公开(公告)号：US10203275B2

公开(公告)日：2019-02-12

申请号：US13204415

申请日：2011-08-05

申请人： David Herzog ,  Zhizhou Wang ,  Stephen C. Wardlaw ,  Min Xie

发明人： David Herzog ,  Zhizhou Wang ,  Stephen C. Wardlaw ,  Min Xie

IPC分类号： G01N15/14 ,  G01N21/59 ,  G01N21/64 ,  G01N33/50 ,  G01N33/49 ,  G01N15/00

摘要： A method and apparatus for identifying one or more target constituents (e.g., white blood cells) within a biological sample is provided. The method includes the steps of: a) adding at least one colorant to the sample; b) disposing the sample into a chamber defined by at least one transparent panel; c) creating at least one image of the sample quiescently residing within the chamber; d) identifying target constituents within the sample image; e) quantitatively analyzing at least some of the identified target constituents within the image relative to one or more predetermined quantitatively determinable features; and f) identifying at least one type of target constituent within the identified target constituents using the quantitatively determinable features.

公开(公告)号：US20120263369A1

公开(公告)日：2012-10-18

申请号：US13087037

申请日：2011-04-14

申请人： Min Xie ,  Zhizhou Wang

发明人： Min Xie ,  Zhizhou Wang

IPC分类号： G06K9/00

CPC分类号： G06T7/0012 ,  G06K9/00147 ,  G06T2207/10024 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30024 ,  G06T2207/30242 ,  H04N19/102 ,  H04N19/167 ,  H04N19/17

摘要： A method and apparatus for analyzing white blood cells (WBCs) within a whole blood sample quiescently residing within a chamber is provided. The chamber is defined by at least one transparent panel, and the whole blood sample includes at least one colorant operable to differentially identify at least one WBC type from another WBC type within the sample. The method includes the steps of: a) creating at least one image of the sample quiescently residing within the chamber; b) identifying portions of the sample image, with each portion representing a single WBC; c) compressing the sample image portions using a first compression algorithm; and d) one of compressing a remainder of the sample image not included in the portions using a second compression algorithm, or discarding the remainder.

摘要翻译： 提供了一种用于分析静止在室内的全血样品中的白细胞（WBC）的方法和装置。 所述腔室由至少一个透明面板限定，并且全血样品包括至少一种着色剂，其可操作以从样品内的另一种WBC类型差异鉴定至少一种WBC类型。 该方法包括以下步骤：a）创建静止在室内的样品的至少一个图像; b）识别样本图像的部分，每个部分表示单个WBC; c）使用第一压缩算法对样本图像部分进行压缩; 以及d）使用第二压缩算法压缩未包括在部分中的样本图像的剩余部分之一，或者舍弃余数。

公开(公告)号：US20110164803A1

公开(公告)日：2011-07-07

申请号：US12982422

申请日：2010-12-30

申请人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

发明人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

IPC分类号： G06K9/00

CPC分类号： G01N33/49

摘要： A method and apparatus for determining a cell volume of a red blood cell is provided. The method includes the steps of: a) depositing a sample into an analysis chamber, the chamber defined by an first panel interior surface, a second panel interior surface, and a known or determinable height, which height is such that at least one red blood cell subject to a sphering agent assumes a partially compressed spherical shape in contact with the interior surfaces; b) imaging the at least one partially compressed spherical red blood cell contacting the interior surfaces, and producing image signals; c) determining a radius of the partially compressed spherical red blood cell from the image signals; and d) determining a volume of the imaged red blood cell using the determined radius.

