公开(公告)号：US5179094A

公开(公告)日：1993-01-12

申请号：US672763

申请日：1991-03-19

申请人： Odd Kristiansen ,  Manfred Boger ,  Haukur Kristinsson ,  Peter Maienfisch

发明人： Odd Kristiansen ,  Manfred Boger ,  Haukur Kristinsson ,  Peter Maienfisch

IPC分类号： A01N43/707 ,  C07D401/12

CPC分类号： C07D401/12 ,  A01N43/707

摘要： There are disclosed novel substituted N-amino-1,2,4-triazinones of formula I ##STR1## wherein R.sub.1 is C.sub.1 -C.sub.12 alkyl or C.sub.3 -C.sub.7 cycloalkyl,R.sub.2 and R.sub.3 are each independently of the other hydrogen or C.sub.1 -C.sub.6 alkyl,R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are each independently of one another hydrogen, halogen, C.sub.1 -C.sub.3 alkyl, ##STR2## C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio, and n is 0 or 1, or a salt thereof, with the proviso that n is 1, if simultaneously the pyridine ring is attached via the 3-position to the methylidene group and R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are each hydrogen; their use in pest control and pesticidal compositions which contain a compound of formula I as active component. The preferred utility is the control of pests of animals and plants.

摘要翻译： 公开了式I（I）的新的取代的N-氨基-1,2,4-三嗪酮，其中R 1是C 1 -C 12烷基或C 3 -C 7环烷基，R 2和R 3各自独立地是另一个氢或C 1 -C 6烷基 ，R 4，R 5，R 6和R 7各自独立地为氢，卤素，C 1 -C 3烷基，C 1 -C 3烷氧基或C 1 -C 3烷硫基，n为0或1，或其盐，条件是n 是1，如果同时吡啶环通过3-位连接到亚甲基上，并且R4，R5，R6和R7各自为氢; 它们在害虫控制中的用途和含有式I化合物作为活性成分的杀虫组合物。 优选的效用是控制动物和植物的害虫。

公开(公告)号：US5077412A

公开(公告)日：1991-12-31

申请号：US414998

申请日：1989-09-29

申请人： Josef Ehrenfreund ,  Manfred Boger ,  Odd Kristiansen ,  Jozef Drabek ,  Haukur Kristinsson

发明人： Josef Ehrenfreund ,  Manfred Boger ,  Odd Kristiansen ,  Jozef Drabek ,  Haukur Kristinsson

IPC分类号： A01N47/30 ,  A01N47/32 ,  A01N47/40 ,  A01N47/42 ,  C07D207/34 ,  C07D209/32 ,  C07D231/20 ,  C07D233/70 ,  C07D235/26 ,  C07D249/12 ,  C07D257/04 ,  C07D263/38 ,  C07D263/58 ,  C07D271/10 ,  C07D271/113 ,  C07D277/20 ,  C07D277/34 ,  C07D277/68 ,  C07D285/08 ,  C07D285/12 ,  C07D285/13 ,  C07D307/58 ,  C07D333/32 ,  C07D333/34

CPC分类号： C07D271/113 ,  A01N47/30 ,  A01N47/32 ,  A01N47/40 ,  A01N47/42 ,  C07D233/70 ,  C07D249/12 ,  C07D277/34 ,  C07D277/68 ,  C07D285/08 ,  C07D285/13

