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    PRODUCTION METHOD OF ISOXAZOLINE-SUBSTITUTED BENZOIC ACID AMIDE COMPOUND
    6.
    发明申请
    PRODUCTION METHOD OF ISOXAZOLINE-SUBSTITUTED BENZOIC ACID AMIDE COMPOUND 有权
    ISOXAZOLINE-取代苯甲酸酰胺化合物的生产方法

    公开(公告)号：US20130144066A1

    公开(公告)日：2013-06-06

    申请号：US13757045

    申请日：2013-02-01

    申请人： Nissan Chemical Industries, Ltd.

    发明人： Hiroyuki KOUSAKA ,  Shunsuke Fukuya ,  Yuji Moriyama ,  Manabu Yaosaka ,  Takashi Mizukoshi

    IPC分类号： C07D261/04

    CPC分类号： C07D261/04

    摘要： A production method of an isoxazoline-substituted benzoic acid amide compound of Formula (1) where X is a halogen atom, C1-6 haloalkyl, etc., Y is a halogen atom, C1-6 alkyl, etc., R1 is a C1-6 haloalkyl, etc., R2 and R3 independently of each other are a hydrogen atom, C1-6 alkyl, etc., R4 is C1-6 alkyl, C1-6 haloalkyl, etc., R5 is a hydrogen atom, C1-6 alkyl, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, including: reacting an isoxazoline-substituted benzene compound of Formula (3) where X, Y, R1, m, and n are the same as defined above, L is a chlorine atom, a bromine atom, —C(O)OH, —C(O)J, etc., J is a halogen atom, with a 2-aminoacetic acid amide compound of Formula (2) where R2, R3, R4, and R5 are the same as defined above, or a salt thereof; crystal forms and the production method thereof.

    摘要翻译： 其中X是卤素原子，C 1-6卤代烷基等的式（1）的异恶唑啉取代的苯甲酸酰胺化合物的制备方法，Y是卤素原子，C 1-6烷基等，R 1是C 1 -6卤代烷基等，R2和R3彼此独立地是氢原子，C1-6烷基等，R4是C1-6烷基，C1-6卤代烷基等，R5是氢原子，C1- 6烷基等，m为0〜5的整数，n为0〜4的整数，包括：使式（3）的异恶唑啉取代的苯化合物，其中X，Y，R 1，m和n分别为 与上述相同，L是氯原子，溴原子，-C（O）OH，-C（O）J等，J是卤素原子，与式（2）的2-氨基乙酰胺化合物 2）其中R2，R3，R4和R5与上述定义相同，或其盐; 晶体形式及其制备方法。

    Isoxazoline-substituted benzamide compound and pesticide
    7.
    发明授权
    Isoxazoline-substituted benzamide compound and pesticide 有权
    异恶唑啉取代苯甲酰胺化合物和农药

    公开(公告)号：US08987464B2

    公开(公告)日：2015-03-24

    申请号：US14157048

    申请日：2014-01-16

    申请人： Nissan Chemical Industries, Ltd.

    发明人： Takeshi Mita ,  Yuki Furukawa ,  Ken-ichi Toyama ,  Manabu Yaosaka ,  Eitatsu Ikeda ,  Yoshihide Masuzawa ,  Mitsuaki Komoda

    IPC分类号： C07C237/32 ,  C07D213/36 ,  A01N43/80 ,  C07D413/04 ,  C07C237/36 ,  C07D213/75 ,  C07D213/81 ,  C07D237/20 ,  C07D239/42 ,  C07D241/20 ,  C07D401/12

    CPC分类号： C07C237/32 ,  A01N43/80 ,  C07C237/36 ,  C07D213/75 ,  C07D213/81 ,  C07D237/20 ,  C07D239/42 ,  C07D241/20 ,  C07D401/12 ,  C07D413/04