摘要翻译： 提供了一种用于确定红细胞的细胞体积的方法和装置。 该方法包括以下步骤：a）将样品沉积到分析室中，所述室由第一面板内表面，第二面板内表面和已知或可确定的高度限定，所述高度使得至少一个红血 经受球形剂的细胞呈现与内表面接触的部分压缩球形; b）对与内表面接触的至少一个部分压缩的球形红细胞进行成像，并产生图像信号; c）根据图像信号确定部分压缩的球形红细胞的半径; 以及d）使用确定的半径来确定成像的红细胞的体积。

公开(公告)号：US20120034647A1

公开(公告)日：2012-02-09

申请号：US13204415

申请日：2011-08-05

申请人： David Herzog ,  Zhizhou Wang ,  Stephen C. Wardlaw ,  Min Xie

发明人： David Herzog ,  Zhizhou Wang ,  Stephen C. Wardlaw ,  Min Xie

IPC分类号： C12Q1/04 ,  C12M1/34

CPC分类号： G01N15/1475 ,  G01N21/5907 ,  G01N21/6458 ,  G01N33/49 ,  G01N33/5094 ,  G01N2015/008

摘要： A method and apparatus for identifying one or more target constituents (e.g., white blood cells) within a biological sample is provided. The method includes the steps of: a) adding at least one colorant to the sample; b) disposing the sample into a chamber defined by at least one transparent panel; c) creating at least one image of the sample quiescently residing within the chamber; d) identifying target constituents within the sample image; e) quantitatively analyzing at least some of the identified target constituents within the image relative to one or more predetermined quantitatively determinable features; and f) identifying at least one type of target constituent within the identified target constituents using the quantitatively determinable features.

摘要翻译： 提供了用于识别生物样品内的一种或多种靶组分（例如白细胞）的方法和装置。 该方法包括以下步骤：a）向样品中加入至少一种着色剂; b）将样品放置在由至少一个透明板限定的室中; c）产生静止在室内的样品的至少一个图像; d）识别样本图像中的目标成分; e）相对于一个或多个预定的可定量确定的特征定量地分析图像内的所识别的目标成分中的至少一些; 以及f）使用所述可定量确定的特征来识别所识别的目标成分内的至少一种类型的目标成分。

公开(公告)号：US09064301B2

公开(公告)日：2015-06-23

申请号：US13087037

申请日：2011-04-14

申请人： Min Xie ,  Zhizhou Wang

发明人： Min Xie ,  Zhizhou Wang

IPC分类号： G06K9/00 ,  G06T7/00 ,  H04N19/102 ,  H04N19/167 ,  H04N19/17

CPC分类号： G06T7/0012 ,  G06K9/00147 ,  G06T2207/10024 ,  G06T2207/10056 ,  G06T2207/10064 ,  G06T2207/30024 ,  G06T2207/30242 ,  H04N19/102 ,  H04N19/167 ,  H04N19/17

摘要： A method and apparatus for analyzing white blood cells (WBCs) within a whole blood sample quiescently residing within a chamber is provided. The chamber is defined by at least one transparent panel, and the whole blood sample includes at least one colorant operable to differentially identify at least one WBC type from another WBC type within the sample. The method includes the steps of: a) creating at least one image of the sample quiescently residing within the chamber; b) identifying portions of the sample image, with each portion representing a single WBC; c) compressing the sample image portions using a first compression algorithm; and d) one of compressing a remainder of the sample image not included in the portions using a second compression algorithm, or discarding the remainder.

摘要翻译： 提供了一种用于分析静止在室内的全血样品中的白细胞（WBC）的方法和装置。 所述腔室由至少一个透明面板限定，并且全血样品包括至少一种着色剂，其可操作以从样品内的另一种WBC类型差异鉴定至少一种WBC类型。 该方法包括以下步骤：a）创建静止在室内的样品的至少一个图像; b）识别样本图像的部分，每个部分表示单个WBC; c）使用第一压缩算法对样本图像部分进行压缩; 以及d）使用第二压缩算法压缩未包括在部分中的样本图像的剩余部分之一，或者舍弃余数。

公开(公告)号：US08837803B2

公开(公告)日：2014-09-16

申请号：US12982422

申请日：2010-12-30

申请人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

发明人： Zhizhou Wang ,  Min Xie ,  Anil Patil ,  Chong Chen ,  Shaohong Wang ,  Cord Mueller

