Tissue scaffolds for use in muscoloskeletal repairs
    1.
    发明授权
    Tissue scaffolds for use in muscoloskeletal repairs 有权
    组织支架用于麝香骨骼修复

    公开(公告)号:US07625581B2

    公开(公告)日:2009-12-01

    申请号:US10742136

    申请日:2003-12-19

    IPC分类号: A61K9/14 A61K31/70

    摘要: The present invention includes a tissue scaffold suitable for use in repair and/or regeneration of musculoskeletal tissue when implanted in a body that includes a porous substrate made from a biodegradable, hydrophobic polymer having a modified hyaluronic acid complex dispersed on the surface of and/or, where the modified hyaluronic acid complex is insoluble in water, yet soluble in mixtures of organic and aqueous solvents in which the hydrophobic polymer is soluble.

    摘要翻译: 本发明包括一种组织支架,其适于在植入体内时用于肌肉骨骼组织的修复和/或再生,其包括由可分散在其表面上的具有改性透明质酸复合物的可生物降解的疏水性聚合物制成的多孔底物,和/或 其中改性的透明质酸络合物不溶于水,但可溶于有机和水性溶剂的混合物,其中疏水聚合物可溶于其中。

    Modified hyaluronic acid for use in musculoskeletal tissue repair
    2.
    发明授权
    Modified hyaluronic acid for use in musculoskeletal tissue repair 有权
    用于肌肉骨骼组织修复的改性透明质酸

    公开(公告)号:US07091191B2

    公开(公告)日:2006-08-15

    申请号:US10741511

    申请日:2003-12-19

    IPC分类号: A61K31/70 C08B37/00

    CPC分类号: C08B37/0072 A61K31/728

    摘要: The present invention includes hyaluronic acid complexes of a monovalent alkali metal salt of hyaluronic acid and a tetra alkyl ammonium halide that are suitable for incorporation with tissue scaffolds that are suitable for use in repair and/or regeneration of muscoloskeletal tissue and that include a biodegradable, porous substrate made from a biodegradable, hydrophobic polymer, where the hyaluronic acid complex is substantially insoluble in water at room temperature, yet soluble in mixtures of organic and aqueous solvents in which the selected hydrophobic polymer is soluble.

    摘要翻译: 本发明包括透明质酸的一价碱金属盐和四烷基卤化铵的透明质酸配合物,其适用于与适用于修复和/或再生肌肉骨骼组织的组织支架结合,并且包括可生物降解的, 由可生物降解的疏水性聚合物制成的多孔基材,其中透明质酸络合物在室温下基本上不溶于水,但可溶于选择的疏水性聚合物可溶的有机和水性溶剂的混合物中。

    Biomedical devices containing amphiphilic block copolymers
    8.
    发明授权
    Biomedical devices containing amphiphilic block copolymers 有权
    含有两亲性嵌段共聚物的生物医学装置

    公开(公告)号:US07247692B2

    公开(公告)日:2007-07-24

    申请号:US10954560

    申请日:2004-09-30

    申请人: Walter R. Laredo

    发明人: Walter R. Laredo

    IPC分类号: C08F30/08

    摘要: This invention relates to wettable biomedical devices comprising amphiphilic block copolymers. The amphiphilic block copolymers are useful as internal wetting agents for biomedical applications, such as implantable devices, ophthalmic devices and in one embodiment, contact lenses.

    摘要翻译: 本发明涉及包含两亲嵌段共聚物的可湿性生物医学装置。 两亲性嵌段共聚物可用作生物医学应用的内部润湿剂,例如可植入装置,眼科装置,并且在一个实施方案中为隐形眼镜。

    Hydrophobic acrylic intraocular lens materials
    9.
    发明授权
    Hydrophobic acrylic intraocular lens materials 有权
    疏水性丙烯酸类眼内透镜材料

    公开(公告)号:US08466209B2

    公开(公告)日:2013-06-18

    申请号:US13485447

    申请日:2012-05-31

    摘要: Disclosed are low-tack, hydrophobic, high refractive index, acrylic materials. These materials, especially useful as intraocular lens materials, contain one or more aryl acrylic hydrophobic monomers as principal device-forming monomers, a tack-reducing macromer additive and a glistening-reducing additive. In addition to their use as intraocular lens materials, the present materials are also suitable for use in other implantable ophthalmic devices.

    摘要翻译: 公开了低粘度,疏水性,高折射率,丙烯酸材料。 这些特别用作眼内透镜材料的材料含有一种或多种芳基丙烯酸类疏水性单体作为主要的器件形成单体,降粘大分子添加剂和减少闪光的添加剂。 除了它们用作眼内透镜材料之外,本材料还适用于其它可植入眼科装置。