公开(公告)号：US20200033068A1

公开(公告)日：2020-01-30

申请号：US16521019

申请日：2019-07-24

申请人： Takeshi Endoh ,  Takashi Tanaka ,  Akihiko Moki ,  Atsuo Hirai

发明人： Takeshi Endoh ,  Takashi Tanaka ,  Akihiko Moki ,  Atsuo Hirai

IPC分类号： F28D15/04 ,  H05K7/20

摘要： A wick includes a porous body. The porous body includes a plurality of bubbles, a plurality of composite cells, and a plurality of communication holes. The plurality of bubbles has sizes in a range from 0.1 μm to 50 μm, both inclusive, in a cross section obtained when the porous body is cut. The plurality of composite cells is formed by spherical bubbles partially overlapping each other. Bubbles of pore sizes from 5 μm to 10 μm, both inclusive, are most present among the plurality of composite cells. The plurality of communication holes of 5 μm or smaller is between the plurality of bubbles.

公开(公告)号：US20190390918A1

公开(公告)日：2019-12-26

申请号：US16444212

申请日：2019-06-18

申请人： Tomoyasu Hirasawa ,  Kiyotada Katoh ,  Takeshi Endoh ,  Takashi Tanaka ,  Toshihiko Baba ,  Keisuke Ikeda ,  Hiroki Yamasaki

发明人： Tomoyasu Hirasawa ,  Kiyotada Katoh ,  Takeshi Endoh ,  Takashi Tanaka ,  Toshihiko Baba ,  Keisuke Ikeda ,  Hiroki Yamasaki

IPC分类号： F28D15/02 ,  H05K7/20

摘要： A disclosed loop heat pipe includes an evaporator configured to absorb heat from outside by a wall to evaporate a working fluid from a liquid phase gas phase; a condenser configured to condense a gas phase working fluid introduced from the evaporator into a liquid phase; an elastic wick configured to contact an inner wall of the evaporator by an elastic force from the elastic wick; and a wick deformation member configured to deform the elastic wick increase a contact pressure of the elastic wick against the inner wall of the evaporator.

公开(公告)号：US09212130B2

公开(公告)日：2015-12-15

申请号：US13816085

申请日：2011-08-09

申请人： Hiroyuki Kai ,  Takeshi Endoh ,  Sae Jikihara ,  Tohru Horiguchi

发明人： Hiroyuki Kai ,  Takeshi Endoh ,  Sae Jikihara ,  Tohru Horiguchi

IPC分类号： A61K31/505 ,  A61K31/497 ,  A61K31/44 ,  A61K31/135 ,  A61K31/425 ,  C07C233/75 ,  C07C217/84 ,  C07C217/80 ,  C07D401/14 ,  C07D239/84 ,  C07D211/72 ,  C07D237/04 ,  C07C217/92 ,  C07D213/74 ,  C07D213/80 ,  C07D213/82 ,  C07D215/22 ,  C07D217/24 ,  C07D231/38 ,  C07D233/96 ,  C07D235/30 ,  C07D237/32 ,  C07D239/42 ,  C07D239/47 ,  C07D239/54 ,  C07D239/95 ,  C07D239/96 ,  C07D241/20 ,  C07D255/02 ,  C07D261/12 ,  C07D263/32 ,  C07D263/34 ,  C07D263/48 ,  C07D265/10 ,  C07D265/26 ,  C07D265/36 ,  C07D277/20 ,  C07D277/34 ,  C07D277/38 ,  C07D401/12 ,  C07D405/12 ,  C07D405/14 ,  C07D417/12 ,  C07D417/14 ,  C07D277/28 ,  C07D405/06 ,  C07D409/06 ,  C07D409/12 ,  C07D413/12 ,  C07D407/06 ,  C07C233/25 ,  C07D215/56 ,  C07D217/22 ,  C07D233/88 ,  C07D237/20 ,  C07D239/48 ,  C07D239/545 ,  C07D239/557 ,  C07D239/78 ,  C07D265/06 ,  C07D277/42 ,  C07D213/69

