Method for monitoring glucose level
    6.
    发明授权
    Method for monitoring glucose level 失效
    监测血糖水平的方法

    公开(公告)号:US5056521A

    公开(公告)日:1991-10-15

    申请号:US374535

    申请日:1989-06-29

    CPC classification number: A61B10/0051 A61B5/14532

    Abstract: A sample of oral fluid is collected by an absorbent nonreactive collecting swab brought into contact with a favorable surface in the oral cavity. The fluid is interstitial transudate selectively collected from the vestibule region of the oral cavity at the junction of the superior labial mucous membrane and the superior gingivae between the upper canine teeth. The collecting swab is an open cell foam material with a fine (e.g., 0.3 mm diameter) cell size. The collecting swab is placed in a cylindrical concentrator and the fluid sample is squeezed through a small hole in the concentrator by pushing a plunger into the concentrator and squeezing the fluid from the collecting swab into a monitoring instrument located off site. A common electronic circuit in the instrument generates an electrical glucose representative readout for oral fluid or whole blood. A sheet of graph paper has rectangular coordinates one of which represents glucose level and the other which represents time of day. The first coordinate of the graph paper is mounted on a flat surface adjacent to a linear glucose level display. The user can record readings on the linear display by simply projecting such readings laterally on the graph to the applicable time of day and placing a mark on the graph. In the instrument, an enzyme electrode receives the sample from the concentrator. The electrode has a membrane that is wetted by a buffer solution when not in use.

    Abstract translation: 通过与口腔中的有利表面接触的吸收性非反应性收集拭子收集口腔液样品。 流体是间隔渗出物,其选择性地从口腔前庭区域在上部犬牙齿的上唇唇粘膜和上颌骨的交界处收集。 收集拭子是具有细(例如,0.3mm直径)细胞尺寸的开孔泡沫材料。 采集拭子放置在圆柱形浓缩器中,通过将柱塞推入聚光器并将流体从收集拭子挤压到位于场外的监测仪器中,将流体样品挤压在浓缩器中的小孔中。 仪器中的常见电子电路产生口服液体或全血的电葡萄糖代表性读数。 一张图纸具有直角坐标,其中一个表示葡萄糖水平,另一个表示一天中的时间。 图纸的第一坐标安装在与线性葡萄糖水平显示器相邻的平坦表面上。 用户可以通过简单地将图形上的读数横向投影到图表上的适用时间并在图形上放置标记来在线性显示屏上记录读数。 在仪器中,酶电极从浓缩器接收样品。 电极具有在不使用时被缓冲溶液润湿的膜。

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