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    Orbital dissection cannula and method
    1.
    发明授权
    Orbital dissection cannula and method 失效
    轨道解剖套管及方法

    公开(公告)号：US5984937A

    公开(公告)日：1999-11-16

    申请号：US828578

    申请日：1997-03-31

    申请人： Stephen A. Morse ,  Peter L. Callas ,  Geoffrey A. Orth ,  Andrew G. C. Frazier ,  Albert K. Chin

    发明人： Stephen A. Morse ,  Peter L. Callas ,  Geoffrey A. Orth ,  Andrew G. C. Frazier ,  Albert K. Chin

    IPC分类号： A61B17/00 ,  A61B17/32 ,  A61B17/34

    CPC分类号： A61B17/00008 ,  A61B2017/00969 ,  A61B2017/320044 ,  A61B2017/3445

    摘要： A cannula and method provide manually manipulable orientation of a dissection probe carried eccentricity on the cannula for rotational and translational positioning relative to the field of view of an endoscope at a distal end of the cannula. Rotation of the cannula at fixed axial position relative to the endoscope, and rotational and translational positioning of the dissection probe relative to the distal end of the cannula provide wide-area access within the surgical site for bluntly dissecting connective tissue surrounding a vessel of interest being harvested.

    摘要翻译： 插管和方法提供了在套管上承载偏心的解剖探针的手动可操纵取向，用于相对于插管的远端处的内窥镜的视场进行旋转和平移定位。 插管在相对于内窥镜的固定的轴向位置的旋转以及解剖探针相对于套管的远端的旋转和平移定位提供了在手术部位内的广泛进入，用于直接解剖围绕感兴趣的血管的结缔组织 收获。

    Removal of tissue from within a body cavity
    2.
    发明授权
    Removal of tissue from within a body cavity 失效
    从体腔内去除组织

    公开(公告)号：US5336237A

    公开(公告)日：1994-08-09

    申请号：US111984

    申请日：1993-08-25

    申请人： Albert K. Chin ,  John McIntyre ,  Stephen A. Morse

    发明人： Albert K. Chin ,  John McIntyre ,  Stephen A. Morse

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B17/32

    CPC分类号： A61B17/3207 ,  A61B17/00234 ,  A61B17/320016 ,  A61B2017/00287 ,  A61B2017/00685 ,  A61B2017/320775

    摘要： A method and system for removing an organ or piece of tissue severed from its supporting tissue within a patient's body cavity, such as the abdominal cavity, which includes an elongated expandable tubular member with a sealed interior. In one preferred embodiment for morcellation, means are provided within the sealed interior to tear or cut off tissue fragments from the organ or tissue which are small enough to pass out of the patient's body cavity through an inner lumen of an exit trocar sheath disposed within the patient and in communication with the body cavity. The organ or piece of tissue is placed within an inner lumen defined by the sealed interior through an opening provided in a leading portion of the elongated expandable tubular member. The organ or piece of tissue is fragmented into smaller pieces which are withdrawn from the patient's body cavity by the passage of the morcellation system through the inner lumen of the exit trocar sheath. In one embodiment of the morcellation system, one or more elongated cutting strips are disposed within the inner lumen defined by the sealed interior and secured to the lining to cut or tear the tissue into small fragments. In another embodiment of the invention one or more elongated helical ribbons are provided to cut or tear the tissue into small fragments.

    摘要翻译： 一种用于去除患者体腔（例如腹腔）内的其支撑组织切除的器官或系统的方法和系统，其包括具有密封内部的细长可扩张管状构件。 在一个优选的实施方式中，在密封的内部设置有用于撕开或切断器官或组织的组织碎片的装置，该器官或组织足够小以通过设置在内部的出口套管针护套的内腔 患者和身体的沟通。 器官或组织被放置在由密封内部限定的内腔内，通过设置在细长可扩张管状构件的引导部分中的开口。 器官或组织碎片被分割成较小的片，其通过穿过出口套管针鞘的内腔而从患者体腔抽出。 在切割系统的一个实施例中，一个或多个细长切割条设置在由内部限定的内腔内并固定到衬里上以将组织切割或撕裂成小碎片。 在本发明的另一个实施例中，提供一个或多个细长螺旋带以将组织切割或撕裂成小碎片。

