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1.发明授权
公开(公告)号：US5747285A
公开(公告)日：1998-05-05
申请号：US207900
申请日：1994-03-08
IPC分类号： C07K14/37 , C07K14/375 , C12N9/10 , C12N9/16 , C12N9/88 , C12N15/10 , C12N15/52 , C12N15/80 , C12P37/00 , C12N15/62
CPC分类号： C12N15/52 , C07K14/37 , C07K14/375 , C12N15/1034 , C12N15/80 , C12N9/1029 , C12N9/16 , C12N9/88 , C12P37/00 , C07K2319/00 , C07K2319/02
摘要： A gene expression system and a protein secretion system for eukaryotic, especially fungal, microorganisms has been provided for.
摘要翻译： 已经提供了用于真核的，特别是真菌的微生物的基因表达系统和蛋白质分泌系统。
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公开(公告)号：US5217878A
公开(公告)日：1993-06-08
申请号：US162184
申请日：1988-02-29
IPC分类号： C12N1/20 , C12N1/21 , C12N9/54 , C12N15/00 , C12N15/09 , C12N15/57 , C12N15/75 , C12N15/87 , C12N15/90 , C12R1/07
摘要： Novel methods and novel industrial Bacillus strains are provided for enhanced production of serine protease. Plasmid constructs comprising the serine protease gene are introduced into a compatible host, generally a Bacillus already overproducing serine protease. Preferred host cells are those from Bacillus novo sp. PB92 and the preferred serine protease gene also originates from Bacillus PB92. Integration and maintenance of the plasmid in the host cell chromosome can be achieved by including a temperature sensitive origin of replication in the plasmid construct and growing under selective conditions.
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3.发明授权DNA constructs containing a Kluyveromyces alpha factor leader sequence for directing secretion of heterologous polypeptides 失效含有用于引导异源多肽分泌的克鲁维酵母属α因子前导序列的DNA构建体
公开(公告)号：US5010182A
公开(公告)日：1991-04-23
申请号：US78551
申请日：1987-07-28
IPC分类号： C07H21/04 , C07K14/39 , C12N9/64 , C12N15/00 , C12N15/09 , C12N15/81 , C12P21/00 , C12P21/02 , C12R1/645
CPC分类号： C12N9/6481 , C07K14/39 , C12N15/815 , C07K2319/00 , C07K2319/02
摘要： DNA constructs that are useful for providing secretory expression of heterologous polypeptides in yeast comprising a DNA sequence that includes a Kluyveromyces .alpha.-factor leader sequence linked to the heterologous polypeptide by a yeast processing signal. Constructs employing the K. lactis .alpha.-factor leader and processing signal sequences, with and without spacer, linked to prochymosin are exemplified.
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公开(公告)号：US4430434A
公开(公告)日：1984-02-07
申请号：US147483
申请日：1980-05-07
IPC分类号： C12N15/09 , C07H21/04 , C12N1/20 , C12N15/75 , C12P19/34 , C12R1/07 , C12R1/085 , C12R1/19 , C12R1/44 , C12R1/445 , C12N1/00 , C12N15/00 , C12P21/00
CPC分类号： C12N15/75
摘要： Plasmid conferring resistance to streptomycin (Sm.sup.R) and neomycin (Neo.sup.R) upon its host (e.g. a Bacillus, Staphylococcus or Escherichia coli) and which after having taken up a foreign DNA fragment at one of its restriction sites with loss of its Sm.sup.R or Neo.sup.R phenotype, is still capable of replicating and expressing genetic information in its host.
摘要翻译： 其质粒赋予其宿主（例如芽孢杆菌属，葡萄球菌属或大肠杆菌）上的链霉素（SmR）和新霉素（NeoR）的抗性，并且在其限制性位点之一吸收了外来DNA片段后失去其SmR或NeoR表型 ，仍然能够在其宿主中复制和表达遗传信息。
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公开(公告)号：US3923981A
公开(公告)日：1975-12-02
申请号：US50186374
申请日：1974-09-11
申请人： GIST BROCADES NV
发明人： VOS CORNELIS , DEN ADMIRANT JACOBUS
CPC分类号： A23K50/30 , A23K20/195
摘要： A new antibiotic being a yellow, salt-forming weak acid, and its non-toxic, pharmaceutically acceptable salts produced by a novel microorganism called Streptomyces ramocissimus, a sample of which is deposited in the collection of ''''Centraal Bureau voor Schimmelcultures'''' at Baarn, The Netherlands, under No. CBS 190.69, or mutants thereof, which antibiotic possesses growthpromoting properties and is especially useful to be added to animal feed although the antibiotic may also be used for therapeutic purposes.
