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    Quantitative method and quantitative chip for target substance
    2.
    发明申请
    Quantitative method and quantitative chip for target substance 有权
    目标物质的定量方法和定量芯片

    公开(公告)号：US20060276975A1

    公开(公告)日：2006-12-07

    申请号：US10560311

    申请日：2004-04-09

    申请人： Takaaki Shimasaki ,  Akinori Yokogawa

    发明人： Takaaki Shimasaki ,  Akinori Yokogawa

    IPC分类号： G06F19/00

    CPC分类号： G01N33/49 ,  Y10T137/2224

    摘要： The present invention provides a quantitative measurement method and quantitative measurement chip which can perform quantitative measurement of a target substance in a short period of time. The invention provides a quantitative measurement method in which a three dimensional mesh structure material is formed, and quantitative measurements are taken of the target substance using a structure which contains a reagent that reacts with the target substance in the mesh. This method includes a contacting step in which a test specimen which includes the target substance is brought into contact with the structure; a detecting step which, in a process in which a substance whose quantity will increase or decrease by means of the reaction between the target substance and the reagent, detects the substance whose quantity is increasing or decreasing within the structure at a contact interface between the test specimen and the reagent; and a quantitative measurement step which performs quantitative measurement of the target substance based on the results of the detecting step. The mesh structure will allow at least the target substance to pass therethrough.

    摘要翻译： 本发明提供了能够在短时间内进行目标物质的定量测定的定量测定方法和定量测定用芯片。 本发明提供了一种定量测量方法，其中形成三维网格结构材料，并且使用包含与网格中的目标物质反应的试剂的结构对目标物质进行定量测量。 该方法包括使包含目标物质的试样与该结构体接触的接触工序; 检测步骤，其中通过所述目标物质与所述试剂之间的反应使其量增加或减少的物质的过程中，在所述测试中的接触界面处检测所述结构内的物质的数量增加或减少的物质 标本和试剂; 以及基于检测步骤的结果进行目标物质的定量测定的定量测定步骤。 网格结构将允许至少目标物质通过。

    ANALYTE COLLECTION CHIP
    3.
    发明申请
    ANALYTE COLLECTION CHIP 审中-公开
    分析器收集芯片

    公开(公告)号：US20090105614A1

    公开(公告)日：2009-04-23

    申请号：US12063561

    申请日：2006-08-15

    申请人： Shun Momose ,  Takaaki Shimasaki

    发明人： Shun Momose ,  Takaaki Shimasaki

    IPC分类号： A61B5/15 ,  A61M37/00 ,  A61M5/42

    CPC分类号： A61B5/15142 ,  A61B5/150022 ,  A61B5/150358 ,  A61B5/150412 ,  A61B5/150503 ,  A61B5/150969 ,  A61B5/15105 ,  A61B5/15107 ,  A61B5/15117 ,  A61B10/0045 ,  A61B17/205 ,  A61B2010/0006 ,  A61B2010/0009 ,  G01N33/491 ,  G01N2035/00158

    摘要： To provide a chip for collecting analyte from a living body. Specifically, the chip includes a thin plate-shaped main body, an analyte inlet portion, and a thin portion. Analyte is introduced into the analyte inlet portion, which is formed within the main body. The thin portion partitions the space forming the analyte inlet portion from the external space. According to the chip of the present invention, it is possible to eliminate the time for collecting analyte from a living body using a hypodermic syringe or the like, and placing the collected analyte into the chip. Also, the chip according to the present invention does not leave analyte remaining at the position from which the analyte was extracted, so after the test the position where the analyte was extracted from the living body is clean.

    摘要翻译： 提供用于从活体收集分析物的芯片。 具体地，芯片包括薄板状主体，​​分析物入口部分和薄部分。 将分析物引入到在主体内形成的分析物入口部分。 薄部分从外部空间分隔形成分析物入口部分的空间。 根据本发明的芯片，可以消除使用皮下注射器等从活体收集分析物的时间，并将收集的分析物放入芯片中。 此外，根据本发明的芯片不会将分析物残留在分析物被提取的位置，因此在测试之后，从生物体中提取分析物的位置是干净的。

    Microchannel and Microfluid Chip
    5.
    发明申请
    Microchannel and Microfluid Chip 审中-公开
    微通道和微流体芯片

    公开(公告)号：US20080317632A1

    公开(公告)日：2008-12-25

    申请号：US11885163

    申请日：2006-02-16

    申请人： Takaaki Shimasaki ,  Shun Momose

    发明人： Takaaki Shimasaki ,  Shun Momose

    IPC分类号： B01J19/00 ,  B01L11/00

    CPC分类号： B01L3/502723 ,  B01D19/0031 ,  B01L2200/0684 ,  B01L2300/0816 ,  B01L2400/086 ,  G01N2021/054 ,  G01N2035/1018

    摘要： There is provided a microchannel for allowing a liquid to flow. At least part of an inner surface of the microchannel is provided with a bubble trapping means for trapping any bubbles present in a liquid sample. This allows bubbles present in the liquid sample to be efficiently trapped even though only a tiny amount of sample may be used, regardless of the size of the microchannel. As a result, the flow of a fluid is not disrupted and thus measurement, detection, and so forth can be carried out accurately and quickly without hampering the measurement system.

