公开(公告)号：US5563169A

公开(公告)日：1996-10-08

申请号：US204420

申请日：1994-07-06

申请人： Akira Yoshida ,  Kozo Oda ,  Takashi Kasai ,  Teiichiro Koga ,  Kazuo Hasegawa

发明人： Akira Yoshida ,  Kozo Oda ,  Takashi Kasai ,  Teiichiro Koga ,  Kazuo Hasegawa

IPC分类号： A61K31/352 ,  A61K31/382 ,  A61P9/10 ,  C07D311/82 ,  C07D311/84 ,  C07D311/90 ,  C07D335/12 ,  C07D335/14 ,  C07D335/20 ,  C07D407/12 ,  A61K31/35

CPC分类号： C07D407/12 ,  C07D311/82 ,  C07D311/84 ,  C07D311/90 ,  C07D335/12 ,  C07D335/14 ,  C07D335/20

摘要： ConstitutionTricyclic heterocyclyl compounds having a general formula (I): ##STR1## wherein: R.sup.1 and R.sup.2 each represents H, a lower alkyl or lower alkoxy group, a halogen atom or halogeno-lower alkyl; R.sup.3 represents H or a lower alkyl group; R.sup.4 represents a substituted phenyl or naphthyl group; R.sub.5 represents H or a lower alkyl group; A represents a lower alkylene group; B represents an --O-- or --S-- group; and n is 0-1.EffectThe compounds have an excellent activity in the inhibition of acyl-CoA: cholesterol acyltransferase (ACAT) and are useful for the treatment and prophylaxis of atherosclerosis.

摘要翻译： PCT No.PCT / JP92 / 01164 Sec。 371日期：1994年7月6日 102（e）日期1994年7月6日PCT提交1992年9月11日PCT公布。 出版物WO93 / 03740 日期：1993年4月3日构造具有通式（I）的三环杂环基化合物：其中：R1和R2各自表示H，低级烷基或低级烷氧基，卤素原子或卤代低级烷基; R3代表H或低级烷基; R4表示取代的苯基或萘基; R5代表H或低级烷基; A表示低级亚烷基; B表示-O-或-S-基; n为0-1。 作用该化合物在酰基辅酶A：胆固醇酰基转移酶（ACAT）的抑制中具有优异的活性，可用于治疗和预防动脉粥样硬化。

公开(公告)号：US20100147063A1

公开(公告)日：2010-06-17

申请号：US12223250

申请日：2007-01-24

申请人： Hirohisa Suzuki ,  Eiji Akama ,  Kazuo Hasegawa

发明人： Hirohisa Suzuki ,  Eiji Akama ,  Kazuo Hasegawa

IPC分类号： B60C23/04

CPC分类号： B60C23/0408

摘要： The accuracy of a measurement value obtained by a tire pressure detection device is lowered by a centrifugal force and an inertial force during travel. A pressure sensor (30) displaces a diaphragm (20) in its vertical direction (32) according to the pressure. The pressure sensor (30) is arranged in a tire (2) with the vertical direction (32) directed to a direction parallel to a rotation axis (34) instead of the tire circumferential direction or radial direction. The pressure sensor (30) is mounted onto a substrate with the vertical direction (32) of its diaphragm (20) directed in parallel to the substrate surface and the substrate is bonded to a tread portion of the tire (2) and a wheel rim portion while adjusting the vertical direction (32) of the diaphragm (20) with the direction of the rotation axis (34).

