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公开(公告)号:US20220023360A1
公开(公告)日:2022-01-27
申请号:US17298263
申请日:2019-11-28
发明人: Eiji KOBATAKE , Toshihide KABUKI
IPC分类号: A61K35/747 , A23L33/195
摘要: A problem to be solved by the present invention is to provide a novel material increasing antimicrobial peptide production from epithelial cells and thereby having an infection-preventing effect. The present invention provides a composition for promoting antimicrobial peptide production containing lactic acid bacteria of the genus Lactobacillus as an active ingredient. The present invention also provides a composition for promoting antimicrobial peptide production containing a component derived from a Lactobacillus bacterial cell as an active ingredient. The present invention further provides a composition for promoting antimicrobial peptide production in which the component derived from a bacterial cell is one or more selected from the group consisting of an S-layer protein and a degradation product of the S-layer protein.
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公开(公告)号:US20170326209A1
公开(公告)日:2017-11-16
申请号:US15664450
申请日:2017-07-31
发明人: Aiko OHMACHI , Hiroaki MATSUYAMA, , Yoshikazu MORITA , Yuko ISHIDA , Takayuki NARA , Ken KATO , Atsushi SERIZAWA , Hiroshi UENO , Hiroshi URAZONO
CPC分类号: A61K38/465 , A23C9/1465 , A23C9/1512 , A23C9/1526 , A23L2/52 , A23L2/66 , A23V2002/00 , A61K38/1709 , C12Y301/27 , A23V2200/306
摘要: The invention relates to a drink includes angiogenin and/or angiogenin hydrolysate in an amount of more than 0.8 mg/1.00 ml and not more than 150 mg/100 ml, and cystatin and/or cystatin hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.006 to 1.7.
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公开(公告)号:US20170296632A1
公开(公告)日:2017-10-19
申请号:US15640977
申请日:2017-07-03
发明人: Aiko OHMACHI , Hiroaki MATSUYAMA , Yoshikazu MORITA , Yuko ISHIDA , Takayuki NARA , Ken KATO , Atsushi SERIZAWA , Hiroshi UENO , Hiroshi URAZONO
CPC分类号: A61K38/465 , A23C9/1465 , A23C9/1512 , A23C9/1526 , A23L2/52 , A23V2002/00 , A61K38/44 , C12Y111/01007 , C12Y301/27 , A23V2200/306
摘要: The invention relates to a drink includes angiogenin and/or angiogenin hydrolysate in an amount of more than 0.8 mg/100 ml and not more than 150 mg/100 ml, and lactoperoxidase and/or lactoperoxidase hydrolysate in the mass ratio to the angiogenin and/or angiogenin hydrolysate of 0.3 to 23.
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公开(公告)号:US20160303167A1
公开(公告)日:2016-10-20
申请号:US15133588
申请日:2016-04-20
发明人: Yoshihiko TAKANO , Takayuki NARA , Ken KATO , Yoshikazu MORITA
CPC分类号: A61K35/20 , A23K20/142 , A23K20/147 , A23K50/40 , A23L2/66 , A23L33/10 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K38/018 , A61K38/30 , A61K38/40 , A61K38/44 , A61K38/482 , C12Y111/01007 , A23V2200/326 , A23V2250/54 , A23V2250/542 , A23V2250/5424
摘要: It is an object of the present invention to provide a chondrogenesis promoter that is safe and exhibits a chondrogenesis-promoting effect by daily ingestion. It is also an object of the invention to provide a proteoglycan synthesis promoter that exhibits a proteoglycan synthesis-promoting effect by ingestion. Provided are a chondrogenesis promoter and a proteoglycan synthesis promoter each containing a milk-derived basic protein fraction as an active ingredient. Synthesis of proteoglycan and formation of a cartilage can be promoted by oral ingestion of the milk-derived basic protein fraction. A hydrolysate of the milk-derived basic protein fraction also has a similar chondrogenesis-promoting effect.
