Abstract:
Methods and apparatuses for measuring a light absorbance are provided. The method measures light absorbance of at least one detection chamber of a microfluidic device, including the detection chamber and at least one reference chamber. The detection chamber may accommodate a test subject. The method includes detecting a plurality of reference transmitted light intensities for the at least one reference chamber and estimating a value between the plurality of reference transmitted light intensities through nonlinear approximation. The estimated value is then applied to light absorbance measurement of the detection chamber to reduce a light absorbance error of the detection chamber.
Abstract:
A microfluidic device and control method thereof are provided. The control method of the microfluidic device includes detecting a background signal from a chamber in which a reaction product formed by combining an analyte and a marking material is not accommodated, detecting a detection signal from a chamber in which the reaction product is accommodated, and compensating for the detection signal using the background signal.
Abstract:
A test device, test system, and control method of the test device, which defines a light irradiating area in a reactor to prevent a decrease in magnitude of a detected signal that may result due to scattering of light that has penetrated other area of the reactor than an area containing an object for detection and improve a dynamic range. A test device may include a light source configured to irradiate light; a reactor configured to include at least one first area to contain an object for detection; and a photo detector configured to receive light that has been irradiated from the light source and has passed the reactor that contains the object for detection, wherein the light source is configured to limitedly irradiate the light to the first area of the reactor.
Abstract:
A test apparatus and a control method thereof are provided. The test apparatus is configured to test a sample in a reactor. The test apparatus includes at least one light emitter configured to emit light to chambers of the reactor, a light receiver configured to receive light passed through the chambers while scanning the chambers, and a processor configured to determine a position or an area of a chamber among the chambers, based on light receiving positions of the light receiver, and respective intensities of the received light. The processor is further configured to measure an optical density of light passed through the determined position or the determined area of the chamber.
Abstract:
A test apparatus for measuring the temperature of a reactor using a thermochromic pigment, and a method for controlling the test apparatus are disclosed, based on a technology for irradiating light of different wavelengths on a thermochromic pigment accommodated in a reactor and estimating temperature of the reactor using a difference between absorbance values corresponding to the light of the different wavelengths. The test apparatus includes at least one light emitter configured to irradiate light of different wavelengths onto a chamber included in the reactor, a light receiver configured to receive the light that propagates through the chamber, and a controller configured to measure absorbance values of the thermochromic pigment in correspondence to the different wavelengths of the light, to calculate a difference between the measured absorbance values, and to determine a temperature of the reactor in correspondence to the calculated difference between the absorbance values.
Abstract:
A fluid analysis cartridge includes a reference well including a macromolecular coloring reagent having an optical characteristic that varies according to a thickness of the reference well, and a test well including a test reagent having an optical characteristic that varies according to a concentration of a component of a fluid sample that reacts with the test reagent and a thickness of the test well.
Abstract:
A microfluidic device includes a chamber configured to accommodate a sample and air, and a detection device provided with a light emitter configured to emit light towards the chamber on a light transmission path and a light receiver configured to receive the light, and further configured to measure an optical density of the chamber to determine whether the sample is accommodated in the chamber based on the received light. A boundary between the sample and the air accommodated in the chamber is provided on the light transmission path.
Abstract:
A microfluidic apparatus and a microfluidic system including the same are provided. The microfluidic system includes a microfluidic apparatus including a platform, the platform including an inlet configured to receive a sample, a chamber configured to accommodate the sample received through the inlet, and a channel connecting the chamber to the inlet, a pressurizing apparatus configured to move the sample from the inlet to the chamber through the channel by pressurizing the inlet, and a detection apparatus configured to detect the sample inside of the chamber.