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19 条记录 (耗时 0.028 秒)

    Expandable atherectomy burr with metal reinforcement
    1.
    发明授权
    Expandable atherectomy burr with metal reinforcement 有权
    可扩展的粥样斑块切除术与金属加固

    公开(公告)号：US06451037B1

    公开(公告)日：2002-09-17

    申请号：US09721349

    申请日：2000-11-22

    申请人： Verivada Chandrasekaran ,  Thomas J. Hiblar

    发明人： Verivada Chandrasekaran ,  Thomas J. Hiblar

    IPC分类号： A61B1732

    CPC分类号： A61B17/320758 ,  A61B17/320725 ,  A61B2017/320004

    摘要： An atherectomy burr having an operating diameter that is larger than the diameter of a catheter in which the burr is routed. The burr may include a flexible polymeric tube that is plated with an abrasive and that expands when the burr is rotated. Metal fibers are embedded into burr to improve strength and to control the maximum expansion diameter of the burr. The abrasive is plated on the burr by first selectively exposing the underlying metal. The exposed metal is then plated with a layer of metal such as nickel having a slurry of diamond particles disposed therein using an electro and/or electroless plating method. When the burr is rotated, the polymeric tube expands by centrifugal force to ablate a new lumen in the patient's vessel.

    摘要翻译： 一种粥样斑块切除术毛刺，其操作直径大于其中布置毛刺的导管的直径。 毛刺可以包括柔性聚合物管，其被镀有研磨剂并且当毛刺旋转时膨胀。 将金属纤维嵌入毛刺中以提高强度并控制毛刺的最大膨胀直径。 通过首先选择性地暴露下面的金属，将磨料镀在毛刺上。 然后，使用电镀和/或无电镀方法将暴露的金属镀上一层金属如镍，其中金属颗粒的浆料设置在其中。 当毛刺旋转时，聚合物管通过离心力膨胀以消融患者血管中的新腔。

    Methods of forming medical devices
    3.
    发明授权
    Methods of forming medical devices 失效
    形成医疗器械的方法

    公开(公告)号：US06960370B2

    公开(公告)日：2005-11-01

    申请号：US10400762

    申请日：2003-03-27

    申请人： Vittorino Monni ,  Verivada Chandrasekaran ,  Outhay Voraphet

    发明人： Vittorino Monni ,  Verivada Chandrasekaran ,  Outhay Voraphet

    IPC分类号： A61F2/00 ,  C25D5/18 ,  C25D5/36 ,  C25D5/38 ,  C25D7/00 ,  B05D3/00 ,  B05D3/04 ,  C25D5/34

    CPC分类号： C25D5/36 ,  C25D5/18 ,  C25D5/38

    摘要： Medical devices that include oxidizable portions can be plated after a two step activation process that includes successive applications of two aqueous solutions of ammonium bifluoride. Once plated, such materials can be soldered using conventional solders and fluxes. Medical devices can be assembled by soldering together plated materials. Oxidizable materials can be plated with radiopaque materials to yield medical devices that are more visible to fluoroscopy.

    摘要翻译： 包括可氧化部分的医疗装置可以在两步活化过程之后进行电镀，其包括连续使用两种二氟化铵水溶液。 一旦镀覆，这些材料可以使用常规的焊料和焊剂进行焊接。 可以通过将电镀材料焊接在一起来组装医疗器械。 可氧化材料可以用不透射线的材料进行电镀，以产生对荧光透视更为可见的医疗器械。

    Guide wire system for RF recanalization of vascular blockages
    8.
    发明授权
    Guide wire system for RF recanalization of vascular blockages 有权
    导管系统用于射频再通血管阻塞

    公开(公告)号：US06562031B2

    公开(公告)日：2003-05-13

    申请号：US09814142

    申请日：2001-03-20

    申请人： Verivada Chandrasekaran ,  Zihong Guo ,  Brooke Qin Ren ,  Byron Fedie

    发明人： Verivada Chandrasekaran ,  Zihong Guo ,  Brooke Qin Ren ,  Byron Fedie

    IPC分类号： A61B1818

    CPC分类号： A61B18/1492 ,  A61B2017/22038 ,  A61B2017/22094 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00279 ,  A61B2018/00285 ,  A61B2018/0041 ,  A61B2018/00422 ,  A61B2018/00625 ,  A61B2018/1213 ,  A61B2018/1253 ,  A61B2018/1435 ,  A61B2018/144 ,  A61M25/09 ,  A61M25/10 ,  A61M2025/1047

    摘要： A system for recanalizing an occluded blood vessel including a centering catheter employed to center an ablative guide wire within the blood vessel as the guide wire traverses the occlusion. The centering catheter includes a catheter body with an operative lumen through which the ablative guide wire is slidingly disposed. The centering catheter further includes a distally disposed centering mechanism that, when activated, centers the ablative guide wire within the blood vessel as it traverses the occlusion. The centering mechanism can comprise various embodiments including a single inflatable balloon or segmented inflatable balloon, which is in fluid communication with an inflation lumen. An airless preparation lumen may be disposed within the inflation lumen for ease of centering catheter preparation. The ablative guide wire includes insulation that is preferably formed of heat shrink tubing, which is stretched prior or concurrently with the heating process. The ablative guide wire includes a distal ablation tip having a non-traumatic structure and at least one discontinuous feature for creating high current densities for more efficient tissue ablation.

