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公开(公告)号:US20140056859A1
公开(公告)日:2014-02-27
申请号:US14009018
申请日:2013-03-30
CPC分类号: A61K35/34 , A61K9/70 , A61K35/44 , A61L27/3834 , A61L27/3886 , A61L27/54 , A61L2300/414 , A61L2430/20 , C12N5/0657 , C12N5/0697 , C12N2501/01 , C12N2501/04 , C12N2501/165 , C12N2502/1329 , C12N2502/1347 , C12N2502/28 , C12N2506/02 , A61K2300/00
摘要: The present invention provides a method for producing a myocardial sheet using a group of cells derived from embryonic stem cells. This method is characterized by mixing Flk/KDR positive cells, cardiomyocytes, endothelial cells, and mural cells, all derived from embryonic stem cells, and culturing the mixed cells. Furthermore, the myocardial sheet can be used as a therapeutic agent for heart diseases since VEGF is released from the sheet.
摘要翻译: 本发明提供使用源自胚胎干细胞的一组细胞产生心肌片的方法。 该方法的特征在于混合来自胚胎干细胞的Flk / KDR阳性细胞,心肌细胞,内皮细胞和壁细胞,并培养混合细胞。 此外,心肌片可用作心脏病的治疗剂,因为VEGF从片材中释放出来。
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公开(公告)号:US09623052B2
公开(公告)日:2017-04-18
申请号:US14009018
申请日:2012-03-30
CPC分类号: A61K35/34 , A61K9/70 , A61K35/44 , A61L27/3834 , A61L27/3886 , A61L27/54 , A61L2300/414 , A61L2430/20 , C12N5/0657 , C12N5/0697 , C12N2501/01 , C12N2501/04 , C12N2501/165 , C12N2502/1329 , C12N2502/1347 , C12N2502/28 , C12N2506/02 , A61K2300/00
摘要: The present invention provides a method for producing a myocardial sheet using a group of cells derived from embryonic stem cells. This method is characterized by mixing Flk/KDR positive cells, cardiomyocytes, endothelial cells, and mural cells, all derived from embryonic stem cells, and culturing the mixed cells. Furthermore, the myocardial sheet can be used as a therapeutic agent for heart diseases since VEGF is released from the sheet.
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公开(公告)号:US20120264923A1
公开(公告)日:2012-10-18
申请号:US13518932
申请日:2010-12-27
申请人: Yutaka Ikeda , Jun Yamashita , Ichiro Hijikuro , Satoshi Imuta , Yasuhiro HIroki , Takashi Takahashi
发明人: Yutaka Ikeda , Jun Yamashita , Ichiro Hijikuro , Satoshi Imuta , Yasuhiro HIroki , Takashi Takahashi
CPC分类号: A61K47/14 , A61K9/0019 , A61K9/0024 , A61K47/08 , A61K47/10 , A61K47/22 , A61K47/26 , C07H15/10 , C09K19/06
摘要: The present invention relates to a liquid crystal compound that can be used as a base for injection formulations. The present invention provides an amphipathic compound having the following general formula (I): wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes an integer from 0 to 2, m denotes the integer 1 or 2, and R denotes a hydrophilic group generated by removal of one hydroxyl group from any one selected from the group consisting of glycerol, erythritol, pentaerythritol, diglycerol, triglycerol, xylose, sorbitol, ascorbic acid, glucose, galactose, mannose, dipentaerythritol, maltose, mannitol, and xylitol; as well as a base for injection formulations and depot formulation comprising the same.
摘要翻译: 本发明涉及可用作注射制剂的基质的液晶化合物。 本发明提供具有以下通式(I)的两亲化合物:其中X和Y各自表示氢原子或一起表示氧原子,n表示0至2的整数,m表示整数1或2,并且 R表示通过从选自甘油,赤藓糖醇,季戊四醇,双甘油,三甘油,木糖,山梨醇,抗坏血酸,葡萄糖,半乳糖,甘露糖,二季戊四醇,麦芽糖,甘露糖醇,甘露糖醇, 和木糖醇; 以及用于注射制剂的基料和包含其的包含药剂的制剂。
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公开(公告)号:USD572707S1
公开(公告)日:2008-07-08
申请号:US29281067
申请日:2007-06-14
申请人: Jun Yamashita , Cai Zhong Tian
设计人: Jun Yamashita , Cai Zhong Tian
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公开(公告)号:US20050223722A1
公开(公告)日:2005-10-13
申请号:US10509637
申请日:2003-03-27
申请人: Jun Yamashita , Yasushi Takagi , Susumu Saruta , Munehiro Horie , Tsutomu Sakuma
发明人: Jun Yamashita , Yasushi Takagi , Susumu Saruta , Munehiro Horie , Tsutomu Sakuma
CPC分类号: F25D29/00 , F25B5/00 , F25B5/02 , F25B9/002 , F25B2400/04 , F25B2400/0409 , F25B2400/0411 , F25B2400/12 , F25B2500/26 , F25B2600/025 , F25B2600/111 , F25B2600/2511 , F25B2700/21161 , F25B2700/21174 , F25B2700/21175 , F25D17/065 , F25D2400/04 , F25D2700/12 , Y02B30/743 , Y10S236/09
摘要: A refrigerator has a refrigerating cycle sequentially connecting a compressor, a condenser, a drawing mechanism, and evaporator, an accumulator, an inlet temperature sensor and an outlet temperature sensor for detecting the temperatures of the inlet and outlet of the evaporator, and a cooling fan for cooling the compressor. When the difference between the temperature detected by the inlet temperature sensor and the temperature detected by the outlet temperature sensor is a predetermined value or more, the cooling fan is stopped.
