-
公开(公告)号：US20130048512A1
公开(公告)日：2013-02-28
申请号：US13659189
申请日：2012-10-24
IPC分类号： G01N27/416 , G01N27/26
CPC分类号： G01N27/3274 , G01N33/49
摘要： The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 3.0 seconds or less, and/or having a clinically low Total System Error.
-
公开(公告)号：US08293904B2
公开(公告)日：2012-10-23
申请号：US13236838
申请日：2011-09-20
CPC分类号： G01N33/5306 , C07F15/002 , C07F15/0026 , C12Q1/004 , G01N33/5438 , G01N2458/30
摘要： The present invention provides novel osmium-based electrochemical species for the detection of wide variety of analytes using immunological techniques. The present invention also provides diagnostic kits and test sensors supporting electrode structures that can be used with the osmium-based electrochemical species. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal amplification desired to analyze analytes that may be present at low concentrations.
-
公开(公告)号：US08288544B2
公开(公告)日：2012-10-16
申请号：US10555138
申请日：2004-07-01
申请人： Eric R. Diebold , Mitali Ghoshal , David Z. Deng , Jane S.C. Tsai
发明人： Eric R. Diebold , Mitali Ghoshal , David Z. Deng , Jane S.C. Tsai
CPC分类号： G01N33/5306 , C07F15/002 , C07F15/0026 , C12Q1/004 , G01N33/5438 , G01N2458/30
摘要： The present invention provides novel osmium-based electrochemical species for the detection of wide variety of analytes using immunological techniques. The present invention also provides diagnostic kits and test sensors supporting electrode structures that can be used with the osmium-based electrochemical species. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal amplification desired to analyze analytes that may be present at low concentrations.
摘要翻译： 本发明提供用于使用免疫学技术检测多种分析物的新型锇基电化学物质。 本发明还提供了可与锇基电化学物质一起使用的支持电极结构的诊断试剂盒和测试传感器。 可以制造测试传感器以支持指数的电极阵列，其被设计为提供期望分析可能以低浓度存在的分析物的电信号放大的放大。
-
公开(公告)号：US08287703B2
公开(公告)日：2012-10-16
申请号：US12238023
申请日：2008-09-25
CPC分类号： C12Q1/001 , G01N27/3272 , G01N33/5438 , H05K1/0393 , H05K3/027 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156
摘要： An electrochemical biosensor with electrode elements that possess smooth, high-quality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds—without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.
摘要翻译： 具有电极元件的电化学生物传感器具有光滑，高质量的边缘。 这些光滑边缘限定电极，电极迹线和接触垫之间的间隙。 由于本发明实现了显着的边缘平滑度，所以间隙可以相当小，这在测试精度，速度和可以包装到单个生物传感器中的不同功能的数量方面提供显着的优点。 此外，本发明提供了一种新颖的生物传感器制造方法，其中可以以纳秒为单位形成本发明的生物传感器的整个电极图案，而不考虑电极图案的复杂性或必须烧蚀的导电材料的量 形成它们
-
5.发明申请SYSTEM AND METHOD FOR DETERMINING THE CONCENTRATION OF AN ANALYTE IN A SAMPLE FLUID 有权用于确定样品液中分析物浓度的系统和方法公开(公告)号：US20100170807A1
公开(公告)日：2010-07-08
申请号：US12650065
申请日：2009-12-30
IPC分类号： G01N27/26
CPC分类号： G01N27/3274 , G01N33/49
摘要： The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 2.0 seconds or less, and/or having a clinically low Total System Error.
