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公开(公告)号：US20090294655A1
公开(公告)日：2009-12-03
申请号：US12298968
申请日：2007-04-13
Applicant: Chuanfan Ding , Li Ding
Inventor： Chuanfan Ding , Li Ding
CPC classification number: H01J49/4225 , H01J49/004 , H01J49/065 , H01J49/4235
Abstract: The invention “Ion Trap Array (ITA)” pertains generally to the field of ion storage and analysis technologies, and particularly to the ion storing apparatus and mass spectrometry instruments which separate ions by its character such as mass-to-charge ratio. The aim of this invention is providing an apparatus for ion storage and analysis comprising at least two or more rows of parallel placed electrode array wherein each electrode array includes at least two or more parallel bar-shaped electrodes, by applying different phase of alternating current voltages on different bar electrodes to create alternating electric fields inside the space between two parallel electrodes of different rows of electrode arrays, multiple linear ion trapping fields paralleled constructed in the space between the different rows of electrode arrays which are open to adjacent each other without a real barrier. This invention also provides a method for ion storage and analysis involving with the trapping, cooling and mass-selected analyzing of ions by this apparatus mentioned which constructs multiple conjoint linear ion trapping fields in the space between the different rows of electrode arrays
Abstract translation: 本发明“离子阱阵列（ITA）”一般涉及离子存储和分析技术领域，特别涉及离子存储装置和质谱仪器，它们通过诸如质荷比的特性分离离子。 本发明的目的是提供一种用于离子存储和分析的装置，其包括至少两行或多行平行放置的电极阵列，其中每个电极阵列包括至少两个或更多个平行的棒状电极，通过施加不同相位的交流电压 在不同的棒电极上在不同行电极阵列的两个平行电极之间的空间内部产生交替电场，多个线性离子俘获场平行地构造在电极阵列的不同行之间的空间中，这些空间彼此相邻而没有实际 屏障。 本发明还提供一种离子存储和分析的方法，其涉及通过所述装置进行的捕获，冷却和质量选择的离子分析，其构造了在不同行电极阵列之间的空间中的多个联合线性离子捕获场
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公开(公告)号：US09111741B2
公开(公告)日：2015-08-18
申请号：US12298968
申请日：2007-04-13
Applicant: Chuanfan Ding , Li Ding
Inventor： Chuanfan Ding , Li Ding
CPC classification number: H01J49/4225 , H01J49/004 , H01J49/065 , H01J49/4235
Abstract: The invention “Ion Trap Array (ITA)” pertains generally to the field of ion storage and analysis technologies, and particularly to the ion storing apparatus and mass spectrometry instruments which separate ions by its character such as mass-to-charge ratio. The aim of this invention is providing an apparatus for ion storage and analysis comprising at least two or more rows of parallel placed electrode array wherein each electrode array includes at least two or more parallel bar-shaped electrodes, by applying different phase of alternating current voltages on different bar electrodes to create alternating electric fields inside the space between two parallel electrodes of different rows of electrode arrays, multiple linear ion trapping fields paralleled constructed in the space between the different rows of electrode arrays which are open to adjacent each other without a real barrier. This invention also provides a method for ion storage and analysis involving with the trapping, cooling and mass-selected analyzing of ions by this apparatus mentioned which constructs multiple conjoint linear ion trapping fields in the space between the different rows of electrode arrays.
