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1.发明授权Method of attaching hydrophilic species to hydrophilic macromolecules and immobilizing the hydrophilic macromolecules on a hydrophobic surface 失效将亲水性物质附着到亲水性大分子上并将亲水性大分子固定在疏水性表面上的方法公开(公告)号：US07785901B2
公开(公告)日：2010-08-31
申请号：US10631351
申请日：2003-07-31
申请人： Oliver Harnack , William E. Ford , Jurina Wessels , Akio Yasuda
发明人： Oliver Harnack , William E. Ford , Jurina Wessels , Akio Yasuda
IPC分类号： G01N33/553
CPC分类号： G01N33/54393
摘要： The present invention is related to a method of attaching hydrophilic species to hydrophilic macromolecules and immobilizing the hydrophilic macromolecules on a hydrophobic surface, to a nano-assembly and to uses of the nano-assembly.
摘要翻译： 本发明涉及将亲水性物质附着到亲水性大分子上并将亲水性大分子固定在疏水性表面上的方法，纳米组合物的使用和纳米组合物的使用。
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2.发明授权公开(公告)号：US06888150B2
公开(公告)日：2005-05-03
申请号：US10316722
申请日：2002-12-11
申请人： Oliver Harnack , Jurina Wessels , William E. Ford , Akio Yasuda
发明人： Oliver Harnack , Jurina Wessels , William E. Ford , Akio Yasuda
IPC分类号： G01N23/225 , B82B3/00 , G01Q60/40 , H01B13/00 , H01J37/26 , H01J37/28 , H01J37/30 , H01J37/305
摘要： The invention relates to a method for defect and conductivity engineering of an individual part in a conducting nanoscaled structure by generating heat-induced migration, melting, sputtering and/or evaporation of conductive material of the nanoscaled structure by directing a focussed electron beam on this individual part of the structure to be engineered. The invention further relates to the use of a secondary electron microscope having a filter for detecting back scattered electrons for such a method and a respective secondary electron microscope having such a filter for detecting back scattered electrons.
摘要翻译： 本发明涉及通过将聚焦的电子束引导到该个体上来产生导热纳米尺度结构中的各个部分的缺陷和导电性工程的方法，该方法通过产生热诱导的纳米尺度结构的导电材料的迁移，熔化，溅射和/或蒸发 部分结构要设计。 本发明还涉及具有用于检测这种方法的背散射电子的滤波器的二次电子显微镜的使用和具有用于检测反向散射电子的这种滤波器的二次电子显微镜。
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3.发明授权公开(公告)号：US06884587B2
公开(公告)日：2005-04-26
申请号：US10210812
申请日：2002-08-01
申请人： William E. Ford , Jurina Wessels , Oliver Harnack , Akio Yasuda
发明人： William E. Ford , Jurina Wessels , Oliver Harnack , Akio Yasuda
IPC分类号： B82B3/00 , C23C18/54 , H01B1/12 , H01L29/06 , H01L51/00 , H01L51/30 , C12Q1/68 , A01N43/04 , A61K31/70 , C07H21/02 , C07H21/04
CPC分类号： B82Y10/00 , H01B1/12 , H01L51/0093 , H01L51/0595 , Y10S977/895
摘要： The invention relates to a process for the metallization of nucleic acids, comprising providing tris(hydroxymethyl)phosphine-Au (THP-Au) particles or derivatives thereof, binding said THP-Au particles to a nucleic acid to produce a metal nanoparticle-nucleic acid composite, and treatment of the metal nanoparticle-nucleic acid composite with an electroless plating solution. The invention further relates to a metallized nucleic acid obtainable according to such a method and a nanowire including a method for the manufacture of a nanowire.