摘要翻译： 本公开涉及使用电化学测试方法测量存在于生物流体中的分析物的量的各种方法。 公开了各种实施例，包括使用AC测试信号和在大约2.0秒或更短时间内具有总测试时间的测试和/或具有临床上低的总系统误差的测试。
-
公开(公告)号：US5260195A
公开(公告)日：1993-11-09
申请号：US638263
申请日：1991-01-03
申请人： Abol F. Azhar , Arthur M. Usmani , Anthony D. Burke , Jill DuBois-Bousamra , Eric R. Diebold , Myron C. Rapkin , Mark T. Skarstedt
发明人： Abol F. Azhar , Arthur M. Usmani , Anthony D. Burke , Jill DuBois-Bousamra , Eric R. Diebold , Myron C. Rapkin , Mark T. Skarstedt
CPC分类号： C12N11/08 , G01N33/525 , Y10S435/805
摘要： Non-aqueous, polymeric reagent film compositions for use with analytical test devices of the dry chemistry type are described. The film compositions are prepared from an organic solution of a copolymer formed by interaction of at least two monomers wherein(a) the first monomer is a hydroxylated acrylate of the general formula ##STR1## where R1 is hydrogen or, more preferably, methyl, and R2 is a hydroxyalkyl group having from 1 to 5 carbon atoms, and(b) the second monomer is a neutral acrylate of the general formula ##STR2## where R1 is hydrogen or, more preferably, methyl, and R3 is a substituted or unsubstituted alkyl group having from 1 to 8 carbon atoms.Preferably, a third monomer is also included which is an amine-containing acrylate of the general formula ##STR3## where R1 is hydrogen or, more preferably, methyl, and R4 is a substituted or unsubstituted aminoalkyl or glycidyl group having from 1 to 5 carbon atoms or a surfactant polyethylene glycol group having from 10 to 30 carbon atoms. The film further comprises at least one enzyme in powder form dispersed therein and, optionally, a chromogenic indicator. The film composition is especially useful for determining components in body fluids, for example, for detecting glucose in whole blood, by rapid techniques.
摘要翻译： 描述了用于干化学类型的分析测试装置的非水性聚合物试剂膜组合物。 膜组合物由通过至少两种单体的相互作用形成的共聚物的有机溶液制备，其中（a）第一单体是通式为“IMAGE”的羟基化丙烯酸酯，其中R 1是氢或更优选甲基，和 R2是具有1至5个碳原子的羟烷基，和（b）第二单体是通式为“IMAGE”的中性丙烯酸酯，其中R 1是氢或更优选甲基，R 3是取代或未取代的烷基 具有1至8个碳原子的基团。 优选地，还包括第三单体，其是通式为“IMAGE”的含胺丙烯酸酯，其中R 1是氢或更优选甲基，R 4是具有1至5个碳的取代或未取代的氨基烷基或缩水甘油基 原子或具有10至30个碳原子的表面活性剂聚乙二醇基团。 该膜还包含分散在其中的至少一种粉末形式的酶，以及任选的显色指示剂。 通过快速技术，该膜组合物特别可用于测定体液中的组分，例如用于检测全血中的葡萄糖。
-
公开(公告)号：USRE41309E1
公开(公告)日：2010-05-04
申请号：US10409721
申请日：2003-04-09
申请人： William F. Crismore , Nigel A. Surridge , Daniel R. McMinn , Richard J. Bodensteiner , Eric R. Diebold , R. Dale Delk , David W. Burke , Jiaxiong Jason Ho , Robert Kitchel Earl , Brian A. Heald
发明人： William F. Crismore , Nigel A. Surridge , Daniel R. McMinn , Richard J. Bodensteiner , Eric R. Diebold , R. Dale Delk , David W. Burke , Jiaxiong Jason Ho , Robert Kitchel Earl , Brian A. Heald
IPC分类号： G01N33/48
CPC分类号： C12Q1/001 , G01N27/3272 , G01N33/5438 , Y10S435/817
摘要： An electrochemical biosensor test strip with four new features. The test strip includes an indentation for tactile feel as to the location of the strips sample application port. The sample application port leads to a capillary test chamber, which includes a test reagent. The wet reagent includes from about 0.2% by weight to about 2% by weight polyethylene oxide from about 100 kilodaltons to about 900 kilodaltons mean molecular weight, which makes the dried reagent more hydrophilic and sturdier to strip processing steps, such as mechanical punching, and to mechanical manipulation by the test strip user. The roof of the capillary test chamber includes a transparent or translucent window which operates as a “fill to here” line, thereby identifying when enough test sample (a liquid sample, such as blood) has been added to the test chamber to accurately perform a test. The test strip may further include a notch located at the sample application port. The notch reduces a phenomenon called “dose hesitation”.