Abstract translation: 本发明“离子阱阵列（ITA）”一般涉及离子存储和分析技术领域，特别涉及离子存储装置和质谱仪器，它们通过诸如质荷比的特性分离离子。 本发明的目的是提供一种用于离子存储和分析的装置，其包括至少两行或多行平行放置的电极阵列，其中每个电极阵列包括至少两个或更多个平行的棒状电极，通过施加不同相位的交流电压 在不同的棒电极上在不同行电极阵列的两个平行电极之间的空间内部产生交替电场，多个线性离子俘获场平行地构造在电极阵列的不同行之间的空间中，这些空间彼此相邻而没有实际 屏障。 本发明还提供了一种离子存储和分析的方法，其涉及通过所述装置进行捕集，冷却和质量选择的离子分析，其在不同行电极阵列之间的空间中构成多个联合线性离子捕获场。
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公开(公告)号：US20240341483A1
公开(公告)日：2024-10-17
申请号：US18300768
申请日：2023-04-14
Applicant: Li Ding
Inventor： Li Ding
IPC: A47C7/46
CPC classification number: A47C7/462
Abstract: A lumbar pillow that can move with the load bearing of the waist in 3D, comprising the lumbar pillow body, the middle part of the rear end of the lumbar pillow body is provided with a spring central axis mechanism; the spring central axis mechanism comprises the upper bottom plate, the spring and the lower bottom plate, the upper bottom plate is arranged in the middle of the rear end of the lumbar pillow body, the upper bottom plate is provided with a spring, and the other end of the spring is provided with a lower bottom plate; the middle part of the rear end of the lumbar pillow body is provided with a spring central axis mechanism, so that the upper bottom plate will be supported on the backrest of the seat, when the waist leans on the lumbar pillow, the spring will support the lumbar pillow.
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公开(公告)号：US09633143B2
公开(公告)日：2017-04-25
申请号：US14110703
申请日：2012-04-05
Applicant: Milton Santano Elias Carrasco , Daniel Akwera Shihundu , Billy Siu Fai Chan , Steven Kin-Shing Cheng , Christian Grant Milne , Guanggui Pei , Darren Earl Brown , Li Ding
Inventor： Milton Santano Elias Carrasco , Daniel Akwera Shihundu , Billy Siu Fai Chan , Steven Kin-Shing Cheng , Christian Grant Milne , Guanggui Pei , Darren Earl Brown , Li Ding
CPC classification number: G06F17/5009 , G06F17/5095
Abstract: A method, apparatus, media and signals for generating a computer representation of a three-dimensional swept envelope of a vehicle having a wheeled chassis operable to support a vehicle body for movement along a terrain is disclosed. The method involves receiving terrain data representing a 3D terrain, receiving data defining parameters of the vehicle, and receiving data defining a path for movement of the vehicle from an initial position on the terrain to a displaced position on the terrain. The method also involves disposing a computer representation of the vehicle on the 3D representation of the terrain at successive locations along the path using the parameters. Disposing involves determining points of engagement between wheels of the wheeled chassis and the 3D representation of the terrain to dispose the chassis with respect to the terrain, and determining a corresponding 3D location of the vehicle body with respect to the terrain. The method further involves generating a plurality of spatial extents of the vehicle at the successive locations, the spatial extents defining the 3D swept envelope of the vehicle when moving between the initial position and the displaced position. In another aspect a method for generating a computer representation of a three-dimensional swept envelope of an object moving along a guideway disposed with respect to a 3D representation of a terrain is disclosed.
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公开(公告)号：US20130138093A1
公开(公告)日：2013-05-30
申请号：US13686952
申请日：2012-11-28
Applicant: Wayne H. Knox , Li Ding , Jay F. Kunzler , Dharmendra Jani , Candido D. Pinto
Inventor： Wayne H. Knox , Li Ding , Jay F. Kunzler , Dharmendra Jani , Candido D. Pinto
CPC classification number: A61F2/14 , A61B18/20 , A61F2/142 , A61F2/1451 , A61F2/147 , A61F2/16 , A61F9/008 , A61L27/16 , A61L27/18 , A61L27/52 , B29D11/00355 , B29D11/00461 , B29D11/023 , B29K2083/00 , B29K2105/0061 , C08J7/12 , C08J7/123 , C08J2333/14 , C08J2339/06 , C08J2383/04 , G02B1/041 , G02C7/022 , G02C2202/12 , G02C2202/14
Abstract: An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer.