摘要翻译: 冰箱具有依次连接压缩机,冷凝器,牵引机构和蒸发器的冷冻循环,蓄热器,入口温度传感器和用于检测蒸发器的入口和出口温度的出口温度传感器,以及冷却风扇 用于冷却压缩机。 当由入口温度传感器检测到的温度与由出口温度传感器检测的温度之间的差异是预定值或更大时,停止冷却风扇。
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公开(公告)号:US20050002809A1
公开(公告)日:2005-01-06
申请号:US10858476
申请日:2004-06-02
CPC分类号: B60T8/4031 , F04B1/0413 , F04B9/042
摘要: A plunger pump, includes: a plunger pump unit including a pump chamber and a plunger for pressing a hydraulic fluid in the pump chamber to perform a discharging operation of the hydraulic fluid; a motor; and a cam portion driven by the motor to rotate and press the plunger. The cam portion has at least two discharge regions for pressing the plunger and a suction region formed between the discharge region. The plunger performs the discharging operation two times or more by one rotation of the cam portion.
摘要翻译: 一种柱塞泵,包括:柱塞泵单元,其包括泵室和用于对泵室中的液压流体进行按压以执行液压流体的排放操作的柱塞; 电机 以及由马达驱动以旋转并按压柱塞的凸轮部分。 凸轮部具有用于按压柱塞的至少两个排出区域和形成在排出区域之间的吸入区域。 柱塞通过凸轮部分的一次旋转执行两次或更多次的排出操作。
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公开(公告)号:US6071845A
公开(公告)日:2000-06-06
申请号:US761697
申请日:1996-12-06
申请人: Nobuhiro Tsujimoto , Michinori Suzuki , Kei Tsukahara , Shigeru Ikai , Koji Imaoka , Yoshiyuki Kai , Jun Yamashita
发明人: Nobuhiro Tsujimoto , Michinori Suzuki , Kei Tsukahara , Shigeru Ikai , Koji Imaoka , Yoshiyuki Kai , Jun Yamashita
CPC分类号: C08F10/00 , C07F17/00 , C08F36/04 , C08F4/68 , C08F4/63908 , C08F4/63912 , C08F4/6392 , Y10S526/943
摘要: A catalyst obtained by contacting (A) a compound of a transition metal of the group V of the Periodic Table represented by formula (I):R.sub.n M(O).sub.m X.sub.p .cndot.L.sub.a (I)wherein M represents a transition metal of the group V of the Periodic Table; R represents a cyclopentadienyl group, a substituted cyclopentadienyl group, an indenyl group, a substituted indenyl group, a fluorenyl group or a substituted fluorenyl group; O represents an oxygen atom; X represents a hydrogen atom, a halogen atom, a hydrocarbon group having 1 to 20 carbon atoms, an alkoxy group, an aryloxy group or an amido group; L represents a Lewis basic compound; n, m, and p each represent an integer selected to make a combination of (n=1, m=1, p=2), (n=1, m=0, p=3), (n=2, m=0, p=1) or (n=1, m=0, p=2); and a represents 0, 1 or 2, and (B) at least one of (B1) an ionic compound comprising a non-coordinating anion and a cation and (B2) an aluminoxane, provided that the component (B) is an ionic compound comprising a non-coordinating anion and a cation (B1) when the combination of n, m, and p of the component (A) is (n=2, m=0, p=1) or (n=1, m=0, p=2).
