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公开(公告)号：US08182763B2
公开(公告)日：2012-05-22
申请号：US12178584
申请日：2008-07-23
申请人： Patrick Duffy , Kerry Wilson , Kalyan Handique , Jeff Williams
发明人： Patrick Duffy , Kerry Wilson , Kalyan Handique , Jeff Williams
IPC分类号： B01L9/06
CPC分类号： C12N15/1003 , B01L3/5082 , B01L7/52 , B01L9/06 , B01L9/527 , B01L2200/16 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/0099 , G01N35/026 , G01N35/1002 , G01N2035/00772 , G01N2035/00801 , G01N2035/00881 , G01N2035/0493
摘要： A rack for holding samples and various reagents, wherein the rack may be used for loading the samples and reagents prior to using the reagents. The rack accepts complementary reagent holders, each of which contain a set of reagents for carrying out a predetermined processing operation, such as preparing biological samples for amplifying and detecting polynucleotides extracted from the samples.
摘要翻译： 用于容纳样品和各种试剂的支架，其中，在使用试剂之前，可以使用支架装载样品和试剂。 机架接受互补的试剂保持器，每个试剂容器包含用于进行预定处理操作的一组试剂，例如制备用于扩增和检测从样品提取的多核苷酸的生物样品。
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公开(公告)号：US20120258463A1
公开(公告)日：2012-10-11
申请号：US13474980
申请日：2012-05-18
申请人： Patrick Duffy , Kerry Wilson , Kalyan Handique , Jeff Williams
发明人： Patrick Duffy , Kerry Wilson , Kalyan Handique , Jeff Williams
CPC分类号： C12N15/1003 , B01L3/5082 , B01L7/52 , B01L9/06 , B01L9/527 , B01L2200/16 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/0099 , G01N35/026 , G01N35/1002 , G01N2035/00772 , G01N2035/00801 , G01N2035/00881 , G01N2035/0493 , Y10T436/113332
摘要： A rack for holding samples and various reagents, wherein the rack may be used for loading the samples and reagents prior to using the reagents. The rack accepts complementary reagent holders, each of which contain a set of reagents for carrying out a predetermined processing operation, such as preparing biological samples for amplifying and detecting polynucleotides extracted from the samples.
摘要翻译： 用于容纳样品和各种试剂的支架，其中，在使用试剂之前，可以使用支架装载样品和试剂。 机架接受互补的试剂保持器，每个试剂容器包含用于进行预定处理操作的一组试剂，例如制备用于扩增和检测从样品提取的多核苷酸的生物样品。
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公开(公告)号：US20090136386A1
公开(公告)日：2009-05-28
申请号：US12178584
申请日：2008-07-23
申请人： Patrick Duffy , Kerry Wilson , Kalyan Handique , Jeff Williams
发明人： Patrick Duffy , Kerry Wilson , Kalyan Handique , Jeff Williams
IPC分类号： B01L9/06
CPC分类号： C12N15/1003 , B01L3/5082 , B01L7/52 , B01L9/06 , B01L9/527 , B01L2200/16 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/0099 , G01N35/026 , G01N35/1002 , G01N2035/00772 , G01N2035/00801 , G01N2035/00881 , G01N2035/0493
摘要： A rack for holding samples and various reagents, wherein the rack may be used for loading the samples and reagents prior to using the reagents. The rack accepts complementary reagent holders, each of which contain a set of reagents for carrying out a predetermined processing operation, such as preparing biological samples for amplifying and detecting polynucleotides extracted from the samples.
摘要翻译： 用于容纳样品和各种试剂的支架，其中，在使用试剂之前，可以使用支架装载样品和试剂。 机架接受互补的试剂保持器，每个试剂容器包含用于进行预定处理操作的一组试剂，例如制备用于扩增和检测从样品提取的多核苷酸的生物样品。
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公开(公告)号：US09186677B2
公开(公告)日：2015-11-17
申请号：US12218498
申请日：2008-07-14
申请人： Jeff Williams , Kerry Wilson , Kalyan Handique
发明人： Jeff Williams , Kerry Wilson , Kalyan Handique
CPC分类号： B01L3/502761 , B01L3/0275 , B01L3/5027 , B01L3/52 , B01L7/52 , B01L9/06 , B01L9/527 , B01L2200/027 , B01L2200/10 , B01L2200/147 , B01L2200/148 , B01L2200/16 , B01L2300/021 , B01L2300/045 , B01L2300/06 , B01L2300/0627 , B01L2300/0681 , B01L2300/0816 , B01L2300/0832 , B01L2300/0867 , B01L2300/087 , B01L2300/0887 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B01L2300/1861 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0677 , B01L2400/0683 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/026 , G01N2035/00881 , G01N2035/0425 , G01N2035/0436
摘要： The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.
