公开(公告)号：US5514406A

公开(公告)日：1996-05-07

申请号：US325309

申请日：1994-12-20

申请人： Seiichiro Aoe ,  Sachiko Yahagi ,  Masatoshi Yahiro ,  Toshimitsu Yoshioka ,  Hiroaki Konishi ,  Mototake Murakami ,  Masami Kawanari

发明人： Seiichiro Aoe ,  Sachiko Yahagi ,  Masatoshi Yahiro ,  Toshimitsu Yoshioka ,  Hiroaki Konishi ,  Mototake Murakami ,  Masami Kawanari

IPC分类号： A21D2/16 ,  A21D13/00 ,  A21D13/06 ,  A21D13/08 ,  A23D7/00 ,  A23D9/00 ,  A23D9/007 ,  A23D9/05 ,  A23G3/34 ,  A23G9/32 ,  A23G9/44 ,  A23G9/52 ,  A23L33/20

CPC分类号： A23G3/346 ,  A21D13/068 ,  A21D2/165 ,  A23D7/001 ,  A23D9/00 ,  A23D9/05 ,  A23G9/52 ,  A23G2200/08

摘要： An oil and fat composition having decreased digestive and absorptive properties comprising an oil and fat composition containing 50% or more tristearin is disclosed. In addition, the oil and fat composition is preferably powdered to have a particle size of 100 .mu.m or less. When beverages and foods containing oil and fat are made, nutritive efficiency may be decreased by using the oil and fat composition of the present invention in place of normally ingested oils and fats. Therefore, the oil and fat composition of the present invention is useful as a material for designer's and pharmaceutical foods.

摘要翻译： PCT No.PCT / JP94 / 00277 Sec。 371日期1994年12月20日第 102（e）1994年12月20日授权PCT 1994年2月23日提交。公开了包含含有50％或更多三硬脂酸甘油酯的油脂组合物具有降低的消化吸收性能的油脂组合物。 此外，油脂组合物优选粉末化以具有100μm以下的粒径。 当制备含有油和脂肪的饮料和食品时，通过使用本发明的油脂组合物代替通常摄取的油和脂肪可以降低营养效率。 因此，本发明的油脂组合物可用作设计者和药用食品的材料。

公开(公告)号：US08920822B2

公开(公告)日：2014-12-30

申请号：US12947891

申请日：2010-11-17

申请人： Ken Kato ,  Noriko Ueda ,  Susumu Miura ,  Toshimitsu Yoshioka

发明人： Ken Kato ,  Noriko Ueda ,  Susumu Miura ,  Toshimitsu Yoshioka

IPC分类号： A61K8/02 ,  A61Q19/08 ,  A23J7/00 ,  A23K1/16 ,  A23L1/30 ,  A61K8/68 ,  A61K31/688 ,  A61Q19/00

CPC分类号： A61Q19/08 ,  A23J7/00 ,  A23K20/158 ,  A23L33/10 ,  A23L33/115 ,  A23V2002/00 ,  A61K8/68 ,  A61K31/688 ,  A61K2800/92 ,  A61Q19/00 ,  A23V2250/1846 ,  A23V2200/318

摘要： A skin beautifier contains sphingomyelin, which is a phospholipid, as an effective ingredient. In addition, skin-beautifying food or feed contains sphingomyelin as an effective ingredient. The present invention provides a skin beautifier and skin-beautifying food or feed supplying effects on beauty, such as skin-moisturizing and protecting effects, skin-roughness-preventing and improving effects, and a wrinkle-preventing effect, by oral ingestion thereof.

摘要翻译： 皮肤美容师含有作为有效成分的磷脂磷角蛋白。 另外，皮肤美化食品或饲料含有鞘磷脂作为有效成分。 本发明提供一种通过口服摄取，提供美容效果，例如皮肤保湿和保护效果，皮肤粗糙度防止和改善效果以及防皱效果的皮肤美容和美容美容食品。

公开(公告)号：US08158403B2

公开(公告)日：2012-04-17

申请号：US12306975

申请日：2007-06-26

申请人： Mari Miura ,  Yasuyuki Seto ,  Masayuki Watanabe ,  Toshimitsu Yoshioka

发明人： Mari Miura ,  Yasuyuki Seto ,  Masayuki Watanabe ,  Toshimitsu Yoshioka

IPC分类号： A23C9/12 ,  C12N1/20 ,  C12N1/38

CPC分类号： C12N1/20 ,  A23C9/12 ,  A23C9/1232 ,  A23C9/1234 ,  A23C15/123 ,  C12N1/38

摘要： A dead cell of a lactic acid bacterium or a culture containing the dead cell of a lactic acid bacterium is added to the dairy products such as yogurt, cheese, milk beverage or the like in an amount of 0.001 wt % or more in dry weight of the dead cell, therefore, it is possible to enhance the growth of a lactic acid bacterium, to shorten the time required for fermentation, and to improve the viability of a lactic acid bacterium during storage over a long period, without affecting the flavor or production cost of the dairy product.

