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1.发明授权公开(公告)号：US07214478B2
公开(公告)日：2007-05-08
申请号：US10475634
申请日：2003-02-20
IPC分类号： C12Q1/68
CPC分类号： B01L3/502707 , B01L2300/12 , B01L2300/16 , B01L2400/0415 , G01N33/545 , G01N33/552
摘要： The invention concerns a component for biological or biochemical analysis microsystems formed from a support and having at least one chemically functionalised surface zone, in order to allow in said zone the formation of a chemistry for anchoring biological or biochemical elements, and/or electrically, in order to allow in said zone the formation of electrical charges. The support comprises at least one part (21) formed of a composite material, said composite material being a mixture of at least one inert material and at least one chemically and/or electrically functionalisable material to provide said functionalised surface zone.
摘要翻译： 本发明涉及由支持物形成并具有至少一个化学官能化表面区域的生物或生物化学分析微系统的组件，以便在所述区域中形成用于锚定生物或生物化学元素的化学物质，和/或电气地 为了允许在所述区域中形成电荷。 支撑体包括由复合材料形成的至少一个部分（21），所述复合材料是至少一种惰性材料和至少一种化学和/或电学上可用的材料的混合物，以提供所述官能化的表面区域。
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公开(公告)号：US20060068450A1
公开(公告)日：2006-03-30
申请号：US10533947
申请日：2003-11-12
IPC分类号： G01N33/542 , C12M1/34 , G01N33/53
CPC分类号： G01N30/6095 , B01D15/22 , B01J2219/00317 , B01J2219/00466 , B01J2219/00468 , B01J2219/00648 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/00745 , B01J2219/00747 , B01L3/5027 , B81B2201/051 , C40B30/08 , C40B40/06 , C40B40/10 , C40B40/18 , C40B60/14
摘要： The invention relates to a micro-system intended to receive beads and to obtain a precise positioning of the beads at preset locations in the micro-system. This micro-system comprises a tank that has a cavity, the cavity being fitted with blocking elements allowing the beads to be ordered and stacked in the interstices between the blocking elements, the interstices constituting the preset locations. It also comprises a cap anchored hermetically to the tank and input means and output means allowing a fluid to flow in the cavity. The invention also relates to the implementation and use of the bead-filled micro-system.
摘要翻译： 本发明涉及一种用于接收珠粒并获得珠子在微系统中的预设位置的精确定位的微系统。 该微系统包括具有空腔的腔体，空腔配有阻挡元件，允许将珠子排序并堆叠在阻挡元件之间的空隙中，构成预设位置的间隙。 它还包括一个盖住气罐的盖子和输入装置和允许流体在空腔中流动的输出装置。 本发明还涉及珠填充微系统的实现和使用。
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3.发明授权Microreactor, process for the preparation thereof, and process for carrying out a biochemical or biological reaction 有权微反应器，其制备方法以及进行生物化学或生物反应的方法公开(公告)号：US08192980B2
公开(公告)日：2012-06-05
申请号：US10514066
申请日：2003-05-16
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00828 , B01J2219/00889 , B01L3/5027 , B01L2200/12 , B01L2300/0636 , B01L2300/0864 , B01L2400/049 , G01N30/6095
摘要： A microreactor is shown having an inlet or feed channel, an inlet or feed zone for a flow of fluid, a reaction zone, an outlet zone and an outlet or evacuation channel, the zones and channels being in fluid communication, and at least one compound such as an enzyme capable of producing a biological or biochemical reaction with at least one constituent of the flow of fluid, the compound being attached to the surfaces of the inlet zone, reaction zone, and outlet zone.
摘要翻译： 示出了微反应器具有入口或进料通道，用于流体流动的入口或进料区域，反应区域，出口区域和出口或排出通道，所述区域和通道是流体连通的，以及至少一种化合物 例如能够与流体流动的至少一种成分产生生物或生物化学反应的酶，所述化合物附着到入口区域，反应区域和出口区域的表面。
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公开(公告)号：US07469587B2
公开(公告)日：2008-12-30
申请号：US11410971
申请日：2006-04-26
申请人： Jérôme Dido , Pierre Loisel , Alain Renault , Philippe Combette , Johann Courteaud , Alain Giani
发明人： Jérôme Dido , Pierre Loisel , Alain Renault , Philippe Combette , Johann Courteaud , Alain Giani
IPC分类号： G01P15/00
CPC分类号： G01P15/008
摘要： The acceleration measurement system has a first thermal cell optimized in sensitivity and a second thermal cell optimized in passband, which cells are connected to inputs of a servo-control loop including an amplifier presenting gain that varies as a function of input signal frequency.