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5.发明申请INTEGRATED APPARATUS FOR PERFORMING NUCLEIC ACID EXTRACTION AND DIAGNOSTIC TESTING ON MULTIPLE BIOLOGICAL SAMPLES 有权用于在多种生物样品上进行核酸提取和诊断测试的综合设备公开(公告)号：US20120171759A1
公开(公告)日：2012-07-05
申请号：US13417108
申请日：2012-03-09
申请人： Jeff Williams , Kalyan Handique , Kerry Wilson
发明人： Jeff Williams , Kalyan Handique , Kerry Wilson
CPC分类号： B01L7/52 , B01L3/5027 , B01L3/5085 , B01L9/06 , B01L9/527 , B01L2200/027 , B01L2200/10 , B01L2200/147 , B01L2200/148 , B01L2200/16 , B01L2300/021 , B01L2300/045 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0887 , B01L2300/1822 , B01L2300/1827 , B01L2300/1861 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0677 , B01L2400/0683 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/026 , G01N2035/00881 , G01N2035/0436 , G01N2035/103
摘要： The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.
摘要翻译： 本文描述的技术通常涉及用于从多个样品，特别是来自生物样品中提取多核苷酸的系统，另外还涉及随后扩增和检测提取的多核苷酸的系统。 该技术更特别涉及在微流体通道内的多个目的核苷酸样品上进行PCR并检测这些核苷酸的微流体系统。
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公开(公告)号：USD665095S1
公开(公告)日：2012-08-07
申请号：US29389681
申请日：2011-04-14
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公开(公告)号：USD637737S1
公开(公告)日：2011-05-10
申请号：US29363666
申请日：2010-06-11
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公开(公告)号：US09259734B2
公开(公告)日：2016-02-16
申请号：US13417108
申请日：2012-03-09
申请人： Jeff Williams , Kalyan Handique , Kerry Wilson
发明人： Jeff Williams , Kalyan Handique , Kerry Wilson
IPC分类号： B01L7/00 , B01L3/00 , B01L9/00 , F16K99/00 , B01L9/06 , G01N35/02 , G01N35/04 , G01N35/00 , G01N35/10
CPC分类号： B01L7/52 , B01L3/5027 , B01L3/5085 , B01L9/06 , B01L9/527 , B01L2200/027 , B01L2200/10 , B01L2200/147 , B01L2200/148 , B01L2200/16 , B01L2300/021 , B01L2300/045 , B01L2300/0681 , B01L2300/0816 , B01L2300/0867 , B01L2300/087 , B01L2300/0887 , B01L2300/1822 , B01L2300/1827 , B01L2300/1861 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0677 , B01L2400/0683 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/026 , G01N2035/00881 , G01N2035/0436 , G01N2035/103
摘要： The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.
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9.发明申请Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples 有权用于对多个生物样品进行核酸提取和诊断测试的综合装置公开(公告)号：US20090221059A1
公开(公告)日：2009-09-03
申请号：US12218498
申请日：2008-07-14
申请人： Jeff Williams , Kerry Wilson , Kalyan Handique
发明人： Jeff Williams , Kerry Wilson , Kalyan Handique
CPC分类号： B01L3/502761 , B01L3/0275 , B01L3/5027 , B01L3/52 , B01L7/52 , B01L9/06 , B01L9/527 , B01L2200/027 , B01L2200/10 , B01L2200/147 , B01L2200/148 , B01L2200/16 , B01L2300/021 , B01L2300/045 , B01L2300/06 , B01L2300/0627 , B01L2300/0681 , B01L2300/0816 , B01L2300/0832 , B01L2300/0867 , B01L2300/087 , B01L2300/0887 , B01L2300/18 , B01L2300/1822 , B01L2300/1827 , B01L2300/1861 , B01L2400/0442 , B01L2400/0481 , B01L2400/0487 , B01L2400/0611 , B01L2400/0677 , B01L2400/0683 , F16K99/0001 , F16K99/003 , F16K99/0032 , F16K99/0044 , F16K99/0061 , F16K2099/0084 , G01N35/026 , G01N2035/00881 , G01N2035/0425 , G01N2035/0436
摘要： The technology described herein generally relates to systems for extracting polynucleotides from multiple samples, particularly from biological samples, and additionally to systems that subsequently amplify and detect the extracted polynucleotides. The technology more particularly relates to microfluidic systems that carry out PCR on multiple samples of nucleotides of interest within microfluidic channels, and detect those nucleotides.
摘要翻译： 本文描述的技术通常涉及用于从多个样品，特别是来自生物样品中提取多核苷酸的系统，另外还涉及随后扩增和检测提取的多核苷酸的系统。 该技术更特别涉及在微流体通道内的多个目的核苷酸样品上进行PCR并检测这些核苷酸的微流体系统。
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公开(公告)号：US09701957B2
公开(公告)日：2017-07-11
申请号：US12218416
申请日：2008-07-14
CPC分类号： C12N15/1013 , C07H1/08 , C12Q1/6813
摘要： A holder for reagents, such as may be used for transporting the reagents and for carrying out processing operations on biological samples with the reagents. The holders typically hold reagents for amplifying polynucleotides extracted from the samples. The holder comprises a connecting member; a process tube affixed to the connecting member and having an aperture located in the connecting member; at least one socket, located in the connecting member, and configured to accept a pipette tip; two or more reagent tubes disposed on the underside of the connecting member, each having an inlet aperture located in the connecting member; and one or more receptacles, located in the connecting member and each being configured to receive a reagent tube. Also described are reagent tubes configured with stellated shaped patterns, on their bottom interior surfaces, configured to facilitate complete or near-complete withdrawal of fluid from the tube, via a pipette tip.
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