , Jason A. Demers , James D. Dale , N. Christopher Perry , Michael J. Wilt , Scott A. Leonard
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Certain types of reciprocating positive-displacement pumps (which may be referred to hereinafter as “pods,” “pump pods,” or “pod pumps”) are used to pump fluids, such as a biological fluid (e.g., blood or peritoneal fluid), a therapeutic fluid (e.g., a medication solution), or a surfactant fluid. The pumps may be configured specifically to impart low shear forces and low turbulence on the fluid as the fluid is pumped from an inlet to an outlet. Such pumps may be particularly useful in pumping fluids that may be damaged by such shear forces (e.g., blood, and particularly heated blood, which is prone to hemolysis) or turbulence (e.g., surfactants or other fluids that may foam or otherwise be damaged or become unstable in the presence of turbulence).
摘要翻译： 使用某些类型的往复式正排量泵（以下称为荚果，泵荚果或荚果泵）来泵送流体，例如生物流体（例如血液或腹膜液），治疗流体（例如， ，药物溶液）或表面活性剂流体。 泵可以被特别地构造成当流体从入口泵送到出口时在液体上施加低剪切力和低湍流。 这种泵可能特别可用于泵送可能被这种剪切力（例如，血液，特别是加热的血液易于溶血）或湍流（例如，可能发泡或以其他方式损坏的表面活性剂或其它流体） 在湍流的存在下变得不稳定）。
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公开(公告)号：US08246826B2
公开(公告)日：2012-08-21
申请号：US12072908
申请日：2008-02-27
CPC分类号： A61M1/3672 , A61M1/16 , A61M1/1601 , A61M1/1621 , A61M1/1654 , A61M1/1694 , A61M1/267 , A61M1/3413 , A61M1/3424 , A61M1/3609 , A61M1/3621 , A61M1/3638 , A61M1/3643 , A61M1/3644 , A61M1/3646 , A61M1/3649 , A61M1/365 , A61M1/3652 , A61M2205/12 , A61M2205/123 , A61M2205/128 , A61M2205/15 , A61M2205/3317 , A61M2205/3324 , A61M2205/3331 , A61M2205/3334 , A61M2205/3368 , A61M2205/36 , A61M2205/505 , Y10T137/87893
摘要： The present invention generally relates to hemodialysis and similar dialysis systems, including a variety of systems and methods that would make hemodialysis more efficient, easier, and/or more affordable. One aspect of the invention is generally directed to new fluid circuits for fluid flow. In one set of embodiments, a hemodialysis system may include a blood flow path and a dialysate flow path, where the dialysate flow path includes one or more of a balancing circuit, a mixing circuit, and/or a directing circuit. Preparation of dialysate by the preparation circuit, in some instances, may be decoupled from patient dialysis. In some cases, the circuits are defined, at least partially, within one or more cassettes, optionally interconnected with conduits, pumps, or the like. In one embodiment, the fluid circuit and/or the various fluid flow paths may be at least partially isolated, spatially and/or thermally, from electrical components of the hemodialysis system. In some cases, a gas supply may be provided in fluid communication with the dialysate flow path and/or the dialyzer that, when activated, is able to urge dialysate to pass through the dialyzer and urge blood in the blood flow path back to the patient. Such a system may be useful, for example, in certain emergency situations (e.g., a power failure) where it is desirable to return as much blood to the patient as possible. The hemodialysis system may also include, in another aspect of the invention, one or more fluid handling devices, such as pumps, valves, mixers, or the like, which can be actuated using a control fluid, such as air. In some cases, the control fluid may be delivered to the fluid handling devices using an external pump or other device, which may be detachable in certain instances. In one embodiment, one or more of the fluid handling devices may be generally rigid (e.g., having a spheroid shape), optionally with a diaphragm contained within the device, dividing it into first and second compartments.
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79.发明授权公开(公告)号：US08105265B2
公开(公告)日：2012-01-31
申请号：US12249668
申请日：2008-10-10
IPC分类号： A61M37/00
CPC分类号： A61M1/3621 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1062 , A61M1/1086 , A61M1/3666 , A61M1/3667 , A61M2205/127 , Y10T137/86035
摘要： A cardiopulmonary bypass system utilizing membrane-based reciprocating positive displacement blood pumps (“pod pumps”). In one aspect, the pod pumps are constructed to provide reduced shear forces on the blood being pumped. In another aspect blood flow through the pod pumps can be controlled by a controller using information from pressure sensors in the control chamber of the pod pumps. In another aspect, the pod pumps are included on a disposable unit that can be received and held by a receptacle means on a base unit, the base unit also providing pressurized control fluid to the pod pumps on the disposable unit through the receptacle means.
摘要翻译： 一种使用膜式往复式正位移血液泵（“荚式泵”）的体外循环系统。 在一个方面，荚果泵构造成在被泵送的血液上提供减小的剪切力。 在另一方面，通过容器泵的血液流动可以由控制器使用来自荚果泵的控制室中的压力传感器的信息来控制。 在另一方面，所述荚式泵包括在一次性单元中，所述一次性单元可以由基座单元上的容器装置接收和保持，所述基座单元还通过所述容器装置向所述一次性单元上的所述容器泵提供加压控制流体。
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公开(公告)号：US20110218600A1
公开(公告)日：2011-09-08
申请号：US13018054
申请日：2011-01-31
申请人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
发明人： Dean Kamen , Jason A. Demers , David E. Altobelli , Larry B. Gray , N. Christopher Perry , Brian Tracey , James D. Dale , Dirk A. van der Merwe , Kingston Owens
IPC分类号： A61F7/00
CPC分类号： A61M1/106 , A61F7/12 , A61F2007/0069 , A61F2007/126 , A61M1/1006 , A61M1/1012 , A61M1/1037 , A61M1/1062 , A61M1/1086 , A61M1/1087 , A61M1/1096 , A61M1/3626 , A61M1/369 , A61M2205/12 , A61M2205/127 , A61M2205/27 , A61M2205/3334 , A61M2205/3368 , A61M2205/3606 , A61M2205/3653 , A61M2205/502 , F04B43/0054 , F04B43/06 , F04B43/0736 , G01K1/08 , G01K1/16 , G01M3/188
摘要： Embodiments of the present invention relate generally to heat-exchanger systems that can be used to heat or cool a fluid such as blood. Pod pumps that provide low shear and low turbulence may be used in such systems, particularly for systems that pump blood. A certain heat-exchanger system used to heat blood or other fluids may be used to provide whole-body hyperthermic treatments or regional hyperthermic chemotherapy treatments. A disposable unit may be used to separate the fluid path from the fluid control systems. The disposable unit typically includes a heat-exchanger component that is received by a corresponding heat exchanger in a base unit. Fluid pumped through the heat-exchanger component is heated by the heat exchanger.
摘要翻译： 本发明的实施例一般涉及可用于加热或冷却诸如血液的流体的热交换器系统。 可以在这种系统中使用提供低剪切和低湍流的杓式泵，特别是用于泵送血液的系统。 用于加热血液或其他液体的某种热交换器系统可用于提供全身热疗治疗或局部高热化疗治疗。 可以使用一次性单元来将流体路径与流体控制系统分离。 一次性单元通常包括由基本单元中的相应热交换器接收的热交换器部件。 泵送通过热交换器部件的流体被热交换器加热。
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