公开(公告)号：US5445963A

公开(公告)日：1995-08-29

申请号：US660830

申请日：1991-02-26

申请人： Neil W. Boaz

发明人： Neil W. Boaz

IPC分类号： C07B57/00 ,  C07C303/44 ,  C07C309/73 ,  C07C309/74 ,  C07C309/76 ,  C12P41/00

CPC分类号： C07B57/00 ,  C07C303/44 ,  C12P11/00 ,  C12P41/003 ,  C07B2200/07 ,  Y10S435/814 ,  Y10S435/874 ,  Y10S435/876

摘要： A process is disclosed for the separation of an enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene and an enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene from a first mixture containing both compounds. The process includes the steps of:(a) forming a solution of the mixture in an organic solvent;(b) bringing the solution formed in (a) to a temperature wherein most of the enantiomerically enriched 1-tosyloxy-2-hydroxy-3-butene precipates, leaving in solution most of the enantiomerically enriched 1-tosyloxy-2-acyloxy-3-butene; and(c) separating the precipitate formed in (b) from the solution.

摘要翻译： 公开了从含有两种化合物的第一混合物分离对映体富集的1-甲氧基-2-酰氧基-3-丁烯和对映体富集的1-甲苯氧基-2-羟基-3-丁烯的方法。 该方法包括以下步骤：（a）在有机溶剂中形成混合物的溶液; （b）使（a）中形成的溶液达到大部分对映体富集的1-甲苯氧基-2-羟基-3-丁烯沉淀的温度，在溶液中留下大部分对映体富集的1-甲氧基-2-酰氧基-3 丁烯 和（c）将（b）中形成的沉淀物与溶液分离。

公开(公告)号：US5413935A

公开(公告)日：1995-05-09

申请号：US106182

申请日：1993-03-24

申请人： Ramesh N. Patel ,  Clyde G. McNamee ,  Laszlo J. Szarka

发明人： Ramesh N. Patel ,  Clyde G. McNamee ,  Laszlo J. Szarka

IPC分类号： C07D405/06 ,  C12P17/16 ,  C12P41/00

CPC分类号： C07D405/06 ,  C12P17/16 ,  C12P41/004 ,  Y10S435/874 ,  Y10S435/876 ,  Y10S435/877

摘要： An enantiomerically pure compound of the formula ##STR1## is prepared when the associated racemic mixture is reacted with an acrylating agent R.sup.3 --C(O)--O--R in the presence of a microorganism or enzyme derived therefrom capable of catalyzing transesterification of an alcohol. X.sup.1 and X.sup.2 are each independently halogen, R is alkyl, R.sup.1 and R.sup.2 are each independently alkyl, cycloalkyl, aralkyl or aryl and R.sup.3 is alkyl, cycloalkyl, aryl or aralkyl.

摘要翻译： 当相关的外消旋混合物在丙烯酸酯化剂R3-C（O）-O-R的存在下，在能够催化醇的酯交换反应的微生物或酶衍生物的存在下，制备式“IMAGE”的对映异构体纯的化合物。 X 1和X 2各自独立地为卤素，R为烷基，R 1和R 2各自独立地为烷基，环烷基，芳烷基或芳基，R 3为烷基，环烷基，芳基或芳烷基。

公开(公告)号：US5348742A

公开(公告)日：1994-09-20

申请号：US46464

申请日：1993-04-13

申请人： Charles R. Howell ,  J. Ole Becker ,  Stephen T. Lam ,  James M. Ligon

发明人： Charles R. Howell ,  J. Ole Becker ,  Stephen T. Lam ,  James M. Ligon

IPC分类号： A01N63/00 ,  C12N1/21 ,  C12N15/52 ,  C05F11/08 ,  C12N1/00 ,  C12N1/20

CPC分类号： C12R1/39 ,  A01N63/00 ,  C12N15/52 ,  Y10S435/822 ,  Y10S435/876

摘要： Purified bacterial strains that are effective for the inhibition of plant pathogens, including the fungi Rhizoctonia solani and Pythium ultimum have been isolated. These strains are useful as biocontrol agents, and can be used to produce antifungal metabolites, such as antibiotic compounds, active against the plant pathogenic fungi Rhizoctonia solani and Pythium ultimum. Both the purified bacterial strains and the antibiotic compounds can be used as active agents for biocontrol compositions.

