公开(公告)号：US20080002041A1

公开(公告)日：2008-01-03

申请号：US11734276

申请日：2007-04-12

申请人： Charles Chuang ,  Qing Guo ,  John Gilbert

发明人： Charles Chuang ,  Qing Guo ,  John Gilbert

IPC分类号： H04N5/217

CPC分类号： H04N9/3194 ,  H04N9/3185

摘要： A system and method for correcting optical distortions on an image acquisition system by scanning and mapping the image acquisition system and adjusting the content of output pixels. The optical distortion correction can be performed either at the camera end or at the display receiving end.

摘要翻译： 一种用于通过扫描和映射图像采集系统并调整输出像素的内容来校正图像采集系统上的光学失真的系统和方法。 可以在相机端或显示器接收端执行光学失真校正。

公开(公告)号：US09864243B2

公开(公告)日：2018-01-09

申请号：US12780749

申请日：2010-05-14

申请人： Gopal Erinjippurath ,  John Gilbert

发明人： Gopal Erinjippurath ,  John Gilbert

IPC分类号： G02F1/1347 ,  G09G3/34 ,  H04N13/04 ,  G02F1/1335

CPC分类号： G02F1/13471 ,  G02F1/133606 ,  G02F2001/133601 ,  G09G3/3426 ,  G09G2300/023 ,  G09G2320/0646 ,  G09G2360/16 ,  H04N13/324 ,  H04N13/337 ,  H04N13/351

摘要： A display provides increased contrast and resolution via first LCD panel energized to generate an image and a second LCD panel configured to increase contrast of the image. The second panel is an LCD panel without color filters and is configured to increase contrast by decreasing black levels of dark portions of images (making them blacker or darker) using polarization rotation and filtration. Preferably, the second LCD panel is of higher resolution than the first LCD panel. The panels may be directly illuminated or edge lit, and may be globally or locally dimmed monochrome or multi primary lights that may also include individual control of color intensities for each image or frame displayed. The panels may be placed in any order, but preferably are arranged such that active layers in each panel are as close together as possible. Brightness is maintained by the combination of reusing polarization between the panels and by not going through more than one set of color filters. Improved contrast is a result of using multiple light modulators in series.

公开(公告)号：US09772530B2

公开(公告)日：2017-09-26

申请号：US13472076

申请日：2012-05-15

申请人： John Gilbert

发明人： John Gilbert

IPC分类号： G02F1/1347 ,  G09G3/34 ,  H04N13/04 ,  G02F1/1335

CPC分类号： G02F1/13471 ,  G02F1/133606 ,  G02F2001/133601 ,  G09G3/3426 ,  G09G2300/023 ,  G09G2320/0646 ,  G09G2360/16 ,  H04N13/324 ,  H04N13/337 ,  H04N13/351

摘要： A display provides increased contrast and resolution via first LCD panel energized to generate an image and a second LCD panel configured to increase contrast of the image. The second panel is an LCD panel without color filters and is configured to increase contrast by decreasing black levels of dark portions of images using polarization rotation and filtration. The second LCD panel may have higher resolution than the first LCD panel. A half wave plate and/or film is placed in between the first and the second panel. The panels may be directly illuminated or edge lit, and may be globally or locally dimmed lights that may also include individual control of color intensities for each image or frame displayed.

公开(公告)号：US08567608B2

公开(公告)日：2013-10-29

申请号：US12499254

申请日：2009-07-08

申请人： Manish Deshpande ,  John Gilbert

发明人： Manish Deshpande ,  John Gilbert

IPC分类号： B07C5/00

CPC分类号： B07C5/36 ,  B01L3/5027 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502761 ,  B01L2200/0652 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2400/0487 ,  B07C5/02 ,  B07C5/34 ,  F15C5/00 ,  F16K99/0001 ,  F16K99/0019 ,  F16K99/0028 ,  F16K99/0046 ,  F16K99/0048 ,  G01N15/10 ,  G01N15/14 ,  G01N2015/1075 ,  G01N2015/1081 ,  G01N2015/1477 ,  G01N2015/149 ,  G01N2015/1497 ,  Y10S209/906 ,  Y10S209/932

摘要： A method and apparatus for sorting particles moving through a closed channel system of capillary size comprises a bubble valve for selectively generating a pressure pulse to separate a particle having a predetermined characteristic from a stream of particles. The particle sorting system may further include a buffer for absorbing the pressure pulse. The particle sorting system may include a plurality of closely coupled sorting modules which are combined to further increase the sorting rate. The particle sorting system may comprise a multi-stage sorting device for serially sorting streams of particles, in order to decrease the error rate.