摘要： The invention relates to novel substituted phenylthioureas, phenylisothioureas and phenylcarbodiimides of formula I ##STR1## wherein Z is ##STR2## or --N.dbd.C.dbd.N--; R.sub.1 is C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.10 alkenyl, C.sub.3 -C.sub.10 alkynyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.1 -C.sub.3 alkyl substituted by 1 or 2 C.sub.3 -C.sub.6 cycloalkyl radicals, or is alkoxyalkyl containing a total of 3 to 10 carbon atoms, halogen-substituted C.sub.1 -C.sub.12 alkyl, polycyclic C.sub.7 -C.sub.10 cycloalkyl, or phenyl(C.sub.1 -C.sub.5)alkyl which may be substituted in the phenyl moiety by 1 or 2 identical or different members selected from the group consisting of halogen, methoxy, ethoxy and C.sub.1 -C.sub.5 alkyl,R.sub.2 is hydrogen or C.sub.1 -C.sub.5 alkyl,R.sub.3 is C.sub.1 -C.sub.5 alkyl or C.sub.3 -C.sub.6 cycloalkyl,R.sub.4 is hydrogen or C.sub.1 -C.sub.4 alkyl,R.sub.5 is a 5-membered heterocyclic radical containing 1 to 4 hetero atoms selected from the group consisting of N, O and S, which radical may be substituted at the carbon or nitrogen atoms by 1 to 3 of the substituents R.sub.6, R.sub.7 and R.sub.8, or is a 5-membered heterocyclic radical which may be fused with benzene nuclei and which contains 1 or 2 hetero atoms selected from the group consisting of N, O and S and can be substituted at the carbon or nitrogen atoms by 1 to 3 of the substituents R.sub.6, R.sub.7 and R.sub.8,R.sub.6 and R.sub.7 are each independently of the other hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, halogen-substituted C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy; halogen-substituted C.sub.1 -C.sub.4 alkoxy, phenyl, or C.sub.1 -C.sub.4 alkylthio,R.sub.8 is hydrogen or C.sub.1 -C.sub.4 alkyl, andR.sub.9 is C.sub.1 -C.sub.5 alkyl, C.sub.2 -C.sub.5 alkenyl, C.sub.3 -C.sub.4 alkynyl, alkoxyalkyl containing a total of 10 carbon atoms, or alkylthioalkyl containing a total of 10 carbon atomsand to the salts thereof with acids and bases. The invention further relates to the preparation of these compounds and to the use thereof in pest control, and to novel intermediates.

公开(公告)号：US4888348A

公开(公告)日：1989-12-19

申请号：US91157

申请日：1987-08-28

申请人： Josef Ehrenfreund ,  Manfred Boger ,  Odd Kristiansen ,  Jozef Drabek ,  Haukur Kristinsson

发明人： Josef Ehrenfreund ,  Manfred Boger ,  Odd Kristiansen ,  Jozef Drabek ,  Haukur Kristinsson

IPC分类号： A01N47/30 ,  A01N47/32 ,  A01N47/40 ,  A01N47/42 ,  C07D207/34 ,  C07D209/32 ,  C07D231/20 ,  C07D233/70 ,  C07D235/26 ,  C07D249/12 ,  C07D257/04 ,  C07D263/38 ,  C07D263/58 ,  C07D271/10 ,  C07D271/113 ,  C07D277/20 ,  C07D277/34 ,  C07D277/68 ,  C07D285/08 ,  C07D285/12 ,  C07D285/13 ,  C07D307/58 ,  C07D333/32 ,  C07D333/34

CPC分类号： C07D271/113 ,  A01N47/30 ,  A01N47/32 ,  A01N47/40 ,  A01N47/42 ,  C07D233/70 ,  C07D249/12 ,  C07D277/34 ,  C07D277/68 ,  C07D285/08 ,  C07D285/13