摘要翻译： 由轮胎压力检测装置获得的测量值的精度通过离心力和行驶期间的惯性力而降低。 压力传感器（30）根据压力在其垂直方向（32）上移动隔膜（20）。 代替轮胎周向或径向，压力传感器（30）布置在轮胎（2）中，其中垂直方向（32）指向平行于旋转轴线（34）的方向。 压力传感器（30）安装在基板上，其隔膜（20）的垂直方向（32）平行于基板表面并且基板结合到轮胎（2）的胎面部分，轮缘 同时沿着旋转轴线（34）的方向调节隔膜（20）的垂直方向（32）。

公开(公告)号：US07332957B2

公开(公告)日：2008-02-19

申请号：US11462692

申请日：2006-08-04

申请人： Kazuo Hasegawa

发明人： Kazuo Hasegawa

IPC分类号： G05F1/10 ,  G05F3/02

CPC分类号： G05F1/575

摘要： A constant current circuit that generates a constant output current corresponding to an input voltage, comprises a differential amplifying unit to which the input voltage and a feedback voltage to be compared therewith are applied, the differential amplifying unit outputting a differential voltage, a first transistor with a first control electrode to which the differential voltage is applied, a first diode element that is connected to a power-supply side electrode of the first transistor, one or a plurality of second transistors that generates the output current, a feedback voltage conversion block that converts the duplicated current of the diode current flowing through the second transistor into the feedback voltage, and a constant current loading unit that is connected to a ground side electrode of the first transistor, the constant current loading unit making a voltage change in the ground side electrode follow a voltage change in the first control electrode.

摘要翻译： 产生对应于输入电压的恒定输出电流的恒流电路包括差分放大单元，其中施加输入电压和与其进行比较的反馈电压，差分放大单元输出差分电压，第一晶体管与 施加有差分电压的第一控制电极，连接到第一晶体管的电源侧电极的第一二极管元件，产生输出电流的一个或多个第二晶体管，反馈电压转换块， 将流过第二晶体管的二极管电流的复制电流转换为反馈电压，以及连接到第一晶体管的接地侧电极的恒流负载单元，在接地侧进行电压变化的恒定电流负载单元 电极跟随第一控制电极中的电压变化。

公开(公告)号：US07288978B2

公开(公告)日：2007-10-30

申请号：US11275808

申请日：2006-01-30

申请人： Hirohisa Suzuki ,  Kazuo Hasegawa ,  Eiji Akama

发明人： Hirohisa Suzuki ,  Kazuo Hasegawa ,  Eiji Akama

IPC分类号： H03H11/26

CPC分类号： H03K5/133 ,  H03K3/0315 ,  H03K2005/00026 ,  H03K2005/00156 ,  H03K2005/00202

摘要： In a delay circuit, when a first conductivity-type transistor (M6) becomes conductive on the basis of one level of its input signal, a first current path is formed through a source side transistor (M4), the first conductivity-type transistor (M6), and a second drive transistor (M9) between a source power line and a sink power line, and its output signal being the delayed inverse of the one level of the input signal is output from a connection point of another source side transistor (M5) and a sink side transistor (M11), and when a second conductivity-type transistor (M7) becomes conductive on the basis of the other level of the input signal, a second current path is formed through a first drive transistor (M3), the second conductivity-type transistor (M7), and another sink side transistor (M10), and the output signal being the delayed inverse of the other level of the input signal is output from the connection point.

摘要翻译： 在延迟电路中，当第一导电型晶体管（M 6）基于其输入信号的一个电平导通时，通过源极侧晶体管（M 4）形成第一电流路径，第一导电型 晶体管（M 6）和源极电源线和吸收电力线之间的第二驱动晶体管（M9），并且其输出信号是输入信号的一个电平的延迟的反相，从另一个的连接点输出 源极侧晶体管（M5）和漏极侧晶体管（M11），并且当第二导电型晶体管（M7）基于输入信号的其他电平导通时，形成第二电流路径 第一驱动晶体管（M 3），第二导电型晶体管（M7）和另一个漏极侧晶体管（M10），并且作为输入信号的另一个电平的延迟反相的输出信号从 连接点。

