中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

11 records (took 0.02 seconds)

    Optical analyzing device
    1.
    发明授权
    Optical analyzing device 有权

    公开(公告)号：US10739260B2

    公开(公告)日：2020-08-11

    申请号：US15542447

    申请日：2015-01-26

    Applicant: Hitachi High-Technologies Corporation

    Inventor： Takayuki Obara ,  Muneo Maeshima ,  Kazumichi Imai ,  Yohei Hanazaki

    IPC: G01N21/552 ,  G01N1/38

    Abstract: This optical analyzing device is provided with a light source, a detector, a substrate having a metal film on at least one surface thereof, and an optical element for introducing a light beam from the light source to the substrate and delivering the light beam from the substrate toward the detector. A plurality of sample regions for holding samples are provided on the metal film; and a portion of the light beam from the light source is irradiated to any one of the sample regions, is reflected, at least once, by the surface of the substrate on the opposite side of the side on which the sample regions are provided, and is not irradiated to a sample region other than the aforementioned sample region in the path thereof until the portion of the light beam is delivered by the optical element.

    Cell concentration adjustment device, and automatic subculture system using same
    2.
    发明授权
    Cell concentration adjustment device, and automatic subculture system using same 有权

    公开(公告)号：US10138456B2

    公开(公告)日：2018-11-27

    申请号：US15327208

    申请日：2015-07-08

    Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

    Inventor： Akihiro Shimase ,  Kazumichi Imai ,  Sadamitsu Aso ,  Eiichiro Takada ,  Masako Kawarai ,  Toshinari Sakurai

    IPC: C12M1/00 ,  C12M3/00 ,  C12M1/34 ,  C12M1/02 ,  C12M1/36 ,  C12Q1/06

    Abstract: A device which automatically performs a step in which expanded and cultured cells are diluted to a desired cell concentration and re-inoculated using a cell-concentration adjustment device having an inlet for taking in a cell suspension; an outlet for discharging a diluted cell suspension; and a flow path which is provided between the inlet and the outlet and is capable of holding a cell suspension, the flow path being provided with: a liquid delivery pump for causing a cell suspension inside to flow; a cell-concentration measurement instrument for collecting data related to a cell concentration per unit amount of the cell suspension; and a dilution-liquid container for holding a dilution liquid which is supplied to the flow path to dilute the cell suspension. The device further includes a control unit for controlling at least the liquid delivery pump on the basis of the data obtained by the cell-concentration measurement instrument, wherein the control unit determines, on the basis of the data obtained by the cell-concentration measurement instrument, an amount of the dilution liquid required to bring the cell concentration to the desired concentration, and drives the liquid delivery pump so as to take in the required amount of the dilution liquid into the flow path and mix the cell suspension and the dilution liquid.

    IMMUNOANALYSIS METHOD AND IMMUNOANALYSIS DEVICE
    3.
    发明申请
    IMMUNOANALYSIS METHOD AND IMMUNOANALYSIS DEVICE 有权
    免疫分析方法和免疫分析装置

    公开(公告)号：US20150212082A1

    公开(公告)日：2015-07-30

    申请号：US14418990

    申请日：2013-06-21

    Applicant: Hitachi High-Technologies Corporation

    Inventor： Kyoko Imai ,  Toshiro Saito ,  Kazumichi Imai

    IPC: G01N33/543

    CPC classification number: G01N33/54386 ,  G01N21/6428 ,  G01N21/6452 ,  G01N33/54326 ,  G01N33/54366

    Abstract: An object of the present invention is to provide a highly sensitive immunoanalysis method and analysis apparatus. The invention relates to an analysis method and an analysis apparatus which are constituted in such a way that a component to be measured is reacted with capture component specifically reacting thereto and the reactant is labeled when the component to be measured is present and which are characterized by analyzing the component to be measured with single-molecule sensitivity and resolution by arranging the labeled reactant in a spatially separated certain position and detecting the label of the labeled reactant.

    Abstract translation: 本发明的目的是提供高灵敏度的免疫分析方法和分析装置。 本发明涉及一种分析方法和分析装置，其以被测量成分与与其特异性反应的捕获成分反应，并且当待测量成分存在时，反应物被标记，并且其特征在于 通过将标记的反应物排列在空间上分离的某些位置并检测标记的反应物的标记物来分析单分子灵敏度和分辨率的待测组分。

    Cell culture device
    6.
    发明授权
    Cell culture device 有权

    公开(公告)号：US10266801B2

    公开(公告)日：2019-04-23

    申请号：US15106945

    申请日：2014-12-24

    Applicant: Hitachi High-Technologies Corporation

    Inventor： Akihiro Shimase ,  Kazumichi Imai ,  Eiichiro Takada ,  Sadamitsu Aso

    IPC: C12M1/00 ,  C12M3/06

    Abstract: According to the present invention, a simple structure can be used to achieve reliable liquid delivery with no residual air, and simple attachment/detachment of a culture vessel, and thus a closed-system cell culture device exhibiting high reliability can be constructed at low cost. In the present invention, a liquid is supplied or discharged while a culture vessel is in an inclined state. The culture vessel is provided with two flow paths, namely an intake flow path and a discharge flow path, which connect a culture chamber and a connection member. Points where the flow paths join with the culture chamber are respectively configured as an intake port and a discharge port. The discharge port is provided in the position nearest to the axis of inclination of the culture vessel. The intake port is provided in a plane projected from a vertical plane including the aforementioned axis of inclination.

    BIOMOLECULE DETECTION METHOD, BIOMOLECULE DETECTION DEVICE AND ANALYSIS DEVICE
    9.
    发明申请
    BIOMOLECULE DETECTION METHOD, BIOMOLECULE DETECTION DEVICE AND ANALYSIS DEVICE 有权
    生物分子检测方法，生物分子检测装置和分析装置

    公开(公告)号：US20150308977A1

    公开(公告)日：2015-10-29

    申请号：US14418480

    申请日：2013-06-28

    Applicant: Hitachi High-Technologies Corporation

    Inventor： Toshiro Saito ,  Kenta Imai ,  Kyoko Imai ,  Kazumichi Imai ,  Itaru Yanagi ,  Yoshimitsu Yanagawa ,  Masahiko Ando ,  Naoshi Itabashi

    IPC: G01N27/414 ,  G01N33/543

    CPC classification number: G01N27/4145 ,  G01N27/4148 ,  G01N33/48721 ,  G01N33/543 ,  G01N33/54306 ,  G01N37/00

    Abstract: The present invention is intended to provide a method and a device for detecting a biomolecule with high sensitivity and high throughput over a wide dynamic range without requiring concentration adjustments of a sample in advance. The present invention specifically binds charge carriers to a detection target biomolecule, and detects the detection target biomolecule one by one by measuring a current change that occurs as the conjugate of the biomolecule and the charge carriers passes through a micropore. High-throughput detection of a biomolecule sample is possible with an array of detectors.

    Abstract translation: 本发明旨在提供一种用于在宽动态范围内检测具有高灵敏度和高产量的生物分子的方法和装置，而不需要预先对样品进行浓度调节。 本发明将电荷载体特异性地结合到检测目标生物分子，并且通过测量随着生物分子和电荷载体的共轭体通过微孔而发生的电流变化逐个检测检测目标生物分子。 生物分子样品的高通量检测是可能的与一组检测器。

Patent Agency Ranking