CPC分类号： C07D239/545 ,  C07C217/80 ,  C07C217/84 ,  C07C217/92 ,  C07C233/25 ,  C07C233/75 ,  C07C2601/14 ,  C07D211/72 ,  C07D213/64 ,  C07D213/69 ,  C07D213/74 ,  C07D213/79 ,  C07D213/80 ,  C07D213/82 ,  C07D215/22 ,  C07D215/56 ,  C07D217/22 ,  C07D217/24 ,  C07D231/38 ,  C07D233/88 ,  C07D233/96 ,  C07D235/30 ,  C07D237/04 ,  C07D237/20 ,  C07D237/32 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/54 ,  C07D239/557 ,  C07D239/78 ,  C07D239/84 ,  C07D239/95 ,  C07D239/96 ,  C07D241/20 ,  C07D255/02 ,  C07D261/12 ,  C07D263/32 ,  C07D263/34 ,  C07D263/48 ,  C07D265/06 ,  C07D265/10 ,  C07D265/26 ,  C07D265/36 ,  C07D277/20 ,  C07D277/28 ,  C07D277/34 ,  C07D277/38 ,  C07D277/42 ,  C07D401/12 ,  C07D401/14 ,  C07D405/06 ,  C07D405/12 ,  C07D405/14 ,  C07D407/06 ,  C07D409/06 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

摘要： The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect.A pharmaceutical composition having a P2X3 and/or P2X2/3 receptor antagonistic effect comprising a compound of the formula (I): wherein ring A is substituted or unsubstituted 5 to 7-membered cycloalkane, substituted or unsubstituted 5 to 7-membered cycloalkene or the like; C is a carbon atom; —X— is —N(R16)— or the like; R16 is hydrogen, substituted or unsubstituted alkyl or the like; R7 is substituted or unsubstituted 5- or 6-membered heteroaryl, substituted or unsubstituted 6 to 10 membered aryl; Q1 and Q2 are each independently a carbon atom or a nitrogen atom; -L- is —O—, —S— or the like; R6 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl or the like; R2 is hydrogen, hydroxy or the like, or its pharmaceutically acceptable salt or a solvate thereof.

摘要翻译： 本发明提供具有P2X3和/或P2X2 / 3受体拮抗作用的新化合物。 一种具有P2X3和/或P2X2 / 3受体拮抗作用的药物组合物，其包含式（I）化合物：其中环A是取代或未取代的5至7元环烷烃，取代或未取代的5至7元环烯烃或 喜欢; C是碳原子; -X-是-N（R 16） - 等; R 16是氢，取代或未取代的烷基等; R 7是取代或未取代的5元或6元杂芳基，取代或未取代的6至10元芳基; Q1和Q2各自独立地为碳原子或氮原子; -L-是-O-，-S-等; R6是取代或未取代的环烷基，取代或未取代的环烯基等; R2是氢，羟基等，或其药学上可接受的盐或其溶剂合物。

公开(公告)号：US20070210804A1

公开(公告)日：2007-09-13

申请号：US11714448

申请日：2007-03-06

申请人： Takeshi Endoh

发明人： Takeshi Endoh

IPC分类号： G01R31/08

CPC分类号： G01R31/025

摘要： A load abnormality detecting system and method for detecting the burnout and short circuit of a load are provided. A voltage generator (10) generates a specified voltage Vs in accordance with a load current IL. A judging device (4) compares a signal corresponding to this voltage (Vs) with a specified reference value (T1, T2) to judge whether a load (2) has any abnormality. A selector (6) causes the burnout reference value (T1) to be inputted to the judging device (4) and controls the voltage generator (10) to use a first resistance value when checking the burnout of the load (2) while causing the short-circuit reference value (T2) to be inputted to the judging device (4) and controlling the voltage generator (10) to use a second resistance value when checking the short circuit of the load (2).