摘要翻译： 已经分离了对抑制植物病原体有效的纯化菌株，包括真菌丝核菌（Rhizoctonia solani）和腐霉菌（Pythium ultimum）。 这些菌株可用作生物防治剂，可用于生产抗真菌代谢物，如抗生素化合物，对植物致病真菌丝核菌（Rhizoctonia solani）和腐霉菌（Pythium ultimum）有活性。 纯化的细菌菌株和抗生素化合物均可用作生物控制组合物的活性剂。

公开(公告)号：US5336492A

公开(公告)日：1994-08-09

申请号：US153840

申请日：1993-11-17

申请人： Jewel Payne ,  August J. Sick

发明人： Jewel Payne ,  August J. Sick

IPC分类号： C12N15/09 ,  A01N63/00 ,  A61K38/00 ,  C07K14/00 ,  C07K14/195 ,  C07K14/325 ,  C07K14/41 ,  C12N1/15 ,  C12N1/19 ,  C12N1/20 ,  C12N1/21 ,  C12N15/32 ,  C12N15/82 ,  C12R1/07 ,  C12R1/19 ,  A01N63/02 ,  C10N1/21

CPC分类号： A01N63/00 ,  C07K14/325 ,  C12N15/8286 ,  A61K38/00 ,  Y10S435/832 ,  Y10S435/848 ,  Y10S435/874 ,  Y10S435/876

摘要： A novel B.t. toxin gene toxic to lepidopteran insects has been cloned from a novel lepidopteran-active B. thuringiensis microbe, The DNA encoding the B.t. toxin can be used to transform various prokaryotic and eukaryotic microbes to express the B.t. toxin. These recombinant microbes can be used to control lepidopteran insects in various environments.

摘要翻译： 小说B.t. 毒素对鳞翅目昆虫有毒的基因已经从一种新型的鳞翅目昆虫激活的苏云金芽孢杆菌微生物克隆，编码B.t. 毒素可用于转化各种原核和真核微生物，以表达B.t. 毒素。 这些重组微生物可用于控制各种环境中的鳞翅目昆虫。

公开(公告)号：US5290910A

公开(公告)日：1994-03-01

申请号：US921137

申请日：1992-07-29

申请人： Takeshi Shiotani ,  Genta Kobayashi

发明人： Takeshi Shiotani ,  Genta Kobayashi

IPC分类号： C08G63/06 ,  C08L101/16 ,  C12N1/20 ,  C12P7/62 ,  C12R1/38

CPC分类号： C12R1/39 ,  C08G63/06 ,  C12P7/625 ,  Y10S435/822 ,  Y10S435/874 ,  Y10S435/876

摘要： The present invention is directed to a copolymer containing a unit represented by Formula (1): ##STR1## wherein Y represents a hydrocarbon residue having 1 to 13 carbon atoms which may have 1 to 4 double bonds. A method for production thereof comprises the steps of culturing microorganisms of the genus Pseudomonas under limitation of nutrients other than carbon sources using a medium containing long-chain fatty acids having 14 to 22 carbon atoms or lower alcohol esters thereof, or triglycerides comprising long-chain fatty acids having 14 to 22 carbon atoms as carbon sources; washing the bacterial cells after completion of cultivation; extracting the bacterial cells; and recovering a polyester from the extracts.

摘要翻译： 本发明涉及含有由式（1）表示的单元的共聚物：（*化学结构*）（1）其中Y表示可具有1至4个双键的具有1至13个碳原子的烃残基。 其生产方法包括以下步骤：使用含有14-22个碳原子的长链脂肪酸或其低级醇酯的介质或包含长链的甘油三酸酯培养除了碳源以外的营养物质的限制下的假单胞菌属的微生物 具有14-22个碳原子的脂肪酸作为碳源; 完成培养后洗涤细菌细胞; 提取细菌细胞; 并从提取物中回收聚酯。

公开(公告)号：US5260302A

公开(公告)日：1993-11-09

申请号：US597665

申请日：1990-10-17

申请人： Maria Fattori ,  Stefaan R. M. Horemans ,  Marc Lefebvre ,  Keith A. Powell ,  Annabel Renwick

发明人： Maria Fattori ,  Stefaan R. M. Horemans ,  Marc Lefebvre ,  Keith A. Powell ,  Annabel Renwick

IPC分类号： A01N63/02 ,  A01N63/00 ,  C12N1/20 ,  C12Q1/00 ,  C12Q1/18 ,  C12R1/39 ,  C12Q1/04

CPC分类号： C12R1/39 ,  A01N63/00 ,  C12Q1/18 ,  Y10S435/874 ,  Y10S435/876 ,  Y10S435/911 ,  Y10S435/929 ,  Y10S435/939

摘要： A method for the screening of potential antifungal agents comprises testing the inhibitory effect of the potential antifungal agent in two tests, a first test for inhibition of pathogen development in sterilised soil infested with mycelium of Pythium spp and a second test against for inhibition of disease development in a growing plant of a species susceptible to disease from damping-off disease complex in the presence of the said complex, identifying agents giving potential inhibitory effect in both tests compared with control and submitting same for further examination. Using this method four particularly useful microorganisms which display antifungal activity in a wide spectrum, shown in further testing and in field trials, of disease fungi have been provided. Methods of using such microorganisms and compositions and compositions containing same are also described.