公开(公告)号：US07262650B2

公开(公告)日：2007-08-28

申请号：US11333547

申请日：2006-01-18

申请人： Hirohisa Suzuki ,  Kazuo Hasegawa ,  Eiji Akama

发明人： Hirohisa Suzuki ,  Kazuo Hasegawa ,  Eiji Akama

IPC分类号： H03L5/00

CPC分类号： H03K25/02

摘要： An amplitude adjusting circuit comprises a first current mirror where a variable current of a variable current source is copied into each of 1st-3rd transistors; a second current mirror where the variable current is copied into each of 11th-13th transistors; a third current mirror having 6th-7th transistors where a current through the 2nd transistor copied from the variable current flows through the 6th transistor; a fourth current mirror having 8th-9th transistors where a current through the 12th transistor copied from the variable current flows through the 8th transistor; an inverter that has 1st-2nd conductivity type transistors and produces an output signal corresponding to a current level of the 7th or 9th transistor; a fifth current mirror having 15th-14th transistors where a current through the 14th transistor copied from the 15th transistor's becomes a current sourced by the 7th transistor; and a sixth current mirror having 5th-4th transistors where a current through the 4th transistor copied from the 5th transistor's becomes a current sunk by the 9th transistor.

摘要翻译： 振幅调整电路包括第一电流镜，其中可变电流源的可变电流被复制到第一至第三晶体管的每一个中; 第二电流镜，其中可变电流被复制到第十一至第十三晶体管的每一个中; 具有第六晶体管的第三电流镜，其中从可变电流复制的通过第二晶体管的电流流过第六晶体管; 具有第八晶体管的第四电流镜，其中从可变电流复制的第十二晶体管的电流流过第八晶体管; 具有第1〜第2导电型晶体管并产生与第7或第9晶体管的电流电平对应的输出信号的反相器; 具有第十五至第十四晶体管的第五电流镜，其中从第十五晶体管复制的通过第十四晶体管的电流变为由第七晶体管产生的电流; 以及具有第五至第四晶体管的第六电流镜，其中通过第五晶体管复制的第四晶体管的电流由第九晶体管成为电流。

公开(公告)号：US20060188048A1

公开(公告)日：2006-08-24

申请号：US11275805

申请日：2006-01-30

申请人： Hirohisa Suzuki ,  Kazuo Hasegawa ,  Eiji Akama

发明人： Hirohisa Suzuki ,  Kazuo Hasegawa ,  Eiji Akama

IPC分类号： H04L7/02

CPC分类号： H04L7/033 ,  H03L7/0812 ,  H04L7/0066 ,  H04L7/0087 ,  H04L25/4904

摘要： A clock extracting circuit for receiving an encoded signal and for extracting a clock signal from the encoded signal. The circuit comprises an edge detector that detects rising and falling edges of the encoded signal and produces edge detection pulses indicating the edges being detected; a mask signal generator producing a mask signal which is inverted in response to the edge detection pulses, which are produced one for each period of the received encoded signal, on the basis of the edge detection pulses; a mask signal delay section delaying the mask signal by a delay time controllable and outputting the delayed mask signal; a clock generator producing the clock signal on the basis of edges of the delayed mask signal; and a delay controller that controls the delay time of the mask signal delay section so as to set a duty ratio of the produced clock signal to a predetermined value.

摘要翻译： 一种时钟提取电路，用于接收编码信号并从编码信号中提取时钟信号。 该电路包括边缘检测器，其检测编码信号的上升沿和下降沿，并产生指示所检测的边缘的边缘检测脉冲; 掩模信号发生器，其根据所述边缘检测脉冲产生响应于所述边缘检测脉冲反相的掩蔽信号，所述边缘检测脉冲是针对接收到的编码信号的每个周期产生的一个; 屏蔽信号延迟部分，将屏蔽信号延迟延迟时间可控并输出延迟的屏蔽信号; 基于延迟的掩码信号的边沿产生时钟信号的时钟发生器; 以及延迟控制器，其控制所述掩模信号延迟部分的延迟时间，以将所产生的时钟信号的占空比设定为预定值。

公开(公告)号：US06231890B1

公开(公告)日：2001-05-15

申请号：US09171631

申请日：1998-10-22

申请人： Mayumi Naito ,  Hiroshi Nakano ,  Kazuo Hasegawa ,  Toshiaki Nakajima ,  Ichiro Okudaira ,  Kenji Tsunoda

