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    Production method of oil or fat containing polyunsaturated fatty acid-containing triglyceride
    1.
    发明授权
    Production method of oil or fat containing polyunsaturated fatty acid-containing triglyceride 有权
    含有多不饱和脂肪酸的甘油三酸酯的油脂的生产方法

    公开(公告)号：US07538238B2

    公开(公告)日：2009-05-26

    申请号：US10482373

    申请日：2002-07-02

    申请人： Kengo Akimoto ,  Motoo Sumida ,  Kenichi Higashiyama ,  Shigeaki Fujikawa

    发明人： Kengo Akimoto ,  Motoo Sumida ,  Kenichi Higashiyama ,  Shigeaki Fujikawa

    IPC分类号： A23D9/00

    CPC分类号： C12P7/6472 ,  A23C9/1528 ,  A23C11/04 ,  A23K20/158 ,  A23L33/115 ,  A23L33/12 ,  C11C3/08 ,  C11C3/10

    摘要： The present invention relates to a production method of an oil containing triglyceride in which medium chain fatty acids are bound to the 1- and 3-positions of the triglyceride and polyunsaturated fatty acid is bound to the 2 position by allowing lipase, which specifically acts on ester bonds at the 1- and 3-positions that has been immobilized on a porous ion exchange resin support having a pore size of about 100 Angstroms or more, to act on a mixture of medium-chain fatty acids and raw material oil containing at least one polyunsaturated fatty acid selected from the group consisting of ω6 series polyunsaturated fatty acid having 18 or more carbon atoms and 3 or more double bonds and ω9 series polyunsaturated fatty acid having 18 or more carbon atoms and 2 or more double bonds, but not containing ω3 series polyunsaturated fatty acid, oils and fats or triglycerides obtained by that method, and the use of the oils and fats or triglycerides in a food, beverage or pharmaceutical composition.

    摘要翻译： 本发明涉及含有甘油三酯的油的制备方法，其中中链脂肪酸与甘油三酯的1位和3位结合，多不饱和脂肪酸通过使脂肪酶特异性地作用于2位而结合到2位上 在固定在孔径为约100埃以上的多孔离子交换树脂载体上的1-位和3-位的酯键作用于中链脂肪酸和至少含有至少 一种选自具有18个或更多个碳原子的ω-6系多不饱和脂肪酸和3个或更多个双键的多不饱和脂肪酸和具有18个或更多个碳原子和2个或更多个双键但不含ω3的ω-系列多不饱和脂肪酸 系列多不饱和脂肪酸，通过该方法获得的油和脂肪或甘油三酯，以及在食品，饮料或药物中使用油和脂肪或甘油三酸酯 l组成。

    Production method of oil or fat containing polyunsaturated fatty acid-containing triglyceride
    2.
    发明授权
    Production method of oil or fat containing polyunsaturated fatty acid-containing triglyceride 有权
    含有多不饱和脂肪酸的甘油三酸酯的油脂的生产方法

    公开(公告)号：US07767427B2

    公开(公告)日：2010-08-03

    申请号：US12232851

    申请日：2008-09-25

    申请人： Kengo Akimoto ,  Motoo Sumida ,  Kenichi Higashiyama ,  Shigeaki Fujikawa

    发明人： Kengo Akimoto ,  Motoo Sumida ,  Kenichi Higashiyama ,  Shigeaki Fujikawa

    IPC分类号： C12P7/64

    CPC分类号： C12P7/6472 ,  A23C9/1528 ,  A23C11/04 ,  A23K20/158 ,  A23L33/115 ,  A23L33/12 ,  C11C3/08 ,  C11C3/10

    摘要： The present invention relates to a production method of an oil containing triglyceride in which medium chain fatty acids are bound to the 1- and 3-positions of the triglyceride and polyunsaturated fatty acid is bound to the 2 position by allowing lipase, which specifically acts on ester bonds at the 1- and 3-positions that has been immobilized on a porous ion exchange resin support having a pore size of about 100 Angstroms or more, to act on a mixture of medium-chain fatty acids and raw material oil containing at least one polyunsaturated fatty acid selected from the group consisting of ω6 series polyunsaturated fatty acid having 18 or more carbon atoms and 3 or more double bonds and ω9 series polyunsaturated fatty acid having 18 or more carbon atoms and 2 or more double bonds, but not containing ω3 series polyunsaturated fatty acid, oils and fats or triglycerides obtained by that method, and the use of the oils and fats or triglycerides in a food, beverage or pharmaceutical composition.