摘要： The invention relates to novel substituted phenylthioureas, phenylisothioureas and phenylcarbodiimides of formula I ##STR1## wherein Z is ##STR2## or --N.dbd.C.dbd.N--; R.sub.1 is C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.10 alkenyl, C.sub.3 -C.sub.10 alkynyl, C.sub.3 -C.sub.8 cycloalkyl, C.sub.1 -C.sub.3 alkyl substituted by 1 or 2 C.sub.3 -C.sub.6 cycloalkyl radicals, or is alkoxyalkyl containing a total of 3 to 10 carbon atoms, halogen-substituted C.sub.1 -C.sub.12 alkyl, polycyclic C.sub.7 -C.sub.10 cycloalkyl, or phenyl(C.sub.1 -C.sub.5)alkyl which may be substituted in the phenyl moiety by 1 or 2 identical or different members selected from the group consisting of halogen, methoxy, ethoxy and C.sub.1 -C.sub.5 alkyl,R.sub.2 is hydrogen or C.sub.1 -C.sub.5 alkyl,R.sub.3 is C.sub.1 -C.sub.5 alkyl or C.sub.3 -C.sub.6 cycloalkyl,R.sub.4 is hydrogen or C.sub.1 -C.sub.4 alkyl,R.sub.5 is a 5-membered heterocyclic radical containing 1 to 4 hetero atoms selected from the group consisting of N, O and S, which radical may be substituted at the carbon or nitrogen atoms by 1 to 3 of the substituents R.sub.6, R.sub.7 and R.sub.8, or is a 5-membered heterocyclic radical which may be fused with benzene nuclei and which contains 1 or 2 hetero atoms selected from the group consisting of N, O and S and can be substituted at the carbon or nitrogen atoms by 1 to 3 of the substituents R.sub.6, R.sub.7 and R.sub.8,R.sub.6 and R.sub.7 are each independently of the other hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, halogen-substituted C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy; halogen-substituted C.sub.1 -C.sub.4 alkoxy, phenyl, or C.sub.1 -C.sub.4 alkylthio,R.sub.8 is hydrogen or C.sub.1 -C.sub.4 alkyl, andR.sub.9 is C.sub.1 -C.sub.5 alkyl, C.sub.2 -C.sub.5 alkenyl, C.sub.3 -C.sub.4 alkynyl, alkoxyalkyl containing a total of 10 carbon atoms, or alkylthioalkyl containing a total of 10 carbon atomsand to the salts thereof with acids and bases. The invention further relates to the preparation of these compounds and to the use thereof in pest control, and to novel intermediates.

摘要翻译： 本发明涉及式I的新的取代的苯基硫脲，苯基异硫脲和苯基碳二亚胺其中Z是或-N = C = N-; R 1是C 1 -C 12烷基，C 3 -C 10烯基，C 3 -C 10炔基，C 3 -C 8环烷基，被1或2个C 3 -C 6环烷基取代的C 1 -C 3烷基，或者是含有总共3至10个碳原子的烷氧基烷基，卤素取代的C 1 -C 12烷基 ，多环C 7 -C 10环烷基或可在苯基部分被1或2个选自卤素，甲氧基，乙氧基和C 1 -C 5烷基的相同或不同的成员取代的苯基（C 1 -C 5）烷基，R 2为氢或 C 1 -C 5烷基，R 3是C 1 -C 5烷基或C 3 -C 6环烷基，R 4是氢或C 1 -C 4烷基，R 5是含有1至4个选自N，O和S的杂原子的5元杂环基， 可以在碳原子或氮原子上被1至3个取代基R6，R7和R8取代，或者是可以与苯核稠合并且含有1或2个选自以下的杂原子的5元杂环基： 的N，O和S，并且可以在碳或氮原子上被1至3个取代 取代基R 6，R 7和R 8，R 6和R 7各自独立地为氢，卤素，C 1 -C 4烷基，卤素取代的C 1 -C 4烷基，C 1 -C 4烷氧基， 卤素取代的C1-C4烷氧基，苯基或C1-C4烷硫基，R8是氢或C1-C4烷基，R9是C1-C5烷基，C2-C5链烯基，C3-C4炔基，含有总共10个碳原子的烷氧基烷基，或含有 总共10个碳原子，并与其与酸和碱的盐反应。 本发明进一步涉及这些化合物的制备及其在病虫害防治中的应用，以及新颖的中间体。

公开(公告)号：US4783468A

公开(公告)日：1988-11-08

申请号：US41163

申请日：1987-04-22

申请人： Haukur Kristinsson ,  Odd Kristiansen

发明人： Haukur Kristinsson ,  Odd Kristiansen

IPC分类号： C07F9/24 ,  A01N33/04 ,  A01N33/08 ,  A01N33/10 ,  A01N39/00 ,  A01N43/54 ,  A01N45/02 ,  A01N47/18 ,  A01N47/36 ,  A01N49/00 ,  A01N57/08 ,  A01N57/32 ,  A01P3/00 ,  A01P7/04 ,  C07C67/00 ,  C07C209/00 ,  C07C211/35 ,  C07C211/40 ,  C07C213/00 ,  C07C215/02 ,  C07C215/20 ,  C07C215/26 ,  C07C215/42 ,  C07C217/00 ,  C07C217/52 ,  C07C313/00 ,  C07C323/26 ,  C07C323/28 ,  C07C323/36 ,  C07D239/47 ,  C07D239/48 ,  C07D239/50 ,  C07D239/69 ,  C07D401/04 ,  C07D403/04 ,  C07F9/547 ,  C07F9/6512