摘要翻译： 提供一种用于检测负载的烧坏和短路的负载异常检测系统和方法。 电压发生器（10）根据负载电流IL产生规定的电压Vs。 判断装置（4）将与该电压（Vs）对应的信号与规定的基准值（T 1，T 2）进行比较，判断负载（2）是否有异常。 选择器（6）使得烧断参考值（T 1）被输入到判断装置（4），并且当检查负载（2）的烧坏时，控制电压发生器（10）使用第一电阻值，同时引起 输入到判断装置（4）的短路参考值（T 2），并且在检查负载（2）的短路时控制电压发生器（10）使用第二电阻值。

公开(公告)号：US08575197B2

公开(公告)日：2013-11-05

申请号：US13121072

申请日：2009-09-24

申请人： Hiroyuki Kai ,  Yoshiyuki Taoda ,  Takeshi Endoh ,  Kentaro Asahi ,  Hiroyuki Tobinaga

发明人： Hiroyuki Kai ,  Yoshiyuki Taoda ,  Takeshi Endoh ,  Kentaro Asahi ,  Hiroyuki Tobinaga

IPC分类号： A61K31/4418 ,  A61K31/443 ,  A61K31/4439 ,  A61K31/422 ,  A61K31/4245 ,  A61K31/402 ,  A61K31/4025 ,  C07D207/38 ,  C07D271/06 ,  C07D261/08 ,  C07D409/10 ,  C07D403/14 ,  C07D413/14 ,  C07D401/04

CPC分类号： C07D487/04 ,  C07D207/38 ,  C07D401/04 ,  C07D401/10 ,  C07D403/04 ,  C07D405/14 ,  C07D409/10 ,  C07D409/14 ,  C07D413/10 ,  C07D413/14 ,  C07D417/04

摘要： The present invention provides a novel P2X3 and/or P2X2/3 receptor antagonist.A compound represented by the formula (I): wherein Z1 is optionally protected hydroxy, etc.; Z2 is —C(═O)—, etc.; Z3a and Z3b are taken together ═O or ═S; t is an integer of 0 to 4; R4a and R4b are each independently, hydrogen or substituted or unsubstituted lower alkyl, etc.; m and n are each independently an integer of 0 to 2; k is an integer of 0 or 1; Ring A is an aromatic carbocyclic ring or a heterocyclic ring, etc.; B is aromatic carbocyclic ring-diyl or heterocyclic ring-diyl, etc.; R1a and R1b are each independently halogen, hydroxy, substituted or unsubstituted lower alkyl, etc.; R2 is substituted or unsubstituted alkyl, etc.; R3 is substituted or unsubstituted alkyl, substituted or unsubstituted aryl or a substituted or unsubstituted heterocyclic group, etc.; or its pharmaceutically acceptable salt, or a solvate thereof is provided.

摘要翻译： 本发明提供了一种新型的P2X3和/或P2X2 / 3受体拮抗剂。 由式（I）表示的化合物：其中Z 1任选被保护的羟基等; Z2是-C（= O） - 等; Z3a和Z3b在一起= O或= S; t为0〜4的整数; R4a和R4b各自独立地为氢或取代或未取代的低级烷基等; m和n各自独立地为0〜2的整数。 k是0或1的整数; 环A是芳族碳环或杂环等; B是芳族碳环环 - 二基或杂环环二基等; R1a和R1b各自独立地为卤素，羟基，取代或未取代的低级烷基等; R2是取代或未取代的烷基等; R3是取代或未取代的烷基，取代或未取代的芳基或取代或未取代的杂环基等; 或其药学上可接受的盐或其溶剂合物。

公开(公告)号：US20130225596A1

公开(公告)日：2013-08-29

申请号：US13816085

申请日：2011-08-09

申请人： Hiroyuki Kai ,  Takeshi Endoh ,  Sae Jikihara ,  Kentaro Asahi ,  Tohru Horiguchi