    摘要翻译： 包括定心导管的闭塞血管再通的系统，其用于在引导线穿过闭塞时使血管内的消融引导线居中。 定心导管包括具有操作腔的导管主体，消融导丝通过该导管本体滑动地设置。 定心导管进一步包括一个向远侧配置的定中心机构，当被激活时，该消融导丝在穿过该闭塞时在该血管内居中。 定心机构可以包括各种实施例，包括与充气腔流体连通的单个可充气球囊或分段的可充气球囊。 可以在充气腔内设置无空气制剂腔，以便于使导管制剂居中。 烧蚀导丝包括优选由热收缩管形成的绝缘体，其在加热过程之前或同时被拉伸。 烧蚀导丝包括具有非创伤性结构的远端消融尖端和用于产生高电流密度以用于更有效的组织消融的至少一个不连续特征。

    Atherectomy device for reducing damage to vessels and/or in-vivo stents
    9.
    发明授权
    Atherectomy device for reducing damage to vessels and/or in-vivo stents 失效
    用于减少对血管和/或体内支架的损伤的动脉粥样硬化切除装置

    公开(公告)号：US6015420A

    公开(公告)日：2000-01-18

    申请号：US35734

    申请日：1998-03-05

    申请人： Edward Wulfman ,  Lucas Gordon ,  Robert Barry ,  Brandon Shuman ,  David Dillard ,  Verivada Chandrasekaran

    发明人： Edward Wulfman ,  Lucas Gordon ,  Robert Barry ,  Brandon Shuman ,  David Dillard ,  Verivada Chandrasekaran

    IPC分类号： A61B17/32 ,  A61B17/22

    CPC分类号： A61B17/320758 ,  A61B2017/320004

    摘要： An atherectomy device that may reduce the risk of damage to a vessel wall. One rotatable atherectomy burr has a recessed material removal portion lying between less abrasive proximal and distal shoulders. The shoulders can have a straight, rounded or elliptical taper. The shoulders can perform a cam action when the burr is canted is a vessel, as when passing the burr and guide wire through a tortuous, stenosed vessel path. The shoulders act to align the burr with the path through the vessel, presenting the less abrasive shoulders to the vessel wall while presenting the abrasive portion to a stenosis.

    摘要翻译： 可以减少损伤血管壁的风险的粥样斑块切除装置。 一个可旋转的粥样斑块切除术毛刺具有凹陷的材料去除部分，位于不太磨蚀的近端和远端之间。 肩部可以有一个直的圆形或椭圆形的锥形。 当毛刺倾斜是船只时，肩膀可以执行凸轮动作，当通过毛刺和引导线通过曲折，狭窄的血管路径时。 肩部的作用是将毛刺与通过血管的路径对齐，将较小的磨砂肩膀呈现在血管壁上，同时使研磨部分呈狭窄。

    Medical articles that stimulate endothelial cell migration
    10.
    发明授权
    Medical articles that stimulate endothelial cell migration 失效
    刺激内皮细胞迁移的医学文章

    公开(公告)号：US08118857B2

    公开(公告)日：2012-02-21

    申请号：US11947150

    申请日：2007-11-29

    申请人： Daniel VanCamp ,  Rajesh Radhakrishnan ,  Eric Nielson ,  Verivada Chandrasekaran

    发明人： Daniel VanCamp ,  Rajesh Radhakrishnan ,  Eric Nielson ,  Verivada Chandrasekaran

    IPC分类号： A61F2/82

    CPC分类号： A61N1/326 ,  A61L27/04 ,  A61L27/50 ,  A61L31/022 ,  A61L31/14 ,  A61N1/30

    摘要： A medical article that includes (a) an electronically conductive substrate having a specific conductivity of at least 1 μS/cm and (b) a galvanic couple that includes a first member and a second member arranged in sufficient proximity to each other to generate a localized electric field under physiological conditions. The first and second members are selected such that the galvanic couple exhibits an average plateau current density of at least 25 microamps/cm2 when short circuited in a zero resistance ammeter test at room temperature using a saline electrolyte.

    摘要翻译： 一种医疗制品，其包括（a）具有至少1μS/ cm的比电导率的电子导电基底和（b）包括彼此足够接近地布置的第一构件和第二构件的电偶，以产生局部 生理条件下的电场。 选择第一和第二构件，使得当在室温下使用盐水电解质的零电阻电流表试验中短路时，电偶对的平均平均电流密度至少为25微安/ cm2。