    摘要： An isoxazoline-substituted benzamide compound of formula (1) or a salt thereof: wherein A1, A2 and A3 independently of one another are carbon atom or nitrogen atom, G is benzene ring, etc., W is oxygen atom or sulfur atom, etc., X is halogen atom, C1-C6haloalkyl, etc., Y is halogen atom, C1-C6alkyl, etc., R1 is —CH═NOR1a, —C(O)OR1c, —C(O)NHR1d, phenyl substituted with (Z)p1, D-14, D-52, D-53, D-55 to D-59, etc., R1a is C1-C6alkyl, etc., R1c is C1-C6alkyl, etc., R1d is hydrogen atom, —C(O)R15, —C(O)OR15, etc., R2 is C1-C6alkyl, —CH2R14a, C1-C6alkynyl, —C(O)R15, —C(O)OR15, etc., further when R1 is —CH═NOR1a, —C(O)OR1c or —C(O)N(R1e)R1d, R2 may be hydrogen atom, R3 is C1-C6haloalkyl, etc., R14a is cyano, —OR25, etc., R15 is C1-C6alkyl, C1-C6haloalkyl, C1-C4alkoxy C1-C4alkyl, C1-C4alkylthio C1-C4alkyl, C3-C6cycloalkyl, C2-C6alkenyl, etc., R25 is C1-C4alkyl, C1-C4haloalkyl, —C(O)R32 or —C(O)OR32, etc., R32 is C1-C6alkyl or C3-C6cycloalkyl, etc., Z is halogen atom, cyano, nitro, C1-C6alkyl, C1-C6alkoxy, etc., m is an integer of 0 to 5, n is an integer of 0 to 4, p1 is an integer of 1 to 5. The pesticide containing these compounds.

    摘要翻译： 式（1）的异恶唑啉取代的苯甲酰胺化合物或其盐：其中A1，A2和A3彼此独立地为碳原子或氮原子，G为苯环等，W为氧原子或硫原子等 ，X是卤素原子，C 1 -C 6卤代烷基等，Y是卤素原子，C 1 -C 6烷基等，R 1是-CH = NOOR 1，-C（O）OR 1 c，-C（O）NHR 1d， （Z）p1，D-14，D-52，D-53，D-55〜D-59等，R1a为C1-C6烷基等，R1c为C1-C6烷基等，R1d为氢原子 ，-C（O）R 15，-C（O）OR 15等，R 2是C 1 -C 6烷基，-CH 2 R 14a，C 1 -C 6炔基，-C（O）R 15，-C（O）OR 15等 R1为-CH = NO1a，-C（O）OR1c或-C（O）N（R1e）R1d，R2为氢原子，R3为C1-C6卤代烷基等，R14a为氰基，-OR25等， R 15是C 1 -C 4烷基，C 1 -C 4烷基，C 1 -C 4烷基，C 1 -C 4烷氧基，C 1 -C 4烷基，C 1 -C 4烷硫基C 1 -C 4烷基，C 3 -C 6环烷基，C 2 -C 6链烯基等。 R32或-C（O）OR32等，R32是C1-C6烷基或C3-C6环烷基等，Z是卤素 原子，氰基，硝基，C1-C6烷基，C1-C6烷氧基等，m为0〜5的整数，n为0〜4的整数，p1为1〜5的整数，含有这些化合物的农药。

    ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE
    10.
    发明申请
    ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE 有权
    ISOXAZOLINE-替代苄基化合物和杀虫剂

    公开(公告)号：US20130296559A1

    公开(公告)日：2013-11-07

    申请号：US13850067

    申请日：2013-03-25

    申请人： Nissan Chemical Industries, Ltd

    发明人： Takeshi MITA ,  Takamase Kikuchi ,  Takashi Mizukoshi ,  Manabu Yaosaka ,  Mitsuaki Komoda