    摘要翻译： 本发明涉及含有甘油三酯的油的制备方法，其中中链脂肪酸与甘油三酯的1位和3位结合，多不饱和脂肪酸通过使脂肪酶特异性地作用于2位而结合到2位上 在已经固定在孔径为约100埃以上的多孔离子交换树脂载体上的1-位和3-位的酯键作用于至少含有至少含有中链脂肪酸和原料油的混合物 一种选自具有18个或更多个碳原子的ω6系多不饱和脂肪酸和3个或更多个双键的多不饱和脂肪酸和具有18个以上碳原子和2个以上双键但不含ω3的ω9系多不饱和脂肪酸 系列多不饱和脂肪酸，通过该方法获得的油和脂肪或甘油三酯，以及在食品，饮料或药物组合物中使用油和脂肪或甘油三酸酯 。

    Triglyceride and composition comprising the same
    4.
    发明授权
    Triglyceride and composition comprising the same 有权
    甘油三酸酯及其组合物

    公开(公告)号：US06248909B1

    公开(公告)日：2001-06-19

    申请号：US09335730

    申请日：1999-06-18

    申请人： Kengo Akimoto ,  Toshiaki Yaguchi ,  Shigeaki Fujikawa

    发明人： Kengo Akimoto ,  Toshiaki Yaguchi ,  Shigeaki Fujikawa

    IPC分类号： C07C5700

    CPC分类号： C07C69/587 ,  A23D9/00 ,  A23K20/158 ,  A23L33/115 ,  C11C3/10 ,  Y10S426/807

    摘要： The present invention provides a novel triglyceride and a composition containing that novel triglyceride having a triglyceride structure of the human breast milk type, which triglyceride has a saturated fatty acid having 16-18 carbon atoms at the position 2, at the position 1 and/or 3; which is and at least one &ohgr;6, &ohgr;9 or &ohgr;3 unsaturated fatty acid manufactured by subjecting a glyceride in which a saturated fatty acid having 16 to 18 carbon atoms is bonded at position 2 to transesterification using a lipase and a &ohgr;6, &ohgr;9 or &ohgr;3-unsaturated fatty acid.

    摘要翻译： 本发明提供一种新颖的甘油三酸酯和含有具有人母乳型甘油三酯结构的新型甘油三酯的组合物，该甘油三酸酯在位置2具有16-18个碳原子的饱和脂肪酸，位置1和/或 3; 其是通过使其中在位置2处键合具有16至18个碳原子的饱和脂肪酸的甘油酯使用脂肪酶和ω6，ω9或ω3-不饱和脂肪酸进行酯交换而制备的至少一种ω6，ω9或ω3不饱和脂肪酸 脂肪酸。

    OLIGOSACCHARIDES DERIVED FROM FUCOIDAN
    6.
    发明申请
    OLIGOSACCHARIDES DERIVED FROM FUCOIDAN 审中-公开
    来自FUCOIDAN的OLIGOSACCHARIDES

    公开(公告)号：US20100113390A1

    公开(公告)日：2010-05-06

    申请号：US12524414

    申请日：2007-01-26

    申请人： Shigeaki Fujikawa ,  Yuko Fukui ,  Hiroshi Watanabe ,  Yuji Nonaka ,  Takeshi Yasumoto ,  Hideo Naoki

    发明人： Shigeaki Fujikawa ,  Yuko Fukui ,  Hiroshi Watanabe ,  Yuji Nonaka ,  Takeshi Yasumoto ,  Hideo Naoki

