公开(公告)号：US20190240119A1

公开(公告)日：2019-08-08

申请号：US16316802

申请日：2017-07-17

申请人： BASF SE

发明人： KATHRIN MEYER-BOEHM ,  Thrandur HELGASON ,  Raajvinder SINGH ,  Walter DOBLER ,  Peter SCHORDING ,  Christof Wilhelm WIGBERS ,  Karl KOLTER ,  Stefan BRUHNS ,  Wolf PELLETIER ,  Daniel WAGNER

IPC分类号： A61K8/02 ,  A23L33/155 ,  A23K20/174 ,  A23P10/20 ,  A61K8/37 ,  A61K8/35 ,  A61K8/67 ,  A61K8/34 ,  A61K31/12 ,  A61K31/122 ,  A61K31/355 ,  A61K31/05 ,  A61K31/375 ,  A61K9/14

CPC分类号： A61K8/022 ,  A23K20/174 ,  A23L33/15 ,  A23L33/155 ,  A23P10/20 ,  A23V2002/00 ,  A61K8/31 ,  A61K8/347 ,  A61K8/35 ,  A61K8/37 ,  A61K8/67 ,  A61K8/676 ,  A61K8/678 ,  A61K9/14 ,  A61K31/015 ,  A61K31/05 ,  A61K31/12 ,  A61K31/122 ,  A61K31/235 ,  A61K31/355 ,  A61K31/375 ,  A61K45/06 ,  A61K2800/10 ,  A61K2800/412 ,  A61K2800/52 ,  A61K2800/522 ,  A61Q19/00 ,  A23V2250/211 ,  A23V2250/712 ,  A61K2300/00

摘要： The present invention relates to a pulverulent vitamin formulation in which the vitamin essentially has a particle size of less than 0.7 μm and which comprises an effective amount of propyl gallate, and also to processes for producing this formulation, and to formulations obtainable by these processes and to the use thereof as animal feed, food, food supplement, personal care product or pharmaceutical composition. The formulations of the invention have improved stability compared to the prior art.

公开(公告)号：US20170275232A1

公开(公告)日：2017-09-28

申请号：US15505803

申请日：2015-08-25

申请人： BASF SE

发明人： Christof Wilhelm WIGBERS ,  Wolfgang MAEGERLEIN ,  Thomas KRUG ,  Johann-Peter MELDER ,  Thomas HEIDEMANN ,  Bernd STEIN

IPC分类号： C07C209/48 ,  B01J23/78 ,  B01J35/00 ,  B01J23/75 ,  B01J37/18

CPC分类号： C07C209/48 ,  B01J23/75 ,  B01J23/78 ,  B01J35/0006 ,  B01J35/002 ,  B01J37/18 ,  C07C2523/75 ,  Y02P20/582 ,  C07C211/11 ,  C07C211/09 ,  C07C211/12 ,  C07C211/18

摘要： The invention relates to a process for preparing primary amines, which comprises hydrogenating at least one nitrile in an apparatus (V1) in the presence of an unsupported cobalt catalyst to obtain at least one primary amine, with recurrent or continuous addition of at least one compound (I) to the apparatus (V1), said compound (I) comprising at least one component selected from alkali metal, alkaline earth metal and rare earth metal.

公开(公告)号：US20170362164A1

公开(公告)日：2017-12-21

申请号：US15534856

申请日：2015-12-01

申请人： BASF SE

发明人： Christof Wilhelm WIGBERS ,  Wolfgang MÄGERLEIN ,  Thomas KRUG ,  Johann-Peter MELDER

IPC分类号： C07C213/02 ,  B01J23/75 ,  B01J23/72 ,  B01J23/28 ,  B01J23/14 ,  B01J23/04 ,  B01J21/06 ,  B01J23/755 ,  B01J21/04

CPC分类号： C07C213/02 ,  B01J21/04 ,  B01J21/066 ,  B01J23/04 ,  B01J23/14 ,  B01J23/28 ,  B01J23/72 ,  B01J23/75 ,  B01J23/755 ,  C08G65/2621 ,  C08G65/2648 ,  C08G65/2696 ,  Y02P20/582

摘要： A process for producing a polyetheramine by reacting a polyether alcohol, previously synthesized in the presence of a basic potassium or sodium compound as catalyst, with ammonia in the presence of hydrogen and a catalyst in one reactor or a plurality of reactors, wherein the employed polyether alcohol when previously synthesized in the presence of a basic potassium compound as catalyst has a content of potassium ions of less than 50 wppm and when previously synthesized in the presence of a basic sodium compound as catalyst has a content of sodium ions of less than 50 wppm.

公开(公告)号：US20150329477A1

公开(公告)日：2015-11-19

申请号：US14653094

申请日：2013-12-18

申请人： BASF SE

发明人： Ortmund LANG ,  Norbert ASPRION ,  Axel BINDER ,  Bernd METZEN ,  Christof Wilhelm WIGBERS ,  Petr KUBANEK ,  Thomas STEINHILBER

IPC分类号： C07C231/24 ,  B01D3/42 ,  B01D3/06

CPC分类号： C07C231/24 ,  B01D3/06 ,  B01D3/42 ,  C07C231/02 ,  C07C233/05

摘要： What is proposed is a continuous process for discharging a solid, salt-containing phase comprising alkali metal acetates and/or alkaline earth metal acetates from the product mixture from the preparation of N,N-dimethylacetamide (DMAC) by reaction of methyl acetate (MeOAc) with dimethylamine (DMA) in the presence of a catalyst comprising N,N-dimethylacetamide (DMAC), methyl acetate (MeOAc), dimethylamine (DMA) and a catalyst, having the following process steps: level-regulated feeding of the product mixture as feed stream into an evaporation vessel of a forced circulation evaporator, flash evaporation of volatile components of the product mixture in the forced circulation evaporator to form a vapor phase comprising N,N-dimethylacetamide (DMAC) and precipitation of a solid, salt-containing phase comprising alkali metal acetates and/or alkaline earth metal acetates, recycling of the volatile components of the product mixture obtained after the flash evaporation, removal of a vapor phase comprising N,N-dimethylacetamide (DMAC) from the evaporation vessel as output stream, concentration of the solid, salt-containing phase comprising alkali metal acetates and/or alkaline earth metal acetates in the forced circulation evaporation circuit of the forced circulation evaporator, discharge of a substream comprising the solid, salt-containing phase comprising alkali metal acetates and/or alkaline earth metal acetates from the forced circulation evaporation circuit of the forced circulation evaporator, solid/liquid separation of the discharged substream in at least one separation apparatus into a solid, salt-containing phase comprising alkali metal acetates and/or alkaline earth metal acetates and a liquid phase, recycling of the liquid phase obtained after the solid/liquid separation into the forced circulation evaporation circuit as recycle stream, wherein the recycling of the volatile components of the product mixture obtained after the flash evaporation and of the solid, salt-containing phase comprising alkali metal acetates and/or alkaline earth metal acetates into the evaporation vessel is effected via an introduction section which ends within a range from 30 cm above the level surface to 20 cm below the level surface of the fill level of the evaporation vessel.