摘要翻译： 将乳酸菌的死细胞或含有乳酸菌的死细胞的培养物加入到酸奶，奶酪，奶饮料等乳制品中，其干重为0.001重量％以上 因此，可以增加乳酸菌的生长，缩短发酵所需的时间，并且在长时间保存期间提高乳酸菌的生存力，而不影响风味或生产 乳制品成本。

公开(公告)号：US20100135941A1

公开(公告)日：2010-06-03

申请号：US12530617

申请日：2008-03-10

申请人： Tatsuya Watanabe ,  Ken Kato ,  Hiroshi Ueno ,  Yuko Haruta ,  Noriko Ueda ,  Toshimitsu Yoshioka

发明人： Tatsuya Watanabe ,  Ken Kato ,  Hiroshi Ueno ,  Yuko Haruta ,  Noriko Ueda ,  Toshimitsu Yoshioka

IPC分类号： A61K8/64 ,  C07K5/06 ,  C07K5/08 ,  C07K5/10 ,  C07K7/06 ,  A61K38/05 ,  A61K38/06 ,  A61K38/07 ,  A61K38/08 ,  A61Q1/00 ,  A61P17/00

CPC分类号： A61K35/20 ,  A23C9/1526 ,  A23K20/147 ,  A23K50/40 ,  A23L2/52 ,  A23L33/18 ,  A23L33/19 ,  A61K8/64 ,  A61K38/00 ,  A61K38/018 ,  A61K2800/92 ,  A61Q19/02

摘要： A skin-whitening agent offering an excellent whitening effect and being effective in preventing and treating age spots, freckles, etc., where such skin-whitening agent contains as its effective ingredient a whey protein hydrolyzate characterized by a molecular weight distribution of 10 kDa or less, main peak of 200 Da to 3 kDa, APL (average peptide-chain length) of 2 to 8, free amino acid content of 20% or less, and antigenicity of one-ten thousandth of β-lactoglobulin or less, as well as a cosmetic, drink or food, feed, pharmaceutical preparation or other skin-whitening product containing such skin-whitening agent.

摘要翻译： 一种美白剂，其具有优异的美白效果，并有效预防和治疗老年斑，雀斑等，其中这样的皮肤增白剂作为其有效成分含有以10kDa分子量分布为特征的乳清蛋白水解产物，或 较少的主峰为200Da至3kDa，APL（平均肽链长度）为2至8，游离氨基酸含量为20％或更低，抗原性为万分之一以上的乳球蛋白或更少，为 以及化妆品，饮料或食品，饲料，药物制剂或含有这种皮肤增白剂的其它皮肤美白产品。

公开(公告)号：US20090317892A1

公开(公告)日：2009-12-24

申请号：US12306975

申请日：2007-06-26

申请人： Mari Miura ,  Yasuyaki Seto ,  Masayuki Watanabe ,  Toshimitsu Yoshioka

发明人： Mari Miura ,  Yasuyaki Seto ,  Masayuki Watanabe ,  Toshimitsu Yoshioka

IPC分类号： C12N1/38

CPC分类号： C12N1/20 ,  A23C9/12 ,  A23C9/1232 ,  A23C9/1234 ,  A23C15/123 ,  C12N1/38

摘要： A dead cell of a lactic acid bacterium or a culture containing the dead cell of a lactic acid bacterium is added to the dairy products such as yogurt, cheese, milk beverage or the like in an amount of 0.001 wt % or more in dry weight of the dead cell, therefore, it is possible to enhance the growth of a lactic acid bacterium, to shorten the time required for fermentation, and to improve the viability of a lactic acid bacterium during storage over a long period, without affecting the flavor or production cost of the dairy product.

摘要翻译： 将乳酸菌的死细胞或含有乳酸菌的死细胞的培养物加入到酸奶，奶酪，乳饮料等乳制品中，其干重为0.001重量％以上 因此，可以增加乳酸菌的生长，缩短发酵所需的时间，并且在长时间保存期间提高乳酸菌的生存力，而不影响风味或生产 乳制品成本。

