公开(公告)号：US20190168222A1

公开(公告)日：2019-06-06

申请号：US16325453

申请日：2017-07-21

Applicant: Sony Corporation

Inventor： Kensuke Kojima ,  Shin Masuhara ,  Toshio Watanabe

IPC: B01L3/00 ,  B81B1/00 ,  G01N15/10

Abstract: Provided is a single-particle capturing apparatus in which one particle can be captured in one recess portion (16) while preventing another particle from being accumulated on a captured particle.A single-particle capturing apparatus including: a flow channel (12) on a substrate (11), a wave structure with a mountain portion (13) and a valley portion (14) on the flow channel (12), and a recess portion (16) at a top portion (15) of the mountain portion (13), the recess portion (16) including a draw-in passage (17).

公开(公告)号：US20140038280A1

公开(公告)日：2014-02-06

申请号：US13953914

申请日：2013-07-30

Applicant: Sony Corporation

Inventor： Masaki Sato ,  Tomohiko Nakamura ,  Kenzo Machida ,  Toshio Watanabe ,  Yoshiaki Kato ,  Michihiro Ohnishi

IPC: C12Q1/68

CPC classification number: C12Q1/6844 ,  B01L3/502761 ,  B01L2200/0668 ,  B01L2200/16 ,  B01L2300/046 ,  B01L2300/0654 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/043 ,  B01L2400/049 ,  B01L2400/086

Abstract: There is provided a microchip for a nucleic acid amplification reaction including a reagent accommodation region including a solid-phase reagent and a particle, the solid-phase reagent containing a substance necessary for a nucleic acid amplification reaction.

Abstract translation: 提供了用于核酸扩增反应的微芯片，其包括包含固相试剂和颗粒的试剂容纳区域，所述固相试剂含有核酸扩增反应所必需的物质。

公开(公告)号：US20150251184A1

公开(公告)日：2015-09-10

申请号：US14417703

申请日：2013-05-27

Applicant: Sony Corporation

Inventor： Toshio Watanabe ,  Masayoshi Akita ,  Takanori Anaguchi

IPC: B01L7/00 ,  C12Q1/68

CPC classification number: B01L7/5255 ,  B01L7/52 ,  B01L2200/04 ,  B01L2200/12 ,  B01L2200/14 ,  B01L2300/043 ,  B01L2300/0609 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/123 ,  B01L2300/1805 ,  B01L2300/1822 ,  B01L2300/1833 ,  C12Q1/6846 ,  G01N21/6452 ,  G01N35/00029 ,  G01N2035/00158 ,  G01N2035/00306 ,  G01N2035/00316 ,  G01N2035/00376 ,  G01N2035/1034 ,  Y10T29/49998

Abstract: There is provided a nucleic acid analysis apparatus including a heating unit configured to apply heat by contacting a microchip, and a chip holding unit configured to change a position between a first holding position that holds the microchip in midair and a second holding position that holds the microchip in contact with the heating unit.

Abstract translation: 提供了一种核酸分析装置，其包括：加热单元，其被配置为通过接触微芯片来加热;以及芯片保持单元，其构造成改变在空中保持微芯片的第一保持位置与保持微芯片的第二保持位置之间的位置 微芯片与加热单元接触。

公开(公告)号：US20130153424A1

公开(公告)日：2013-06-20

申请号：US13709770

申请日：2012-12-10

Applicant: Sony Corporation

Inventor： Masahiro Matsumoto ,  Michihiro Ohnishi ,  Yoshiaki Kato ,  Toshio Watanabe

IPC: G01N27/447

CPC classification number: G01N27/44743 ,  B01L3/502707 ,  B01L2200/0605 ,  B01L2200/141 ,  B01L2300/044 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0887 ,  B01L2300/123 ,  B01L2400/049

Abstract: Provided is a microchip, including independently an introduction area inside having a pressure negative to atmospheric pressure and into which a liquid is injected by puncturing, and a degassing area inside having a pressure negative to atmospheric pressure for degassing a cavity of a hollow tube that punctures the introduction area for injecting the liquid.

Abstract translation: 提供一种微芯片，其独立地包括内部具有负压至大气压的引入区域，并且通过穿刺将液体注入到该引入区域中，以及内部具有负压至大气压力的脱气区域，用于对穿孔的中空管的空腔进行脱气 用于注射液体的引入区域。

公开(公告)号：US10956547B2

公开(公告)日：2021-03-23

申请号：US16151878

申请日：2018-10-04

Applicant: SONY CORPORATION

Inventor： Kenji Yamamoto ,  Hideo Sato ,  Isao Ichimura ,  Toshio Watanabe ,  Shinichi Kai ,  Junji Kajihara ,  Kengo Hayasaka

IPC: G06F21/32 ,  G06K9/00 ,  G06K9/20

Abstract: A biometrics authentication system having a small and simple configuration and being capable of implementing both of biometrics authentication and position detection is provided. A biometrics authentication system includes a light source emitting light to an object, a microlens array section condensing light from the object, a light-sensing device obtaining light detection data of the object on the basis of the light condensed by the microlens array section, a position detection section detecting the position of the object on the basis of the light detection data obtained in the light-sensing device, and an authentication section, in the case where the object is a living body, performing authentication of the living body on the basis of the light detection data obtained in the light-sensing device.