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公开(公告)号:US20160044949A1
公开(公告)日:2016-02-18
申请号:US14779647
申请日:2014-03-25
发明人: Hiroshi URAZONO , Yoshikazu MORITA , Noriko UEDA , Hiroshi UENO , Ken KATOH , Toshiya KOBAYASHI
IPC分类号: A23L1/305 , A23L1/0524 , A23L1/054 , A23L1/0534 , A23L2/66 , A23K1/16 , A61K35/20 , A61K47/36 , A61K47/42 , A61K47/24 , A61K47/38 , A61K38/44 , A61K38/40 , A61K38/30 , A23J1/20
CPC分类号: A23L33/19 , A23J1/20 , A23K20/147 , A23L2/66 , A23L29/10 , A23L29/20 , A23L29/231 , A23L29/262 , A23L29/269 , A23L29/27 , A23L29/275 , A23V2002/00 , A23V2250/02 , A23V2250/156 , A23V2250/1578 , A23V2250/18 , A23V2250/1842 , A23V2250/5036 , A23V2250/5056 , A23V2250/507 , A23V2250/5072 , A23V2250/5086 , A23V2250/51 , A23V2250/51082 , A23V2250/5114 , A23V2250/5118 , A23V2250/54246 , A23V2250/54248 , A23V2250/5425 , A23V2250/54252 , A23V2250/6416 , A23V2250/642 , A23V2250/70 , A61K35/20 , A61K38/018 , A61K38/30 , A61K38/40 , A61K38/44 , A61K47/24 , A61K47/36 , A61K47/38 , A61K47/42 , C12Y111/01007 , A23V2250/5028
摘要: The present invention provides a protein composition comprising a milk basic protein fraction; and at least one stabilizer selected from the group consisting of soybean polysaccharides, xanthan gum, pectin, gum arabic, gum ghatti, carrageenan, locust bean gum, sodium caseinate, lecithin, and carboxymethylcellulose. The protein composition significantly improves the heat resistance of the milk basic protein fraction. The present invention achieves heat treatment of a protein composition and food, beverage, feed, and pharmaceutical comprising such a protein composition at a temperature exceeding 90° C. without deactivation of the milk basic protein fraction.
摘要翻译: 本发明提供了包含乳碱性蛋白质级分的蛋白质组合物; 和选自大豆多糖,黄原胶,果胶,阿拉伯胶,加香胶,角叉菜胶,刺槐豆胶,酪蛋白酸钠,卵磷脂和羧甲基纤维素的至少一种稳定剂。 蛋白质组成显着提高了牛奶碱性蛋白质级分的耐热性。 本发明在超过90℃的温度下实现蛋白质组合物和包含这种蛋白质组合物的食品,饮料,饲料和药物的热处理,而不会使牛奶碱性蛋白质级分失活。
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公开(公告)号:US20160022771A1
公开(公告)日:2016-01-28
申请号:US14873622
申请日:2015-10-02
发明人: Ken KATOH , Hiroshi UENO , Yuko ONO , Noriko UEDA , Toshiya KOBAYASHI , Takahiro MORIYA , Yutaro OBARA
IPC分类号: A61K38/17 , A23K1/00 , A23K1/18 , A61K38/47 , A23L1/0562 , A61K8/64 , A61K8/66 , A61Q19/00 , A61K38/44 , A23L2/66
CPC分类号: A61K38/1709 , A23J3/343 , A23K10/12 , A23K10/28 , A23K20/142 , A23K20/147 , A23K50/40 , A23L2/66 , A23L29/281 , A23L33/18 , A23L33/19 , A23V2002/00 , A61K8/64 , A61K8/66 , A61K8/986 , A61K35/20 , A61K38/018 , A61K38/40 , A61K38/44 , A61K38/47 , A61K2800/40 , A61Q19/00 , C07K14/47 , C12N9/0065 , C12N9/22 , C12Y111/01007 , C12Y301/27 , Y02P60/875 , A23V2200/306 , A23V2250/54246 , A23V2250/54248 , A23V2250/5488 , A23V2250/55 , A23V2250/70
摘要: An object of the present invention is to provide a safety sensation-improving agent that can improve dulled peripheral sensations through daily ingestion or application to the skin. Another object of the present invention is to provide a sensation-improving food, beverage, feed, or cosmetics that can improve dulled peripheral sensations through oral ingestion or application to the skin. A sensation-improving agent containing a milk-derived protein and/or a hydrolysate therefrom as an active ingredient is provided. The milk-derived protein and/or the hydrolysate therefrom can be orally ingested or applied direct to the skin to improve dulled sensations, particularly peripheral sensations, and be formed into a sensation-improving food, beverage, feed, or cosmetics.
