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公开(公告)号:US09285382B2
公开(公告)日:2016-03-15
申请号:US13747834
申请日:2013-01-23
Applicant: Beckman Coulter, Inc.
Inventor: Brian D. Wilson , Matthew S. Davis , Matthew D. Erickson , Alan N. Johnson , Garrick A. Maurer , Daniel R. Schmidt , Joshua D. Wiltsie
IPC: B01L3/00 , G01N35/00 , G01N35/04 , G01N35/10 , C12P19/34 , B01L7/00 , C12Q3/00 , G05B13/02 , G01F23/24 , G01F23/26 , G06F19/10 , C12M1/34 , C12Q1/68 , G01N1/38 , G01N1/31 , B01L3/02
CPC classification number: G01N35/04 , B01L3/021 , B01L3/0275 , B01L3/50825 , B01L3/5085 , B01L3/50851 , B01L3/52 , B01L3/545 , B01L7/52 , B01L2200/025 , B01L2200/0642 , B01L2200/0668 , B01L2200/12 , B01L2200/147 , B01L2300/021 , B01L2300/022 , B01L2300/024 , B01L2300/042 , B01L2300/044 , B01L2300/045 , B01L2300/046 , B01L2300/0654 , B01L2300/0851 , B01L2300/123 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B01L2400/043 , C12M41/12 , C12P19/34 , C12Q1/68 , C12Q1/686 , C12Q3/00 , G01F23/24 , G01F23/26 , G01N1/31 , G01N1/38 , G01N35/00732 , G01N35/0092 , G01N35/0098 , G01N35/1002 , G01N35/1011 , G01N35/1016 , G01N35/1081 , G01N2035/00435 , G01N2035/00752 , G01N2035/00851 , G01N2035/0413 , G01N2035/0415 , G01N2035/0436 , G01N2035/0465 , G01N2035/0475 , G01N2035/1013 , G01N2035/1025 , G01N2035/1048 , G01N2035/1051 , G01N2035/1076 , G05B13/02 , G05B13/0205 , G06F19/10 , Y10T436/113332
Abstract: Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.
Abstract translation: 公开了用于处理和分析样品的系统和方法。 该系统可以使用可在不同处理位置处理的测定盒来处理样品,例如生物流体。 在某些情况下,该系统可用于PCR处理。 不同的处理位置可以包括可以准备样品的准备位置和可以分析样品的分析位置。 为了帮助准备样品,系统还可以包括可以包括加工车道的多个处理站。 在样品分析期间,在某些情况下,可以使用热循环仪模块和适当的光学检测系统来检测样品中某些核酸序列的存在或不存在。 该系统可用于准确快速地处理样品。
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公开(公告)号:US09140715B2
公开(公告)日:2015-09-22
申请号:US13747952
申请日:2013-01-23
Applicant: Beckman Coulter, Inc.
Inventor: Brian D. Wilson , Matthew S. Davis , Alan N. Johnson , Garrick A. Maurer
IPC: C12P19/34 , G01N35/04 , G01N35/10 , G01N35/00 , B01L3/00 , B01L7/00 , C12Q3/00 , G05B13/02 , G01F23/24 , G01F23/26 , G06F19/10 , C12M1/34 , C12Q1/68 , G01N1/38 , G01N1/31 , B01L3/02
CPC classification number: G01N35/04 , B01L3/021 , B01L3/0275 , B01L3/50825 , B01L3/5085 , B01L3/50851 , B01L3/52 , B01L3/545 , B01L7/52 , B01L2200/025 , B01L2200/0642 , B01L2200/0668 , B01L2200/12 , B01L2200/147 , B01L2300/021 , B01L2300/022 , B01L2300/024 , B01L2300/042 , B01L2300/044 , B01L2300/045 , B01L2300/046 , B01L2300/0654 , B01L2300/0851 , B01L2300/123 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B01L2400/043 , C12M41/12 , C12P19/34 , C12Q1/68 , C12Q1/686 , C12Q3/00 , G01F23/24 , G01F23/26 , G01N1/31 , G01N1/38 , G01N35/00732 , G01N35/0092 , G01N35/0098 , G01N35/1002 , G01N35/1011 , G01N35/1016 , G01N35/1081 , G01N2035/00435 , G01N2035/00752 , G01N2035/00851 , G01N2035/0413 , G01N2035/0415 , G01N2035/0436 , G01N2035/0465 , G01N2035/0475 , G01N2035/1013 , G01N2035/1025 , G01N2035/1048 , G01N2035/1051 , G01N2035/1076 , G05B13/02 , G05B13/0205 , G06F19/10 , Y10T436/113332
Abstract: Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.