摘要翻译： 加速度测量系统具有灵敏度优化的第一热电池单元和通带优化的第二热电池单元，所述第二热电池单元连接到伺服控制回路的输入端，所述伺服控制回路包括作为输入信号频率变化的增益。
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5.发明申请Microreactor, method for preparing same, and method for producing a biochemical or biological reaction 有权微反应器，其制备方法以及生物化学或生物反应的生产方法公开(公告)号：US20060051858A1
公开(公告)日：2006-03-09
申请号：US10514066
申请日：2003-05-16
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00828 , B01J2219/00889 , B01L3/5027 , B01L2200/12 , B01L2300/0636 , B01L2300/0864 , B01L2400/049 , G01N30/6095
摘要： Microreactor comprising an inlet or feed channel, an inlet or feed zone (1) for a flow of fluid, a reaction zone (2), an outlet zone (3) and an outlet or evacuation channel, said zones (1, 2, 3) and channels (46, 48) being in fluid communication, and at least one compound such as an enzyme capable of producing a biological or biochemical reaction with at least one constituent of said flow of fluid, said compound being attached to the surfaces of said inlet zone (1), reaction zone (2), and outlet zone (3).
摘要翻译： 微反应器包括入口或进料通道，用于流体流动的入口或进料区（1），反应区（2），出口区（3）和出口或抽空通道，所述区（1,2,3） ）和通道（46,48）处于流体连通，以及至少一种化合物，例如能够与所述流体流的至少一种成分产生生物或生物化学反应的酶，所述化合物附着到所述 入口区（1），反应区（2）和出口区（3）。
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6.发明申请Method for reproduction of a compnent with a micro-joint and component produced by said method 审中-公开通过所述方法制造的具有微接头的部件和部件的再生方法公开(公告)号：US20060048885A1
公开(公告)日：2006-03-09
申请号：US10533296
申请日：2003-11-04
CPC分类号： B29C65/526 , B01J19/0093 , B01J2219/00783 , B01J2219/00833 , B01J2219/0086 , B01L3/502707 , B01L2200/0689 , B01L2200/12 , B01L2300/044 , B01L2300/0819 , B29C35/00 , B29C66/0242 , B29C66/112 , B29C66/1122 , B29C66/131 , B29C66/5346 , B29C66/54 , B29C66/71 , B29L2031/756 , B32B37/1284 , B81B2201/0214 , B81B2201/058 , B81C1/00119 , B81C1/00357 , B81C3/008 , B81C2201/019 , B81C2201/0191 , B29K2083/00
摘要： The method for production of a component with a micro-joint comprises a first step of deposition of a layer of polymer designed to constitute an assembly joint on a transfer substrate, a second step of bringing the polymer layer into contact with a micro-structured substrate and a third step of removing the transfer substrate. Due to the difference of the chemical affinity between the polymer layer and the transfer substrate on the one hand and the chemical affinity between the polymer layer and the micro-structured substrate on the other hand, the zones of the polymer layer, which are in contact with the micro-structured substrate during the second step, remain on the micro-structured substrate after the third step. These zones constitute the assembly joint.
摘要翻译： 用于生产具有微接头的部件的方法包括：第一步骤，沉积设置成在转印基板上构成组装接头的聚合物层;第二步骤，使聚合物层与微结构基材接触 以及去除转印衬底的第三步骤。 由于聚合物层和转印基板之间的化学亲和力的差异以及聚合物层和微结构基板之间的化学亲和力，所以聚合物层的接触区域 在第二步骤中，微结构的衬底在第三步之后保留在微结构衬底上。 这些区域构成组装接头。
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7.发明授权Device and method for determination of physical parameters for a two-phase mix by propagation of an acoustic wave in the continuous phase of the two-phase mix 失效用于通过在两相混合物的连续相中的声波的传播来确定两相混合物理参数的装置和方法公开(公告)号：US06560548B1
公开(公告)日：2003-05-06
申请号：US09720725
申请日：2001-01-24
IPC分类号： G10K1500
CPC分类号： G01N29/221 , G01N29/024 , G01N29/2456 , G01N2291/011 , G01N2291/0222 , G01N2291/02416 , G01N2291/02818 , G01N2291/02854
摘要： A device measures the propagation time for an acoustic wave in a continuous phase of a two-phase mix (28) comprising the continuous phase and a dispersed phase forming droplets (40) in the continuous phase. The device comprises an electro-acoustic transducer (12) capable of emitting acoustic waves (30) and outputting a reception signal of reflected acoustic waves, a signal pulse generator capable of determining a propagation time starting from signals output by the transducer, and an acoustic lens for focusing acoustic waves and the frequency of the acoustic waves being adjusted to cause reflection of the waves on the droplets of the dispersed phase, essentially located within a focusing area.
摘要翻译： 器件测量在包括连续相的两相混合物（28）的连续相中的声波的传播时间和在连续相中形成液滴（40）的分散相。 该装置包括能够发出声波（30）并输出反射声波的接收信号的电声换能器（12），能够从由换能器输出的信号确定传播时间的信号脉冲发生器和声学 透镜用于聚焦声波，并且声波的频率被调整以引起波在分散相的液滴上的反射，基本上位于聚焦区域内。
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