摘要翻译： 本发明涉及一种用于金属化核酸的方法，包括提供三（羟甲基）膦 - 金（THP-Au）颗粒或其衍生物，将所述THP-Au颗粒与核酸结合以产生金属纳米颗粒 - 核酸 复合和处理金属纳米粒子 - 核酸复合材料与化学镀溶液。 本发明还涉及根据这种方法获得的金属化核酸和包括纳米线制造方法的纳米线。
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公开(公告)号：US08137569B2
公开(公告)日：2012-03-20
申请号：US12409007
申请日：2009-03-23
申请人： Oliver Harnack , Jurina Wessels , Akio Yasuda , James Clarke , Terry Reid
发明人： Oliver Harnack , Jurina Wessels , Akio Yasuda , James Clarke , Terry Reid
CPC分类号： B01D69/10 , B01D69/105 , B01D69/144 , B81B2201/058 , B81B2203/0127 , B81C1/00087 , B81C2201/112 , Y10T428/24322 , Y10T428/24331 , Y10T428/24967 , Y10T428/24975 , Y10T428/249961
摘要： A method of fabricating a membrane having a tapered pore, a polymeric membrane having a tapered pore, and uses of such polymeric membrane are disclosed. The membrane includes apertures of increasing diameter which are aligned with each other to form the tapered pore.
摘要翻译： 公开了制造具有锥形孔的膜的方法，具有锥形孔的聚合物膜和这种聚合物膜的用途。 膜包括直径增加的孔，其彼此对准以形成锥形孔。
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公开(公告)号：US20120114925A1
公开(公告)日：2012-05-10
申请号：US13342750
申请日：2012-01-03
申请人： Oliver HARNACK , Jurina Wessels , Akio Yasuda , James Clarke , Terry Reid
发明人： Oliver HARNACK , Jurina Wessels , Akio Yasuda , James Clarke , Terry Reid
IPC分类号： B32B7/02 , B05D5/00 , C23C16/44 , B29C41/42 , B05D3/06 , B05D3/10 , B29C41/00 , B32B5/14 , C23C16/56
CPC分类号： B01D69/10 , B01D69/105 , B01D69/144 , B81B2201/058 , B81B2203/0127 , B81C1/00087 , B81C2201/112 , Y10T428/24322 , Y10T428/24331 , Y10T428/24967 , Y10T428/24975 , Y10T428/249961
摘要： A method of fabricating a membrane having a tampered pore, a polymeric membrane having a tapered pore, and uses of such polymeric membrane are disclosed. The membrane includes apertures of increasing diameter which are aligned with each other to form the tapered pore.
摘要翻译： 公开了一种制造具有篡改孔的膜的方法，具有锥形孔的聚合物膜和这种聚合物膜的用途。 膜包括直径增加的孔，其彼此对准以形成锥形孔。
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公开(公告)号：US08663780B2
公开(公告)日：2014-03-04
申请号：US13342750
申请日：2012-01-03
申请人： Oliver Harnack , Jurina Wessels , Akio Yasuda , James Clarke , Terry Reid
发明人： Oliver Harnack , Jurina Wessels , Akio Yasuda , James Clarke , Terry Reid
IPC分类号： B32B3/24
CPC分类号： B01D69/10 , B01D69/105 , B01D69/144 , B81B2201/058 , B81B2203/0127 , B81C1/00087 , B81C2201/112 , Y10T428/24322 , Y10T428/24331 , Y10T428/24967 , Y10T428/24975 , Y10T428/249961
摘要： A method of fabricating a membrane having a tampered pore, a polymeric membrane having a tapered pore, and uses of such polymeric membrane are disclosed. The membrane includes apertures of increasing diameter which are aligned with each other to form the tapered pore.
摘要翻译： 公开了一种制造具有篡改孔的膜的方法，具有锥形孔的聚合物膜和这种聚合物膜的用途。 膜包括直径增加的孔，其彼此对准以形成锥形孔。
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7.发明授权Production of platinum particle nucleic acid composite comprising subnanometer size particles 失效铂颗粒核酸复合物的生产包括亚纳米尺度颗粒公开(公告)号：US08227582B2
公开(公告)日：2012-07-24
申请号：US09990049
申请日：2001-11-21
申请人： William Ford , Jurina Wessels , Oliver Harnack , Akio Yasuda
发明人： William Ford , Jurina Wessels , Oliver Harnack , Akio Yasuda
CPC分类号： H01B1/12
摘要： The present invention provides an improved process for the direct and selective metallization of nucleic acids via metal nanoparticles produced in-situ in which a nucleic acid specific metal complex is reacted with a nucleic acid to produce a metal complex-nucleic acid conjugate, non-conjugated metal complex and/or non-conjugated by-products are removed, and the metal complex-nucleic acid conjugate is reacted with a reducing agent to produce a metal nanoparticle-nucleic acid composite. The metal nanoparticle-nucleic acid composites may be used, e. g., in the formation of nanowires, for electronic networks and circuits allowing a high density arrangement.