Abstract translation: 公开了用于处理和分析样品的系统和方法。 该系统可以使用可在不同处理位置处理的测定盒来处理样品,例如生物流体。 在某些情况下,该系统可用于PCR处理。 不同的处理位置可以包括可以准备样品的准备位置和可以分析样品的分析位置。 为了帮助准备样品,系统还可以包括可以包括加工车道的多个处理站。 在样品分析期间,在某些情况下,热循环仪模块和适当的光学检测系统可用于检测样品中某些核酸序列的存在或不存在。 该系统可用于准确快速地处理样品。
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公开(公告)号:US12145146B2
公开(公告)日:2024-11-19
申请号:US18057652
申请日:2022-11-21
Applicant: Beckman Coulter, Inc.
Inventor: Matthew S. Davis , Ronald Douglas Johnson , Mark A. Nierzwick , Craig A. Hudson , Charles M. Neese , Mark F. Sauerburger , John S. Snider
Abstract: Embodiments of lab automation workstations are disclosed in which the pod that performs pipetting operations is integrated with pipette tip-loading functionality. To generate the necessary tip-loading force, a dual drive system is used that is symmetric about the Y-axis to allow for offset or partial tip box loads by dynamically centering the drive force (e.g., the tip-loading force) over the reaction load. This minimizes the need for oversized linear motion components while still allowing for the generation of high tip-loading forces needed to properly load a large number of pipette tips simultaneously.
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公开(公告)号:US20230358773A1
公开(公告)日:2023-11-09
申请号:US18355119
申请日:2023-07-19
Applicant: Beckman Coulter, Inc.
Inventor: Matthew S. Davis , Rachel Ellen Moschell , Peter Robert Nei , John S. Snider
IPC: G01N35/00
CPC classification number: G01N35/0092 , G01N35/00732 , G01N35/00871 , G01N2035/00881 , G01N2035/0091 , G01N2035/0094
Abstract: A server stores a set of laboratory applications to process batches of samples. The server receives, from a first lab administrator, a selection of a subset of the laboratory applications to process the batches of samples and an admin configuration for a laboratory application in the subset. The server receives configuration(s) of batch(es) to be used for running at least a portion of the subset of laboratory applications configured according to the admin configuration. The server receives, from a first scientific device, a request to run a laboratory application form the first subset to process a batch. The server provides the laboratory application(s) that are capable of being executed using the first scientific device. The server receives, from the first scientific device, a selected laboratory application. The server transmits, to the first scientific device, a signal for executing a first part of the selected laboratory application.
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公开(公告)号:US11872552B2
公开(公告)日:2024-01-16
申请号:US17271278
申请日:2019-08-30
Applicant: Beckman Coulter, Inc.
Inventor: Charles Neese , Matthew S. Davis
CPC classification number: B01L3/0224 , B01L2200/023 , B01L2200/025 , B01L2300/0681 , B01L2300/087 , B01L2400/0478
Abstract: A pipetting device is disclosed. The pipetting device can include a piston with a stepped profile. The piston can be inserted into a barrel and can have at least two seal elements. The pipetting device can operate in a low volume dispense mode and a high volume dispense mode. The pipetting device can allow for high volumes of liquids to be transferred and also provide for the ability to transfer low volumes of liquids with high precision and accuracy without the need for two or more separate pipettor devices.
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公开(公告)号:US11534750B2
公开(公告)日:2022-12-27
申请号:US16477823
申请日:2018-01-09
Applicant: Beckman Coulter, Inc.
Inventor: Matthew S. Davis , Ronald Douglas Johnson , Mark A. Nierzwick , Craig A. Hudson , Charles M. Neese , Mark F. Sauerburger , John S. Snider
Abstract: Embodiments of lab automation workstations are disclosed in which the pod that performs pipetting operations is integrated with pipette tip-loading functionality. To generate the necessary tip-loading force, a dual drive system is used that is symmetric about the Y-axis to allow for offset or partial tip box loads by dynamically centering the drive force (e.g., the tip-loading force) over the reaction load. This minimizes the need for oversized linear motion components while still allowing for the generation of high tip-loading forces needed to properly load a large number of pipette tips simultaneously.
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公开(公告)号:US20220341954A1
公开(公告)日:2022-10-27
申请号:US17787216
申请日:2020-12-16
Applicant: Beckman Coulter, Inc.
Inventor: Matthew S. Davis , Rachel Ellen Moschell , Peter Robert Nei , John S. Snider
IPC: G01N35/00
Abstract: A server stores a set of laboratory applications to process batches of samples. The server receives, from a first lab administrator, a selection of a subset of the laboratory applications to process the batches of samples and an admin configuration for a laboratory application in the subset. The server receives configuration(s) of batch(es) to be used for running at least a portion of the subset of laboratory applications configured according to the admin configuration. The server receives, from a first scientific device, a request to run a laboratory application form the first subset to process a batch. The server provides the laboratory application(s) that are capable of being executed using the first scientific device. The server receives, from the first scientific device, a selected laboratory application. The server transmits, to the first scientific device, a signal for executing a first part of the selected laboratory application.