公开(公告)号：US20080030865A1

公开(公告)日：2008-02-07

申请号：US11906621

申请日：2007-10-03

申请人： John Gilbert ,  Edward Sinofsky ,  Manish Deshpande

发明人： John Gilbert ,  Edward Sinofsky ,  Manish Deshpande

IPC分类号： G02B27/14

CPC分类号： G01N15/1434 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/6452 ,  G01N2015/1081

摘要： An optical system for acquiring fast spectra from spatially channel arrays includes a light source for producing a light beam that passes through the microfluidic chip or the channel to be monitored, one or more lenses or optical fibers for capturing the light from the light source after interaction with the particles or chemicals in the microfluidic channels, and one or more detectors. The detectors, which may include light amplifying elements, detect each light signal and transducer the light signal into an electronic signal. The electronic signals, each representing the intensity of an optical signal, pass from each detector to an electronic data acquisition system for analysis. The light amplifying element or elements may comprise an array of phototubes, a multianode phototube, or a multichannel plate based image intensifier coupled to an array of photodiode detectors.

摘要翻译： 用于从空间通道阵列获取快速光谱的光学系统包括用于产生穿过微流体芯片或待监测通道的光束的光源，用于在相互作用之后捕获来自光源的光的一个或多个透镜或光纤 微流体通道中的颗粒或化学物质，以及一个或多个检测器。 可以包括光放大元件的检测器检测每个光信号并将光信号转换成电子信号。 每个表示光信号强度的电子信号从每个检测器传递到电子数据采集系统进行分析。 光放大元件可以包括耦合到光电二极管检测器阵列的光管阵列，多子光电管或基于多通道板的图像增强器。

公开(公告)号：US20070298171A1

公开(公告)日：2007-12-27

申请号：US11811021

申请日：2007-06-08

申请人： John Gilbert ,  Sebastian Bohm

发明人： John Gilbert ,  Sebastian Bohm

IPC分类号： B05D3/10 ,  B23P17/04

CPC分类号： B01L3/0248 ,  B01L3/0244 ,  B01L3/5088 ,  B01L9/543 ,  B01L2200/12 ,  B01L2200/142 ,  B01L2200/143 ,  B01L2200/147 ,  B01L2300/161 ,  B01L2300/1822 ,  B01L2400/0439 ,  G01N2035/1037 ,  Y10S977/888 ,  Y10T29/49 ,  Y10T436/2575

摘要： A cooled liquid sample dispensing system comprises a pair of pins for holding a droplet of liquid therebetween and a cooling element. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The pins acquire and hold a droplet of the liquid sample in the sample acquisition region formed in the space between the tips and apply the droplet to a selected sample handing system. The cooling element, when activated, cools the droplet of liquid to reduce evaporation.

摘要翻译： 冷却的液体样品分配系统包括用于在其间保持液滴的一对销和冷却元件。 每个引脚包括与另一个引脚间隔预定距离的尖端以限定采样区域。 这些销钉在液体样品的液滴中形成在尖端之间的空间中形成的样品采集区域，并将液滴施加到选定的样品处理系统上。 冷却元件在启动时会冷却液滴以减少蒸发。

公开(公告)号：US07258839B2

公开(公告)日：2007-08-21

申请号：US10328973

申请日：2002-12-23

申请人： John Gilbert ,  Sebastian Böhm

发明人： John Gilbert ,  Sebastian Böhm

IPC分类号： B01L3/02 ,  G01N1/10

CPC分类号： B01L3/0248 ,  B01L3/0244 ,  B01L3/5088 ,  B01L9/543 ,  B01L2200/12 ,  B01L2200/142 ,  B01L2200/143 ,  B01L2200/147 ,  B01L2300/161 ,  B01L2300/1822 ,  B01L2400/0439 ,  G01N2035/1037 ,  Y10S977/888 ,  Y10T29/49 ,  Y10T436/2575

摘要： A cooled liquid sample dispensing system comprises a pair of pins for holding a droplet of liquid therebetween and a cooling element. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The pins acquire and hold a droplet of the liquid sample in the sample acquisition region formed in the space between the tips and apply the droplet to a selected sample handing system. The cooling element, when activated, cools the droplet of liquid to reduce evaporation.