CPC分类号： A01N49/00 ,  A01N33/04 ,  A01N33/08 ,  A01N33/10 ,  A01N39/00 ,  A01N43/54 ,  A01N45/02 ,  A01N57/32 ,  C07D239/48 ,  C07D239/50 ,  C07F9/65127 ,  Y10T428/31649 ,  Y10T428/31652 ,  Y10T428/31678

摘要： The invention relates to novel substituted 2,4-diamino-5-cyano-pyrimidines of formula ##STR1## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.2 -C.sub.6 alkenyl or C.sub.2 -C.sub.6 alkynyl,R.sub.2 is hydrogen, C.sub.1 -C.sub.10 alkyl or C.sub.3 -C.sub.6 cycloalkyl, orR.sub.1 and R.sub.2, when taken together, are a radical selected from the group consisting of--(CH.sub.2).sub.3 --,--(CH.sub.2).sub.4 and--(CH.sub.2).sub.5,R.sub.5 is hydrogen or a radical--CO--R.sub.5 or--SO.sub.2 --R.sub.6,R.sub.4 is a radical selected from the group consisting of --NH.sub.2,--NH--CO--R.sub.5,--NH--SO.sub.2 --R.sub.6, ##STR2## or --NH--CH.dbd.N--R.sub.10 ; R.sub.5 is hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.6 alkoxy, perhalogenated C.sub.1 -C.sub.3 alkyl or the radical ##STR3## R.sub.6 is C.sub.1 -C.sub.6 alkyl, R.sub.7 is hydrogen or C.sub.1 -C.sub.6 alkyl,R.sub.8 and R.sub.9 are each independently of the other hydrogen or C.sub.1 -C.sub.6 alkyl or, when taken together, are a radical selected from the group consisting of--(CH.sub.2).sub.3 --,--(CH.sub.2).sub.4 --and--(CH.sub.2).sub.5,R.sub.10 is a radical--SO.sub.2 --R.sub.13 or ##STR4## R.sub.11 and R.sub.12 are each independently of the other hydrogen or C.sub.1 -C.sub.6 -alkyl or, when taken together, are a radical selected from the group consisting of--(CH.sub.2).sub.3 --,--(CH.sub.2).sub.4 --and--(CH.sub.2).sub.5,R.sub.13 is C.sub.1 -C.sub.10 alkyl, C.sub.1 -C.sub.10 alkyl which is substituted by up to 10 halogen atoms, or is C.sub.3 -C.sub.6 cycloalkylR.sub.14 and R.sub.15 are each independently of the other C.sub.1 -C.sub.10 alkyl; andX and Y are each independently of the other oxygen or sulfur, and salts thereof, to the preparation and intermediates for the preparation thereof, and to compositions containing these compounds for controlling insects and representatives of the order Acarina, in particular plant-destructive feeding insects and ectoparasites that attack animals.

摘要翻译： 本发明涉及式（I）的新的取代的2,4-二氨基-5-氰基嘧啶，其中R 1是氢，C 1 -C 6烷基，C 2 -C 6烯基或C 2 -C 6炔基，R 2是氢，C 1 -C 10烷基或 C 1 -C 6环烷基或R 1和R 2一起为选自 - （CH 2）3 - ， - （CH 2）4和 - （CH 2）5的基团，R 5为氢或基团-CO- R5或-SO2-R6，R4是选自-NH2，-NH-CO-R5，-NH-SO2-R6，IMA或-NH-CH = N-R10的基团; R 5是氢，C 1 -C 12烷基，C 3 -C 6环烷基，C 1 -C 6烷氧基，全卤代C 1 -C 3烷基或基团R 6是C 1 -C 6烷基，R 7是氢或C 1 -C 6烷基，R 8和R 9各自独立地是氢 或者C 1 -C 6烷基，或者当它们一起是选自 - （CH 2）3 - ， - （CH 2）4 - 和 - （CH 2）5的基团时，R 10是基团-SO 2 -R 13或