IPC分类号： G06K9/00 ,  G01N33/49

CPC分类号： G01N33/49

摘要： A method and apparatus for determining a cell volume of a red blood cell is provided. The method includes the steps of: a) depositing a sample into an analysis chamber, the chamber defined by an first panel interior surface, a second panel interior surface, and a known or determinable height, which height is such that at least one red blood cell subject to a sphering agent assumes a partially compressed spherical shape in contact with the interior surfaces; b) imaging the at least one partially compressed spherical red blood cell contacting the interior surfaces, and producing image signals; c) determining a radius of the partially compressed spherical red blood cell from the image signals; and d) determining a volume of the imaged red blood cell using the determined radius.

摘要翻译： 提供了一种用于确定红细胞的细胞体积的方法和装置。 该方法包括以下步骤：a）将样品沉积到分析室中，所述室由第一面板内表面，第二面板内表面和已知或可确定的高度限定，所述高度使得至少一个红血 经受球形剂的细胞呈现与内表面接触的部分压缩球形; b）对与内表面接触的至少一个部分压缩的球形红细胞进行成像，并产生图像信号; c）根据图像信号确定部分压缩的球形红细胞的半径; 以及d）使用确定的半径来确定成像的红细胞的体积。

公开(公告)号：US07957601B2

公开(公告)日：2011-06-07

申请号：US11788005

申请日：2007-04-18

申请人： Qiang Cheng ,  Michael Pisot ,  Min Xie

发明人： Qiang Cheng ,  Michael Pisot ,  Min Xie

IPC分类号： G06K9/36 ,  G06K9/00

CPC分类号： H04N19/503 ,  H04N19/63

摘要： A system and method for rendering images, and performing operations such as windowing and leveling, when the parameters of a client appliance are known and rendering images when the parameters of a client appliance are unknown. The invention also considers the rendering from the client appliance perspective and the server appliance perspective.

摘要翻译： 当客户端设备的参数是已知的并且当客户端设备的参数是未知的时渲染图像时，用于呈现图像的系统和方法以及执行诸如窗口化和调平的操作。 本发明还考虑从客户端设备的角度和服务器设备的角度进行渲染。

公开(公告)号：US07777742B2

公开(公告)日：2010-08-17

申请号：US11623344

申请日：2007-01-16

申请人： Daqing Xue ,  Min Xie

发明人： Daqing Xue ,  Min Xie

IPC分类号： G06T15/00

CPC分类号： G06T19/20 ,  G06T7/30 ,  G06T2200/04 ,  G06T2207/20016 ,  G06T2207/30004 ,  G06T2219/2021

摘要： A method and system of volume deformation, including accessing a tree structure for a set of deformation maps. The tree structure is traversed for each voxel in an original volume and each voxel is transformed according to each deformation map corresponding to a node of the tree structure until the entire original volume is deformed into reference volume space. Also, a method and system of generating an ordered map tree structure, including identifying a root node of a bounding box, the bounding box being a union of the root node's descendants. Child nodes are identified for each node, the child nodes being ordered so that a left child is applied before a corresponding right child, wherein each child node contains a deformation map and a corresponding bounding box. Each path originating from the root node corresponds to a complete deformation map sequence, and when a portion of two deformation maps overlap, the deformation map having a lower priority is a child of the deformation map having a higher priority.