    Device having an electroformed pleated region and method of its manufacture
    3.
    发明授权
    Device having an electroformed pleated region and method of its manufacture 有权
    具有电铸褶皱区域的装置及其制造方法

    公开(公告)号：US09572953B2

    公开(公告)日：2017-02-21

    申请号：US13194580

    申请日：2011-07-29

    申请人： John W. Sliwa ,  Stephen A. Morse

    发明人： John W. Sliwa ,  Stephen A. Morse

    IPC分类号： A61B18/14 ,  A61M25/00 ,  A61M25/01 ,  C25D1/00

    CPC分类号： A61M25/001 ,  A61B18/1492 ,  A61M25/0074 ,  A61M25/008 ,  A61M25/0133 ,  A61M25/0141 ,  A61M25/0147 ,  A61M25/0155 ,  A61M25/0158 ,  B23K26/389 ,  B23K2101/08 ,  B23K2103/08 ,  C23C28/021 ,  C23C28/023 ,  C25D1/00 ,  C25D1/02 ,  C25D1/20 ,  C25D3/48 ,  C25D3/50

    摘要： A deflectable, flexible device includes an elongate body, a convoluted tip portion at a distal end of the elongate body, and a lumen to receive one or more wires. The convoluted tip portion includes an electroformed pleated region which is formed by electrodepositing a metal on a mandrel having a pleated region. The convoluted tip portion may be hermetically sealed to permit repeated sterilization. The electroformed pleated region may include one or more fluid emission orifices. The convoluted tip portion extends or bends in response to fluid pressure manipulation, contact with tissue, manipulation with an internal spring or wire, or by a user pushing, pulling, or twisting the catheter directly or via an introducer sheath or the like. The convoluted tip portion may further include an RF ablation element or other energy-driven technique to create continuous linear lesions or a sensing element.

    摘要翻译： 可偏转的柔性装置包括细长主体，在细长主体的远端处的回旋顶端部分和用于接收一根或多根线的内腔。 卷曲的末端部分包括电铸褶皱区域，其通过将金属电沉积在具有褶皱区域的心轴上而形成。 卷曲的尖端部分可以被气密地密封以允许反复的灭菌。 电铸褶皱区域可以包括一个或多个流体排出孔。 旋转的尖端部分响应于流体压力操纵，与组织的接触，用内部弹簧或线的操作，或者由使用者直接地或经由导引器鞘或类似物推动，拉动或扭转导管而延伸或弯曲。 旋回的尖端部分还可以包括RF消融元件或其他能量驱动技术，以产生连续的线性损伤或感测元件。

    Apparatus and method for tissue ablation with near-field cooling
    4.
    发明授权
    Apparatus and method for tissue ablation with near-field cooling 有权
    近场冷却组织消融的装置和方法

    公开(公告)号：US09108037B2

    公开(公告)日：2015-08-18

    申请号：US12400198

    申请日：2009-03-09

    申请人： John W. Sliwa ,  Stephen A. Morse ,  John P. Goetz

    发明人： John W. Sliwa ,  Stephen A. Morse ,  John P. Goetz

    IPC分类号： A61B18/04 ,  A61N7/02 ,  A61B17/225 ,  A61B17/00 ,  A61B18/00

    CPC分类号： A61N7/02 ,  A61B17/2251 ,  A61B2017/00084 ,  A61B2018/00011

    摘要： A tissue ablation system facilitates lesioning deep tissue while preventing damage to superficial tissue and includes a probe having a distal end portion, at least one transducer carried on the distal end portion, and at least one acoustically transparent heat removal element thermally coupled to a target tissue within the beam path of the transducer. The transducer delivers acoustic energy to the tissue through the heat removal element in order to ablate the tissue; the heat removal element removes sufficient thermal energy from the tissue volume to prevent thermal necrosis in superficial tissue. The heat removal element may be a heat sink or a convective element. An optional temperature sensor provides advisory data to a practitioner and/or is coupled to a feedback control system operable to control delivery of acoustic energy to the tissue and/or a rate of thermal energy removal therefrom.