发明人： Hiroyuki Kai ,  Takeshi Endoh ,  Sae Jikihara ,  Kentaro Asahi ,  Tohru Horiguchi

IPC分类号： C07C233/75 ,  C07D239/84 ,  C07D213/74 ,  C07C217/84 ,  C07D211/72 ,  C07D405/06 ,  C07C217/80 ,  C07D413/12 ,  C07D409/12 ,  C07D409/06 ,  C07D277/28 ,  C07D401/14 ,  C07D237/04

CPC分类号： C07D239/545 ,  C07C217/80 ,  C07C217/84 ,  C07C217/92 ,  C07C233/25 ,  C07C233/75 ,  C07C2601/14 ,  C07D211/72 ,  C07D213/64 ,  C07D213/69 ,  C07D213/74 ,  C07D213/79 ,  C07D213/80 ,  C07D213/82 ,  C07D215/22 ,  C07D215/56 ,  C07D217/22 ,  C07D217/24 ,  C07D231/38 ,  C07D233/88 ,  C07D233/96 ,  C07D235/30 ,  C07D237/04 ,  C07D237/20 ,  C07D237/32 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D239/54 ,  C07D239/557 ,  C07D239/78 ,  C07D239/84 ,  C07D239/95 ,  C07D239/96 ,  C07D241/20 ,  C07D255/02 ,  C07D261/12 ,  C07D263/32 ,  C07D263/34 ,  C07D263/48 ,  C07D265/06 ,  C07D265/10 ,  C07D265/26 ,  C07D265/36 ,  C07D277/20 ,  C07D277/28 ,  C07D277/34 ,  C07D277/38 ,  C07D277/42 ,  C07D401/12 ,  C07D401/14 ,  C07D405/06 ,  C07D405/12 ,  C07D405/14 ,  C07D407/06 ,  C07D409/06 ,  C07D409/12 ,  C07D413/12 ,  C07D417/12 ,  C07D417/14

摘要： The present invention provides novel compounds having a P2X3 and/or P2X2/3 receptor antagonistic effect.A pharmaceutical composition having a P2X3 and/or P2X2/3 receptor antagonistic effect comprising a compound of the formula (I): wherein ring A is substituted or unsubstituted 5 to 7-membered cycloalkane, substituted or unsubstituted 5 to 7-membered cycloalkene or the like; C is a carbon atom; —X— is —N(R16)— or the like; R16 is hydrogen, substituted or unsubstituted alkyl or the like; R7 is substituted or unsubstituted 5- or 6-membered heteroaryl, substituted or unsubstituted 6 to 10 membered aryl; Q1 and Q2 are each independently a carbon atom or a nitrogen atom; -L- is —O—, —S— or the like; R6 is substituted or unsubstituted cycloalkyl, substituted or unsubstituted cycloalkenyl or the like; R2 is hydrogen, hydroxy or the like, or its pharmaceutically acceptable salt or a solvate thereof.

摘要翻译： 本发明提供具有P2X3和/或P2X2 / 3受体拮抗作用的新化合物。 一种具有P2X3和/或P2X2 / 3受体拮抗作用的药物组合物，其包含式（I）化合物：其中环A是取代或未取代的5至7元环烷烃，取代或未取代的5至7元环烯烃或 喜欢; C是碳原子; -X-是-N（R 16） - 等; R 16是氢，取代或未取代的烷基等; R 7是取代或未取代的5元或6元杂芳基，取代或未取代的6至10元芳基; Q1和Q2各自独立地为碳原子或氮原子; -L-是-O-，-S-等; R6是取代或未取代的环烷基，取代或未取代的环烯基等; R2是氢，羟基等，或其药学上可接受的盐或其溶剂合物。