发明人： Mayumi Naito ,  Hiroshi Nakano ,  Kazuo Hasegawa ,  Toshiaki Nakajima ,  Ichiro Okudaira ,  Kenji Tsunoda

IPC分类号： A61K914

CPC分类号： A61K9/0095

摘要： A suspension of a sparingly water-soluble acidic drug, especially, a nonsteroidal anti-inflammatory analgesic agent, which is stable for a prolonged period of time and is highly dissolvable, and a process for simply and easily producing the suspension. This suspension has a pH value of 2 to 5 and comprises a sparingly water-soluble acidic drug whose average particle size ranges from 1 to 15 &mgr;m, a polyglycerol fatty acid ester, a water-soluble polyhydric alcohol and water, optionally, together with an inorganic powder having an average particle size of 1 to 15 &mgr;m. This process is characterized by carrying out pulverization and dispersion of a sparingly water-soluble acid drug, a polyglycerol fatty acid ester, a water-soluble polyhydric alcohol and water by means of a pulverizer comprising a main shaft adapted to rotate in a casing and a plurality of layshafts adapted to revolve in relationship interlocked with the rotation of the main shaft, each of the layshafts being fitted with a multiplicity of annular griding media.

摘要翻译： 微溶水性酸性药物，特别是长时间稳定且非常可溶性的非甾体抗炎止痛剂的悬浮液，以及简单且容易地制备悬浮液的方法。 该悬浮液的pH值为2〜5，并且包含平均粒径为1〜15μm的微溶水性酸性药物，聚甘油脂肪酸酯，水溶性多元醇和水，任选地与 平均粒径为1〜15μm的无机粉末。 该方法的特征在于通过粉碎机进行微水溶性酸性药物，聚甘油脂肪酸酯，水溶性多元醇和水的粉碎和分散，所述粉碎机包括适于在壳体内旋转的主轴和 多个副轴适于以与主轴的旋转互锁的关系旋转，每个副轴装配有多个环形磨盘。

公开(公告)号：US5781364A

公开(公告)日：1998-07-14

申请号：US794683

申请日：1997-02-03

申请人： Akira Hashimoto ,  Kazuo Hasegawa ,  Masao Sato

发明人： Akira Hashimoto ,  Kazuo Hasegawa ,  Masao Sato

IPC分类号： G11B21/02 ,  G11B5/016 ,  G11B5/55 ,  G11B7/085 ,  G11B21/04 ,  G11B21/08 ,  G11B21/10

CPC分类号： G11B5/5534 ,  G11B21/08 ,  G11B21/083 ,  G11B5/5521 ,  G11B5/5552 ,  G11B7/08582 ,  G11B21/046 ,  G11B5/016

摘要： This invention provides a small-sized and easy assembling head positioning apparatus having a coarse moving mechanism and fine moving mechanism, by which the desired fine moving accuracy is easy to attain. A head positioning apparatus has a first stepping motor, a lead screw, and a cylindrical rack for coarse moving. The cylindrical rack is formed by rotating a rack around the axis of the lead screw and is provided with the lead screw. The head positioning apparatus has a second stepping notor and gears for reducing the speed of the rotation of the second stepping motor for fine moving means, and fine moving is carried out by moving the cylindrical rack by the gear. The lead screw is provided so that the first stepping motor could be moved in a X1, X2 direction in the fixed moving range.

摘要翻译： 本发明提供了一种具有粗移动机构和精细移动机构的小型且易于组装的头部定位装置，通过该机构可以容易地获得期望的精细移动精度。 头定位装置具有第一步进电机，导螺杆和用于粗动的圆柱形齿条。 圆柱形齿条通过围绕导螺杆的轴线旋转齿条并且设置有导螺杆而形成。 头部定位装置具有第二步进机构和用于降低用于微细移动装置的第二步进电机的旋转速度的齿轮，并且通过齿轮移动圆柱形齿条来进行微细移动。 提供导螺杆，使得第一步进电机能够在固定移动范围内沿X1，X2方向移动。