公开(公告)号：US5783704A

公开(公告)日：1998-07-21

申请号：US669452

申请日：1996-06-28

申请人： Henry Szczepanski ,  Haukur Kristinsson ,  Peter Maienfisch ,  Josef Ehrenfreund

发明人： Henry Szczepanski ,  Haukur Kristinsson ,  Peter Maienfisch ,  Josef Ehrenfreund

IPC分类号： A01C20060101 ,  A01N20060101 ,  A01N43/40 ,  A01N43/50 ,  A01N43/54 ,  A01N43/653 ,  A01N43/707 ,  A01N43/76 ,  A01N43/78 ,  A01N43/824 ,  A01N43/88 ,  C07D20060101 ,  C07D253/06 ,  C07D285/12 ,  C07D285/13 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12

CPC分类号： C07D253/06 ,  A01N43/40 ,  A01N43/50 ,  A01N43/653 ,  C07D285/13 ,  C07D401/12

摘要： Compounds of formu (I) wherein n and Z are as defined in claim 1, and, where appropriate, tautomers thereof, in each case in free form, or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner known per se.

摘要翻译： PCT No.PCT / EP94 / 04222 Sec。 371日期：1996年6月28日 102（e）日期1996年6月28日PCT 1994年12月19日PCT公布。 WO95 / 18123 PCT出版物 日期1995年7月6日，其中n和Z如权利要求1中所定义的formu（I）化合物，并且在适当的情况下，其互变异构体以游离形式或盐形式，可用作农业化学活性成分， 可以以本身已知的方式制备。

公开(公告)号：US4379147A

公开(公告)日：1983-04-05

申请号：US344280

申请日：1982-02-01

申请人： Manfred Boger ,  Urs Burckhardt ,  Haukur Kristinsson ,  Gunter Mattern ,  Walter Traber

发明人： Manfred Boger ,  Urs Burckhardt ,  Haukur Kristinsson ,  Gunter Mattern ,  Walter Traber

IPC分类号： A01N43/50 ,  A01N57/32 ,  C07D233/24 ,  C07D401/12 ,  C07F9/6506 ,  C07F9/24

CPC分类号： C07F9/65061 ,  A01N43/50 ,  A01N57/32 ,  C07D233/24

摘要： Compounds of the formula ##STR1## wherein R.sub.1 and R.sub.2 independently of one another are each a chlorine atom or the methyl group, Y is the group ##STR2## or --CH.dbd.N--R.sub.5, in which R.sub.3 is methyl or ethyl, R.sub.4 is alkyl having 1 to 4 carbon atoms, alkoxy having 1 or 2 carbon atoms, alkylthio having 1 to 4 carbon atoms, or phenyl, X is an oxygen atom or a sulfur atom, and R.sub.5 is an unsubstituted or substituted pyridinyl group which is linked by way of one of its carbon atoms, to the main part of the molecule, and which has substituents selected from the group comprising halogen and alkyl having 1 to 4 carbon atoms, including the acid addition salts thereof, processes for producing the novel compounds by reaction of 2-(anilinomethyl)-2-imidazoline derivatives either with (thio)phosphoric acid dialkyl ester halides or alkyl(thio) phosphonic acid alkyl ester halides, or with N-pyridinylformiminoalkoxy derivatives. The resulting compounds and compositions containing them are effective against members of the order Acarina, and against animal and plant lice, as well as against members of the Calliphoridae family.

摘要翻译： 其中R 1和R 2彼此独立地为氯原子或甲基的式“IMAGE”的化合物，Y为基团，或其中R 3为甲基或乙基，R 4为 具有1至4个碳原子的烷基，具有1或2个碳原子的烷氧基，具有1至4个碳原子的烷硫基，或苯基，X是氧原子或硫原子，R 5是未取代或取代的吡啶基，其通过 其一个碳原子的方式，分子的主要部分，并且其具有选自卤素和具有1至4个碳原子的烷基的取代基，包括其酸加成盐，通过反应生产新化合物的方法 （硫代）磷酸二烷基酯卤化物或烷基（硫代）膦酸烷基酯卤化物，或N-吡啶基亚甲酰基烷氧基衍生物的2-（苯胺基甲基）-2-咪唑啉衍生物。 所得到的含有它们的化合物和组合物对于Acarina，对动物和植物虱以及对Calliphoridae家族的成员是有效的。

