公开(公告)号：US20190240036A1

公开(公告)日：2019-08-08

申请号：US16268074

申请日：2019-02-05

申请人： ADDITIVE ORTHOPAEDICS, LLC

发明人： Gregory J. KOWALCZYK ,  Brian R. MCLAUGHLIN ,  Selene G. PAREKH ,  Luciano Bernardino BERTOLOTTI

IPC分类号： A61F2/42 ,  A61B17/17 ,  A61F2/46

CPC分类号： A61F2/4202 ,  A61B17/1775 ,  A61F2/4606 ,  A61F2002/30144 ,  A61F2002/30243 ,  A61F2002/3025 ,  A61F2002/30286 ,  A61F2002/30299 ,  A61F2002/30322 ,  A61F2002/30578 ,  A61F2002/30593 ,  A61F2002/30909 ,  A61F2002/30919 ,  A61F2002/3092 ,  A61F2002/4205

摘要： There is disclosed a bone fixation device that can include a cage having an optional mesh portion. The bone fixation device can be configured to couple a leg portion to a foot portion of a user's body. In at least one embodiment, the device includes at least one cage having a plurality of struts forming cells. There can be an optional mesh portion having a pre-set porosity that can be either constant or variable in density. In at least one embodiment there can be a cage portion which is substantially spherical shaped. Alternatively, the device can be substantially egg shaped. In at least one embodiment there can be a central post hole for receiving a post. In another embodiment at least one plate or shaft can connect to the cage.

公开(公告)号：US20180271659A1

公开(公告)日：2018-09-27

申请号：US15542352

申请日：2016-01-07

申请人： Formae, Inc.

发明人： Kevin A. Mansmann ,  Edward J. Cheal

IPC分类号： A61F2/30

CPC分类号： A61F2/30756 ,  A61F2/30749 ,  A61F2/30767 ,  A61F2002/30135 ,  A61F2002/30136 ,  A61F2002/30143 ,  A61F2002/30144 ,  A61F2002/30235 ,  A61F2002/30461 ,  A61F2002/30462 ,  A61F2002/30471 ,  A61F2002/30485 ,  A61F2002/3055 ,  A61F2002/30673 ,  A61F2002/30757 ,  A61F2002/30759 ,  A61F2002/30772 ,  A61F2002/30841 ,  A61F2002/30878 ,  A61F2002/3092 ,  A61F2002/3093 ,  A61F2002/30985

摘要： An prosthetic implant replaces hyaline cartilage in a synovial joint with a flexible polymer sliding surface, preferably of hydrogel, on a segmented support with an array of adjacent segments to which the hydrogel is molded. Adjacent segments are laterally and angularly displaceable permitting the implant to conform to rounded or irregular surfaces or to be rolled or folded for arthroscopic placement. Tension cables threaded through segments along a circuit can cinch segments together for stiffening the supporting layer and/or the cable can pull the implant against a bone surface. Adjacent segments can have inter-engaged structures. In some embodiments the segments are carried on a flexible foil or fibrous sheet.

公开(公告)号：US20180243094A1

公开(公告)日：2018-08-30

申请号：US15903667

申请日：2018-02-23

申请人： HD LifeSciences LLC

发明人： Christopher L. Jones ,  Ian Helmar ,  Lucas Diehl ,  Jason Tinley ,  Kevin D. Chappuis ,  John F. Sullivan

IPC分类号： A61F2/28 ,  A61F2/00 ,  B22F3/105

CPC分类号： A61F2/28 ,  A61F2/0077 ,  A61F2/30767 ,  A61F2/30942 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2/447 ,  A61F2002/0081 ,  A61F2002/30006 ,  A61F2002/30014 ,  A61F2002/30016 ,  A61F2002/30029 ,  A61F2002/30084 ,  A61F2002/30141 ,  A61F2002/30143 ,  A61F2002/30144 ,  A61F2002/30146 ,  A61F2002/30148 ,  A61F2002/30149 ,  A61F2002/30151 ,  A61F2002/30153 ,  A61F2002/30154 ,  A61F2002/30156 ,  A61F2002/30158 ,  A61F2002/30273 ,  A61F2002/3028 ,  A61F2002/30331 ,  A61F2002/30593 ,  A61F2002/30594 ,  A61F2002/30904 ,  A61F2002/30914 ,  A61F2002/3092 ,  A61F2002/3093 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30971 ,  A61F2002/30985 ,  A61F2002/4475 ,  A61F2002/4629 ,  A61L27/06 ,  A61L27/32 ,  A61L27/54 ,  A61L2400/18 ,  B22F3/1055 ,  B22F2005/005 ,  B23K15/0086 ,  B33Y10/00 ,  B33Y50/00 ,  B33Y80/00 ,  Y02P10/295