摘要翻译: 本发明的目的是提供一种安全感觉改善剂,其可以通过每日摄取或施用于皮肤来改善钝化的周围感觉。 本发明的另一个目的是提供一种改善感觉的食品,饮料,饲料或化妆品,其可以通过口服摄入或施用于皮肤来改善钝化的周围感觉。 提供了含有乳衍生蛋白质和/或其水解产物作为活性成分的感觉改善剂。 乳源性蛋白质和/或其水解物可以直接口服摄取或直接施用于皮肤,以改善昏暗的感觉,特别是周围的感觉,并形成感觉改善的食物,饮料,饲料或化妆品。
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公开(公告)号:US09173902B2
公开(公告)日:2015-11-03
申请号:US12530617
申请日:2008-03-10
申请人: Tatsuya Watanabe , Ken Kato , Hiroshi Ueno , Yuko Haruta , Noriko Ueda , Toshimitsu Yoshioka
发明人: Tatsuya Watanabe , Ken Kato , Hiroshi Ueno , Yuko Haruta , Noriko Ueda , Toshimitsu Yoshioka
IPC分类号: A61K8/00 , A61K35/20 , A23C9/152 , A23K1/16 , A23K1/18 , A23L1/305 , A23L2/52 , A61K8/64 , A61K38/01 , A61Q19/02
CPC分类号: A61K35/20 , A23C9/1526 , A23K20/147 , A23K50/40 , A23L2/52 , A23L33/18 , A23L33/19 , A61K8/64 , A61K38/00 , A61K38/018 , A61K2800/92 , A61Q19/02
摘要: A skin-whitening agent offering an excellent whitening effect and being effective in preventing and treating age spots, freckles, etc., where such skin-whitening agent contains as its effective ingredient a whey protein hydrolyzate characterized by a molecular weight distribution of 10 kDa or less, main peak of 200 Da to 3 kDa, APL (average peptide-chain length) of 2 to 8, free amino acid content of 20% or less, and antigenicity of one-ten thousandth of β-lactoglobulin or less, as well as a cosmetic, drink or food, feed, pharmaceutical preparation or other skin-whitening product containing such skin-whitening agent.
摘要翻译: 一种美白剂,其具有优异的美白效果,并有效预防和治疗老年斑,雀斑等,其中这样的皮肤增白剂作为其有效成分含有以10kDa分子量分布为特征的乳清蛋白水解产物,或 较少的主峰为200Da至3kDa,APL(平均肽链长度)为2至8,游离氨基酸含量为20%或更低,抗原性为万分之一以上的乳球蛋白或更少,为 以及化妆品,饮料或食品,饲料,药物制剂或含有这种皮肤增白剂的其它皮肤美白产品。
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公开(公告)号:US20150258184A1
公开(公告)日:2015-09-17
申请号:US14418276
申请日:2012-07-31
申请人: Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa
发明人: Aiko Ohmachi , Hiroaki Matsuyama , Yoshikazu Morita , Yuko Ishida , Takayuki Nara , Ken Kato , Atsushi Serizawa
CPC分类号: A61K38/57 , A23L33/17 , A23L33/18 , A23V2002/00 , A23V2200/00 , A61K38/01 , A61K38/22 , A61K38/465 , C12P21/06 , C12Y301/27 , A23V2200/306
摘要: The invention relates to a protein material includes angiogenin and/or angiogenin hydrolysate in an amount of 2 to 15 mg/100 mg, and cystatin and/or cystatin hydrolysate in the mass ratio to angiogenin and/or angiogenin hydrolysate of 0.003 to 0.6.
