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公开(公告)号:US06825009B2
公开(公告)日:2004-11-30
申请号:US10105101
申请日:2002-03-22
申请人: Vince P. Stanton, Jr. , Jia Liu Wolfe , Tomohiko Kawate , Gregory L. Verdine , Jeffrey Olson , Colin W Dykes
发明人: Vince P. Stanton, Jr. , Jia Liu Wolfe , Tomohiko Kawate , Gregory L. Verdine , Jeffrey Olson , Colin W Dykes
IPC分类号: C12Q168
CPC分类号: C12Q1/6858 , C07H19/10 , C07H19/14 , C07H19/20 , C07H21/00 , C12N9/1252 , C12N15/11 , C12P19/34 , C12Q1/6827 , C12Q1/683 , C12Q1/6872 , C12Q2525/117 , C12Q2523/107 , C12Q2527/107 , C12Q2565/627 , C12Q2525/101
摘要: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
摘要翻译: 本发明涉及通过使用疑似含有多态性的多核苷酸的片段的片段与具有与鉴定多态性的片段互补的序列的寡核苷酸杂交并随后检测寡核苷酸中的并入标记的方法来检测多核苷酸中的多态性的方法 碎片双工。
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公开(公告)号:US06500650B1
公开(公告)日:2002-12-31
申请号:US09655104
申请日:2000-09-05
IPC分类号: C12Q168
CPC分类号: C12Q1/6858 , C07H19/10 , C07H19/14 , C07H19/20 , C07H21/00 , C12N9/1252 , C12N15/11 , C12P19/34 , C12Q1/6827 , C12Q1/683 , C12Q1/6872 , C12Q2525/117 , C12Q2523/107 , C12Q2527/107 , C12Q2565/627 , C12Q2525/101
摘要: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
摘要翻译: 本发明涉及通过使用疑似含有多态性的多核苷酸的片段的片段与具有与鉴定多态性的片段互补的序列的寡核苷酸杂交并随后检测寡核苷酸中的并入标记的方法来检测多核苷酸中的多态性的方法 碎片双工。
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公开(公告)号:US06777188B2
公开(公告)日:2004-08-17
申请号:US10107751
申请日:2002-03-26
IPC分类号: C12Q168
CPC分类号: C07H19/10 , C07H19/14 , C07H19/20 , C07H21/00 , C12N9/1252 , C12N15/11 , C12P19/34 , C12Q1/6827 , C12Q1/6872 , C12Q2565/627 , C12Q2525/101 , C12Q2523/107
摘要: The present invention relates to a method for genotyping a diploid organism by cleaving segments of two alleles such that 7-20 nucleotide fragments that contain a suspected polymorphic locus are produced and comparing the masses of those fragments.
摘要翻译: 本发明涉及通过切割两个等位基因的片段对二倍体生物进行基因分型的方法,从而产生含有疑似多态性位点的7-20个核苷酸片段,并比较这些片段的质量。
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公开(公告)号:US20050053972A1
公开(公告)日:2005-03-10
申请号:US10839686
申请日:2004-05-04
申请人: Vince Stanton , Jia Wolfe , Tomohiko Kawate , Gregory Verdine , Jeffrey Olson
发明人: Vince Stanton , Jia Wolfe , Tomohiko Kawate , Gregory Verdine , Jeffrey Olson
IPC分类号: G01N27/62 , C07H19/04 , C07H19/10 , C07H19/14 , C07H19/20 , C07H21/00 , C12N9/12 , C12N15/09 , C12N15/11 , C12P19/34 , C12Q1/68
CPC分类号: C12Q1/6858 , C07H19/10 , C07H19/14 , C07H19/20 , C07H21/00 , C12N9/1252 , C12N15/11 , C12P19/34 , C12Q1/6827 , C12Q1/683 , C12Q1/6872 , C12Q2525/117 , C12Q2523/107 , C12Q2527/107 , C12Q2565/627 , C12Q2525/101
摘要: The present invention relates to methods for the detection of polymorphism in polynucleotides by using hybridization of fragments of segments of a polynucleotide suspected of containing a polymorphism with an oligonucleotide having a sequence complementary to a fragment identifying the polymorphism and subsequent detection of incorporated labels in the oligonucleotide-fragment duplex.
摘要翻译: 本发明涉及通过使用疑似含有多态性的多核苷酸的片段的片段与具有与鉴定多态性的片段互补的序列的寡核苷酸杂交并随后检测寡核苷酸中的并入标记的方法来检测多核苷酸中的多态性的方法 碎片双工。
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公开(公告)号:US20230382473A1
公开(公告)日:2023-11-30
申请号:US17752402
申请日:2022-05-24
申请人: Jeffrey Olson
发明人: Jeffrey Olson
IPC分类号: B62D53/06
CPC分类号: B62D53/068
摘要: A trailer tandem slide stopping device for facilitating positioning of a trailer tandem includes a guide pin, which insertable into a first hole of a plurality of holes positioned in an outer rail attached to a the trailer. The first hole is positioned past either a rearward or forward end of an inner rail of the tandem trailer. The guide pin abuts the rearward or forward end of the inner rail upon driving a semitruck hitched to the trailer in forward or reverse, respectively, to move the trailer tandem toward the rear or front of the trailer, respectively, at which point a locking pin of the trailer tandem is aligned with and positioned for insertion into a target hole of the plurality of holes. The target hole corresponds to a desired position of the trailer tandem relative to the trailer.
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6.
公开(公告)号:US20140193809A1
公开(公告)日:2014-07-10
申请号:US14073779
申请日:2013-11-06
IPC分类号: C12Q1/68
CPC分类号: C12Q1/686 , C12Q1/6858 , C12Q2525/313
摘要: Methods for determining genotypes and haplotypes of genes are described. Also described are single nucleotide polymorphisms and haplotypes in the ApoE gene and methods of using that information.
