利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

22 条记录 (耗时 0.025 秒)

    Catechol functionalized polymers and method for preparing them
    1.
    发明授权
    Catechol functionalized polymers and method for preparing them 有权
    儿茶酚官能化聚合物及其制备方法

    公开(公告)号：US08568872B2

    公开(公告)日：2013-10-29

    申请号：US12064564

    申请日：2005-08-24

    申请人： Marcus Textor ,  Stefan Zürcher ,  Karl Gademann ,  Samuele Tosatti

    发明人： Marcus Textor ,  Stefan Zürcher ,  Karl Gademann ,  Samuele Tosatti

    IPC分类号： B32B3/00

    CPC分类号： C08G65/3315 ,  A61K47/60 ,  C08G65/329 ,  Y10T428/265 ,  Y10T428/31511 ,  Y10T428/31663 ,  Y10T428/31725 ,  Y10T428/31855

    摘要： Described are compounds that are capable of forming adlayers, the compounds comprising at least one headgroup A, an optional linker B, a polymer C, a terminal group D and an optional crosslinking group R, wherein the headgroup A is a compound of the following formula wherein X is independently selected from an acidic group, Y is a group derived from a convenient coupling group, Z1, Z3, and Z4 are C or N+ Z2, Z5 and Z6 are C-L1 or N+-L, wherein L1 is H or an electron withdrawing group, L is C1-C6 alkyl, in particular C1-C4 alkyl L2 and L3 are independently selected from H or C1-C6 alkyl, or L2 may form together with L1 or L of Z6 a heterocycle, in particular a positively charged heterocycle, n is 0, or 1, or 2, or 3, m is 0 or 1.

    摘要翻译： 描述的是能够形成附着物的化合物，所述化合物包含至少一个头基A，任选的接头B，聚合物C，末端基团D和任选的交联基团R，其中头基A是下式的化合物 其中X独立地选自酸性基团，Y是衍生自方便偶合基团的基团，Z 1，Z 3和Z 4是C或N + Z 2，Z 5和Z 6是C-L 1或N + -L，其中L 1是H或 吸电子基团，L是C1-C6烷基，特别是C1-C4烷基L2和L3独立地选自H或C1-C6烷基，或L2可以与Z6的L1或L一起形成杂环，特别是正 带电杂环，n为0或1，或2或3，m为0或1。

    Catechol Functionalized Polymers and Method for Preparing Them
    2.
    发明申请
    Catechol Functionalized Polymers and Method for Preparing Them 有权
    儿茶酚官能化聚合物及其制备方法

    公开(公告)号：US20090093610A1

    公开(公告)日：2009-04-09

    申请号：US12064564

    申请日：2005-08-24

    申请人： Marcus Textor ,  Stefan Zurcher ,  Karl Gademann ,  Samuele Tosatti

    发明人： Marcus Textor ,  Stefan Zurcher ,  Karl Gademann ,  Samuele Tosatti

    IPC分类号： C08G73/06

    CPC分类号： C08G65/3315 ,  A61K47/60 ,  C08G65/329 ,  Y10T428/265 ,  Y10T428/31511 ,  Y10T428/31663 ,  Y10T428/31725 ,  Y10T428/31855

    摘要： Described are compounds that are capable of forming adlayers, the compounds comprising at least one headgroup A, an optional linker B, a polymer C, a terminal group D and an optional crosslinking group R, wherein the headgroup A is a compound of the following formula wherein X is independently selected from an acidic group, Y is a group derived from a convenient coupling group, Z1, Z3, and Z4 are C or N+ Z2, Z5 and Z6 are C-L1 or N+-L, wherein L1 is H or an electron withdrawing group, L is C1-C6 alkyl, in particular C1-C4 alkyl L2 and L3 are independently selected from H or C1-C6 alkyl, or L2 may form together with L1 or L of Z6 a heterocycle, in particular a positively charged heterocycle, n is 0, or 1, or 2, or 3, m is 0 or 1.

