FET nanopore sensor
    9.
    发明授权
    FET nanopore sensor 有权
    FET纳米孔传感器

    公开(公告)号:US08828138B2

    公开(公告)日:2014-09-09

    申请号:US12781514

    申请日:2010-05-17

    IPC分类号: C30B1/06 G01N27/414 B82Y15/00

    摘要: A method of using a sensor comprising a field effect transistor (FET) embedded in a nanopore includes placing the sensor in an electrolyte comprising at least one of biomolecules and deoxyribonucleic acid (DNA); placing an electrode in the electrolyte; applying a gate voltage in the sub-threshold regime to the electrode; applying a drain voltage to a drain of the FET; applying a source voltage to a source of the FET; detecting a change in a drain current in the sensor in response to the at least one of biomolecules and DNA passing through the nanopore.

    摘要翻译: 使用包含嵌入在纳米孔中的场效应晶体管(FET)的传感器的方法包括将传感器放置在包含生物分子和脱氧核糖核酸(DNA)中的至少一种的电解质中; 将电极放置在电解质中; 将所述子阈值状态中的栅极电压施加到所述电极; 将漏极电压施加到FET的漏极; 将源电压施加到FET的源极; 响应于生物分子和通过纳米孔的DNA中的至少一个,检测传感器中的漏极电流的变化。