摘要:
The present invention relates to a hydroxamic acid derivative of the formula (I) wherein each symbol is as defined in the specification, a pharmacologically acceptable salt thereof, a pharmaceutical composition containing the derivative or a salt thereof, and to pharmaceutical use thereof. The hydroxamic acid derivative and a pharmacologically acceptable salt thereof of the present invention have an inhibitory activity of TNF &agr; production, and are useful for, for example, the prophylaxis and treatment of the diseases such as autoimmune diseases and inflammatory diseases (e.g., sepsis, MOF, rheumatoid arthritis, Crohn's disease, cachexia, myasthenia gravis, systemic lupus erythematosus, asthma, I type diabetes, psoriasis and the like), and the like.
摘要:
A coating composition has excellent application workability, facilitates thick coating, rarely causes cracks at an initial drying stage, and provides a dried film having excellent tensile properties and adhesiveness. The composition contains an aggregate and an emulsion with a polymer particle dispersed in an aqueous medium. The polymer particle includes 40% to 98% of a unit formed by polymerizing an alkyl(meth)acrylate monomer, the alkyl group having 4 to 14 carbon atoms, 0.1% to 5% of a unit formed by polymerizing an ethylenically unsaturated carboxylic acid monomer, 1% to 20% of a unit formed by polymerizing a vinyl monomer having a cyano group, 1% to 20% of a unit formed by polymerizing a reaction product of a (meth)acrylic acid and a monofunctional epoxy compound, and 0% to 50% of a unit formed by copolymerizing at least one of the above monomers with another monomer.
摘要:
A wireless communication apparatus is provided. The wireless communication apparatus includes: detection means that detects that there is another wireless communication apparatus around the wireless communication apparatus; comparison means that compares a first reference value managed in the wireless communication apparatus with a second reference value managed in the another wireless communication apparatus; means that corrects the first reference value based on the comparison result; and means that announces the first reference value to the another wireless communication apparatus. Frequencies are set such that a frequency of the wireless communication apparatus becomes same as a frequency of still another wireless communication apparatus to which a radio wave of the wireless communication apparatus does not reach but a radio wave of the another wireless communication apparatus reaches.
摘要:
A mobile communication system determines a communication path to implement fast communication by multihop connection. A mobile communication system includes a mobile station, at least one relay station, and a base station and implements packet transmission from the mobile station to the base station through a communication path with an intermediary of at least one relay station or through a communication path without an intermediary of a relay station. The mobile communication system is provided with a communication path determiner for determining a communication path with a largest communication speed or a communication path satisfying a required line quality, based on interference levels of respective signals received at a relay station constituting a communication path between the transmitting station and the receiving station, and at the base station.
摘要:
A semiconductor memory device comprises: a write circuit including a latch circuit configured by two inverters having a positive side power supply terminal supplied with a first voltage and a negative side power supply terminal supplied with a second voltage; and a write state machine controlling the first and second voltages. When writing data to a memory cell, the first voltage is changed to a second value that is lower than a first value. When writing data to a memory cell, the second voltage is changed to a third value that is lower than the second value. The write state machine lowers the second voltage to an intermediate value between the second value and the third value and, while maintaining this intermediate value, lowers the first voltage from the first value to the second value.
摘要:
A communication apparatus is disclosed, which includes an information collection unit, a storage unit, a selection unit, and a route control unit. The information collection unit is configured to collect route information and condition information. The storage unit is configured to store the route information and the connection information. The selection unit is configured to select a connection apparatuses for a terminal apparatus based on the route information and the connection information. The route control unit is configured to control routes from the communication apparatus to the connection apparatus.
摘要:
A semiconductor chip is attached to a lead frame with a filmy organic die-bonding material having a water absorption of 1.5% by volume or less; having a saturation moisture absorption of 1.0% by volume or less, having a residual volatile component in an amount not more than 3.0% by weight, having a modulus of elasticity of 10 MPa or less at a temperature of 250° C. The semiconductor device thus obtained can be free from occurrence of reflow cracks during reflow soldering for the packaging of semiconductor devices.
摘要:
The object of the present invention is to provide an immobilization support having an optimum support surface for immobilizing various types of materials having different properties with specificity, efficiency, and good reproducibility, and to provide a solid phase having improved characteristics by use of the above support. The immobilization support of the present invention is provided with an electrolyte thin film on the surface of the support. This immobilization support can be applied to the fabrication of a solid phase used in, for example, an antigen-antibody reaction, nucleic acid hybridization, a receptor assay, or a biosensor.
摘要:
A channel allocation method for dynamically allocating channels of a plurality of radio interfaces at each access point included in a mesh network is provided. The method includes the steps of (a) acquiring, at each access point, in-node information about the access point itself, and (b) grouping high-traffic access points in a cluster using a same channel set based on the acquired information.
摘要:
An agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, an agent for the prophylaxis and treatment of allergic diseases, an agent for the prophylaxis and treatment of eosinophil-related diseases and an eosinophilia inhibitor, comprising, as an active ingredient, a series of triazole derivatives of the following formula (I) ##STR1## or the following formula (III) ##STR2## wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. A novel monocyclic or bicyclic triazole derivative. The agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, the agent for the prophylaxis and treatment of allergic diseases, the agent for the prophylaxis and treatment of eosinophil-related diseases, the eosinophilia inhibitor and the novel triazole derivative of the present invention all, have superior eosinophilia-inhibitory action and lymphocyte activation-inhibitory action. They are low toxic and persistent in action. They are particularly effective in the treatment of accumulation and activation of eosinophil and lymphocytes, inflammatory respiratory tract diseases, eosinophil-related diseases such as eosinophilia, and immune-related diseases.