摘要翻译： 本发明提供了通过原位生产的金属纳米颗粒直接和选择性地金属化核酸的改进方法，其中核酸特异性金属络合物与核酸反应以产生金属络合物 - 核酸缀合物，非共轭 去除金属络合物和/或非共轭副产物，并且使金属络合物 - 核酸缀合物与还原剂反应以产生金属纳米颗粒 - 核酸复合物。 可以使用金属纳米颗粒 - 核酸复合物，例如， 例如，在形成纳米线时，用于允许高密度布置的电子网络和电路。
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公开(公告)号：US06811980B2
公开(公告)日：2004-11-02
申请号：US09988978
申请日：2001-11-19
申请人： William E. Ford , Jurina Wessels , Oliver Harnack
发明人： William E. Ford , Jurina Wessels , Oliver Harnack
IPC分类号： C12Q168
CPC分类号： C12Q1/6834 , B01J19/0046 , B01J2219/00608 , B01J2219/00612 , B01J2219/00635 , B01J2219/00722 , B01J2219/00729 , C07H21/00 , G01N33/54353 , Y10S977/924 , Y10T428/8305
摘要： The present invention relates to a process for immobilization of nucleic acid molecules on a substrate, wherein the substrate is treated with atomic oxygen plasma prior to immobilizing the nucleic acid molecules thereon. The invention is further related to immobilized nucleic acid molecules and uses thereof.
摘要翻译： 本发明涉及将核酸分子固定在基质上的方法，其中在将核酸分子固定在其上之前，用原子氧等离子体处理基底。 本发明还涉及固定的核酸分子及其用途。
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公开(公告)号：US09701629B2
公开(公告)日：2017-07-11
申请号：US11324416
申请日：2006-01-03
IPC分类号： B82Y10/00 , C07C323/60 , B82Y30/00 , C07C321/04 , C07C333/14 , H01B1/12 , H01L51/00 , H01L51/05 , C40B40/02
CPC分类号： C07C323/60 , B82Y10/00 , B82Y30/00 , C07C321/04 , C07C333/14 , C40B40/02 , H01B1/121 , H01L51/005 , H01L51/0052 , H01L51/0595
摘要： The invention relates to tuned multifunctional linker molecules for charge transport through organic-inorganic composite structures. The problem underlying the present invention is to provide multifunctional linker molecules for tuning the conductivity in nanoparticle-linker assemblies which can be used in the formation of electronic networks and circuits and thin films of nanoparticles. The problem is solved according to the invention by providing a multifunctional linker molecule of the general structure CON1-FUNC1-X-FUNC2-CON2 in which X is the central body of the molecule, FUNC1 and FUNC2 independently of each other are molecular groups introducing a dipole moment and/or capable of forming intermolecular and/or intramolecular hydrogen bonding networks, and CON 1 and CON 2 independently of each other are molecular groups binding to nanostructured units comprising metal and semiconductor materials.
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公开(公告)号：US20120016110A1
公开(公告)日：2012-01-19
申请号：US13243573
申请日：2011-09-23
申请人： William E. Ford , Jurina Wessels , Akio Yasuda
发明人： William E. Ford , Jurina Wessels , Akio Yasuda
CPC分类号： B82Y30/00 , B01J2219/00527 , B01J2219/00608 , B01J2219/00612 , B01J2219/00659 , B01J2219/00677 , B01J2219/00722 , C07B2200/11 , C07H21/00 , C12Q1/6806 , C40B40/06 , C12Q2523/113
摘要： The present invention relates to a method of immobilizing and stretching a nucleic acid on a silicon substrate, to nucleic acids and substrates prepared according to this method, to uses of the method and to uses of the nucleic acid and the substrate.
摘要翻译： 本发明涉及一种在硅底物上固定和拉伸核酸，根据该方法制备的核酸和底物，使用该方法和使用该核酸和底物的方法。
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