摘要:
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.
摘要:
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having at least one halogenated hydrocarbon moiety, a biaryl moiety, and at least one heterocyclic moiety, that are useful as such agents.
摘要:
The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.
摘要:
Oxide comprising at least the elements Si and Ti, at least noncrystalline silicon dioxide and at least one crystalline silicate phase which has at least one zeolite structure, with noncrystalline silicon dioxide being applied to at least one crystalline silicate phase having at least one zeolite structure, wherein the oxide has no silicon-carbon bonds.
摘要:
A system and a methodology to improve the end-user quality of service both in terms of response time and reliability for the transport of in-call DTMF signals in wireless systems, particularly in geostationary mobile satellite systems. The methodology encompasses several techniques to provide acceptable end-to-end quality of service for DTMF. A technique is applicable for transport of DTMF in the wireless subscriber to network direction, where DTMF digits are carried in the form of an out-band message. The central part of the technique is to allow multiple key presses in the same message, thereby increasing efficiency and throughput in long-delay environment. Another technique utilizes the vocoder's functionality to carry DTMF in-band, thereby reducing system complexity. The scheme makes the use of an integrated DTMF detector which can classify a given frame of signal into several classes so that the DTMF encoded packet can carry a unique pattern across the air-interface to the voice decoder at AT, which is capable of identifying the pattern. Another technique pertains to the use of a message based DTMF transport between two-ATs on a separate logical channel with a unique Service Access point Identifier (SAPI) providing guaranteed service for DTMF transport in an AT-AT call.
摘要:
Disclosed are novel 4-alkenyl- and 4-alkynyl oxindoles having the formula and the pharmaceutically acceptable salts thereof, wherein R1, R2, R3, a, b, and X are as defined herein. These compounds inhibit cyclin-dependent kinases (CDKs), in particular CDK2. These compounds and their pharmaceutically acceptable salts, and prodrugs of said compounds, are anti-proliferative agents useful in the treatment or control of cell proliferative disorders, in particular cancer, more particularly, the treatment or control of breast and colon tumors. Also disclosed are pharmaceutical compositions containing the compounds of formula I and II as well as intermediates useful in the preparation of the compounds of formula I and II.
摘要:
Disclosed are novel 4-alkenyl- and 4-alkynyl oxindoles having the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2, R.sup.3, a, b, and X are as defined herein. These compounds inhibit cyclin-dependent kinases (CDKs), in particular CDK2. These compounds and their pharmaceutically acceptable salts, and prodrugs of said compounds, are anti-proliferative agents useful in the treatment or control of cell proliferative disorders, in particular cancer, more particularly, the treatment or control of breast and colon tumors. Also disclosed are pharmaceutical compositions containing the compounds of formula I and II as well as intermediates useful in the preparation of the compounds of formula I and II.
摘要:
FIG. 1 is a front, right and top perspective view of a protective case for a watch, showing my new design; FIG. 2 is a rear, left and bottom perspective view thereof; FIG. 3 is a front view thereof; FIG. 4 is a rear view thereof; FIG. 5 is a left side view thereof; FIG. 6 is a right side view thereof; FIG. 7 is a top plan view thereof; and, FIG. 8 is a bottom plan view thereof. The broken lines shown in the drawings illustrate portions of the protective case for a watch that form no part of the claimed design.
摘要:
Imaging spectrometers can be used to generate hyperspectral images for medical diagnoses, contaminant detection, and food safety inspections, among other applications. An exemplary imaging spectrometer includes an integrated position sensing array that measures the relative positions of the interferometer components based on an interference pattern generated by illuminating the interferometer with a reference beam. Such an imaging spectrometer includes a processor that controls the interferometer component position by actuating a voice coil and several piezo-electric elements to align the components with respect to each other and to provide a desired optical path length mismatch between the interferometer arms. In some cases, the processor may use feedback and feed forward control, possibly based on the actuators' transfer functions, for more precise positioning. The processor may also implement adaptive and recursive spectral sampling to reduce the image acquisition period.
摘要:
Provided is a method for preparing a compound represented by Formula I or a salt thereof, wherein Coleophoma empetri F-11899 (FERM BP2635) and/or a mutant strain thereof is cultured in a medium containing amino acid or a salt thereof, an insoluble organic source, and a sugar alcohol, to produce the compound of Formula I or a salt thereof.