公开(公告)号：US10919035B2

公开(公告)日：2021-02-16

申请号：US15554443

申请日：2016-02-24

Applicant: Sony Corporation

Inventor： Shin Masuhara ,  Yoshiaki Kato ,  Ryousuke Minami ,  Toshio Watanabe

IPC: G01N21/05 ,  B01L3/00 ,  G01N21/03

Abstract: According to some aspects, a microfluidic device is provided, comprising a sample holding chamber; and at least one flow path connected to the sample holding chamber configured to supply liquid into the sample holding chamber, wherein the sample holding chamber includes a first inner surface; and a light irradiation region intersecting the first inner surface and configured to receive light from outside of the sample holding chamber to irradiate liquid inside the sample holding chamber, wherein the first inner surface includes at least one recess shaped so as to contain gas bubbles present within the liquid, and wherein the at least one recess is located outside of the light irradiation region.

公开(公告)号：US20150004676A1

公开(公告)日：2015-01-01

申请号：US14375315

申请日：2013-01-30

Applicant: Sony Corporation

Inventor： Masahiro Matsumoto ,  Michihiro Ohnishi ,  Yoshiaki Kato ,  Toshio Watanabe

IPC: G01N1/28

CPC classification number: G01N1/28 ,  B01L3/50273 ,  B01L2300/0627 ,  B01L2400/049

Abstract: A microchip is provided and configured to contain a sample solution for analysis. The microchip including a channel that is maintained at a pressure level less than atmospheric pressure so as to allow flow of the sample solution thru the channel; and a pressure indication section configured to detect a change in the pressure level. A microchip apparatus and a method of manufacturing a microchip are also provided.

Abstract translation: 微芯片被提供并配置成容纳用于分析的样品溶液。 微芯片包括保持在低于大气压力的压力水平的通道，以允许样品溶液流过通道; 以及构造成检测压力水平的变化的压力指示部。 还提供了微芯片装置和微芯片的制造方法。

公开(公告)号：US20140241955A1

公开(公告)日：2014-08-28

申请号：US14348771

申请日：2012-10-04

Applicant: Sony Corporation

Inventor： Toshio Watanabe ,  Kensuke Kojima ,  Yuji Segawa ,  Hidetoshi Watanabe ,  Yoshiaki Kato

IPC: B01L3/00 ,  G01N35/10

CPC classification number: G01N35/10 ,  B01L3/021 ,  B01L3/022 ,  B01L3/5027 ,  B01L2200/027

Abstract: A liquid injecting jig is provided. The liquid injecting jig includes a jig configuration including a plurality of parts adapted to be in cooperative engagement so as to position a channel within the jig configuration, wherein the jig configuration is adapted to fit an opening through which the channel is adapted to be received so as to expose the channel from the jig configuration. A jig set, a microchip case, and a microchip set are also provided.

Abstract translation: 提供液体注入夹具。 液体注入夹具包括夹具构造，其包括适于协调接合的多个部件，以便将夹具配置中的通道定位，其中夹具构造适于安装通道适于接收的开口， 以使通道从夹具配置中露出。 还提供了夹具组，微芯片壳和微芯片组。

公开(公告)号：US20200330989A1

公开(公告)日：2020-10-22

申请号：US16643234

申请日：2018-09-06

Applicant: Sony Corporation

Inventor： Shin Masuhara ,  Kensuke Kojima ,  Hiroyuki Hosokawa ,  Yoshiaki Kato ,  Marcaurele Brun ,  Toshio Watanabe

IPC: B01L3/00 ,  G01N15/14

Abstract: There is provided a microfluidic device for capturing particles comprising a particle capturing chamber (100) including at least: a particle capturing unit (101) including one of at least one well (106) or at least one through hole (108); and a particle capturing channel unit (102) used for capturing a particle in the well or with the through hole, in which the particle is captured in the well or with the through hole by being sucked, via the particle capturing channel unit, in a direction opposite to a direction (114) on which the particle settles. Such a configuration has for result that the particles that are not captured in the well or with the through hole are prevented from staying in the vicinity of the well or the through hole of the particle capturing unit when suction is stopped.

公开(公告)号：US20180065119A1

公开(公告)日：2018-03-08

申请号：US15554443

申请日：2016-02-24

Applicant: Sony Corporation

Inventor： Shin Masuhara ,  Yoshiaki Kato ,  Ryousuke Minami ,  Toshio Watanabe

IPC: B01L3/00 ,  G01N21/05

CPC classification number: B01L3/502707 ,  B01L3/502715 ,  B01L3/502723 ,  B01L2200/0684 ,  B01L2200/16 ,  B01L2300/0816 ,  B01L2300/0864 ,  G01N21/05 ,  G01N2021/0378 ,  G01N2021/054

Abstract: According to some aspects, a microfluidic device is provided, comprising a sample holding chamber; and at least one flow path connected to the sample holding chamber configured to supply liquid into the sample holding chamber, wherein the sample holding chamber includes a first inner surface; and a light irradiation region intersecting the first inner surface and configured to receive light from outside of the sample holding chamber to irradiate liquid inside the sample holding chamber, wherein the first inner surface includes at least one recess shaped so as to contain gas bubbles present within the liquid, and wherein the at least one recess is located outside of the light irradiation region.