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公开(公告)号：US06787308B2
公开(公告)日：2004-09-07
申请号：US09771708
申请日：2001-01-30
Applicant: Shankar Balasubramanian , David Klenerman , David Bentley
Inventor： Shankar Balasubramanian , David Klenerman , David Bentley
IPC: C12Q168
CPC classification number: C12Q1/6837 , B01J19/0046 , B01J2219/00274 , B01J2219/00317 , B01J2219/00497 , B01J2219/00527 , B01J2219/00529 , B01J2219/0054 , B01J2219/00572 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/0061 , B01J2219/00612 , B01J2219/00617 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00702 , B01J2219/00707 , B01J2219/00722 , C12Q2525/301 , C40B40/06 , C40B60/14 , C12Q2521/501 , C12Q2565/507
Abstract: A device comprising an array of molecules immobilised on a solid surface is disclosed, wherein the array has a surface density which allows each molecule to be individually resolved, e.g. by optical microscopy. Therefore, the arrays of the present invention consist of single molecules are more spatially distinct than the arrays of the prior art.
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公开(公告)号：US20050042649A1
公开(公告)日：2005-02-24
申请号：US10864887
申请日：2004-06-09
Applicant: Shankar Balasubramanian , David Bentley
Inventor： Shankar Balasubramanian , David Bentley
IPC: G01N33/53 , B01J20060101 , B01J19/00 , C12M1/00 , C12M1/40 , C12N15/09 , C12Q20060101 , C12Q1/68 , C40B40/06 , C40B60/14 , G01N33/566 , G01N37/00 , C12M1/34
CPC classification number: C40B30/04 , B01J19/0046 , B01J2219/00317 , B01J2219/00497 , B01J2219/00527 , B01J2219/00529 , B01J2219/0054 , B01J2219/00572 , B01J2219/00576 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00608 , B01J2219/00612 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00648 , B01J2219/00659 , B01J2219/00677 , B01J2219/00702 , B01J2219/00707 , B01J2219/00722 , C12Q1/6837 , C12Q2525/301 , C40B40/06 , C40B60/14 , C12Q2565/507
Abstract: A device comprising an array of molecules immobilised on a solid surface is disclosed, wherein the array has a surface density which allows each molecule to be individually resolved, e.g. by optical microscopy. Therefore, the arrays of the present invention consist of single molecules that are more spatially distinct than the arrays of the prior art.
Abstract translation: 公开了一种包含固定在固体表面上的分子阵列的装置，其中阵列具有允许每个分子被单独分辨的表面密度，例如。 通过光学显微镜。 因此，本发明的阵列由比现有技术的阵列更空间不同的单个分子组成。
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3.发明授权Cloud enabled filesystems provided by an agent which interfaces with a file system on a data source device 有权由与数据源设备上的文件系统接口的代理提供的启用云的文件系统公开(公告)号：US09135116B1
公开(公告)日：2015-09-15
申请号：US13248389
申请日：2011-09-29
Applicant: Shankar Balasubramanian , Anil Degwekar , Srinivasan Ramachandran , Anand Raj , Deepak Visweswaraiah
Inventor： Shankar Balasubramanian , Anil Degwekar , Srinivasan Ramachandran , Anand Raj , Deepak Visweswaraiah
CPC classification number: G06F11/1435 , G06F3/061 , G06F3/0635 , G06F3/0647 , G06F3/067 , G06F11/1448 , G06F17/30091
Abstract: Information is managed by receiving at a data source device, from an application running on a data source device, an instruction associated with a file system object. It is determined at the data source device if the instruction is able to be satisfied by a file system running on the data source device. If it is determined that the instruction is not able to be satisfied by the file system, the instruction is performed without the services of the file system; the application is unaware that the file system object is managed by an entity other than the file system running on the data source device.
Abstract translation: 通过在数据源设备上从在数据源设备上运行的应用接收与文件系统对象相关联的指令来管理信息。 在数据源设备中确定是否能够由在数据源设备上运行的文件系统来满足该指令。 如果确定文件系统不能满足该指令，则在没有文件系统的服务的情况下执行指令; 应用程序不知道文件系统对象由除数据源设备上运行的文件系统之外的实体管理。
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公开(公告)号：US20120202196A1
公开(公告)日：2012-08-09
申请号：US13432989
申请日：2012-03-28
Applicant: Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
Inventor： Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
CPC classification number: C12Q1/6869 , C07H19/10 , C07H19/20 , C07H21/00 , C12P19/34 , C12Q1/6806 , C12Q1/6818 , C12Q1/6823 , C12Q1/6834 , C12Q1/6874 , C12Q1/6876 , C12Q2525/186
Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
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公开(公告)号：US20120184457A1
公开(公告)日：2012-07-19
申请号：US13389159
申请日：2010-08-06
Applicant: Eric Miska , Nicolas Lehrbach , Javier Armisen-Garrido , Shankar Balasubramanian
Inventor： Eric Miska , Nicolas Lehrbach , Javier Armisen-Garrido , Shankar Balasubramanian
CPC classification number: C12Q1/485 , G01N33/573 , G01N2333/9125 , G01N2500/02
Abstract: Provided is a method of identifying a compound which modulates miRNA activity comprising (i) determining the ability of a test compound to alter the polyuridylation activity of a ZCCHC polypeptide wherein a test compound which alters the polyuridylation activity is useful in modulating miRNA activity; or (ii) determining the ability of a test compound to alter the binding of a ZCCHC polypeptide to a LIN28 polypeptide, wherein a test compound which alters said binding may be useful in modulating miRNA activity; or (iii) determining the ability of a test compound to bind to a ZCCHC polypeptide, wherein a test compound which binds to the ZCCHC polypeptide may be useful in modulating miRNA activity.
