Pharmaceutical composition for preventing / treating TRPV1 activity-related and inflammation-related diseases or conditions containing maillard peptide separated from well-aged traditional soy sauce as active ingredient
    1.
    发明授权
    Pharmaceutical composition for preventing / treating TRPV1 activity-related and inflammation-related diseases or conditions containing maillard peptide separated from well-aged traditional soy sauce as active ingredient 失效
    用于预防/治疗TRPV1活性相关的炎症相关疾病或病症的药物组合物含有从传统酱油中分离的美拉德肽作为活性成分

    公开(公告)号:US08653032B2

    公开(公告)日:2014-02-18

    申请号:US13508482

    申请日:2010-11-08

    CPC classification number: A61K38/168 A61K36/47

    Abstract: Disclosed is a pharmaceutical composition for preventing or treating TRPV1 activity-related or inflammation-related, diseases or conditions, containing a Maillard peptide separated from well-aged traditional soy sauce as an active ingredient. The Maillard peptide in the present invention functions both as a TRPV1 agonist and a TRPV1 antagonist, and further functions as a TRPV1 activity modulator. Therefore, the Maillard peptide can be used for preventing or treating TRPV1 activity-related diseases such as pain, neurological diseases, urgent defecation, inflammatory bowel disease, respiratory diseases, urinary incontinence, overactive bladder, neurogenic / allergic / inflammatory skin diseases, skin, eye or mucosal irritation, hyperacusis, tinnitus, vestibular hypersensitivity, heart disease, etc. The Maillard peptide can further inhibit COX-2 activity, and therefore can be effectively used for preventing or treating inflammation-related diseases or conditions such as rheumatic fever, influenza, cold, throat pain, headaches, toothaches, sprains, neuralgia, synovitis, rheumatoid arthritis, degenerative arthropathies, gout, ankylosing spondylitis, psoriasis, dermatitis, etc.

    Abstract translation: 公开了一种用于预防或治疗TRPV1活性相关或炎症相关疾病或病症的药物组合物,其含有以传统酱油作为有效成分分离的美拉德肽。 本发明中的美拉德肽作为TRPV1激动剂和TRPV1拮抗剂起作用,并且还起到TRPV1活性调节剂的作用。 因此,美拉德肽可用于预防或治疗TRPV1活动相关疾病如疼痛,神经系统疾病,紧急排便,炎性肠病,呼吸系统疾病,尿失禁,膀胱过度活动症,神经性/过敏性/炎性皮肤疾病,皮肤, 眼睛或粘膜刺激,腹泻,耳鸣,前庭超敏反应,心脏病等。美拉德肽可进一步抑制COX-2活性,因此可有效用于预防或治疗炎症相关疾病或病症如风湿热,流感 ,感冒,咽喉疼痛,头痛,牙痛,扭伤,神经痛,滑膜炎,类风湿关节炎,退行性关节病,痛风,强直性脊柱炎,牛皮癣,皮炎等。

    LAUNDRY TREATING APPARATUS
    2.
    发明申请
    LAUNDRY TREATING APPARATUS 审中-公开
    洗衣处理设备

    公开(公告)号:US20130342089A1

    公开(公告)日:2013-12-26

    申请号:US13768057

    申请日:2013-02-15

    Abstract: The present invention relates to a laundry treating apparatus that smoothly agitates laundry with as large space as possible for receiving laundry. The laundry treating apparatus includes: a rotatable drum that receives laundry, has open front and rear, and is formed to have a non-circular closed cross-section; a rotatable upper circular guide that is disposed with the rotational center higher than the rotational center of the drum and supports a portion having a uniform curvature at the upper portion of the drum; a rotatable lower circular guide that partially overlaps the upper circular guide, is disposed with the rotational center lower than the rotational center of the drum and supports a portion having a uniform curvature at the lower portion of the drum; a plurality of upper support rollers that supports the upper circular guide to be rotatable; and a plurality of lower support rollers that supports the lower circular guide to be rotatable.

    Abstract translation: 衣物处理装置技术领域本发明涉及一种衣物处理装置,其以尽可能大的空间顺畅地搅拌衣物以接收衣物。 衣物处理装置包括:接收衣物的可旋转滚筒,前后敞开,形成为非圆形封闭横截面; 旋转的上部圆形导向件,其旋转中心设置为高于滚筒的旋转中心,并且支撑在滚筒的上部具有均匀曲率的部分; 与上部圆形引导件部分重叠的可旋转的下部圆形导向件设置成旋转中心低于滚筒的旋转中心,并在滚筒的下部支撑具有均匀曲率的部分; 多个上支撑辊,其支撑所述上圆形导向件以可旋转; 以及多个下支撑辊,其支撑下圆形导向件以可旋转。

    LAUNDRY TREATING APPARATUS
    3.
    发明申请
    LAUNDRY TREATING APPARATUS 有权
    洗衣处理设备

    公开(公告)号:US20130334939A1

    公开(公告)日:2013-12-19

    申请号:US13768064

    申请日:2013-02-15

    Abstract: The present invention relates to a laundry treating apparatus that smoothly agitates laundry with as large space as possible for receiving laundry. The laundry treating apparatus includes: a rotatable drum that receives laundry, has open front and rear, and is formed to have a non-circular closed cross-section; a rotatable circular guide that supports a portion having a uniform curvature of the drum; and a drum guide that is disposed on the edge of the drum and seals the portion between the circular guide and the drum.