Abstract translation: 一种光学装置，包括具有已经用激光照射的选择区域的光学水凝胶，所述激光具有0.01nJ至50nJ的脉冲能量和600nm至900nm的波长。 照射区域的特征在于折射率的正变化为0.01至0.06，并且表现出很小的或没有散射损失。 用亲水性单体制备光学水凝胶。
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Patent Agency Ranking
公开(公告)号：US20130026359A1
公开(公告)日：2013-01-31
申请号：US13634190
申请日：2011-04-22
Applicant: Sumio Kumashiro , Wenjian Sun , Li Ding
Inventor： Sumio Kumashiro , Wenjian Sun , Li Ding
CPC classification number: H01J49/10 , G01N27/622 , H01J49/066 , H01J49/161 , H01J49/164 , H01J49/165 , H01J49/24
Abstract: The current invention involves a method and a device for generating and analyzing ions in order to analyze samples directly without sample preparation. The gaseous neutral molecules are desorbed under atmospheric pressure by a desorption method. The desorbed neutral molecules are then transferred into a low pressure region where they are post-ionized by a mist from an electrospray probe tip or by photons from a vacuum UV source. The generated ions are then focused in a time varying electric field in the low pressure chamber before they are transferred into a mass spectrometer or ion mobility spectrometer for further analysis.
Abstract translation: 本发明涉及用于生成和分析离子的方法和装置，以便在不进行样品制备的情况下直接分析样品。 气态中性分子通过解吸法在大气压下解吸。 然后将解吸的中性分子转移到低压区域，在那里它们被来自电喷雾探针尖端的雾或者来自真空UV源的光子后离子化。 然后将所产生的离子聚焦在低压室中的时变电场中，然后将其转移到用于进一步分析的质谱仪或离子迁移谱仪中。
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7.发明授权公开(公告)号：US08025892B2
公开(公告)日：2011-09-27
申请号：US10017259
申请日：2001-11-12
Applicant: Pascal E. Delrieu , Li Ding
Inventor： Pascal E. Delrieu , Li Ding
CPC classification number: A61K8/042 , A61K8/025 , A61K8/11 , A61K8/365 , A61K8/645 , A61K8/676 , A61K8/73 , A61K8/731 , A61K8/735 , A61K2800/56 , A61Q19/00 , Y10S514/937 , Y10S514/944
Abstract: Gel particles or beads can be prepared by forming a hot aqueous solution of a gelling agent, and discharging the hot gelling agent solution through a discharge orifice into a cold moving stream of hydrophobic liquid so that the gelling agent solution cools rapidly and good quality gel particles coalesce in the cold hydrophobic liquid stream. The cold hydrophobic liquid stream can be contained in a conduit so that the cold hydrophobic liquid stream moves past the discharge orifice and exerts a force on hot solution in the discharge orifice, the force acting to withdraw the hot solution from the discharge orifice. Optionally, the gel particles can be crushable gel beads 10 formed of an agar complex providing cosmetic, pharmaceutical, etc. delivery vehicles for topical delivery of biologically or cosmetically active agents. Preferred agar beads 10 are complexes of a continuous phase of agar gel 12 in a self-supporting solid or semi-solid form with a restraining polymer 14. Various active agents 16 may be bound to restraining polymer 14, for, example ascorbic acid, lactic acid or papain.
Abstract translation: 可以通过形成热胶凝剂的水溶液，并将热胶凝剂溶液通过排出孔排出到冷流动的疏水液体中，使得胶凝剂溶液快速冷却，并且优质的凝胶颗粒 在冷疏水性液体流中聚结。 冷疏水性液体流可以包含在导管中，使得冷的疏水性液体流移动通过排出孔，并且在排出孔中的热溶液上施加力，该力用于从排出孔抽出热溶液。 任选地，凝胶颗粒可以是由琼脂复合物形成的可压碎凝胶珠10，其提供用于局部递送生物或化妆活性剂的化妆品，药物等递送载体。 优选的琼脂珠10是具有抑制聚合物14的自支撑固体或半固体形式的琼脂凝胶12的连续相的复合物。各种活性剂16可以与约束聚合物14结合，例如抗坏血酸，乳酸 酸或木瓜蛋白酶。
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公开(公告)号：US20110049352A1
公开(公告)日：2011-03-03
申请号：US12552476
申请日：2009-09-02
Applicant: Li Ding , Wenjian Sun
Inventor： Li Ding , Wenjian Sun
CPC classification number: H01J49/162 , H01J49/0463 , H01J49/165
Abstract: This invention relates to a desorpton/ionization source operated under ambient conditions for direct analysis of solid or liquid samples on a surface. The source comprises of a laser desorption system and a UV/electrospray combined ionization system. The source is suitable for simultaneously ionizing samples with different polarity in a complex mixture. At the same time, the compact design of the source with multiple channels can maintain the level of local concentration of the analyte ions inside the source for higher efficiency of sample ionization and introduction.