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公开(公告)号:US20230020118A1
公开(公告)日:2023-01-19
申请号:US17787418
申请日:2020-12-18
Applicant: Beckman Coulter, Inc.
Inventor: Matthew S. Davis , Kristina K. Lu , Rachel Ellen Moschell , Peter Robert Nei , Mark F. Sauerburger , Zachary M. Smith , John S. Snider , Jason L. Springston
Abstract: A reaction vessel comprises a lower chamber with a first volume, and an upper chamber with a second volume greater than the first volume. A thermocycling system for heating the reaction vessel includes a lower heating zone to heat the lower chamber, an upper heating zone to heat the upper chamber, and a lid heater to heat an opening of the upper chamber. A method comprises loading a sample into a lower chamber of a reaction vessel, thermocycling the lower chamber using a lower heating zone of the thermo cycler, combining an additive into the sample to produce a combination filling the lower chamber and at least partially filling an upper chamber of the reaction vessel, and incubating the upper and lower chambers using the lower heating zone and an upper heating zone. The lower and upper chambers can have different wall thicknesses to facilitate heat transfer.
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公开(公告)号:USD891830S1
公开(公告)日:2020-08-04
申请号:US29709614
申请日:2019-10-16
Applicant: Beckman Coulter, Inc.
Designer: Matthew S. Davis , Jared L. West
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公开(公告)号:US08962308B2
公开(公告)日:2015-02-24
申请号:US13747722
申请日:2013-01-23
Applicant: Beckman Coulter, Inc.
Inventor: Brian D. Wilson , Sami D. Alaruri , Matthew S. Davis , Matthew D. Erickson , Alan N. Johnson , Garrick A. Maurer , Mark F. Sauerburger , Daniel R. Schmidt , Joshua D. Wiltsie , Thomas M. Stachelek , David L. Yang
IPC: C12M1/00 , G01N1/31 , B01L3/00 , B01L7/00 , G01N35/00 , G01N35/04 , C12Q3/00 , G05B13/02 , G01F23/24 , G01F23/26 , G06F19/10 , B01L3/02 , C12M1/34 , C12Q1/68 , G01N1/38 , G01N35/10
CPC classification number: G01N35/04 , B01L3/021 , B01L3/0275 , B01L3/50825 , B01L3/5085 , B01L3/50851 , B01L3/52 , B01L3/545 , B01L7/52 , B01L2200/025 , B01L2200/0642 , B01L2200/0668 , B01L2200/12 , B01L2200/147 , B01L2300/021 , B01L2300/022 , B01L2300/024 , B01L2300/042 , B01L2300/044 , B01L2300/045 , B01L2300/046 , B01L2300/0654 , B01L2300/0851 , B01L2300/123 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B01L2400/043 , C12M41/12 , C12P19/34 , C12Q1/68 , C12Q1/686 , C12Q3/00 , G01F23/24 , G01F23/26 , G01N1/31 , G01N1/38 , G01N35/00732 , G01N35/0092 , G01N35/0098 , G01N35/1002 , G01N35/1011 , G01N35/1016 , G01N35/1081 , G01N2035/00435 , G01N2035/00752 , G01N2035/00851 , G01N2035/0413 , G01N2035/0415 , G01N2035/0436 , G01N2035/0465 , G01N2035/0475 , G01N2035/1013 , G01N2035/1025 , G01N2035/1048 , G01N2035/1051 , G01N2035/1076 , G05B13/02 , G05B13/0205 , G06F19/10 , Y10T436/113332
Abstract: Systems and methods for processing and analyzing samples are disclosed. The system may process samples, such as biological fluids, using assay cartridges which can be processed at different processing locations. In some cases, the system can be used for PCR processing. The different processing locations may include a preparation location where samples can be prepared and an analysis location where samples can be analyzed. To assist with the preparation of samples, the system may also include a number of processing stations which may include processing lanes. During the analysis of samples, in some cases, thermal cycler modules and an appropriate optical detection system can be used to detect the presence or absence of certain nucleic acid sequences in the samples. The system can be used to accurately and rapidly process samples.
Abstract translation: 公开了用于处理和分析样品的系统和方法。 该系统可以使用可在不同处理位置处理的测定盒来处理样品,例如生物流体。 在某些情况下,该系统可用于PCR处理。 不同的处理位置可以包括可以准备样品的准备位置和可以分析样品的分析位置。 为了帮助准备样品,系统还可以包括可以包括加工车道的多个处理站。 在样品分析期间,在某些情况下,可以使用热循环仪模块和适当的光学检测系统来检测样品中某些核酸序列的存在或不存在。 该系统可用于准确快速地处理样品。
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