公开(公告)号：US6034083A

公开(公告)日：2000-03-07

申请号：US119285

申请日：1998-07-20

申请人： Henry Szczepanski ,  Haukur Kristinsson ,  Peter Maienfisch ,  Josef Ehrenfreund

发明人： Henry Szczepanski ,  Haukur Kristinsson ,  Peter Maienfisch ,  Josef Ehrenfreund

IPC分类号： A01C20060101 ,  A01N20060101 ,  A01N43/40 ,  A01N43/50 ,  A01N43/54 ,  A01N43/653 ,  A01N43/707 ,  A01N43/76 ,  A01N43/78 ,  A01N43/824 ,  A01N43/88 ,  C07D20060101 ,  C07D253/06 ,  C07D285/12 ,  C07D285/13 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  A61K31/53

CPC分类号： C07D253/06 ,  A01N43/40 ,  A01N43/50 ,  A01N43/653 ,  C07D285/13 ,  C07D401/12

摘要： Compounds of formula ##STR1## wherein n and Z are as defined in claim 1, and, where appropriate, tautomers thereof, in each case in free form or in salt form, can be used as agrochemical active ingredients and can be prepared in a manner known per se.

摘要翻译： 其中n和Z如权利要求1所定义的化合物，并且在适当的情况下，其互变异构体在每种情况下以游离形式或盐形式可用作农业化学活性成分，并且可以以本身已知的方式制备 。

公开(公告)号：US4629802A

公开(公告)日：1986-12-16

申请号：US707358

申请日：1985-03-01

申请人： Haukur Kristinsson ,  Werner Topfl

发明人： Haukur Kristinsson ,  Werner Topfl

IPC分类号： C07D251/46 ,  A01N47/36 ,  A01N47/42 ,  C07C67/00 ,  C07C301/00 ,  C07C303/38 ,  C07C303/40 ,  C07C311/63 ,  C07D239/42 ,  C07D239/47 ,  C07D251/16 ,  C07D521/00 ,  C07C119/20

CPC分类号： C07D521/00

摘要： A novel process for producing sulfonylureas of the formula I having a herbicidal action and an action regulating plant growth ##STR1## wherein A is an unsubstituted or substituted phenyl, naphthyl, furan, thiophene or pyridine group, E is a nitrogen atom or the methine group, R.sub.a is hydrogen, halogen, C.sub.1 -C.sub.5 -alkyl, C.sub.1 -C.sub.5 -haloalkyl, C.sub.1 -C.sub.5 -alkoxy, C.sub.1 -C.sub.5 -haloalkoxy, C.sub.1 -C.sub.5 -alkylthio or C.sub.2 -C.sub.10 -alkoxyalkoxy, and R.sub.b is the same as R.sub.a or is an unsubstituted or substituted amino group, and salts thereof, which process comprises firstly condensing an imidocarbonic acid ester with a sulfonyl chloride of the formula II to the sulfonylimidocarbonic acid diester of the formula IV ##STR2## wherein R is an alkyl group, and reacting this in an ethereal solvent in the presence of sodium hydride or potassium tertbutylate with a 2-aminopyrimidine or 2-amino-1,3,5-triazine of the formula V, and finally reacting the formed sulfonylisourea of the formula VI in an organic solvent with hydrochloric acid to obtain the sulfonylurea of the formula I, and isolating this as such or as a salt; ##STR3## The sulfonylimidocarbonic acid diesters of the formula IV and certain sulfonylisoureas of the formula VI, required as intermediates, are novel compounds. The process has the advantage that no sulfonamides are needed as intermediates.