公开(公告)号：US5698576A

公开(公告)日：1997-12-16

申请号：US755290

申请日：1996-11-22

申请人： Atsusuke Terada ,  Kazuyuki Wachi ,  Hachio Miyazawa ,  Yoshio Iizuka ,  Kazuo Hasegawa ,  Keiichi Tabata

发明人： Atsusuke Terada ,  Kazuyuki Wachi ,  Hachio Miyazawa ,  Yoshio Iizuka ,  Kazuo Hasegawa ,  Keiichi Tabata

IPC分类号： A61K31/415 ,  A61K31/4188 ,  A61K31/422 ,  A61K31/4439 ,  A61K31/4725 ,  C07D487/04 ,  C07D235/00

CPC分类号： C07D487/04 ,  A61K31/415 ,  A61K31/4188 ,  A61K31/422 ,  A61K31/4439 ,  A61K31/4725

摘要： Described herein are compounds of formula (I): ##STR1## �in which: R.sup.1 and R.sup.2 are hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, aralkyl, arylalkenyl, aryl, aromatic heterocyclic, cyano or halogen; R.sup.3 is hydrogen, optionally substituted alkyl, aralkyl or acyl; R.sup.4 and R.sup.5 are hydrogen, optionally substituted alkyl, cycloalkyl, alkenyl, aralkyl, arylalkenyl, aryl or aromatic heterocyclic!; and pharmaceutically acceptable salts thereof are analgesics and anti-inflammatory agents as well having anti-ulcer and 5-lipoxygenase inhibitory activities.

摘要翻译： 本文描述的是式（I）的化合物：其中：R 1和R 2是氢，任选取代的烷基，环烷基，烯基，芳烷基，芳基烯基，芳基，芳族杂环，氰基或卤素; R3是氢，任选取代的烷基，芳烷基或酰基; R 4和R 5是氢，任选取代的烷基，环烷基，烯基，芳烷基，芳基烯基，芳基或芳族杂环]; 及其药学上可接受的盐是具有抗溃疡和5-脂氧合酶抑制活性的止痛剂和抗炎剂。

公开(公告)号：US5519553A

公开(公告)日：1996-05-21

申请号：US157898

申请日：1993-11-24

申请人： Akira Hashimoto ,  Kazuo Hasegawa ,  Masao Sato

发明人： Akira Hashimoto ,  Kazuo Hasegawa ,  Masao Sato

IPC分类号： G11B21/02 ,  G11B5/016 ,  G11B5/55 ,  G11B7/085 ,  G11B21/04 ,  G11B21/08 ,  G11B21/10

CPC分类号： G11B5/5534 ,  G11B21/08 ,  G11B21/083 ,  G11B5/5521 ,  G11B5/5552 ,  G11B7/08582 ,  G11B21/046 ,  G11B5/016

摘要： This invention provides a small-sized and easy-assembling head positioning apparatus having a coarse moving mechanism and fine moving mechanism, by which the desired fine moving accuracy is easy to attain. A head positioning apparatus has a first stepping motor, a lead screw, and a cylindrical rack for coarse moving. The cylindrical rack is formed by rotating a rack around the axis of the lead screw and is provided with the lead screw. The head positioning apparatus has a second stepping motor and gears for reducing the speed of the rotation of the second stepping motor for fine moving means, and fine moving is carried out by moving the cylindrical rack by the gear. The lead screw is provided so that the first stepping motor could be moved in a X1, X2 direction in the fixed moving range.

摘要翻译： 本发明提供一种具有粗移动机构和精细移动机构的小型且易于组装的头部定位装置，由此可以容易地获得所需的精细移动精度。 头定位装置具有第一步进电机，导螺杆和用于粗动的圆柱形齿条。 圆柱形齿条通过围绕导螺杆的轴线旋转齿条并且设置有导螺杆而形成。 头部定位装置具有第二步进电机和用于降低用于微细移动装置的第二步进电机的旋转速度的齿轮，并且通过齿轮移动圆柱形齿条来进行微细移动。 提供导螺杆，使得第一步进电机能够在固定移动范围内沿X1，X2方向移动。