公开(公告)号：US07525318B2

公开(公告)日：2009-04-28

申请号：US11714448

申请日：2007-03-06

申请人： Takeshi Endoh

发明人： Takeshi Endoh

IPC分类号： G01R31/08

CPC分类号： G01R31/025

摘要： A load abnormality detecting system and method for detecting the burnout and short circuit of a load are provided. A voltage generator (10) generates a specified voltage Vs in accordance with a load current IL. A judging device (4) compares a signal corresponding to this voltage (Vs) with a specified reference value (T1, T2) to judge whether a load (2) has any abnormality. A selector (6) causes the burnout reference value (T1) to be inputted to the judging device (4) and controls the voltage generator (10) to use a first resistance value when checking the burnout of the load (2) while causing the short-circuit reference value (T2) to be inputted to the judging device (4) and controlling the voltage generator (10) to use a second resistance value when checking the short circuit of the load (2).

摘要翻译： 提供一种用于检测负载的烧坏和短路的负载异常检测系统和方法。 电压发生器（10）根据负载电流IL产生规定的电压Vs。 判断装置（4）将与该电压（Vs）对应的信号与规定的基准值（T1，T2）进行比较，判断负载（2）是否有异常。 选择器（6）使得将烧坏参考值（T1）输入到判断装置（4），并且当检查负载（2）的烧坏同时使电压发生器（10）使用第一电阻值，同时使 输入到判断装置（4）的短路基准值（T2），并且在检查负载（2）的短路时，控制电压发生器（10）使用第二电阻值。

公开(公告)号：US5548096A

公开(公告)日：1996-08-20

申请号：US327490

申请日：1994-10-21

申请人： Yoshio Akasaka ,  Kenichi Kakijima ,  Takeshi Endoh ,  Goro Uchida ,  Masaaki Tanaka ,  Takefumi Fujie ,  Daiji Sukawa ,  Satoshi Endoh ,  Hideo Saitoh ,  Takashi Kubo

发明人： Yoshio Akasaka ,  Kenichi Kakijima ,  Takeshi Endoh ,  Goro Uchida ,  Masaaki Tanaka ,  Takefumi Fujie ,  Daiji Sukawa ,  Satoshi Endoh ,  Hideo Saitoh ,  Takashi Kubo

IPC分类号： B23K11/31 ,  B23K37/04 ,  B23K11/11 ,  B23K11/24 ,  B23K37/00

CPC分类号： B23K37/0443 ,  B23K11/315

摘要： A method for assembling a motor vehicle body by fixing relative positional relationship among a plurality of motor vehicle body constituent parts by means of positioning members provided in a welding jig which is disposed on each side of an assembly station and, in this condition, welding together the plurality of motor vehicle body constituent parts at a plurality of tack-welding locations. First welding guns of indirect feeding type are mounted on the welding jig to weld a part of the tack-welding portions. A welding robot having mounted thereon a second welding gun is disposed outside the welding jig. The above-described part of the tack-welding portions are welded by supplying electric power from the second welding gun to the first welding guns by pinching, by the second welding gun, feeder terminals of the first welding guns in a condition in which the above-described part of the tack-welding portions are being pinched by the first welding guns. The remaining of the tack-welding portions are thereafter welded by the second welding gun.

摘要翻译： 通过借助于设置在组装工位的每一侧的焊接夹具中的定位构件固定多个机动车车身构成部件之间的相对位置关系，并且在这种状态下焊接在一起的方式来组装机动车体的方法 所述多个机动车体构成部件在多个定位焊接位置。 第一个间接进给型焊枪安装在焊接夹具上以焊接部分焊接部分。 安装有第二焊枪的焊接机器人设置在焊接夹具的外部。 上述部分焊接部分通过从第二焊枪向第一焊枪提供电力，通过第二焊枪将上述第一焊枪的馈线端子夹在上述状态下进行焊接 定位焊接部分的描述部分被第一焊枪夹住。 其后的焊接部分由第二焊枪焊接。