摘要翻译: 通过使(A)由式(I)表示的周期表的第V族的过渡金属的化合物:RnM(O)m X pLa(I)与M表示第V族的过渡金属 周期表; R表示环戊二烯基,取代的环戊二烯基,茚基,取代的茚基,芴基或取代的芴基; O表示氧原子; X表示氢原子,卤素原子,碳原子数1〜20的烃基,烷氧基,芳氧基或酰胺基; L代表路易斯碱性化合物; n,m和p各自表示选择以使(n = 1,m = 1,p = 2),(n = 1,m = 0,p = 3),(n = = 0,p = 1)或(n = 1,m = 0,p = 2); 和(B)包含非配位阴离子和阳离子的离子化合物和(B2)铝氧烷中的至少一种,(B)组分(B)是离子化合物 当组分(A)的n,m和p的组合为(n = 2,m = 0,p = 1)或(n = 1,m = 1)时,包含非配位阴离子和阳离子(B1) 0,p = 2)。
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公开(公告)号:US08703922B2
公开(公告)日:2014-04-22
申请号:US13518932
申请日:2010-12-27
申请人: Yutaka Ikeda , Jun Yamashita , Ichiro Hijikuro , Satoshi Imuta , Yasuhiro Hiroki , Takashi Takahashi
发明人: Yutaka Ikeda , Jun Yamashita , Ichiro Hijikuro , Satoshi Imuta , Yasuhiro Hiroki , Takashi Takahashi
IPC分类号: C07H15/00 , C07H15/04 , A61K31/70 , A61K31/7028 , C07C57/03
CPC分类号: A61K47/14 , A61K9/0019 , A61K9/0024 , A61K47/08 , A61K47/10 , A61K47/22 , A61K47/26 , C07H15/10 , C09K19/06
摘要: The present invention relates to a liquid crystal compound that can be used as a base for injection formulations. The present invention provides an amphipathic compound having the following general formula (I): wherein X and Y each denotes a hydrogen atom or together denote an oxygen atom, n denotes an integer from 0 to 2, m denotes the integer 1 or 2, and R denotes a hydrophilic group generated by removal of one hydroxyl group from any one selected from the group consisting of glycerol, erythritol, pentaerythritol, diglycerol, triglycerol, xylose, sorbitol, ascorbic acid, glucose, galactose, mannose, dipentaerythritol, maltose, mannitol, and xylitol; as well as a base for injection formulations and depot formulation comprising the same.
摘要翻译: 本发明涉及可用作注射制剂的基质的液晶化合物。 本发明提供具有以下通式(I)的两亲化合物:其中X和Y各自表示氢原子或一起表示氧原子,n表示0至2的整数,m表示整数1或2,并且 R表示通过从选自甘油,赤藓糖醇,季戊四醇,双甘油,三甘油,木糖,山梨醇,抗坏血酸,葡萄糖,半乳糖,甘露糖,二季戊四醇,麦芽糖,甘露糖醇,甘露糖醇, 和木糖醇; 以及用于注射制剂的基料和包含其的包含药剂的制剂。
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公开(公告)号:US08267040B2
公开(公告)日:2012-09-18
申请号:US10589272
申请日:2005-02-15
申请人: Kiyotaka Ishibashi , Junichi Kitagawa , Singo Furui , Cai Zhong Tian , Jun Yamashita , Nobuhiko Yamamoto , Tetsuya Nishizuka , Toshihisa Nozawa , Shinya Nishimoto , Tamaki Yuasa
发明人: Kiyotaka Ishibashi , Junichi Kitagawa , Singo Furui , Cai Zhong Tian , Jun Yamashita , Nobuhiko Yamamoto , Tetsuya Nishizuka , Toshihisa Nozawa , Shinya Nishimoto , Tamaki Yuasa
IPC分类号: C23C16/00 , C23F1/00 , H01L21/306
CPC分类号: H01J37/32192 , H01J37/32238
摘要: In a plasma processing apparatus that processes a wafer in a process vessel by plasma generated by the supply of a microwave, a transmissive window has, in a center area of its lower surface, a hanging portion made of the same material as a material of the transmissive window. Between an outer peripheral surface of the hanging portion and a sidewall inner surface continuing from a support part, a gap is formed, the gap having a gap length of 0.5 to 10 mm, more preferably 0.5 to 5 mm. The generation of a strong electric field and plasma at a contact point is inhibited and an amount of sputtered particles, radicals, or the like reaching the wafer is also reduced.
摘要翻译: 在通过供给微波产生的等离子体处理处理容器中的晶片的等离子体处理装置中,透光窗口在其下表面的中心区域具有由与材料相同的材料制成的悬挂部分 透光窗。 在悬挂部的外周面与从支撑部延续的侧壁内表面之间形成有间隙,间隙长度为0.5〜10mm,更优选为0.5〜5mm。 在接触点处产生强电场和等离子体被抑制,并且溅射的颗粒,自由基等到达晶片的量也减少。
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公开(公告)号:USD658691S1
公开(公告)日:2012-05-01
申请号:US29400581
申请日:2011-08-30
申请人: Kouki Suzuki , Jun Yamashita , Masakazu Ban , Atsushi Ueda
设计人: Kouki Suzuki , Jun Yamashita , Masakazu Ban , Atsushi Ueda
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