Abstract translation: 提供了鉴定调节miRNA活性的化合物的方法，其包括（i）测定测试化合物改变ZCCHC多肽的多聚尿苷酸化活性的能力，其中改变多聚尿苷酸化活性的测试化合物可用于调节miRNA活性; 或（ii）测定测试化合物改变ZCCHC多肽与LIN28多肽的结合的能力，其中改变所述结合的测试化合物可用于调节miRNA活性; 或（iii）测定测试化合物结合ZCCHC多肽的能力，其中与ZCCHC多肽结合的测试化合物可用于调节miRNA活性。
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Patent Agency Ranking
公开(公告)号：US08148064B2
公开(公告)日：2012-04-03
申请号：US12804296
申请日：2010-07-19
Applicant: Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
Inventor： Shankar Balasubramanian , Colin Barnes , Xiaohai Liu , John Milton
CPC classification number: C12Q1/6869 , C07H19/10 , C07H19/20 , C07H21/00 , C12P19/34 , C12Q1/6806 , C12Q1/6818 , C12Q1/6823 , C12Q1/6834 , C12Q1/6874 , C12Q1/6876 , C12Q2525/186
Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
Abstract translation: 公开了通过可切割连接基团与可检测标记物连接的核苷和核苷酸。
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7.发明申请Preparation of Precisely Controlled Thin Film Nanocomposite of Carbon Nanotubes and Biomaterials 审中-公开制备碳纳米管和生物材料的精确控制薄膜纳米复合材料公开(公告)号：US20100028960A1
公开(公告)日：2010-02-04
申请号：US12261892
申请日：2008-10-30
Applicant: Virginia A. Davis , Aleksandr L. Simonian , Dhriti Nepal , Shankar Balasubramanian
Inventor： Virginia A. Davis , Aleksandr L. Simonian , Dhriti Nepal , Shankar Balasubramanian
CPC classification number: B82Y5/00 , A01N37/46 , A01N57/16 , Y10T428/265 , A01N25/10 , A01N25/34 , A01N2300/00
Abstract: Disclosed are nanocomposite materials comprising multiple layers of biomolecules bound to aligned carbon nanotubes. The thickness of each of the layers may be precisely controlled using a layer-by-layer assembly technique.
Abstract translation: 公开了纳米复合材料，其包含结合到对准的碳纳米管的多层生物分子。 可以使用逐层组装技术来精确地控制每个层的厚度。
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公开(公告)号：US20060188901A1
公开(公告)日：2006-08-24
申请号：US11301578
申请日：2005-12-13
Applicant: Colin Barnes , Shankar Balasubramanian , Xiaohai Liu , Harold Swerdlow , John Milton
Inventor： Colin Barnes , Shankar Balasubramanian , Xiaohai Liu , Harold Swerdlow , John Milton
CPC classification number: C07H19/06 , C07H19/10 , C07H19/16 , C07H19/20 , C07H21/00 , C12Q1/6869 , C12Q2525/186 , C12Q2535/113 , C12Q2525/197
Abstract: Nucleosides and nucleotides are disclosed that are linked to detectable labels via a cleavable linker group.
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公开(公告)号：US20060166864A1
公开(公告)日：2006-07-27
申请号：US11398130
申请日：2006-04-04
Applicant: Yen Choo , Mark Isalan , Sachin Patel , Shankar Balasubramanian , Xiohai Liu
Inventor： Yen Choo , Mark Isalan , Sachin Patel , Shankar Balasubramanian , Xiohai Liu
CPC classification number: A61K38/1709 , C07K14/4702 , C07K2319/00
Abstract: Disclosed herein are engineered zinc finger proteins which bind to telomeric structures; methods for their design, synthesis and use; and cells comprising a telomere-binding zinc finger protein. Methods for modulating telomerase activity using telomere-binding zinc finger proteins are also provided.
Abstract translation: 本文公开了结合端粒结构的工程化锌指蛋白; 其设计，综合和使用方法; 和包含端粒结合锌指蛋白的细胞。 还提供了使用端粒结合锌指蛋白调节端粒酶活性的方法。
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公开(公告)号：US20060005233A1
公开(公告)日：2006-01-05
申请号：US11198834
申请日：2005-08-05
Applicant: James Kleinsteiber , Richard Hammons , Hung Nguyen , Shankar Balasubramanian , Vidya Renganararayanan
Inventor： James Kleinsteiber , Richard Hammons , Hung Nguyen , Shankar Balasubramanian , Vidya Renganararayanan
CPC classification number: H04L63/08 , H04L63/0428 , H04L63/0823 , H04L63/0869 , H04L63/104 , H04L63/20 , H04L2463/102
Abstract: A method and apparatus for securing networks, focusing on application in Fibre Channel networks. A combination of unique security techniques are combined to provide overall network security. Responsibility for security in the network is assigned to one or more designated entities. The designated entities deploy management information throughout the network to enhance security by modifying the capabilities and operational permissions of the devices participating in the network. For example, through network control: logical management access or physical I/O access may be limited on a per device or per I/O basis; and all devices and ports in the network operate only with other approved devices and ports. These designated entities can better manage network security by exploiting a unique link authentication system as well as a unique push-model secure distributed time service. The link authentication involves a multi-phase nonce exchange exploiting various derivations of the nonce and other information such as hashes and encryptions. The push-model secure time distribution departs from the traditional Fibre Channel pull mode time distribution and provides for secure and reliable distributed time so that various security attacks may be defeated.
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