摘要翻译: 本发明涉及一种蛋白质材料,其包含2至15mg / 100mg量的血管生成素和/或血管生成素水解产物,以及与血管生成素和/或血管生成素水解产物的质量比为0.003至0.6的半胱氨酸蛋白酶抑制剂和/或半胱氨酸蛋白酶抑制剂水解产物。
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公开(公告)号:US08921342B2
公开(公告)日:2014-12-30
申请号:US12811744
申请日:2009-01-15
申请人: Tomoyuki Isogai , Yukio Kadooka , Reo Tanaka , Akira Tomizawa
发明人: Tomoyuki Isogai , Yukio Kadooka , Reo Tanaka , Akira Tomizawa
CPC分类号: A23L1/30 , A23K20/158 , A23L2/52 , A23L33/10 , A23L33/115 , A61K31/7032 , A61K35/20
摘要: Disclosed is a liver function-protecting agent which comprises a phospholipid as an active ingredient, and which can exhibit an excellent prophylactic and ameliorating effect on the deterioration in the liver function when ingested orally. Also disclosed is a liver function-protecting food, beverage or feed. The phospholipid is preferably one derived from milk or a milk material. Alternatively, the phospholipid may be used in the form of a phospholipid-containing composition prepared from milk or a milk material and containing the phospholipid in an amount of 10 wt % or more relative to the total solid content.
摘要翻译: 公开了一种肝功能保护剂,其包含磷脂作为活性成分,并且对于口服摄入时肝脏功能的退化具有优异的预防和改善作用。 还公开了肝功能保护食品,饮料或饲料。 磷脂最好是从牛奶或乳制品中得到的。 或者,磷脂可以以由乳或乳材料制备并含有相对于总固体含量为10重量%以上的量的磷脂的含磷脂组合物的形式使用。
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公开(公告)号:US20110319315A1
公开(公告)日:2011-12-29
申请号:US13132129
申请日:2009-12-14
申请人: Hisashi Naito , Susumu Miura
发明人: Hisashi Naito , Susumu Miura
CPC分类号: A23J3/343 , A23C9/1526 , A23C21/02 , A23K20/147 , A23K50/40 , A23L2/66 , A23L33/18 , A23V2002/00 , A61K38/018 , C12P21/06 , C12Y304/00 , A23V2250/54252 , A23V2200/316
摘要: A muscle-building agent comprising a whey protein hydrolyzate having a molecular weight distribution of 10 kDa or less, a main peak of 200 Da to 3 kDa, an average peptide length (APL) of 2 to 8, a free amino acid content of 20% or less, and antigenicity equal to or less than 1/100,000th of that of β-lactoglobulin is provided. The whey protein hydrolyzate is very safe, exhibits high transparency when dissolved in water, has low bitterness, can be used for an arbitrary product, and exhibits a muscle-building effect.
摘要翻译: 包含分子量分布为10kDa以下,主峰为200Da〜3kDa,平均肽长度(APL)为2〜8,游离氨基酸含量为20的乳清蛋白水解物的肌肉发育剂 %或更少,并且提供等于或小于β-乳球蛋白的抗原性的1/10000的抗原性。 乳清蛋白水解物非常安全,溶于水时具有高透明度,苦味低,可用于任意产品,具有肌肉发育作用。
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