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    NUCLEIC ACID SEQUENCING BY ELECTROCHEMICAL DETECTION
    2.
    发明申请
    NUCLEIC ACID SEQUENCING BY ELECTROCHEMICAL DETECTION 有权
    通过电化学检测进行核酸序列测序

    公开(公告)号：US20140238859A1

    公开(公告)日：2014-08-28

    申请号：US14237328

    申请日：2012-08-03

    申请人： Jeffrey Huff ,  Graham Davis ,  Mark Hayden ,  David J. Ecker ,  Dan Wang ,  Gordon Bruce Collier

    发明人： Jeffrey Huff ,  Graham Davis ,  Mark Hayden ,  David J. Ecker ,  Dan Wang ,  Gordon Bruce Collier

    IPC分类号： C12Q1/68 ,  G01N27/447

    CPC分类号： C12Q1/6869 ,  G01N27/3275 ,  G01N27/333 ,  G01N27/447 ,  G01N27/44756 ,  Y02A50/59 ,  Y02A50/60 ,  C12Q2565/607 ,  C12Q2563/113 ,  C12Q2563/116

    摘要： Provided herein is technology relating to sequencing nucleic acids and particularly, but not exclusively, to devices, methods, and systems for sequencing-by-synthesis using changes in pH to monitor base addition. In some embodiments the electrochemical hydrogen ion sensor is a microfabricated mixed metal oxide electrode and in some embodiments the electrochemical hydrogen ion sensor is a membrane electrode. Moreover, in some embodiments the device further comprises a reference electrode. Performing the sequencing reaction involves moving solutions and other fluids (e.g., samples, nucleotide solutions, wash solutions) into and out of the reaction vessel. Thus, in some embodiments, the device further comprises a tube or other transport mechanism or pathway attached to the reaction vessel.

    摘要翻译： 本文提供了与测序核酸有关的技术，特别但并非排他地涉及使用pH变化监测碱添加的用于按合成顺序进行测序的装置，方法和系统。 在一些实施方案中，电化学氢离子传感器是微制造的混合金属氧化物电极，并且在一些实施方案中，电化学氢离子传感器是膜电极。 此外，在一些实施例中，该装置还包括参考电极。 执行测序反应包括将溶液和其它流体（例如，样品，核苷酸溶液，洗涤溶液）移入和移出反应容器。 因此，在一些实施例中，该装置还包括连接到反应容器的管或其它输送机构或通路。

    Headphone
    9.
    外观设计
    Headphone 有权

    公开(公告)号：USD1022950S1

    公开(公告)日：2024-04-16

    申请号：US29850157

    申请日：2022-08-17

    申请人： Dan Wang

    设计人： Dan Wang

    摘要： FIG. 1 is a bottom view of a headphone, showing my new design;
    FIG. 2 is a bottom perspective view thereof;
    FIG. 3 is a top perspective view thereof;
    FIG. 4 is a rear view thereof;
    FIG. 5 is a front view thereof;
    FIG. 6 is a left side view thereof;
    FIG. 7 is a right side view thereof; and,
    FIG. 8 is a top view thereof.
    The broken lines depict portions of the headphones that form no part of the claimed design.

    Single-cylinder single-claw double-card punching machine
    10.
    发明授权
    Single-cylinder single-claw double-card punching machine 有权

    公开(公告)号：US09902515B2

    公开(公告)日：2018-02-27

    申请号：US14372613

    申请日：2012-04-28

    申请人： Qiuming Tang ,  Shujun Ren ,  Dan Wang ,  Chunbing Lv

    发明人： Qiuming Tang ,  Shujun Ren ,  Dan Wang ,  Chunbing Lv

    IPC分类号： B25B3/00 ,  B65B51/05 ,  A22C11/12

    CPC分类号： B65B51/05 ,  A22C11/125 ,  Y10T29/53783

    摘要： A single-cylinder single-claw double-card punching machine, including an air cylinder; the working end face of the air cylinder is connected to a connecting frame; a gantry moving frame is disposed in the middle of the lower part of the connecting frame in an interleaved manner; a piston rob of the air cylinder passes through the connecting frame to connect with the gantry moving frame; both sides of the connecting frame are provided with snap action moving device; a retaining clamp and a folding clamp are disposed at the bottom of the connecting frame; and a card-pushing sheet and a cutter are disposed under the gantry moving frame. The card punching speed of the single-cylinder single-claw double-card pneumatic punching machine is as high as 166 times per minute, with high efficiency and energy savings.