Abstract translation: 本发明涉及在环境条件下操作的用于在表面上直接分析固体或液体样品的解吸/离子源。 该源包括激光解吸系统和UV /电喷雾组合电离系统。 该源适用于在复杂混合物中同时电离不同极性的样品。 同时，具有多个通道的源的紧凑设计可以保持源内的分析物离子的局部浓度水平，以提高样品电离和引入的效率。
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公开(公告)号：US07897916B2
公开(公告)日：2011-03-01
申请号：US10598194
申请日：2005-02-23
Applicant: Michael Sudakov , Li Ding
Inventor： Michael Sudakov , Li Ding
IPC: H01J49/42
CPC classification number: H01J49/40 , H01J49/004 , H01J49/423
Abstract: A tandem linear ion trap and time-of-flight mass spectrometer, where the ion trap has a straight central axis orthogonal to the flight path of the mass spectrometer. The ion trap comprises a set of electrodes, (401, 403, 402, 404) at least one of the electrodes has a slit for ejecting ions towards the mass spectrometer; a set of DC voltage supplies (+V, −V, V1, V2) to provide discrete DC levels and a number of fast electronic switches (409) for connecting/disconnecting the DC supplies to at least two of the electrodes; a neutral gas filling the ion trap and a digital controller to provide a switching procedure of ion trapping, manipulation with ions, cooling and including a state at which all ions are ejected from the ion trap towards the mass spectrometer.
Abstract translation: 串联线性离子阱和飞行时间质谱仪，其中离子阱具有与质谱仪的飞行路径正交的直的中心轴。 离子阱包括一组电极（401,403,402,404），至少一个电极具有用于向质谱仪喷射离子的狭缝; 一组直流电压源（+ V，-V，V1，V2）以提供离散DC电平以及用于将DC电源连接/断开至少两个电极的多个快速电子开关（409） 填充离子阱的中性气体和数字控制器，以提供离子捕获，用离子的操作，冷却和包括从离子阱向质谱仪喷射所有离子的状态的切换过程。
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公开(公告)号：US07893401B2
公开(公告)日：2011-02-22
申请号：US12158458
申请日：2006-12-20
Applicant: Li Ding
Inventor： Li Ding
IPC: H01J49/04
CPC classification number: H01J49/062 , H01J49/0481 , H01J49/164
Abstract: A mass spectrometer has a pulsed ion source, a first ion trap (10) for trapping ions generated by the pulsed ion source and for locating trapped ions for subsequent ejection from the first ion trap. A pulse of cooling gas is introduced into the first ion trap (10) at a peak pressure suitable for enabling the first ion trap (10) to trap ions. A turbomolecular pump (17) reduces the pressure of cooling gas before the trapped ions are ejected from the first ion trap (1) towards a second ion trap (20) for analysis. The pulsed ion source has a sample plate (14) which forms an end wall of the first ion trap (10).
Abstract translation: 质谱仪具有脉冲离子源，第一离子阱（10），用于捕获由脉冲离子源产生的离子，并用于定位捕获的离子用于随后从第一离子阱排出。 将冷却气体的脉冲以适于使第一离子阱（10）捕获离子的峰值压力引入到第一离子阱（10）中。 涡轮分子泵（17）在被捕获的离子从第一离子阱（1）向第二离子阱（20）排出之前降低冷却气体的压力，用于分析。 脉冲离子源具有形成第一离子阱（10）的端壁的样品板（14）。
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