    摘要翻译： 组织消融系统便于损伤深部组织，同时防止对表面组织的损伤，并且包括具有远端部分的探针，至少一个在远端部分上承载的传感器，以及至少一个热耦合到靶组织的声透明散热元件 在传感器的光束路径内。 换能器通过散热元件向组织传递声能以便烧蚀组织; 除热元件从组织体积去除足够的热能以防止表面组织中的热坏死。 散热元件可以是散热器或对流元件。 可选的温度传感器向从业者提供咨询数据和/或耦合到可操作以控制向组织传递声能的反馈控制系统和/或从其中去除热能的速率。

    Apparatus and Method for Tissue Ablation with Near-Field Cooling
    5.
    发明申请
    Apparatus and Method for Tissue Ablation with Near-Field Cooling 有权
    近场冷却组织消融的装置和方法

    公开(公告)号：US20100228162A1

    公开(公告)日：2010-09-09

    申请号：US12400198

    申请日：2009-03-09

    申请人： John W. Sliwa ,  Stephen A. Morse ,  John P. Goetz

    发明人： John W. Sliwa ,  Stephen A. Morse ,  John P. Goetz

    IPC分类号： A61N7/00

    CPC分类号： A61N7/02 ,  A61B17/2251 ,  A61B2017/00084 ,  A61B2018/00011

    摘要： A tissue ablation system facilitates lesioning deep tissue while preventing damage to superficial tissue and includes a probe having a distal end portion, at least one transducer carried on the distal end portion, and at least one acoustically transparent heat removal element thermally coupled to a target tissue within the beam path of the transducer. The transducer delivers acoustic energy to the tissue through the heat removal element in order to ablate the tissue; the heat removal element removes sufficient thermal energy from the tissue volume to prevent thermal necrosis in superficial tissue. The heat removal element may be a heat sink or a convective element. An optional temperature sensor provides advisory data to a practitioner and/or is coupled to a feedback control system operable to control delivery of acoustic energy to the tissue and/or a rate of thermal energy removal therefrom.

    摘要翻译： 组织消融系统便于损伤深部组织，同时防止对表面组织的损伤，并且包括具有远端部分的探针，至少一个在远端部分上承载的传感器，以及至少一个热耦合到靶组织的声透明散热元件 在传感器的光束路径内。 换能器通过散热元件向组织传递声能以便烧蚀组织; 除热元件从组织体积去除足够的热能以防止表面组织中的热坏死。 散热元件可以是散热器或对流元件。 可选的温度传感器向从业者提供咨询数据和/或耦合到可操作以控制向组织传递声能的反馈控制系统和/或从其中去除热能的速率。

    Delivery of intracorporeal probes
    8.
    发明授权
    Delivery of intracorporeal probes 失效
    交付体内探针

    公开(公告)号：US5549601A

    公开(公告)日：1996-08-27

    申请号：US321398

    申请日：1994-10-11

    申请人： John McIntyre ,  Peter S. Brown ,  Stephen A. Morse

    发明人： John McIntyre ,  Peter S. Brown ,  Stephen A. Morse

    IPC分类号： A61B17/00 ,  A61B17/22 ,  A61B18/24 ,  A61B19/00 ,  A61B17/36

    CPC分类号： A61B18/24 ,  A61B17/320758 ,  A61B2017/00274 ,  A61B2017/0084 ,  A61B2017/22072 ,  A61B2017/22077 ,  A61B2017/22078 ,  A61B2018/00547 ,  A61B90/361

    摘要： A system for delivering a probe into a body part to perform a therapeutic or diagnostic procedure therein which includes an elongated probe device which is disposed within a protective sheath and which has a rotary drive unit connected to its proximal extremity to rotate the probe about its longitudinal axis, preferably at a rate above 50 rpms while applying axial pressure thereto to cause the distal end of the probe to penetrate through the patient's tissue to a desired location in the body part where the procedure is to occur. In a presently preferred embodiment, the probe is an optical fiber which is delivered into a male patient's prostate gland through the patient's prostatic urethral wall. The optical fiber is optically connected to a source for laser energy (815 nm) which is emitted from the distal end of the optical fiber to ablate prostatic tissue surrounding the distal end. A sheath is disposed about the optical fiber to support the shaft thereof and to minimize damage to the working channel of a cystoscope through which the device is usually advanced to reach the desired location within the patient's prostatic urethra.