公开(公告)号：US20090069217A1

公开(公告)日：2009-03-12

申请号：US11918471

申请日：2005-04-13

申请人： Ken Kato ,  Noriko Ueda ,  Miyako Tanaka ,  Toshimitsu Yoshioka

发明人： Ken Kato ,  Noriko Ueda ,  Miyako Tanaka ,  Toshimitsu Yoshioka

IPC分类号： A61K38/39

CPC分类号： A61K38/014 ,  A23K20/147 ,  A23K20/174 ,  A23K20/30 ,  A23L29/284 ,  A23L33/15 ,  A23L33/16 ,  A23L33/17 ,  A23L33/19 ,  A23V2002/00 ,  A61K31/375 ,  A61K33/26 ,  A61K38/39 ,  A61K45/06 ,  A23V2200/318 ,  A23V2200/306 ,  A23V2250/708 ,  A23V2250/1592 ,  A23V2250/5422 ,  A23V2250/54248

摘要： Provided is a nutrient composition for promoting collagen production, which contains vitamin C, an iron preparation, and collagen as active ingredients, promotes collagen production in a living body such as skin or bone, prevents or treats skin aging or bone and joint diseases, and is an iron preparation-containing composition having stability imparted thereto. Also provided are a food or beverage, a feed, and a medicine each containing the nutrient composition incorporated therein.

摘要翻译： 提供了用于促进胶原蛋白生产的营养组合物，其包含维生素C，铁制剂和胶原作为活性成分，促进皮肤或骨骼等活体中的胶原蛋白生成，预防或治疗皮肤老化或骨和关节疾病，以及 是赋予其稳定性的含铁制剂的组合物。 还提供了包含其中并入营养组合物的食品或饮料，饲料和药物。

公开(公告)号：US20100323064A1

公开(公告)日：2010-12-23

申请号：US12526260

申请日：2008-02-12

申请人： Mari Miura ,  Yasuyuki Seto ,  Masayuki Watanabe ,  Toshimitsu Yoshioka

发明人： Mari Miura ,  Yasuyuki Seto ,  Masayuki Watanabe ,  Toshimitsu Yoshioka

IPC分类号： A23C9/12 ,  C01B17/98

CPC分类号： C12N1/04 ,  A23C9/1322 ,  A23L2/44 ,  A23L3/358 ,  A23V2002/00 ,  A23V2200/10 ,  A23V2250/1612

摘要： An object of the present invention is to provide a novel agent for improving the viability of lactic acid bacteria, which has an excellent effect on the improvement of the viability of lactic acid bacteria in the product, has no adverse effect on the flavor of the product and requires less production cost. An agent for improving the viability of lactic acid bacteria characterized by using manganese as an effective ingredient. A manganese-containing material may be used as manganese. Manganese is preferably formulated at 5 μg/100 g or more in the final product.

摘要翻译： 本发明的目的是提供一种用于提高乳酸菌生存力的新型药剂，其对提高产品中乳酸菌的存活力具有优异的效果，对产品的风味没有不利影响 并且需要较少的生产成本。 用于改善以锰为有效成分的乳酸菌的生存力的试剂。 含锰材料可以用作锰。 锰最好在最终产品中配制成5μg/ 100g或更多。

公开(公告)号：US20090253658A1

公开(公告)日：2009-10-08

申请号：US12296222

申请日：2007-04-06

申请人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

发明人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

IPC分类号： A61K31/66 ,  C07F9/06

CPC分类号： A61K35/20 ,  A23L2/52 ,  A23L33/19 ,  A23V2002/00 ,  A61K31/661 ,  A23V2200/332 ,  A23V2250/1844

摘要： To provide a fat accumulation inhibitor and a food or drink for inhibiting fat accumulation, a visceral fat accumulation inhibitor and a food or drink for inhibiting visceral fat accumulation, or an agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.A fat accumulation inhibitor for a fat cell, which comprises a milk-derived phospholipid as an active ingredient, and a food or drink for inhibiting fat accumulation in a fat cell, which comprises a milk-derived phospholipid. A visceral fat accumulation inhibitor comprising a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for inhibiting visceral fat accumulation. An agent for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which comprises a sphingosine-containing phospholipid or a derivative thereof as an active ingredient, and a food or drink for accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood.

摘要翻译： 提供一种脂肪蓄积抑制剂和用于抑制脂肪蓄积的食物或饮料，内脏脂肪蓄积抑制剂和用于抑制内脏脂肪蓄积的食品或饮料，或用于加速和/或抑制血液中脂联素浓度降低的试剂，以及 用于促进血液中脂联素浓度增加和/或抑制降低的食物或饮料。 一种脂肪蓄积抑制剂，其包含乳源性磷脂作为活性成分的脂肪蓄积抑制剂，以及包含乳源性磷脂的脂肪细胞中抑制脂肪蓄积的食品或饮料。 含有鞘氨醇的磷脂或其衍生物作为活性成分的内脏脂肪蓄积抑制剂和抑制内脏脂肪蓄积的食品或饮料。 用于促进增加和/或抑制血液中脂联素浓度降低的药物，其包含含鞘氨醇的磷脂或其衍生物作为活性成分，以及用于加速和/或抑制脂联素浓度降低的食品或饮料 在血中