摘要翻译: 描述了确定基因的基因型和单体型的方法。 还描述了ApoE基因中的单核苷酸多态性和单倍型以及使用该信息的方法。
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公开(公告)号:US08725266B2
公开(公告)日:2014-05-13
申请号:US12528832
申请日:2008-02-28
申请人: Jeffrey Olson , Naresh Mandava
发明人: Jeffrey Olson , Naresh Mandava
CPC分类号: A61K41/00 , A61K9/0009 , A61K9/0051 , A61K33/24 , A61K33/30 , A61K41/0004 , A61N1/0543 , A61N1/36046 , B82Y5/00 , Y10S977/774 , Y10S977/925
摘要: An improved method for stimulating electrical activity in an eye is provided. Provided is a technique for implanting small, nanometer-sized photoactive devices into an eye to improve electrical activity within an eye or mitigate degradation of electrical response in damaged eyes.
摘要翻译: 提供了用于刺激眼睛中电活动的改进方法。 提供了一种用于将小的纳米级光活性器件植入眼睛中以改善眼睛内的电活动或减轻受损眼睛的电响应降解的技术。
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公开(公告)号:US20100271331A1
公开(公告)日:2010-10-28
申请号:US12428266
申请日:2009-04-22
申请人: Rachid Alameh , Roger Ady , Dale Bengtson , Ricky J. Hoobler , Jin Kim , Jeffrey Olson
发明人: Rachid Alameh , Roger Ady , Dale Bengtson , Ricky J. Hoobler , Jin Kim , Jeffrey Olson
CPC分类号: G06F3/0421 , G06F3/04883 , G06F3/04886
摘要: A touch sensitive display for an electronic device includes a display (201) for presenting information to a user and at least four infrared transceivers (202,203,204,205) disposed about the display (201). The four or more infrared transceivers (202,203,204,205) can be disposed about the display (201) such that infrared light (206,207,208,209) from each of the infrared transceivers (202,203,204,205) projects across a surface (303) of the display (201). A controller (214), which is operable with the infrared transceivers (202,203,204,205), is configured to detect which of the infrared transceivers (202,203,204,205) has the most reflected signal (702). The controller (214) can then correlate this and other information with one of a plurality of user modes of operation. A control menu (802) can then be presented on the display (301) in accordance with the user mode of operation to mitigate finger blockage.
摘要翻译: 电子设备的触敏显示器包括用于向用户呈现信息的显示器(201)和围绕显示器(201)设置的至少四个红外收发器(202,203,204,205)。 可以围绕显示器(201)布置四个或更多个红外收发器(202,203,204,205),使得来自每个红外收发器(202,203,204,205)的红外光(206,207,208,209)跨过显示器(201)的表面(303)突出。 可与红外收发器(202,203,204,205)一起操作的控制器(214)被配置为检测哪个红外收发器(202,203,204,205)具有最大反射信号(702)。 然后,控制器(214)可以将该信息和其他信息与多个用户操作模式中的一个相关联。 然后可以根据用户操作模式在显示器(301)上呈现控制菜单(802),以减轻手指堵塞。
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公开(公告)号:US20060102817A1
公开(公告)日:2006-05-18
申请号:US11266057
申请日:2005-11-02
申请人: Robert Swartz , Kenton Droppers , Robert Welch , James Janick , Jeffrey Olson , Robert Steele
发明人: Robert Swartz , Kenton Droppers , Robert Welch , James Janick , Jeffrey Olson , Robert Steele
CPC分类号: A47B96/067 , A47B55/02
摘要: A wall-mounted shelving system is provided that is easy to install, allows for a placement which is unlimited by stud location, holds heavy loads, and is easily cleanable. This wall-mounted shelving system includes a track and a bracket engagable with the track. The bracket has a collar for supporting a shelf-carrying pilaster and an engaging element protruding from the collar that includes a floor and an arm projecting upwardly from the floor to define an elbow. The track is adapted to be mounted horizontally on a wall and includes a downwardly open channel at its top and an outwardly projecting ledge at its bottom. The upper extreme of the engaging element arm is received in the channel of the track while the elbow can be supported to rest on the ledge. A pilaster is adapted to then be supported in the collar through an intermediate wedge member, and shelves and other objects can be supported on the pilaster.
摘要翻译: 提供了一种易于安装的壁挂式货架系统,允许通过螺栓位置无限制的放置,承受重载,并且易于清洁。 这种壁挂式货架系统包括一个轨道和一个可与轨道相连接的支架。 支架具有用于支撑搁架的玻璃器皿和从套环突出的接合元件的套环,其包括地板和从地板向上突出以限定肘部的臂。 轨道适于水平地安装在墙壁上,并且在其顶部包括向下开口的通道,在其底部包括向外突出的突出部。 接合元件臂的上端被接收在轨道的通道中,同时可以将肘部支撑在搁架上。 一个皮质适配器然后通过一个中间的楔形构件被支撑在套环中,并且搁板和其他物体可以被支撑在玻璃炉上。
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公开(公告)号:US20130224751A1
公开(公告)日:2013-08-29
申请号:US13796901
申请日:2013-03-12
申请人: Jeffrey Olson , Darren Roy Link
发明人: Jeffrey Olson , Darren Roy Link
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6816 , C12Q1/6827 , C12Q1/686 , C12Q1/6883 , C12Q1/6886 , C12Q2600/172 , C12Q2563/159 , C12Q2565/629 , C12Q2537/143 , C12Q2531/113 , C12Q2535/131
摘要: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.
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