摘要翻译： 一种具有四个新特征的电化学生物传感器测试条。 测试条包括针对带样品应用端口的位置的触感的缩进。 样品应用端口通向包括测试试剂的毛细管测试室。 湿试剂包括约0.2重量％至约2重量％的聚环氧乙烷约100千道尔顿至约900千道尔顿的平均分子量，这使得干燥的试剂更具亲水性并且更坚固以进行剥离加工步骤，例如机械冲压，和 由测试用户进行机械操作。 毛细管测试室的屋顶包括透明或半透明的窗口，其作为“填充到这里”线，从而识别何时将足够的测试样品（液体样品，例如血液）添加到测试室以精确地执行 测试。 测试条还可以包括位于样品应用端口处的凹口。 缺口减少了称为“剂量犹豫”的现象。
-
公开(公告)号：US20120125788A1
公开(公告)日：2012-05-24
申请号：US13236838
申请日：2011-09-20
申请人： Eric R. DIEBOLD , Mitali GHOSHAL , David Z. DENG , Jane S.C. TSAI
发明人： Eric R. DIEBOLD , Mitali GHOSHAL , David Z. DENG , Jane S.C. TSAI
CPC分类号： G01N33/5306 , C07F15/002 , C07F15/0026 , C12Q1/004 , G01N33/5438 , G01N2458/30
摘要： The present invention provides novel osmium-based electrochemical species for the detection of wide variety of analytes using immunological techniques. The present invention also provides diagnostic kits and test sensors supporting electrode structures that can be used with the osmium-based electrochemical species. The test sensor can be fabricated to support interdigitated arrays of electrodes that have been designed to provide amplification of the electrical signal amplification desired to analyze analytes that may be present at low concentrations.
摘要翻译： 本发明提供用于使用免疫学技术检测多种分析物的新型锇基电化学物质。 本发明还提供了可与锇基电化学物质一起使用的支持电极结构的诊断试剂盒和测试传感器。 可以制造测试传感器以支持指数的电极阵列，其被设计为提供期望分析可能以低浓度存在的分析物的电信号放大的放大。
-
9.发明授权System and method for determining the concentration of an analyte in a sample fluid 有权用于确定样品流体中分析物浓度的系统和方法公开(公告)号：US08148164B2
公开(公告)日：2012-04-03
申请号：US12650065
申请日：2009-12-30
CPC分类号： G01N27/3274 , G01N33/49
摘要： The present disclosure relates to various methods for measuring the amount of an analyte present in a biological fluid using an electrochemical testing process. Various embodiments are disclosed, including the use of AC test signals and the performance of tests having a Total Test Time within about 2.0 seconds or less, and/or having a clinically low Total System Error.
摘要翻译： 本公开涉及使用电化学测试方法测量存在于生物流体中的分析物的量的各种方法。 公开了各种实施例，包括使用AC测试信号和在大约2.0秒或更短时间内具有总测试时间的测试和/或具有临床上低的总系统误差的测试。
-
公开(公告)号：US20090020502A1
公开(公告)日：2009-01-22
申请号：US12238023
申请日：2008-09-25
IPC分类号： H01B13/008
CPC分类号： C12Q1/001 , G01N27/3272 , G01N33/5438 , H05K1/0393 , H05K3/027 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156
摘要： An electrochemical biosensor with electrode elements that possess smooth, high-quality edges. These smooth edges define gaps between electrodes, electrode traces and contact pads. Due to the remarkable edge smoothness achieved with the present invention, the gaps can be quite small, which provides marked advantages in terms of test accuracy, speed and the number of different functionalities that can be packed into a single biosensor. Further, the present invention provides a novel biosensor production method in which entire electrode patterns for the inventive biosensors can be formed all at one, in nanoseconds—without regard to the complexity of the electrode patterns or the amount of conductive material that must be ablated to form them.
摘要翻译： 具有电极元件的电化学生物传感器具有光滑，高质量的边缘。 这些光滑边缘限定电极，电极迹线和接触垫之间的间隙。 由于本发明实现了显着的边缘平滑度，所以间隙可以相当小，这在测试精度，速度和可以包装到单个生物传感器中的不同功能的数量方面提供显着的优点。 此外，本发明提供了一种新颖的生物传感器制造方法，其中可以以纳秒为单位形成本发明的生物传感器的整个电极图案，而不考虑电极图案的复杂性或必须烧蚀的导电材料的量 形成它们
-
-
-
-
-
-
-
-
-
搜索结果
24 条记录 (耗时 0.029 秒)
