Solar power bank
    3.
    外观设计

    公开(公告)号:USD971821S1

    公开(公告)日:2022-12-06

    申请号:US29805523

    申请日:2021-08-27

    申请人: Jing Wei

    设计人: Jing Wei

    Methods and compositions for the treatment of metabolic syndrome
    7.
    发明申请
    Methods and compositions for the treatment of metabolic syndrome 审中-公开
    用于治疗代谢综合征的方法和组合物

    公开(公告)号:US20080081781A1

    公开(公告)日:2008-04-03

    申请号:US11784294

    申请日:2007-04-06

    CPC分类号: A61K31/4375

    摘要: Methods and compositions containing a berberine compound or berberine related or proto-berberine or derivative compound are provided for the prevention and treatment of metabolic and cardiovascular disorders including metabolic syndrome, hyperlipidemia, obesity, diabetes, insulin resistance, hyperglycemia, hypertension and elevated cholesterol in mammalian subjects. The methods and compositions of the invention are effective for prevention and treatment of metabolic syndrome, hyperlipidemia, obesity, diabetes, insulin resistance, hyperglycemia, hypertension and elevated cholesterol. Additional compositions and methods are provided which employ a berberine compound or berberine related or derivative compound in combination with a second anti-therapeutic agent to yield more effective treatment tools against metabolic disorders, and/or dual activity therapeutic methods and formulations useful to prevent or reduce hyperlipidemia and/or hyperglycemia and one or more causal or related symptoms or conditions associated with hyperlipidemia and/or hyperglycemia in mammalian subjects.

    摘要翻译: 提供含有小檗碱化合物或小檗碱相关或原小​​檗碱或衍生化合物的方法和组合物用于预防和治疗哺乳动物代谢和心血管疾病,包括代谢综合征,高脂血症,肥胖,糖尿病,胰岛素抵抗,高血糖,高血压和升高的胆固醇 科目。 本发明的方法和组合物可有效预防和治疗代谢综合征,高脂血症,肥胖症,糖尿病,胰岛素抵抗,高血糖症,高血压和升高的胆固醇。 提供了额外的组合物和方法,其使用小檗碱化合物或小檗碱相关或衍生化合物与第二抗治疗剂组合以产生针对代谢紊乱的更有效的治疗工具,和/或可用于预防或减少的双重活性治疗方法和制剂 高脂血症和/或高血糖症和哺乳动物受试者中与高脂血症和/或高血糖相关的一个或多个因果或相关症状或病症。

    Precipitating Substrate for Bio-Layer Interferometry
    9.
    发明申请
    Precipitating Substrate for Bio-Layer Interferometry 审中-公开
    用于生物层干涉测量的沉淀底物

    公开(公告)号:US20110236911A1

    公开(公告)日:2011-09-29

    申请号:US13052001

    申请日:2011-03-18

    IPC分类号: G01N33/53 C12M1/34

    摘要: Improved apparatus, compositions, and methods for carrying out interferometry-based assays for detecting analytes in a sample through the use of a precipitating substrate to enhance an interferometry binding signal, and kits useful for carrying out these assays. Methods comprise providing an optical assembly comprising an optical element with a transparent material and adapted for coupling to a light source via a fiber, a first reflective surface and a second reflecting surface having a first analyte-binding molecule and separated from said first surface by a distance, d, exposing said optical element to a sample comprising said analyte, a second analyte binding molecule, and a precipitating substrate; and detecting a change in thickness at said first reflective surface thereby detecting said analyte in said sample. Kits include reagents for derivatizing assay components along with packaging and instructions for use.

    摘要翻译: 改进的用于进行基于干涉测定的测定法的装置,组合物和方法,用于通过使用沉淀底物来增强干涉测量结合信号来检测样品中的分析物,以及可用于进行这些测定的试剂盒。 方法包括提供光学组件,其包括具有透明材料的光学元件,并且适于经由光纤耦合到光源,第一反射表面和具有第一分析物结合分子的第二反射表面,并且从所述第一表面与所述第一表面分离 距离d,将所述光学元件暴露于包含所述分析物的样品,第二分析物结合分子和沉淀基底; 并检测所述第一反射表面的厚度变化,从而检测所述样品中的所述分析物。 试剂盒包括用于衍生测定组分的试剂以及包装和使用说明书。

    Methods And Compositions For The Treatment of Hyperlipidemia
    10.
    发明申请
    Methods And Compositions For The Treatment of Hyperlipidemia 审中-公开
    用于治疗高脂血症的方法和组合

    公开(公告)号:US20110158932A1

    公开(公告)日:2011-06-30

    申请号:US12330447

    申请日:2008-12-08

    CPC分类号: A61K31/4375

    摘要: Methods and compositions containing a berberine compound or berberine related or derivative compound are provided for the prevention and treatment of hyperlipidemia, elevated cholesterol, and/or cardiovascular disease in mammalian subjects. The methods and compositions of the invention are effective for prevention and treatment of atherosclerosis, coronary artery disease, angina pectoris, carotid artery disease, stroke, cerebral arteriosclerosis, high blood pressure, myocardial infarction, cerebral infarction, restenosis following balloon angioplasty, intermittent claudication, dyslipidemia post-prandial lipidemia or xanthoma. Additional compositions and methods are provided which employ a berberine compound or berberine related or derivative compound in combination with a second anti-hyperlipidemia agent, or a different therapeutic agent to yield more effective treatment tools against hyperlipidemia and/or cardiovascular disease, and/or dual activity therapeutic methods and formulations useful to prevent or reduce hyperlipidemia and one or more causal or related symptoms or conditions associated with hyperlipidemia in mammalian subjects.

    摘要翻译: 提供含有小檗碱化合物或小檗碱相关或衍生化合物的方法和组合物用于预防和治疗哺乳动物受试者中的高脂血症,升高的胆固醇和/或心血管疾病。 本发明的方法和组合物可有效预防和治疗动脉粥样硬化,冠状动脉疾病,心绞痛,颈动脉疾病,中风,脑动脉硬化,高血压,心肌梗塞,脑梗塞,球囊血管成形术后的再狭窄,间歇性跛行, 餐后血脂异常或血清白血病。 提供了额外的组合物和方法,其使用小檗碱化合物或小檗碱相关或衍生化合物与第二抗高脂血症药物或不同治疗剂组合以产生更有效的治疗工具来抵抗高脂血症和/或心血管疾病和/或双重 用于预防或减少高脂血症的活性治疗方法和制剂以及与哺乳动物受试者中的高脂血症相关的一个或多个因果或相关症状或病症。