    Abstract translation: 衣物处理装置技术领域本发明涉及一种衣物处理装置,其以尽可能大的空间顺畅地搅拌衣物以接收衣物。 衣物处理装置包括:接收衣物的可旋转滚筒,前后敞开,形成为非圆形封闭横截面; 可旋转的圆形引导件,其支撑具有滚筒均匀曲率的部分; 以及鼓引导件,其设置在滚筒的边缘上并且密封圆形引导件和滚筒之间的部分。

    Pharmaceutical Composition for Preventing / Treating TRPV1 Activity-Related and Inflammation-Related Diseases or Conditions Containing Maillard Peptide Separated from Well-Aged Traditional Soy Sauce as Active Ingredient
    5.
    发明申请
    Pharmaceutical Composition for Preventing / Treating TRPV1 Activity-Related and Inflammation-Related Diseases or Conditions Containing Maillard Peptide Separated from Well-Aged Traditional Soy Sauce as Active Ingredient 失效
    用于预防/治疗TRPV1活性相关和炎症相关疾病或包含美味传统酱油作为活性成分分离的美拉德肽的病症的药物组合物

    公开(公告)号:US20120225808A1

    公开(公告)日:2012-09-06

    申请号:US13508482

    申请日:2010-11-08

    CPC classification number: A61K38/168 A61K36/47

    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating TRPV1 activity-related or inflammation-related, diseases or conditions, containing a Maillard peptide separated from well-aged traditional soy sauce as an active ingredient. The Maillard peptide according to the present invention functions both as a TRPV1 agonist and a TRPV1 antagonist, and thus functions as a TRPV1 activity modulator. Therefore, the present Maillard peptide can be used as a pharmaceutical composition for preventing or treating TRPV1 activity-related diseases such as pain, neurological diseases, urgent defecation, inflammatory bowel disease, respiratory diseases, urinary incontinence, overactive bladder, neurogenic/allergic/inflammatory skin diseases, skin, eye or mucosal irritation, hyperacusis, tinnitus, vestibular hypersensitivity, heart disease, etc. In addition, the Maillard peptide of the present invention can inhibit COX-2 activity, and therefore can be effectively used as a pharmaceutical composition for preventing or treating inflammation-related diseases or conditions such as rheumatic fever, influenza, cold, throat pain, headaches, toothaches, sprains, neuralgia, synovitis, rheumatoid arthritis, degenerative arthropathies, gout, ankylosing spondylitis, psoriasis, dermatitis, etc.

    Abstract translation: 本发明涉及一种用于预防或治疗TRPV1活性相关或炎症相关疾病或病症的药物组合物,其含有与传统酱油作为有效成分分离的美拉德肽。 根据本发明的美拉德肽既作为TRPV1激动剂又作为TRPV1拮抗剂起作用,因此起到TRPV1活性调节剂的作用。 因此,本发明的美拉德肽可用作预防或治疗TRPV1活性相关疾病如疼痛,神经系统疾病,紧急排便,炎性肠病,呼吸系统疾病,尿失禁,膀胱过度活动,神经源性/过敏性/炎症性的药物组合物 皮肤疾病,皮肤,眼睛或粘膜刺激,腹胀,耳鸣,前庭超敏反应,心脏病等。另外,本发明的美拉德肽可以抑制COX-2活性,因此可以有效地用作药物组合物 预防或治疗炎症相关疾病或病症如风湿热,流感,感冒,咽喉痛,头痛,牙痛,扭伤,神经痛,滑膜炎,类风湿性关节炎,退行性关节病,痛风,强直性脊柱炎,牛皮癣,皮炎等。

    LAUNDRY TREATING APPARATUS
    8.
    发明申请
    LAUNDRY TREATING APPARATUS 有权
    洗衣处理设备

    公开(公告)号:US20140053613A1

    公开(公告)日:2014-02-27

    申请号:US13768088

    申请日:2013-02-15

    Abstract: The present invention relates to a laundry treating apparatus that smoothly agitates laundry with as large space as possible for receiving laundry. The laundry treating apparatus includes: a rotatable drum that receives laundry, has open front and rear, and is formed to have a non-circular closed cross-section; a rotatable upper circular guide that is disposed with the rotational center higher than the rotational center of the drum and supports a portion having a uniform curvature at the upper portion of the drum; a rotatable lower circular guide that is disposed with the rotational center lower than the rotational center of the drum and supports a portion having a uniform curvature at the lower portion of the drum; and a driving mechanism rotating the drum by rotating the upper circular guide or the lower circular guide.

    Abstract translation: 衣物处理装置技术领域本发明涉及一种衣物处理装置,其以尽可能大的空间顺畅地搅拌衣物以接收衣物。 衣物处理装置包括:接收衣物的可旋转滚筒,前后敞开,形成为非圆形封闭横截面; 旋转的上部圆形导向件,其旋转中心设置为高于滚筒的旋转中心,并且支撑在滚筒的上部具有均匀曲率的部分; 一个可旋转的下圆形导向器,其设置有旋转中心低于滚筒的旋转中心,并支撑在滚筒下部具有均匀曲率的部分; 以及通过旋转上圆形导向件或下圆形导轨来旋转滚筒的驱动机构。

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