    摘要翻译： 提供了用于允许液体流动的微通道。 微通道的内表面的至少一部分设置有用于捕获存在于液体样品中的任何气泡的气泡捕获装置。 这使得即使仅使用微量的样品，也不管微通道的尺寸如何，液体样品中存在的气泡被有效地捕获。 结果，流体的流动不会被破坏，因此可以准确而快速地进行测量，检测等，而不会妨碍测量系统。

    Quantitative measurement method and quantitative measurement chip for target substance
    6.
    发明授权
    Quantitative measurement method and quantitative measurement chip for target substance 有权
    目标物质的定量测量方法和定量测量芯片

    公开(公告)号：US07184894B2

    公开(公告)日：2007-02-27

    申请号：US10560311

    申请日：2004-04-09

    申请人： Takaaki Shimasaki ,  Akinori Yokogawa

    发明人： Takaaki Shimasaki ,  Akinori Yokogawa

    IPC分类号： G01N21/25

    CPC分类号： G01N33/49 ,  Y10T137/2224

    摘要： The present invention provides a quantitative measurement method and quantitative measurement chip which can perform quantitative measurement of a target substance in a short period of time. The invention provides a quantitative measurement method in which a three dimensional mesh structure material is formed, and quantitative measurements are taken of the target substance using a structure which contains a reagent that reacts with the target substance in the mesh. This method includes a contacting step in which a test specimen which includes the target substance is brought into contact with the structure; a detecting step which, in a process in which a substance whose quantity will increase or decrease by means of the reaction between the target substance and the reagent, detects the substance whose quantity is increasing or decreasing within the structure at a contact interface between the test specimen and the reagent; and a quantitative measurement step which performs quantitative measurement of the target substance based on the results of the detecting step. The mesh structure will allow at least the target substance to pass therethrough.

    摘要翻译： 本发明提供了能够在短时间内进行目标物质的定量测定的定量测定方法和定量测定用芯片。 本发明提供了一种定量测量方法，其中形成三维网格结构材料，并且使用包含与网格中的目标物质反应的试剂的结构对目标物质进行定量测量。 该方法包括使包含目标物质的试样与该结构体接触的接触工序; 检测步骤，其中通过所述目标物质与所述试剂之间的反应使其量增加或减少的物质的过程中，在所述测试中的接触界面处检测所述结构内的物质的数量增加或减少的物质 标本和试剂; 以及基于检测步骤的结果进行目标物质的定量测定的定量测定步骤。 网格结构将允许至少目标物质通过。

    Target recognition element and biosensor including the same
    7.
    发明授权
    Target recognition element and biosensor including the same 失效
    目标识别元件和包括其的生物传感器

    公开(公告)号：US07473549B2

    公开(公告)日：2009-01-06

    申请号：US10544875

    申请日：2004-02-05

    申请人： Atsushi Ikeda ,  Jun-ichi Kikuchi ,  Haruo Kotani ,  Yoko Hayashi ,  Takaaki Shimasaki

    发明人： Atsushi Ikeda ,  Jun-ichi Kikuchi ,  Haruo Kotani ,  Yoko Hayashi ,  Takaaki Shimasaki

    IPC分类号： C12M1/00 ,  G01N33/53 ,  G01N33/551 ,  G01N33/536 ,  G01N33/532

    CPC分类号： C12Q1/001 ,  G01N33/5438

    摘要： The present invention provides a target recognizing element wherein a receptor is fixed to an inclusion complex containing a mediator. The target recognizing element includes a first host molecule having hydrophilic groups and an inclusion site, a second host molecule having hydrophilic groups and an inclusion site, a receptor which is bonded to the hydrophilic groups of the second host molecule and which reacts with the target, and a guest molecule which is included by the inclusion site of the first host molecule and the inclusion site of the second host molecule and which transfers an electric charge generated by the reaction between the target and the receptor.

    摘要翻译： 本发明提供了一种目标识别元件，其中受体固定于含有介体的包合物。 靶识别元件包括具有亲水基团和包含位点的第一宿主分子，具有亲水基团和包含位点的第二宿主分子，与第二宿主分子的亲水基团键合并与靶物反应的受体， 以及由第一宿主分子的包含位点和第二宿主分子的包含位点所包含的并且转移由靶和受体之间的反应产生的电荷的客体分子。