    IPC分类号： A61K31/715 ,  C07H3/04 ,  C07H3/06 ,  C07H5/10 ,  A61P3/04

    CPC分类号： C07H11/00 ,  A23L33/10 ,  A23V2002/00 ,  A61K8/60 ,  A61K2800/782 ,  A61Q5/02 ,  A61Q19/00 ,  C07H7/033 ,  C07H13/06 ,  A23V2200/326 ,  A23V2200/332 ,  A23V2250/50 ,  A23V2250/28

    摘要： The present invention provides a fucoidan-derived low molecular weight compound with a good quality of taste, which has a specified structure and function and is free from problems in absorption, antigenicity, uniformity, an anticoagulant activity and so on, which problems arise when developing fucoidan, a sulfated polysaccharide having an extremely large molecular weight, as drugs or health foods. As a result of analyzing low molecular weight compounds obtained by acid hydrolysis of fucoidan, the inventors have identified fucoidan oligosaccharides (I) to (XI). Further, these oligosaccharides have been found to have anti-obesity and/or blood glucose elevation suppressing effects through inhibition of carbohydrate and/or lipid absorption as a result of α-glucosidase inhibition and/or lipase inhibition.

    摘要翻译： 本发明提供具有优良品质的岩藻依聚糖衍生的低分子量化合物，其具有特定的结构和功能，并且不存在吸收，抗原性，均匀性，抗凝血活性等问题，当发展时出现问题 岩藻依聚糖，分子量极大的硫酸化多糖作为药物或保健食品。 通过分析由岩藻依聚糖酸水解获得的低分子量化合物的结果，本发明人鉴定了岩藻依聚糖寡糖（I）至（XI）。 此外，已经发现这些寡糖通过由于α-葡糖苷酶抑制和/或脂肪酶抑制而抑制碳水化合物和/或脂质吸收而具有抗肥胖和/或血糖升高抑制作用。

    Skin preparations for external use
    8.
    发明授权
    Skin preparations for external use 失效
    外用皮肤准备

    公开(公告)号：US5660838A

    公开(公告)日：1997-08-26

    申请号：US394201

    申请日：1995-02-24

    申请人： Kunimasa Koga ,  Takumi Kobayashi ,  Shigeaki Fujikawa ,  Masako Sawada

    发明人： Kunimasa Koga ,  Takumi Kobayashi ,  Shigeaki Fujikawa ,  Masako Sawada

    IPC分类号： C07H3/04 ,  A61K8/00 ,  A61K8/60 ,  A61K8/73 ,  A61K9/06 ,  A61K31/00 ,  A61K31/70 ,  A61K31/7016 ,  A61P17/00 ,  A61Q5/02 ,  A61Q19/00 ,  A61K7/06 ,  A61K7/48

    CPC分类号： A61Q19/00 ,  A61K31/70 ,  A61K8/60 ,  A61Q19/007 ,  A61Q5/02 ,  A61Q19/001 ,  Y10S514/873

    摘要： Xylobiose-containing skin preparations for external use are disclosed. Skin preparations for external use into which xylobiose may be incorporated include cosmetics such as clear lotions, milky lotions, packs and lip treatments, drugs or quasidrugs such as ointments and cataplasms, hair-care products such as rinses and hair conditions, and detergents such as hair shampoos and body shampoos. Xylobiose is typically contained in an amount of 0.0001-20 wt %, preferably 0.1-10 wt %, of the total amount of the skin preparation on a dry solids basis. The incorporation of xylobiose is effective not only in preventing the occurrence of stickiness, color change and malodor in the skin preparations but also in providing enhanced moisture retention and reducing excessive roughness and dryness of the skin and hair.

    摘要翻译： 公开了含有二氧化硅的外用皮肤制剂。 可以掺入木二糖的外用皮肤制剂包括化妆品如透明乳液，乳液，包装和唇部处理，药物或准药如软膏和粘膜，护发产品如漂洗剂和毛发条件，以及洗涤剂如 头发洗发水和身体洗发水。 皮质制剂的总量通常以干固体计为0.0001-20重量％，优选0.1-10重量％。 结合木二糖不仅有效防止皮肤制剂中的粘着性，变色和恶臭的发生，而且在提供增强的保湿性和减少皮肤和头发的过度粗糙和干燥方面是有效的。