公开(公告)号：US20120208783A1

公开(公告)日：2012-08-16

申请号：US13347464

申请日：2012-01-10

申请人： Ken Kato ,  Susumu Miura ,  Leo Tanaka ,  Hiroshi Ueno ,  Noriko Ueda ,  Yuko Haruta ,  Toshimitsu Yoshioka

发明人： Ken Kato ,  Susumu Miura ,  Leo Tanaka ,  Hiroshi Ueno ,  Noriko Ueda ,  Yuko Haruta ,  Toshimitsu Yoshioka

IPC分类号： A61K31/688 ,  A61P25/00 ,  C07F9/09

CPC分类号： A61K31/688 ,  A23K20/158 ,  A23K50/40 ,  A23K50/48 ,  A23L2/52 ,  A23L33/10 ,  A23L33/12 ,  A23V2002/00 ,  A61K8/68 ,  A61Q7/00 ,  A61Q19/02 ,  C07F9/10 ,  A23V2250/21 ,  A23V2200/304 ,  A23V2200/32

摘要： It is intended to find novel pharmaceutical use of sphingomyelin and to provide preventive or therapeutic agents for various diseases as well as a food and drink product and feed comprising any of these agents. The present invention provides a pharmaceutical agent which contains sphingomyelin as an active ingredient and is any of the following agents: 1) a sialomucin secretion promoter, 2) an agent for preventing drunken sickness (hangover), 3) an antiallergic agent, 4) an antioxidant, 5) an agent for defending against infection, 6) a hair growth agent, 7) a therapeutic agent for demyelinating disease, 8) an anti-pigmentation agent, 9) an anti-inflammatory agent, and 10) an agent for improving learning ability. The present invention also provides a food and drink product or feed, characterized by comprising the agent. It is preferred that the sphingomyelin should be derived from milk.

摘要翻译： 旨在找到鞘磷脂的新药用途，并提供各种疾病的预防或治疗剂，以及包含任何这些药剂的食品和饮料产品和饲料。 本发明提供含有鞘磷脂作为活性成分的药剂，其为以下药剂：1）唾液酸粘蛋白分泌促进剂，2）防酒醉药（宿醉）3，抗过敏剂4） 抗氧化剂，5）防止感染的药剂，6）毛发生长剂，7）脱髓鞘疾病的治疗剂，8）抗色素沉着剂，9）抗炎剂，和10）改善剂 学习能力 本发明还提供一种食品和饮料产品或饲料，其特征在于包含该试剂。 鞘磷脂优选来源于牛奶。

公开(公告)号：US20120077780A1

公开(公告)日：2012-03-29

申请号：US13240739

申请日：2011-09-22

申请人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

发明人： Reo Tanaka ,  Tomoyuki Isogai ,  Yuko Haruta ,  Susumu Miura ,  Ken Kato ,  Toshimitsu Yoshioka ,  Hiroshi Kawakami ,  Satoshi Higurashi ,  Hiroaki Matsuyama

IPC分类号： A61K31/688 ,  A61K31/685 ,  A61P3/04 ,  A61K31/683

CPC分类号： A61K35/20 ,  A23L2/52 ,  A23L33/19 ,  A23V2002/00 ,  A61K31/661 ,  A23V2200/332 ,  A23V2250/1844

摘要： The present disclosure relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a fat accumulation inhibitor for a fat cell which includes a milk-derived phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of inhibiting a visceral fat accumulation in a subject, which includes administering the visceral fat accumulation inhibitor which includes a sphingosine-containing phospholipid as an active ingredient to the subject. The present disclosure also relates to a method of accelerating increase and/or inhibiting decrease of an adiponectin concentration in blood, which includes administering an agent which includes a sphingosine-containing phospholipid as an active ingredient to the blood. The present disclosure also relates to a method of inhibiting a fat accumulation for a fat cell in a subject, which includes administering a milk-derived phospholipid to a subject.

摘要翻译： 本公开涉及抑制受试者中的脂肪细胞的脂肪蓄积的方法，其包括向受试者施用包含作为有效成分的乳源性磷脂的脂肪细胞的脂肪蓄积抑制剂。 本公开还涉及抑制受试者内脏脂肪蓄积的方法，其包括向受试者施用含有鞘氨醇的磷脂作为活性成分的内脏脂肪蓄积抑制剂。 本公开还涉及一种促进血液中脂联素浓度增加和/或抑制降低的方法，其包括向血液中施用含有鞘氨醇的磷脂作为活性成分的药剂。 本公开还涉及抑制受试者中的脂肪细胞的脂肪蓄积的方法，其包括向受试者施用乳源性磷脂。