摘要翻译： 一种新的抗生素是一种黄色的盐形成弱酸，以及其无毒的药学上可接受的盐，由称为Streptomyces ramocissimus的新型微生物产生，其样品保藏在Baarn的“Centraal Bureau voor Schimmelcultures” 荷兰，根据CBS 190.69，或其突变体，其抗生素具有生长促进性质，并且特别可用于加入到动物饲料中，尽管抗生素也可用于治疗目的。
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公开(公告)号：US3322651A
公开(公告)日：1967-05-30
申请号：US35242664
申请日：1964-03-12
发明人： NIELSEN EARL A
IPC分类号： C07C37/86
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公开(公告)号：US3188716A
公开(公告)日：1965-06-15
申请号：US15157461
申请日：1961-11-10
申请人： WESTERN ELECTRIC CO
发明人： MCGRAW JR GEORGE P
IPC分类号： H01G13/00
CPC分类号： H01G13/00 , Y10T29/435
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公开(公告)号：US2739173A
公开(公告)日：1956-03-20
申请号：US30553252
申请日：1952-08-21
发明人： COREY ALBERT E , COSBY JOHN N
IPC分类号： C11D19/00
CPC分类号： C11D19/00
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公开(公告)号：US2170094A
公开(公告)日：1939-08-22
申请号：US12251337
申请日：1937-01-27
发明人： FRED RICKS
IPC分类号： D05B15/00
CPC分类号： D05B15/005
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10.发明授权Process for obtaining aroma components and aromas from their precursors of a glycosidic nature, and aroma components and aromas thereby obtained 失效从其糖苷性质的前体获得香气成分和香气的方法，由此获得的香气成分和香气
公开(公告)号：US6106872A
公开(公告)日：2000-08-22
申请号：US062702
申请日：1993-05-14
申请人： Ziya Gunata , Sylvaine Bitteur , Raymond Baumes , Jean-Marc Brillouet , Claude Tapiero , Claude Bayonove , Robert Cordonnier
发明人： Ziya Gunata , Sylvaine Bitteur , Raymond Baumes , Jean-Marc Brillouet , Claude Tapiero , Claude Bayonove , Robert Cordonnier
CPC分类号： C12P7/02
摘要： An enzymatic hydrolysis of a glycosidic substrate containing at least one of the said precursors is performed with at least one enzyme chosen in accordance with the structure of the said precursor, to liberate the corresponding monoglycosides by cleavage at a glycoside bond, and, in a second stage, an enzymatic hydrolysis of the product of the first stage is performed with at least one enzyme other than or identical to that/those of the first stage and designed to liberate the aroma components and aromas by cleavage of the aglycone-carbohydrate linkage bond. A vegetable material derived from a fruit such as grape or an aromatic or flowering plant, as well as their derivatives and by-products, is chosen as a glycosidic substrate. Terepenols such as geraniol, linalol, nerol and the like, terpene polyols and alcohols such as phenyl ethyl alcohol and benzyl alcohol, or the like, are obtained, in particular, as aroma components or aromas.
摘要翻译： 含有至少一种所述前体的糖苷底物的酶水解用至少一种根据所述前体的结构选择的酶进行，以通过在糖苷键处的切割释放相应的单糖苷，并且在第二种 第一阶段的产物的酶水解用至少一种与第一级不同或相同的酶进行，并被设计成通过切断糖苷配基 - 碳水化合物键而释放出芳香成分和香气。 选自衍生自水果如葡萄或芳香或开花植物的植物材料及其衍生物和副产物作为糖苷底物。 尤其是作为芳香成分或芳香，特别是作为香叶醇，香叶醇，橙花醇等的三环酚类，萜烯多元醇，苯基乙醇，苯甲醇等醇类。
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