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109 条记录 (耗时 0.065 秒)

    SAMPLE PROCESSING UNITS, SYSTEMS, AND RELATED METHODS
    85.
    发明申请
    SAMPLE PROCESSING UNITS, SYSTEMS, AND RELATED METHODS 有权
    样品加工单元，系统和相关方法

    公开(公告)号：US20120058552A1

    公开(公告)日：2012-03-08

    申请号：US13221608

    申请日：2011-08-30

    申请人： Steven A. Hofstadler ,  Jared J. Drader ,  Jose R. Gutierrez ,  Paul J. Gleason ,  Rex O. Bare ,  Robert D. Miller ,  Jeffrey C. Smith

    发明人： Steven A. Hofstadler ,  Jared J. Drader ,  Jose R. Gutierrez ,  Paul J. Gleason ,  Rex O. Bare ,  Robert D. Miller ,  Jeffrey C. Smith

    IPC分类号： C12M1/00 ,  H01J49/26 ,  G01F23/00 ,  G01N31/22 ,  G01N9/00 ,  G01K1/00 ,  G01R27/08 ,  C07H21/00 ,  G01L7/00

    CPC分类号： G01N1/10 ,  G01N1/02 ,  G01N35/0098 ,  G01N35/025 ,  G01N2035/00524

    摘要： Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.

    摘要翻译： 提供了用于混合和净化材料（如流体材料）的样品处理单元。 样品处理单元通常包括被配置为容纳包含磁响应颗粒的样品和相对于容器处于基本固定位置的一个或多个磁体的容器。 样品处理单元还通常包括输送机构，其构造成将容器输送到与磁体磁连通的位置，例如使得当添加其它材料时，具有捕获的分析物的磁响应颗粒可以保留在容器内 到和/或从容器中取出。 此外，样品处理单元还通常包括旋转机构，其被配置为旋转容器，例如以实现设置在容器内的样品材料的混合。 还提供了相关的载体机构，样品处理站，系统和方法。

    Systems and methods for inducing infrared multiphoton dissociation with a hollow fiber waveguide
    87.
    发明授权
    Systems and methods for inducing infrared multiphoton dissociation with a hollow fiber waveguide 失效
    用中空纤维波导诱导红外多光子解离的系统和方法

    公开(公告)号：US06717137B2

    公开(公告)日：2004-04-06

    申请号：US10167269

    申请日：2002-06-11

    申请人： Steven A. Hofstadler ,  Jared J. Drader

    发明人： Steven A. Hofstadler ,  Jared J. Drader

    IPC分类号： H01J4904

    CPC分类号： H01J49/0059

    摘要： The present disclosure is related to improved systems and methods for inducing infrared multiphoton dissociation (IRMPD) of an ion. In an exemplary embodiment, the system includes an ion dissociation chamber and an infrared waveguide coupled to the ion dissociation chamber. The infrared waveguide may be positioned to receive infrared energy from an infrared energy source and direct the infrared energy towards ions in the ion dissociation chamber for the purpose of fragmenting the ions. The infrared waveguide can be made of a hollow fused silica body with an inner infrared reflective layer. The infrared waveguide may be flexible. A system may further include a focusing lens, an infrared transparent window and an aperture housing that has an orifice. The ion dissociation chamber may be an ion trap, an ion guide or an ion reservoir. In one embodiment, ions may be directed into an ion storage area of an ion dissociation chamber, the infrared energy is directed into the infrared waveguide which is aligned with the ion storage area and then infrared energy is delivering to the ions located within the ion storage area.

    摘要翻译： 本公开涉及用于诱导离子的红外多光子解离（IRMPD）的改进的系统和方法。 在示例性实施例中，系统包括离子解离室和耦合到离子解离室的红外波导。 红外波导可以定位成从红外能量源接收红外能量，并将红外能量引导到离子解离室中的离子，以分散离子。 红外波导可以由具有内部红外反射层的中空熔融石英体制成。 红外波导可以是柔性的。 系统还可以包括聚焦透镜，红外透明窗口和具有孔口的孔口壳体。 离子解离室可以是离子阱，离子导向器或离子储存器。在一个实施例中，离子可以被引导到离子解离室的离子存储区域中，红外能量被引导到与 离子存储区域然后红外能量传递到位于离子存储区域内的离子。

    Sample processing units, systems, and related methods
    89.
    发明授权
    Sample processing units, systems, and related methods 有权
    样品处理单元，系统和相关方法

    公开(公告)号：US08252599B2

    公开(公告)日：2012-08-28

    申请号：US13221608

    申请日：2011-08-30

    申请人： Steven A. Hofstadler ,  Jared J. Drader ,  Jose R. Gutierrez ,  Paul J. Gleason ,  Rex O. Bare ,  Robert D. Miller ,  Jeffrey C. Smith

    发明人： Steven A. Hofstadler ,  Jared J. Drader ,  Jose R. Gutierrez ,  Paul J. Gleason ,  Rex O. Bare ,  Robert D. Miller ,  Jeffrey C. Smith

    IPC分类号： C12M1/00 ,  G01N31/00 ,  G01N31/22 ,  G01N9/00

    CPC分类号： G01N1/10 ,  G01N1/02 ,  G01N35/0098 ,  G01N35/025 ,  G01N2035/00524

    摘要： Sample processing units useful for mixing and purifying materials, such as fluidic materials are provided. A sample processing unit typically includes a container configured to contain a sample comprising magnetically responsive particles, and one or more magnets that are in substantially fixed positions relative to the container. A sample processing unit also generally includes a conveyance mechanism configured to convey the container to and from a position that is within magnetic communication with the magnet, e.g., such that magnetically responsive particles with captured analytes can be retained within the container when other materials are added to and/or removed from the container. Further, a sample processing unit also typically includes a rotational mechanism that is configured to rotate the container, e.g., to effect mixing of sample materials disposed within the container. Related carrier mechanisms, sample processing stations, systems, and methods are also provided.

    摘要翻译： 提供了用于混合和净化材料（如流体材料）的样品处理单元。 样品处理单元通常包括被配置为容纳包含磁响应颗粒的样品和相对于容器处于基本固定位置的一个或多个磁体的容器。 样品处理单元还通常包括输送机构，其构造成将容器输送到与磁体磁连通的位置，例如使得当添加其它材料时，具有捕获的分析物的磁响应颗粒可以保留在容器内 到和/或从容器中取出。 此外，样品处理单元还通常包括旋转机构，其被配置为旋转容器，例如以实现设置在容器内的样品材料的混合。 还提供了相关的载体机构，样品处理站，系统和方法。