摘要翻译： 一种制备具有除草作用和调节植物生长作用的式I的磺酰脲的新方法，其中A是未取代或取代的苯基，萘基，呋喃，噻吩或吡啶基，E是氮原子或 次甲基，R a为氢，卤素，C 1 -C 5 - 烷基，C 1 -C 5 - 卤代烷基，C 1 -C 5 - 烷氧基，C 1 -C 5 - 卤代烷氧基，C 1 -C 5 - 烷硫基或C 2 -C 10 - 烷氧基烷氧基，Rb为 与R a相同或为未取代或取代的氨基及其盐，该方法包括首先将亚氨基碳酸酯与式II的磺酰氯缩合成式IV的磺酰亚胺基碳酸二酯其中R是烷基 并将其在惰性溶剂中，在氢化钠或叔丁醇钾存在下与式V的2-氨基嘧啶或2-氨基-1,3,5-三嗪反应，最后使形成的式VI的磺酰基异脲 在有盐酸的有机溶剂中 在式I的磺酰脲中，并将其分离为盐或盐; 作为中间体，式IV的磺酰亚胺基碳酸二酯和式VI的某些磺酰基异脲是新化合物。 该方法的优点是不需要磺酰胺作为中间体。

公开(公告)号：US5561230A

公开(公告)日：1996-10-01

申请号：US460342

申请日：1995-06-02

申请人： Ernst Beriger ,  Haukur Kristinsson

发明人： Ernst Beriger ,  Haukur Kristinsson

IPC分类号： C07D253/06 ,  C07D271/10 ,  C07D271/113 ,  C07D401/12 ,  C07D413/06

CPC分类号： C07D253/06 ,  C07D271/113 ,  C07D401/12 ,  C07D413/06

摘要： The invention relates to a process for the preparation of a compound of formula ##STR1## useful as intermediate for the preparation of pesticides, wherein R is hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkyl substituted by from 1 to 10 halogen atoms or by from 1 to 3 radicals selected from the group consisting of C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio and phenyl, phenyl or phenyl substituted by from 1 to 3 radicals selected from the group consisting of halogen, methyl, ethyl, methoxy, methylthio and nitro, which comprises reacting with hydrazine hydrate a compound of formula ##STR2## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, C.sub.1 -C.sub.4 alkyl substituted by from 1 to 9 chlorine atoms, C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio, C.sub.1 -C.sub.3 alkylsulfinyl, C.sub.1 -C.sub.3 alkylsulfonyl, phenyl, phenyl substituted by from 1 to 3 radicals selected from the group consisting of halogen, methyl, ethyl, methoxy, methylthio and nitro, or pyridyl, and subjecting to hydrolysis the resulting compound of formula ##STR3##

摘要翻译： 本发明涉及制备式（I）化合物的方法，其可用作制备农药的中间体，其中R是氢，C 1 -C 6烷基，C 3 -C 6环烷基，被1至 10个卤素原子或1至3个选自C 1 -C 3烷氧基，C 1 -C 3烷硫基和苯基的基团，苯基或被1至3个选自卤素，甲基，乙基，甲氧基， 甲硫基和硝基，其包括与水合肼反应其中R 1是氢，C 1 -C 4烷基，C 3 -C 6环烷基，被1至9个氯原子取代的C 1 -C 4烷基，C 1 -C 3烷氧基，C 1 C 3烷硫基，C 1 -C 3烷基亚磺酰基，C 1 -C 3烷基磺酰基，苯基，被1至3个选自卤素，甲基，乙基，甲氧基，甲硫基和硝基或吡啶基的基取代的苯基，并将所得化合物 公式（III）

公开(公告)号：US4388464A

公开(公告)日：1983-06-14

申请号：US232752

申请日：1981-02-09

申请人： Haukur Kristinsson ,  Beat Muller ,  Johannes P. Pachlatko

发明人： Haukur Kristinsson ,  Beat Muller ,  Johannes P. Pachlatko

IPC分类号： A01N25/32 ,  A01N43/824 ,  C07C251/32 ,  C07C259/10 ,  C07C311/16 ,  C07C317/32 ,  C07C317/44 ,  C07C317/46 ,  C07C317/48 ,  C07C323/47 ,  C07C327/20 ,  C07D213/53 ,  C07D213/61 ,  C07D213/64 ,  C07D213/65 ,  C07D213/69 ,  C07D213/70 ,  C07D213/79 ,  C07D215/32 ,  C07D215/34 ,  C07D233/26 ,  C07D233/86 ,  C07D235/14 ,  C07D235/16 ,  C07D249/06 ,  C07D263/56 ,  C07D263/58 ,  C07D277/64 ,  C07D285/12 ,  C07D285/125 ,  C07D285/13 ,  C07D307/20 ,  C07D307/52 ,  C07D309/20 ,  C07D309/32 ,  C07D311/58 ,  C07D317/58 ,  C07D335/06 ,  C07D339/06 ,  C07D339/08 ,  A01N43/82 ,  A01N47/40