摘要翻译： 体积变形的方法和系统，包括访问一组变形图的树结构。 对于原始体积中的每个体素遍历树结构，并且根据与树结构的节点对应的每个变形图来变换每个体素，直到整个原始体积变形为参考体积空间。 另外，生成有序映射树结构的方法和系统，包括识别边界框的根节点，边界框是根节点的后代的并集。 为每个节点识别子节点，子节点被排序，以便在相应的右子节点之前应用左子节点，其中每个子节点包含变形图和对应的边界框。 源自根节点的每个路径对应于完整的变形图序列，并且当两个变形图的一部分重叠时，具有较低优先级的变形图是具有较高优先级的变形图的子。

公开(公告)号：US20080044097A1

公开(公告)日：2008-02-21

申请号：US11779459

申请日：2007-07-18

申请人： Smita Krishnan ,  Qiang Cheng ,  Min Xie

发明人： Smita Krishnan ,  Qiang Cheng ,  Min Xie

IPC分类号： G06K9/38

CPC分类号： H04N19/94 ,  H04N19/124

摘要： A system and method provide image data compression and reconstruction technique optimizations that may enhance (1) local gradient quantization, (2) quantized gradient merging, and/or (3) prediction and/or prediction error computations. A data structure may be created before image data compression that provides access to pre-computed quantization values during image data compression. Quantization merging may be performed by a one-to-one mapping of quantization vectors into corresponding quantization values. Subsequently, the sign of the quantization values may be checked to further reduce the number of logical steps required. A prediction technique may alleviate the effect that noise of neighboring pixels has on the current pixel. The optimizations may be applied to a JPEG-LS based algorithm to speed up processing by approximately 50%, while maintaining error controllability and compression ratio. The optimizations may enhance remote rendering and viewing of medical images in a client server environment.

摘要翻译： 系统和方法提供可以增强（1）局部梯度量化，（2）量化梯度合并和/或（3）预测和/或预测误差计算的图像数据压缩和重构技术优化。 可以在图像数据压缩之前创建数据结构，该图像数据压缩在图像数据压缩期间提供对预先计算的量化值的访问。 量化合并可以通过量化矢量的一对一映射到对应的量化值来执行。 随后，可以检查量化值的符号，以进一步减少所需的逻辑步骤的数量。 预测技术可以减轻相邻像素的噪声对当前像素的影响。 优化可以应用于基于JPEG-LS的算法，以加速大约50％的处理，同时保持误差可控性和压缩比。 优化可以增强在客户端服务器环境中远程呈现和查看医学图像。

公开(公告)号：US09149416B1

公开(公告)日：2015-10-06

申请号：US12545771

申请日：2009-08-21

申请人： Min Xie ,  Robin Rudolph ,  Stephanie Ponder

发明人： Min Xie ,  Robin Rudolph ,  Stephanie Ponder

IPC分类号： A61K8/00 ,  C11D1/65 ,  C11D3/43 ,  C11D1/12

CPC分类号： A61K8/00 ,  A01N25/04 ,  A01N31/14 ,  A01N53/00 ,  A61K8/062 ,  A61K8/463 ,  A61K8/4993 ,  A61K8/731 ,  A61K2800/262 ,  A61Q17/02 ,  A61Q19/10 ,  C11D1/12 ,  C11D1/65 ,  C11D3/43 ,  A01N43/40 ,  A01N49/00 ,  A01N25/30

摘要： The present invention provides an insecticidal emulsion cleansing system comprising a clear oil-in-water (o/w) emulsion wherein the oil phase contains an ionic surfactant and an insecticide suspended together as nanometer sized particles in the water phase; and wherein the water phase contains an oppositely charged polymer. The insecticide is preferably a pyrethroid such as a natural pyrethrin or a synthetic pyrethroid. Suitable pyrethroids include pyrethroid esters and pyrethroid ethers.

摘要翻译： 本发明提供一种杀虫乳液清洁系统，其包含透明的水包油（o / w）乳液，其中油相含有离子表面活性剂和在水相中作为纳米尺寸颗粒悬浮在一起的杀虫剂; 并且其中所述水相含有相反电荷的聚合物。 杀虫剂优选为拟除虫菊酯，如天然除虫菊酯或合成拟除虫菊酯。 合适的拟除虫菊酯包括拟除虫菊酯和拟除虫菊酯醚。