    摘要翻译： 一种用于将探针输送到身体部分以执行其中的治疗或诊断程序的系统，其包括设置在保护护套内的细长探针装置，并且具有连接到其近端的旋转驱动单元，以围绕其纵向 轴，优选地以高于50rpms的速率，同时向其施加轴向压力，以使探针的远端穿过患者组织穿过要进行手术的身体部位中的期望位置。 在目前优选的实施方案中，探针是通过患者的前列腺尿道壁输送到男性患者的前列腺中的光纤。 光纤被光学连接到从光纤的远端发射的激光能量源（815nm），以消融围绕远端的前列腺组织。 护套设置在光纤周围以支撑其轴并且最小化对膀胱镜的工作通道的损伤，通过该护套通常将器械推进到达患者前列腺尿道内的期望位置。

    Apparatus and Methods for Acoustic Monitoring of Ablation Procedures
    10.
    发明申请
    Apparatus and Methods for Acoustic Monitoring of Ablation Procedures 审中-公开
    消融程序声学监测仪器和方法

    公开(公告)号：US20100168572A1

    公开(公告)日：2010-07-01

    申请号：US12636837

    申请日：2009-12-14

    申请人： John W. Sliwa ,  Zhenyi Ma ,  John P. Goetz ,  Stephen A. Morse

    发明人： John W. Sliwa ,  Zhenyi Ma ,  John P. Goetz ,  Stephen A. Morse

    IPC分类号： A61B8/00 ,  A61B18/18

    CPC分类号： A61B18/1492 ,  A61B7/00 ,  A61B8/0833 ,  A61B8/0858 ,  A61B8/0883 ,  A61B8/12 ,  A61B8/4472 ,  A61B8/4483 ,  A61B8/462 ,  A61B8/463 ,  A61B8/5215 ,  A61B2017/00106 ,  A61B2018/00577 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/1861 ,  A61B2090/065

    摘要： A system for ablating tissue includes a catheter having an elongate body, with at least one ablation element (e.g., RF electrode) and at least one acoustic transducer located within the body's tip region. The transducer receives acoustic signals from proximate the tip region. The system also includes a monitoring unit coupled to the transducer to interpret the received acoustic signals as data regarding at least one therapeutic parameter (e.g., pre-pop detection, lesion making progress, tissue interface detection, tissue contact force, tissue contact establishment, bubble spatial distribution, bubble depth, bubble size, bubble size distribution, tissue interface distance, tissue interface position, tissue attenuation, tissue thickness, lesion spectral fingerprint). The monitoring unit is operable to provide feedback to a practitioner, such as graphical, audible, and/or haptic output of sensed data, and may also be operable to control operation of the at least one ablation element in response thereto.

    摘要翻译： 用于烧蚀组织的系统包括具有细长主体的导管，其具有至少一个消融元件（例如，RF电极）和位于身体尖端区域内的至少一个声学换能器。 换能器从尖端区域附近接收声信号。 该系统还包括耦合到换能器的监测单元，以将接收到的声学信号解释为关于至少一个治疗参数的数据（例如，预弹头检测，病变进展，组织界面检测，组织接触力，组织接触建立，气泡 空间分布，气泡深度，气泡尺寸，气泡尺寸分布，组织界面距离，组织界面位置，组织衰减，组织厚度，病变光谱指纹图）。 监测单元可操作以向实践者提供反馈，例如感测数据的图形，可听和/或触觉输出，并且还可操作以响应于此控制至少一个消融元件的操作。