公开(公告)号：US09150546B2

公开(公告)日：2015-10-06

申请号：US13201209

申请日：2010-02-10

申请人： Hiroyuki Kai ,  Takayuki Kameyama ,  Tsuyoshi Hasegawa ,  Miho Oohara ,  Yukio Tada ,  Takeshi Endoh

发明人： Hiroyuki Kai ,  Takayuki Kameyama ,  Tsuyoshi Hasegawa ,  Miho Oohara ,  Yukio Tada ,  Takeshi Endoh

IPC分类号： A61K31/535 ,  A61K31/53 ,  C07D403/06 ,  C07D251/46 ,  C07D251/52 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D413/12

CPC分类号： C07D251/46 ,  C07D251/16 ,  C07D251/44 ,  C07D251/52 ,  C07D401/06 ,  C07D401/12 ,  C07D401/14 ,  C07D403/04 ,  C07D403/06 ,  C07D403/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D413/12

摘要： The present invention provides a novel P2X3 and/or P2X2/3 receptor antagonist.A compound represented by the formula (I): wherein Ra, Rb and Rc are, (a) Ra and Rb are taken together ═Z; and Rc is a group represented by R1c; or (b) Rb and Rc are taken together to form a bond; and Ra is a group represented by —Y—R1a; R1a and R1c are each independently hydrogen, substituted or unsubstituted alkyl, etc.; R2 and R3 are each independently substituted or unsubstituted aryl, etc.; R4a and R4b are each independently hydrogen, substituted or unsubstituted alkyl, etc.; X is —N(R5)—, etc.; R5 is hydrogen, substituted or unsubstituted lower alkyl, etc.; —Y— is —O—, etc.; ═Z is ═O, etc.; and n is an integer of 0 to 4.

摘要翻译： 本发明提供了一种新型的P2X3和/或P2X2 / 3受体拮抗剂。 由式（I）表示的化合物：其中Ra，Rb和Rc为（a）Ra和Rb一起为= Z; Rc为由R1c表示的基团; 或（b）Rb和Rc一起形成键; 并且R a是由-Y-R 1a表示的基团; R1a和R1c各自独立地为氢，取代或未取代的烷基等; R2和R3各自独立地是取代或未取代的芳基等; R4a和R4b各自独立地为氢，取代或未取代的烷基等; X是-N（R 5） - 等; R5是氢，取代或未取代的低级烷基等; -Y-是-O-等; ═Z是═O等; n为0〜4的整数。

公开(公告)号：US08948673B2

公开(公告)日：2015-02-03

申请号：US13757136

申请日：2013-02-01

申请人： Katsunori Suto ,  Norihiko Aze ,  Takeshi Endoh ,  Masayuki Kami ,  Toru Kobayashi ,  Kohta Shiodera

发明人： Katsunori Suto ,  Norihiko Aze ,  Takeshi Endoh ,  Masayuki Kami ,  Toru Kobayashi ,  Kohta Shiodera

IPC分类号： G03G15/20

CPC分类号： G03G15/206 ,  G03G15/2053 ,  G03G2215/2035

摘要： A fixing-unit roller includes: a core bar; and an elastic layer formed on an outer peripheral surface of the core bar. The elastic layer is formed from a porous material that contains a plurality of cells. Cells in a cross section obtained by cutting across the porous material are 0.1 μm or greater and 50 μm or less in size. A ratio of an area occupied by composite cells, which are made of partially-overlapping spherical cells, in a 200-μm square in the cross section to an area of the square is 60% or greater and 70% or less.

摘要翻译： 定影单元辊包括：芯棒; 以及形成在芯棒的外周面上的弹性层。 弹性层由包含多个电池的多孔材料形成。 通过切割多孔材料获得的横截面中的细胞的尺寸为0.1μm以上且50μm以下。 由横截面为200μm正方形的由部分重叠的球形电池制成的复合电池占据的面积与正方形面积的比率为60％以上且70％以下。