摘要:
The present invention relates to the provision of a polynucleotide comprising one or more functional fragments of a biosynthetic gene cluster involved in the production of a compound of formula (I) or (I′). The present invention also provides a method of preparing a compound of formula (I) or (I′) or of formula (II) to (VII), (XI) to (XIV) and (XVII) and (XVIII). Moreover, the use of such compound as a pharmaceutical composition is also provided in the present invention.
摘要:
A resource broker agent may be configured to monitor computing resources available on a computing device. The resource broker agent may be further configured to request additional computing resources in response to detecting a request to perform a computing task that cannot be adequately performed with the computing resources currently available on the computing device. The additional computing resources may be requested from one or more remote resource providers via a network. The additional computing resources may comprise remote execution of portions of the computing task. The resource broker agent may be further configured to perform the requested computing task by use of a virtualized computing environment of the computing device.
摘要:
The invention relates generally to novel macrolactams and their analogs, to processes for the preparation of these novel macrolactams, to pharmaceutical compositions comprising the novel macrolactams; and to methods of using the novel macrolactams to treat or inhibit various disorders.
摘要:
An imaging pixel array and associated method and system are disclosed in which the array contains first pixels each having a first photo-conversion device, and second pixels each having a first photo-conversion device and a second photo-conversion device. The first photo-conversion devices are configured to acquire an image during a first integration period. The second photo-conversion devices are configured to acquire a plurality of images during the first integration period. A circuit uses the plurality of image signals and determines from them relative motion between the array and an image during a portion of the first integration period and provides a signal representing the motion which is used for image stabilization.
摘要:
A microprocessor system in which an array of processors communicates more efficiently through the use of a worker mode function. Processors that are not currently executing code remain in an inactive but alert state until a task is sent to them by an adjacent processor. Processors can also be programmed to temporarily suspend a task to check for incoming tasks or messages.
摘要:
A linear PLL includes a VCO with first and second tuning elements. The first tuning element is adjusted in proportion to the phase error between an input signal and a VCO signal and the second tuning element is adjusted by an integral function of the phase error. By configuring the VCO with separate tuning elements that are separately adjusted in proportion to the phase error and by an integral function of the phase error, the 3 dB bandwidth frequency of the linear PLL depends primarily on the phase detector gain and the VCO gain that is contributed from the proportional adjustment. A linear PLL with separate proportional and integral tuning elements can be designed to exhibit a relatively constant gain over a relatively large frequency range.
摘要:
A packaged IC includes an IC die with signal and signal complement traces positioned relative to each other to maximize broadside coupling for a matching impedance. The signal and signal complement traces are electrically connected to transmission or receive channels of the IC die. Use of a broadside coupled trace configuration alleviates routing congestion in an IC package and permits an IC to accommodate a greater number of channels within a given surface area than is possible under the prior art.
摘要:
Described is a circuit for receiving a differential input signal at two substantially symmetrically built up current paths and for providing an output signal therefrom. At least one current path comprises means for adjusting the timing information of the input signal to the timing information of the output signal. The adjustment can be accomplished by modifying a voltage level in the respective current path until the timing information of the output signals at least substantially represents the timing information of the input signal, e.g. by modifying an impedance or a current in the respective current path. The adjusting of the timing information is executed by applying a defined input signal with a known timing information, comparing the timing information of the resulting output signal with the timing information of the input signal, and modifying at least one voltage level in at least one of the current paths until the timing information of the output and input signals at least substantially match.
摘要:
A coupling system attaches a device such as a blank adaptor or a sound suppressor to the flash hider of a firearm. The device is slid over the flash hider until a set of flat surfaces on it are aligned with a set of holes in the device. Camming latches are held in the holes in the device. The collar carried by the device is then threadably advanced to a locking position with respect to the device where it presses the camming latches into secure engagement with the flat surfaces on the flash hider. Unthreading the collar to the unlocked position allows the camming latches to be moved radially when the device is to be removed or rotated. A spring lock prevents the collar from rotating during use, particularly during firing of the firearm but may be released to rotate the collar between locked and unlocked positions.
摘要:
A microprocessor executes at 100 native MIPS peak performance with a 100-MHz internal clock frequency. Central processing unit (CPU) instruction sets are hardwired, allowing most instructions to execute in a single cycle. A “flow-through” design allows the next instruction to start before the prior instruction completes, thus increasing performance. A microprocessing unit (MPU) contains 52 general-purpose registers, including 16 global data registers, an index register, a count register, a 16-deep addressable register/return stack, and an 18-deep operand stack. Both stacks contain an index register in the top elements, are cached on chip, and when required, automatically spill to and refill from external memory. The stacks minimize the data movement and also minimize memory access during procedure calls, parameter passing, and variable assignments. Additionally, the MPU contains a mode/status register and 41 locally addressed registers for I/O, control, configuration, and status. The CPU contains both a high-performance, zero-operand, dual-stack architecture MPU, and an input-output processor (IOP) that executes instructions to transfer data, count events, measure time, and perform other timing-dependent functions. A zero-operand stack architecture eliminates operand bits. Stacks also minimize register saves and loads within and across procedures, thus allowing shorter instruction sequences and faster-running code. Instructions are simple to decode and execute, allowing the MPU and IOP to issue and complete instructions in a single clock cycle—each at 100 native MIPS peak execution. Using 8-bit opcodes, the CPU obtains up to four instructions from memory each time an instruction fetch or pre-fetch is performed. These instructions can be repeated without rereading them from memory. This maintains high performance when connected directly to DRAM, without a cache.