Analysis Chip With Reference Range, Kits and Methods of Analysis
    2.
    发明申请
    Analysis Chip With Reference Range, Kits and Methods of Analysis 失效
    具有参考范围,套件和分析方法的分析芯片

    公开(公告)号:US20080254448A1

    公开(公告)日:2008-10-16

    申请号:US10584916

    申请日:2004-12-23

    IPC分类号: C12Q1/68 G01N33/53

    摘要: Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this range comprising, immobilized on its surface and in a defined proportion P that is different and known for each spot relative to the other reference spots of said range: a probe reference molecule (PRM) permitting recognition and hybridization specifically to a defined target reference molecule (TRM), and/or an inert oligonucleotide molecule (IM) incapable of recognition and hybridization with said PRM, these molecules both being unable to immobilize said analyte or analytes. The method of the invention comprises the use of said chip with its reference range for analysis of said, at least one, analyte.

    摘要翻译: 至少一种分析物的分析芯片,所述芯片包含至少一个用于分析物特异性识别和固定的分析点; 和包括几个参考点的参考范围(G),每个参考点以规定的方式并且彼此独立地布置在所述芯片上,该范围的每个参考点包括固定在其表面上并以限定的比例P, 每个点相对于所述范围的其它参考点:探针参考分子(PRM),其允许特异性地与定义的靶参考分子(TRM)的识别和杂交,和/或不能识别和杂交的惰性寡核苷酸分子(IM) 所述PRM,这些分子都不能固定所述分析物或分析物。 本发明的方法包括使用其参考范围用于分析所述至少一种分析物的所述芯片。

    Analysis chip with reference range, kits and methods of analysis
    3.
    发明授权
    Analysis chip with reference range, kits and methods of analysis 失效
    分析芯片具有参考范围,套件和分析方法

    公开(公告)号:US08129113B2

    公开(公告)日:2012-03-06

    申请号:US10584916

    申请日:2004-12-23

    IPC分类号: C07H21/04 C12Q1/68 C12M1/36

    摘要: Analysis chip of at least one analyte, said chip comprising at least one analysis spot for recognition and immobilization specific to the analyte; and a reference range (G) comprising several reference spots each arranged on said chip in a defined manner and independently of one another, each reference spot of this range comprising, immobilized on its surface and in a defined proportion P that is different and known for each spot relative to the other reference spots of said range: a probe reference molecule (PRM) permitting recognition and hybridization specifically to a defined target reference molecule (TRM), and/or an inert oligonucleotide molecule (IM) incapable of recognition and hybridization with said PRM, these molecules both being unable to immobilize said analyte or analytes. The method of the invention comprises the use of said chip with its reference range for analysis of said, at least one, analyte.

    摘要翻译: 至少一种分析物的分析芯片,所述芯片包含至少一个用于分析物特异性识别和固定的分析点; 和包括几个参考点的参考范围(G),每个参考点以规定的方式并且彼此独立地布置在所述芯片上,该范围的每个参考点包括固定在其表面上并以限定的比例P, 每个点相对于所述范围的其它参考点:探针参考分子(PRM),其允许特异性地与定义的靶参考分子(TRM)的识别和杂交,和/或不能识别和杂交的惰性寡核苷酸分子(IM) 所述PRM,这些分子都不能固定所述分析物或分析物。 本发明的方法包括使用其参考范围用于分析所述至少一种分析物的所述芯片。

    Methods and devices for transporting and concentrating an analyte present in a sample
    4.
    发明授权
    Methods and devices for transporting and concentrating an analyte present in a sample 失效
    用于运送和浓缩样品中存在的分析物的方法和装置

    公开(公告)号:US07569398B2

    公开(公告)日:2009-08-04

    申请号:US10416207

    申请日:2001-11-27

    IPC分类号: G01N33/543 G01N33/553

    摘要: The present invention relates to a method of transporting an analyte present in a sample, to a method of concentrating an analyte present in a sample, and to a device for implementing these methods. In the method of transporting an analyte present in a sample of the present invention, a solution A in which the analyte is attached to magnetic particles is prepared from the sample; the solution A is introduced into a first container connected via a bottleneck to a second container; and the analyte attached to the magnetic particles is moved, by means of a magnetic system, from the first container to the second container via the bottleneck, the second container being filled with all or part of the solution A and/or with another solution.

    摘要翻译: 本发明涉及将存在于样品中的分析物输送到浓缩样品中存在的分析物的方法以及用于实施这些方法的装置。 在本发明的样品中存在的分析物的输送方法中,从样品制备分析物附着在磁性粒子上的溶液A; 将溶液A引入通过瓶颈连接到第二容器的第一容器中; 并且附着到磁性颗粒上的分析物通过瓶颈从第一容器移动到第二容器,第二容器被全部或部分溶液A和/或另外的溶液填充。