    IPC分类号： C07D413/14 ,  C07D413/12 ,  C07D261/04

    CPC分类号： A61K31/421 ,  A01N43/80 ,  A61K9/0053 ,  C07C25/02 ,  C07C25/06 ,  C07C25/08 ,  C07C25/13 ,  C07C25/24 ,  C07C43/1742 ,  C07C43/1745 ,  C07C205/11 ,  C07C205/12 ,  C07C211/52 ,  C07C251/48 ,  C07C255/29 ,  C07C255/50 ,  C07C255/60 ,  C07C281/02 ,  C07C323/09 ,  C07D261/04 ,  C07D261/16 ,  C07D413/04 ,  C07D413/06 ,  C07D413/12 ,  C07D413/14 ,  C07D417/06 ,  C07D417/12 ,  C07F7/0812

    摘要： A substituted alkenylbenzene compound of formula (4): wherein X1 is selected from the group consisting of a halogen atom, —SF5, C1-C6haloalkyl, hydroxy C1-C6haloalkyl, C1-C6alkoxy C1-C6haloalkyl, C3-C8halocycloalkyl, C1-C6haloalkoxy, C1-C3haloalkoxy C1-C3haloalkoxy, C1-C6haloalkylthio, C1-C6haloalkylsulfinyl and C1-C6haloalkylsulfonyl; X3 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, nitro, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy and C1-C6alkylthio; X4 is selected from the group consisting of a hydrogen atom, halogen atom, cyano, C1-C4alkyl, C1-C4alkoxy and C1-C4haloalkoxy; R3 is —C(R3a)(R3b)R3c, where R3a and R3b independently of each other are a halogen atom, or R3a and R3b together form 3- to 6-membered ring together with the carbon atom bonding them by forming a C2-C5haloalkylene chain, and R3c is selected from the group consisting of a hydrogen atom, halogen atom. C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy and C1-C4haloalkylthio, with a proviso that in case where X1 is a fluorine atom, chlorine atom or trifluoromethyl, and both X2 and X3 are a hydrogen atom, in case where both X1 and X2 are fluorine atom and X3 is a hydrogen atom, and in case where both X1 and X2 are trifluoromethyl and X3 is a hydrogen atom. R3c is a hydrogen atom, chlorine atom, bromine atom, iodine atom, C1-C5alkyl, C1-C5haloalkyl, C1-C4haloalkoxy or C1-C4haloalkylthio.

    摘要翻译： 式（4）的取代烯基苯化合物：其中X 1选自卤素原子，-SF 5，C 1 -C 6卤代烷基，羟基C 1 -C 6卤代烷基，C 1 -C 6烷氧基C 1 -C 6卤代烷基，C 3 -C 8卤代环烷基，C 1 -C 6卤代烷氧基， C 1 -C 3卤代烷氧基C 1 -C 3卤代烷氧基，C 1 -C 6卤代烷硫基，C 1 -C 6卤代烷基亚磺酰基和C 1 -C 6卤代烷基磺酰基; X 3选自氢原子，卤素原子，氰基，硝基，C 1 -C 6烷基，C 1 -C 6卤代烷基，C 1 -C 6烷氧基和C 1 -C 6烷硫基; X 4选自氢原子，卤素原子，氰基，C 1 -C 4烷基，C 1 -C 4烷氧基和C 1 -C 4卤代烷氧基; R3是-C（R3a）（R3b）R3c，其中R3a和R3b彼此独立地是卤素原子，或者R3a和R3b与通过形成C2- C5卤代亚烷基，R3c选自氢原子，卤素原子。 C1-C5烷基，C1-C5卤代烷基，C1-C4卤代烷氧基和C1-C4卤代烷硫基，条件是在X1为氟原子，氯原子或三氟甲基的情况下，X2和X3均为氢原子，在X1和 X2为氟原子，X3为氢原子，X1和X2均为三氟甲基，X3为氢原子的情况。 R3c是氢原子，氯原子，溴原子，碘原子，C1-C5烷基，C1-C5卤代烷基，C1-C4卤代烷氧基或C1-C4卤代烷硫基。