公开(公告)号：US20070148777A1

公开(公告)日：2007-06-28

申请号：US11702792

申请日：2007-02-06

申请人： John Gilbert ,  Nghia Chiem

发明人： John Gilbert ,  Nghia Chiem

IPC分类号： G01N37/00

CPC分类号： G01N27/44791 ,  B01D57/02 ,  B01F13/0059 ,  B01F13/0071 ,  B01J19/0093 ,  B01J2219/00371 ,  B01J2219/00378 ,  B01J2219/00783 ,  B01J2219/00831 ,  B01J2219/00837 ,  B01J2219/00869 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00905 ,  B01L3/0244 ,  B01L3/0268 ,  B01L3/502715 ,  B01L3/502792 ,  B01L2200/027 ,  B01L2200/143 ,  B01L2200/147 ,  B01L2300/087 ,  B01L2300/089 ,  B01L2400/0406 ,  B01L2400/0415 ,  B01L2400/0421 ,  B01L2400/0439 ,  B01L2400/0487 ,  C12Q1/00 ,  G01N27/447 ,  G01N27/44743 ,  G01N27/44782 ,  G01N2035/1037 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/118339 ,  Y10T436/13 ,  Y10T436/25 ,  Y10T436/25375 ,  Y10T436/2575

摘要： A fluid interface port in a microfluidic system and a method of forming the fluid interface port is provided. The fluid interface port comprises an opening formed in the side wall of a microchannel sized and dimensioned to form a virtual wall when the microchannel is filled with a first liquid. The fluid interface port is utilized to perform a labeling operation on a sample.

摘要翻译： 提供微流体系统中的流体接口端口和形成流体接口端口的方法。 流体接口端口包括形成在微通道的侧壁中的开口，其尺寸和尺寸被设计成当微通道充满第一液体时形成虚拟壁。 流体接口端口用于对样品执行标签操作。

公开(公告)号：US07179423B2

公开(公告)日：2007-02-20

申请号：US10028852

申请日：2001-12-21

申请人： Sebastian Böhm ,  John Gilbert

发明人： Sebastian Böhm ,  John Gilbert

IPC分类号： B01L3/02 ,  B01L11/00 ,  B32B5/02 ,  B32B27/04 ,  B32B27/12

CPC分类号： B01F13/0059 ,  B01D57/02 ,  B01J19/0093 ,  B01J2219/00371 ,  B01J2219/00378 ,  B01J2219/00783 ,  B01J2219/00831 ,  B01J2219/00837 ,  B01J2219/00869 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/00905 ,  B01L3/0244 ,  B01L3/0268 ,  B01L3/502715 ,  B01L3/502792 ,  B01L2200/027 ,  B01L2200/143 ,  B01L2200/147 ,  B01L2300/089 ,  B01L2400/0421 ,  B01L2400/0439 ,  C12Q1/00 ,  G01N27/447 ,  G01N27/44743 ,  G01N27/44782 ,  G01N27/44791 ,  G01N2035/1037 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/118339 ,  Y10T436/2575

摘要： A fluid interface port in a microfluidic system and a method of forming the fluid interface port is provided. The fluid interface port comprises an opening formed in the side wall of a microchannel sized and dimensioned to form a virtual wall when the microchannel is filled with a first liquid. The fluid interface port is utilized to fill the microchannel with a first liquid, to introduce a second liquid into the first liquid and to eject fluid from the microchannel.

摘要翻译： 提供微流体系统中的流体接口端口和形成流体接口端口的方法。 流体接口端口包括形成在微通道的侧壁中的开口，其尺寸和尺寸被设计成当微通道充满第一液体时形成虚拟壁。 流体接口端口用于用第一液体填充微通道，以将第二液体引入第一液体并从微通道喷射流体。

公开(公告)号：US20060285983A1

公开(公告)日：2006-12-21

申请号：US11362411

申请日：2006-02-23

申请人： Bernard Bunner ,  Manish Deshpande ,  Sebastian Bohm ,  Richard Day ,  John Gilbert

发明人： Bernard Bunner ,  Manish Deshpande ,  Sebastian Bohm ,  Richard Day ,  John Gilbert

IPC分类号： F04B17/00

CPC分类号： F04B43/025 ,  F04B43/04 ,  F04B43/043 ,  Y10S977/963

摘要： An electromagnetic micropump for pumping small volumes of liquids and gases comprises a magnetic actuator assembly, a flexible membrane and a housing defining a chamber and a plurality of valves. The magnetic actuator assembly comprises a coil and a permanent magnet for deflecting the membrane to effect pumping of the fluid. A plurality of micropumps may be stacked together to increase pumping capacity.