摘要翻译： 用于筛选潜在抗真菌剂的方法包括在两次测试中测试潜在的抗真菌剂的抑制作用，第一次测试用腐霉菌菌丝体侵染的灭菌土壤中的病原体发育的抑制和针对抑制疾病发展的第二次试验 在所述复合物存在下，在一种易受阻尼疾病复合物疾病影响的物种的生长植物中，鉴定出与对照相比较，两种试验中提供潜在的抑制作用，并提交给进一步检查。 已经提供了四种特别有用的微生物，其在广谱范围（在进一步测试和现场试验中显示）具有抗真菌活性。 还描述了使用这种微生物的方法和含有它们的组合物和组合物。

公开(公告)号：US5248610A

公开(公告)日：1993-09-28

申请号：US708868

申请日：1991-05-31

申请人： Kazutoshi Miyazawa ,  Naoyuki Yoshida

发明人： Kazutoshi Miyazawa ,  Naoyuki Yoshida

IPC分类号： C12P7/62 ,  C12P41/00

CPC分类号： C12P7/62 ,  C12P41/004 ,  Y10S435/876

摘要： The invention provides a process for producing an optically active .alpha.-hydroxyester by a biochemical method, and the process comprises reacting an ester with a racemic compound in the presence of a lipase to obtain the following compound which are useful for starting materials for physiological active materials, functional materials and the like. ##STR1## wherein R is alkyl of 1-5 carbon atoms, A is alkyl of 1-20 carbon atoms, perfluorophenyl, 2-phenylethyl or a specific phenyl group.

公开(公告)号：US5232850A

公开(公告)日：1993-08-03

申请号：US732563

申请日：1991-07-19

申请人： Lester E. Casida, Jr.

发明人： Lester E. Casida, Jr.

IPC分类号： A01N63/00

CPC分类号： C12R1/38 ,  A01N63/00 ,  Y10S435/874 ,  Y10S435/875 ,  Y10S435/876 ,  Y10S435/877

摘要： A biologically pure culture of naturally-occurring Pseudomonas strain 679-2 is described. This nonobligate bacterial predator microorganism and its extracellular products are useful for the control of many bacterial and fungal diseases of plants. Whole cells of this bacterium and the antimicrobial compounds that it produces are involved in biological control effects. Materials and methods of preparation and application involving Pseudomonas strain 679-2 and its antimicrobial products are described.

摘要翻译： 描述了天然存在的假单胞菌属菌株679-2的生物学纯培养物。 这种非鸟类细菌捕食者微生物及其细胞外产物可用于控制植物的许多细菌和真菌疾病。 该细菌的全细胞及其产生的抗微生物化合物参与生物防治效果。 描述了涉及假单胞菌属菌株679-2及其抗微生物产品的制备和应用的材料和方法。

公开(公告)号：US5182206A

公开(公告)日：1993-01-26

申请号：US804586

申请日：1991-12-10

申请人： Masanori Yamamoto ,  Toshio Nakayama ,  Osamu Fujii ,  Rie Okabe

发明人： Masanori Yamamoto ,  Toshio Nakayama ,  Osamu Fujii ,  Rie Okabe

IPC分类号： C12N1/20 ,  C12P1/04

CPC分类号： C12N1/20 ,  C12P1/04 ,  Y10S435/874 ,  Y10S435/875 ,  Y10S435/876 ,  Y10S435/877

摘要： A novel pyrimine-producing strain belonging to genus Pseudomonas exhibits the following bacteriological properties: denitrification reaction: negative; assimilation of carbon sources:D-arabinose: positiveL-lysine: negativeand a novel pyrimine-producing strain belonging to genus Pseudomonas exhibits the following bacteriological properties: denitrification reaction: negative, assimilation of carbon sources:D-arabinose: positiveL-lysine: positiveThese novel strains produce pyrimine in high yield and if the strains are cultured in a proper culture medium in the presence of an iron salt, a natural red dye, ferropyrimine, can be easily produced and directly be recovered from the culture medium.

摘要翻译： 属于假单胞菌属的一种新型的制药菌具有以下细菌学特性：脱氮反应：阴性; 碳源的同化：D-阿拉伯糖：阳性L-赖氨酸：阴性和属于假单胞菌属的新型嘧啶生成菌株具有以下细菌学特性：脱氮反应：阴性，碳源同化：D-阿拉伯糖：阳性L-赖氨酸 ：阳性这些新菌株以高产量产生嘧啶，如果菌株在铁盐存在下在合适的培养基中培养，则可以容易地生产天然红色染料，铁嘧啶，并直接从培养基中回收。

公开(公告)号：US4849008A

公开(公告)日：1989-07-18

申请号：US899757

申请日：1986-08-21

申请人： Milton N. Schroth ,  Thomas J. Burr

发明人： Milton N. Schroth ,  Thomas J. Burr

IPC分类号： A01N63/00 ,  C12N1/04

CPC分类号： C12R1/38 ,  A01N63/00 ,  C12N1/04 ,  Y10S435/876 ,  Y10S435/877

摘要： Methods and compositions for enhancing the yield of root crops, such as potatoes, sugar beets, radishes and the like, comprise treating the roots, plants, seeds, seed pieces, or soil in which they are to be planted, with a root crop growth promotant bacteria of the genus Pseudomonas.

摘要翻译： 增加根系作物（如马铃薯，甜菜，萝卜等）产量的方法和组合物包括用根作物生长处理要种植的根，植物，种子，种子片或土壤 假单胞菌属的促进细菌。