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34 条记录 (耗时 0.022 秒)

    Method and device for measuring, calibrating and using laser tweezers
    1.
    发明授权
    Method and device for measuring, calibrating and using laser tweezers 失效
    用于测量，校准和使用激光镊子的方法和装置

    公开(公告)号：US06991906B1

    公开(公告)日：2006-01-31

    申请号：US09582609

    申请日：1998-12-21

    申请人： Günter Fuhr ,  Thomas Schnelle ,  Torsten Müller ,  Hermine Hitzler ,  Karl-Otto Greulich ,  Shamoi Monajembashi

    发明人： Günter Fuhr ,  Thomas Schnelle ,  Torsten Müller ,  Hermine Hitzler ,  Karl-Otto Greulich ,  Shamoi Monajembashi

    IPC分类号： G01N33/53 ,  G01N33/543

    CPC分类号： H05H3/04 ,  G21K1/006

    摘要： To measure or exert optically-induced forces on at least one particle in the focus of an optical cage, the following steps are taken: a) the focus is positioned in a microelectrode arrangement with a three-dimensional electrical field that has a field gradient which forms an electrical capture area, and the focus is at a distance from the capture are and b) the amplitude of the electrical field, the light power of the light beam forming the optical cage, and/or the distance of the capture area from the focus are varied to detect which varied field property moves the particle from the focus to the capture area or vice versa, or at least to temporarily move the particle into the capture area.

    摘要翻译： 为了在光学保持架的焦点的至少一个颗粒上测量或施加光学诱导的力，采取以下步骤：a）焦点位于具有场梯度的三维电场的微电极布置中， 形成电捕获区域，并且聚焦距离捕获的距离为b）电场的幅度，形成光学笼的光束的光功率和/或捕获区域距离 改变焦点以检测哪个变化的场性质将粒子从焦点移动到捕获区域，反之亦然，或至少临时将颗粒移动到捕获区域中。

    Process and device for the detection of microscopically small objects
    3.
    发明授权
    Process and device for the detection of microscopically small objects 有权
    检测微小物体的过程和设备

    公开(公告)号：US06801311B1

    公开(公告)日：2004-10-05

    申请号：US09889908

    申请日：2001-12-12

    申请人： Günter Fuhr ,  Thomas Schnelle ,  Christoph Reichle ,  Henning Glasser ,  Torsten Müller

    发明人： Günter Fuhr ,  Thomas Schnelle ,  Christoph Reichle ,  Henning Glasser ,  Torsten Müller

    IPC分类号： G01N1502

    CPC分类号： B03C5/028 ,  B03C5/026 ,  G01N15/1031 ,  G01N15/1056 ,  G01N15/1484 ,  G01N2015/1006 ,  G01N2015/105 ,  G01N2015/1075 ,  G01N2015/1415 ,  G01N2015/1447 ,  G01N2015/1495

    摘要： For object detection, particularly in fluidic microsystems, optical imaging of at least one resting or moving object (10) on a structured mask (20) with at least one segment from a flat section (80), in which the object (10) is located at least partially or temporarily and which has a characteristic dimension smaller than the dimension of the object (10) or its movement path, to a detector unit, detection of the quantity of light transmitted by the structured mask (20), and generation of a detector signal which has a predetermined relationship with the quantity of light, and evaluation of the detector signal in regard to the presence of the object (10), its position, its shape and/or the temporal change of the position are performed.

    摘要翻译： 对于物体检测，特别是在流体微系统中，至少一个静止或移动的物体（10）在结构化掩模（20）上的光学成像，其具有来自平坦部分（80）的至少一个部分，其中物体（10） 至少部分地或临时地定位，并且具有比物体（10）或其移动路径的尺寸小的特征尺寸，到检测器单元，由结构化掩模（20）传输的光量的检测，以及 执行与光量具有预定关系的检测器信号，以及关于物体（10）的存在，其位置，形状和/或位置的时间变化的检测器信号的评估。

    Method and device for manipulating microparticles in fluid flows
    6.
    发明授权
    Method and device for manipulating microparticles in fluid flows 有权
    用于操纵流体流中微粒的方法和装置

    公开(公告)号：US06727451B1

    公开(公告)日：2004-04-27

    申请号：US09673034

    申请日：2000-11-30

    申请人： Günter Fuhr ,  Rolf Hagedorn ,  Torsten Müller ,  Thomas Schnelle ,  Gabriele Gradl

    发明人： Günter Fuhr ,  Rolf Hagedorn ,  Torsten Müller ,  Thomas Schnelle ,  Gabriele Gradl

    IPC分类号： B01D5702

    CPC分类号： B03C5/026 ,  C12M47/04

    摘要： To manipulate microparticles in a fluid that intersects a first channel or several first channels as a stream, one or more microparticles (14) are exposed to electrical field barriers that change their direction from the direction of flow toward the edge of the flow to a lateral hole (17) of the respective first channel. As a result, microparticles can be moved back and forth between streaming fluids. Preferred applications include treatment, separating, sorting or confinement procedures.