CPC分类号： C07D213/53 ,  C07D213/61 ,  C07D213/64 ,  C07D213/65 ,  C07D213/69 ,  C07D213/70 ,  C07D213/79 ,  C07D215/32 ,  C07D215/34 ,  C07D233/26 ,  C07D233/86 ,  C07D235/14 ,  C07D235/16 ,  C07D249/06 ,  C07D263/56 ,  C07D277/64 ,  C07D285/12 ,  C07D285/125 ,  C07D285/13 ,  C07D307/20 ,  C07D307/52 ,  C07D309/20 ,  C07D309/32 ,  C07D311/58 ,  C07D317/58 ,  C07D335/06 ,  C07D339/06 ,  C07D339/08 ,  Y10S47/03

摘要： A process for protecting cultivated plants against aggressive agricultural chemicals is described in which oxime derivatives of the formula ##STR1## are used as antidotes. Either the cultivated area for the cultivated plants or the cultivated plants themselves or parts of the plant (seeds, tubers, stem parts and the like), as desired, can be treated with these oxime derivatives, which are used as a dressing.Ar is a phenyl radical of the formula ##STR2## or Ar is also a 5-membered to 10-membered heterocyclic radical which contains not more than three identical or different hetero-atoms N, O and/or S and which can be bonded via a C.sub.1 - to C.sub.3 -aliphatic chain to the remainder of the molecule and which is substituted by R.sub.1, R.sub.2 or R.sub.3 and can be substituted by oxo or thiono; X is hydrogen, CN, halogen, C.sub.1 -C.sub.10 -alkyl, lower alkanoyl, --COOH, a carboxylic acid ester of a carboxamide radical; and Q is hydrogen, lower alkyl, which can be interrupted by hetero-atoms or substituted by halogen or cyano, lower alkenyl or halogenoalkenyl, lower alkynyl, C.sub.3 -C.sub.7 cycloalkyl, which is unsubstituted or substituted by halogen, or a lower alkanecarboxylic acid ester group, a lower alkanecarboxylic acid thioester group, a lower alkanecarboxamide group, an aliphatic acyl radical, an araliphatic, cycloaliphatic or substituted or unsubstituted aromatic or heterocyclic acyl radical, an alkylsulfonyl radical, a sulfonamide radical, a metal salt, a quaternized ammonium salt or an aliphatic, araliphatic, cycloaliphatic or substituted or unsubstituted aromatic or heterocyclic carbonic acid, thiocarbonic acid or carbamoyl radical.

摘要翻译： 描述了用于保护栽培植物免受侵袭性农药的方法，其中使用式“IMAGE”的肟衍生物作为解毒剂。 根据需要，可以用这些用作敷料的肟衍生物来处理栽培植物或栽培植物本身或植物的部分（种子，块茎，茎部等）的栽培面积。 Ar是下式的苯基或Ar也是5元至10元杂环基，其含有不超过三个相同或不同的杂原子N，O和/或S，并且可以通过 与分子的其余部分存在的C 1 -C 3 - 脂族链，并被R 1，R 2或R 3取代并且可被氧代或硫代替代; X是氢，CN，卤素，C 1 -C 10 - 烷基，低级烷酰基，-COOH，羧酰胺基的羧酸酯; Q为氢原子，可被杂原子或被卤素或氰基取代的低级烷基，低级链烯基或卤代烯基，低级炔基，未被取代或被卤素取代的C3-C7环烷基或低级链烷羧酸酯 低级链烷羧酸硫酯基，低级链烷酰胺基，脂族酰基，芳脂族，脂环族或取代或未取代的芳族或杂环酰基，烷基磺酰基，磺酰胺基，金属盐，季铵化铵盐或 脂族，芳脂族，脂环族或取代或未取代的芳族或杂环碳酸，硫代碳酸或氨基甲酰基。