    摘要翻译： 描述的是能够形成附着物的化合物，所述化合物包含至少一个头基A，任选的接头B，聚合物C，末端基团D和任选的交联基团R，其中头基A是下式的化合物 其中X独立地选自酸性基团，Y是衍生自方便偶合基团的基团，Z 1，Z 3和Z 4是C或N + Z 2，Z 5和Z 6是C-L 1或N + -L，其中L 1是H或 吸电子基团，L是C1-C6烷基，特别是C1-C4烷基L2和L3独立地选自H或C1-C6烷基，或L2可以与Z6的L1或L一起形成杂环，特别是正 带电杂环，n为0或1，或2或3，m为0或1。

    Multifunctional polymeric surface coatings in analytic and sensor devices
    8.
    发明授权
    Multifunctional polymeric surface coatings in analytic and sensor devices 有权
    分析和传感器设备中的多功能聚合物表面涂层

    公开(公告)号：US06884628B2

    公开(公告)日：2005-04-26

    申请号：US09560472

    申请日：2000-04-28

    申请人： Jeffrey A. Hubbell ,  Marcus Textor ,  Donald L. Elbert ,  Stephanie Finken ,  Rolf Hofer ,  Nicholas D. Spencer ,  Laurence Ruiz-Taylor

    发明人： Jeffrey A. Hubbell ,  Marcus Textor ,  Donald L. Elbert ,  Stephanie Finken ,  Rolf Hofer ,  Nicholas D. Spencer ,  Laurence Ruiz-Taylor

    IPC分类号： A61L27/34 ,  A61L31/10 ,  G01N33/543 ,  G01N33/551 ,  G01N33/53

    CPC分类号： B82Y30/00 ,  A61B5/14546 ,  A61B5/1459 ,  A61L27/34 ,  A61L31/10 ,  G01N33/54373 ,  G01N33/54393 ,  G01N33/551 ,  Y10S435/815 ,  Y10S435/961 ,  Y10S435/969 ,  Y10S436/819 ,  Y10S436/823

    摘要： Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non-specific interaction, adsorption or attachment of molecular or ionic components present in an analyte solution. Chemical, biochemical or biological groups that are able to recognize, interact with and bind specifically to target molecules in the material containing the analyte to be detected can be coupled to, integrated into, or absorbed to the multifunctional copolymers. These multifunctional copolymer coatings are compatible with a variety of different established methods to detect, sense and quantify the target molecule in an analyte. The multifunctional copolymer coatings typically include brush copolymers based on a polycationic or polyanionic (jointly referred to herein as ‘polyionic’) backbone with side chains that control interaction with the environment, such as poly(ethylene glycol) or poly(ethylene oxide)-based side chains that decrease cellular adhesion, and analyte-specific side chains. They can be used to pattern the surfaces into non-adhesive and specifically adhesive areas by applications of known techniques such as microfluidic or contact printing techniques.

    摘要翻译： 具有分子结构和针对特定应用优化的性能的多功能聚异戊二烯共聚物在/或应用于基材表面进行合成，用于分析和感测目的。 涂层对于抑制分析物溶液中存在的分子或离子组分的非特异性相互作用，吸附或附着是特别有用的。 能够识别，相互作用并且特异性结合含有待检测分析物的物质中的靶分子的化学，生物化学或生物学基团可与多功能共聚物偶联，整合或吸收。 这些多功能共聚物涂层与各种不同的已知方法兼容，以检测，感测和定量分析物中的目标分子。 多功能共聚物涂层通常包括基于聚阳离子或聚阴离子（共同称为“聚阴离子”）骨架的刷共聚物，侧链具有控制与环境相互作用的侧链，例如聚（乙二醇）或聚（环氧乙烷） 减少细胞粘附的侧链和分析物特异性侧链。 它们可用于通过已知技术如微流体或接触印刷技术的应用将表面图案化成非粘合性和特异性粘合剂区域。