    摘要翻译： 为了操纵在与第一通道或多个第一通道相交的流体中的微粒作为流，一个或多个微粒暴露于电场屏障，其将其方向从流动方向朝向流动边缘改变为侧向 （17）。 结果，微粒可以在流动流体之间来回移动。 优选的应用包括处理，分离，分选或限制程序。

    METHODS AND DEVICES FOR SEPARATING PARTICLES IN A LIQUID FLOW
    8.
    发明申请
    METHODS AND DEVICES FOR SEPARATING PARTICLES IN A LIQUID FLOW 有权
    用于在液体流中分离颗粒的方法和装置

    公开(公告)号：US20120305398A1

    公开(公告)日：2012-12-06

    申请号：US13586988

    申请日：2012-08-16

    申请人： Torsten Müller ,  Thomas Schnelle ,  Rolf Hagedorn

    发明人： Torsten Müller ,  Thomas Schnelle ,  Rolf Hagedorn

    IPC分类号： B01D43/00

    CPC分类号： B03C5/005

    摘要： Methods and devices for the separation of particles (20, 21, 22) in a compartment (30) of a fluidic microsystem (100) are described, in which the movement of a liquid (10) in which particles (20, 21, 22) are suspended with a predetermined direction of flow through the compartment (30), and the generation of a deflecting potential in which at least a part of the particles (20, 21, 22) is moved relative to the liquid in a direction of deflection are envisaged, whereby further at least one focusing potential is generated, so that at least a part of the particles is moved opposite to the direction of deflection relative to the liquid by dielectrophoresis under the effect of high-frequency electrical fields, and guiding of particles with different electrical, magnetic or geometric properties into different flow areas (11, 12) in the liquid takes place.

    摘要翻译： 描述了用于在流体微系统（100）的隔室（30）中分离颗粒（20,21,22）的方法和装置，其中液体（10）的运动，其中颗粒（20,21,22 ）以预定的流动方向悬挂通过隔室（30），并产生偏转电位，其中至少一部分颗粒（20,21,22）相对于液体沿偏转方向移动 被设想为进一步产生至少一个聚焦电位，使得至少一部分颗粒在高频电场的作用下通过介电电泳相对于液体的偏转方向移动，并且引导颗粒 在不同的流动区域（11,12）中发生不同的电，磁或几何特性。

    MICROFLUIDIC SYSTEM AND CORRESPONDING OPERATING METHOD
    9.
    发明申请
    MICROFLUIDIC SYSTEM AND CORRESPONDING OPERATING METHOD 失效
    微流控系统及相应的操作方法

    公开(公告)号：US20110083961A1

    公开(公告)日：2011-04-14

    申请号：US12161267

    申请日：2007-01-17

    申请人： Torsten Müller ,  Thomas Schnelle

    发明人： Torsten Müller ,  Thomas Schnelle

    IPC分类号： G01N27/26 ,  B03C5/02

    CPC分类号： C12N13/00 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0645 ,  B01L2400/0421

    摘要： The invention relates to an operating method for a microfluidic system, including the following steps: feeding of a carrier flow with particles (5) of a first particle type suspended therein into the microfluidic system; charging of a plurality of electrical field cages (1′, 1″) in the microfluidic system with the supplied particles (5) of the first particle type; the supplying of a carrier flow with particles (6) of a second particle type suspended therein into the microfluidic system; and charging the field cages (1′, 1″) in the microfluidic system with the supplied particles (6) of the second particle type in such a manner that a particle (5) of the first particle type and a particle (6) of the second particle type is present in at least one of the field cages (1′, 1′). The invention also relates to a corresponding microfluidic system.

    摘要翻译： 本发明涉及一种用于微流体系统的操作方法，包括以下步骤：将载体流与悬浮于其中的第一颗粒类型的颗粒（5）进料到微流体系统中; 在微流体系统中与所提供的第一颗粒类型的颗粒（5）充电多个电场笼（1'，1“）; 将载体流与悬浮在其中的第二颗粒类型的颗粒（6）供应到微流体系统中; 以及将所述微流体系统中的所述场笼（1'，1“）与所提供的所述第二颗粒类型的颗粒（6）以使得所述第一颗粒类型的颗粒（5）和所述第一颗粒类型的颗粒（6） 第二粒子类型存在于至少一个场笼（1'，1'）中。 本发明还涉及相应的微流体系统。

    ELECTRIC FIELD CAGE AND ASSOCIATED OPERATING METHOD
    10.
    发明申请
    ELECTRIC FIELD CAGE AND ASSOCIATED OPERATING METHOD 审中-公开
    电场笼及相关操作方法

    公开(公告)号：US20100155246A1

    公开(公告)日：2010-06-24

    申请号：US12161062

    申请日：2007-01-17

    申请人： Thomas Schnelle ,  Torsten Müller

    发明人： Thomas Schnelle ,  Torsten Müller

    IPC分类号： B01D57/02

    CPC分类号： B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0645 ,  B01L2400/0415 ,  B01L2400/0424 ,  B03C5/005 ,  B03C5/026

    摘要： The invention relates to an electric field cage (6) for spatially fixing particles (2, 3) which are suspended in a carrier liquid, in particular in a microfluidic system, including a plurality of cage electrodes (7, 8), which can be electrically driven, for generating a capture field. It is proposed that at least one of the cage electrodes (8) is annular and surrounds the other cage electrode (7). The invention also covers an associated operating method.

    摘要翻译： 本发明涉及用于空间固定颗粒（2,3）的电场笼（6），其悬浮在载体液体中，特别是在包括多个笼电极（7,8）的微流体系统中，其可以是 电驱动，用于产生捕获场。 提出至少一个保持架电极（8）是环形的并且围绕着另一个笼状电极（7）。 本发明还涵盖相关的操作方法。