摘要： The invention disclosed herein includes implant features that can be used, in some embodiments, on devices with a volumetric density of less than about 100 percent and devices with a surface roughness of some value. The implant features include one or more protrusions mounted on the forward edge of an implant that can ease the distraction of tissue during implantation and reduce the occurrence of damage during a manufacturing process. In some embodiments, the protrusions have gaps in a non-axial direction with respect to the implant to allow axial compression with respect to the protrusions. In some embodiments, the protrusions have a circumferential gap between them and a body of a device to reduce any impact on the device's elastic modulus.

公开(公告)号：US20180228613A1

公开(公告)日：2018-08-16

申请号：US15895213

申请日：2018-02-13

申请人： HD LifeSciences LLC

发明人： Christopher L. Jones ,  Ian Helmar ,  Lucas Diehl ,  Jason Tinley ,  Kevin D. Chappuis ,  John F. Sullivan

IPC分类号： A61F2/30 ,  B33Y50/00

CPC分类号： A61F2/30767 ,  A61B90/39 ,  A61B2090/3966 ,  A61F2/30771 ,  A61F2/30942 ,  A61F2/44 ,  A61F2/4455 ,  A61F2002/30029 ,  A61F2002/3008 ,  A61F2002/3009 ,  A61F2002/30141 ,  A61F2002/30144 ,  A61F2002/30146 ,  A61F2002/30148 ,  A61F2002/30151 ,  A61F2002/30153 ,  A61F2002/30154 ,  A61F2002/30171 ,  A61F2002/30263 ,  A61F2002/30273 ,  A61F2002/3028 ,  A61F2002/30331 ,  A61F2002/3092 ,  A61F2002/3093 ,  A61F2002/30945 ,  A61F2002/30952 ,  A61F2002/4495 ,  A61F2250/0098 ,  A61F2310/00011 ,  B33Y50/00

摘要： The biocompatible lattice structures disclosed herein with an increased or optimized lucency are prepared according to multiple methods of design disclosed herein. The methods allow for the design of a metallic material with sufficient strength for use in an implant and that remains radiolucent for x-ray imaging.

公开(公告)号：US08092536B2

公开(公告)日：2012-01-10

申请号：US12203727

申请日：2008-09-03

申请人： Michael Ahrens ,  Erik O. Martz

发明人： Michael Ahrens ,  Erik O. Martz

IPC分类号： A61F2/44

CPC分类号： A61F2/441 ,  A61B17/7094 ,  A61B17/7095 ,  A61B17/7097 ,  A61B17/8811 ,  A61F2002/30004 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30079 ,  A61F2002/3008 ,  A61F2002/30092 ,  A61F2002/30144 ,  A61F2002/30177 ,  A61F2002/302 ,  A61F2002/30224 ,  A61F2002/30242 ,  A61F2002/3025 ,  A61F2002/30252 ,  A61F2002/30261 ,  A61F2002/30273 ,  A61F2002/30289 ,  A61F2002/30471 ,  A61F2002/30565 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30586 ,  A61F2002/30588 ,  A61F2002/30677 ,  A61F2002/30841 ,  A61F2002/30878 ,  A61F2002/4435 ,  A61F2002/444 ,  A61F2002/448 ,  A61F2002/4495 ,  A61F2002/4629 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0085 ,  A61F2210/009 ,  A61F2220/0091 ,  A61F2230/0017 ,  A61F2230/0056 ,  A61F2230/0065 ,  A61F2230/0069 ,  A61F2230/0071 ,  A61F2230/0073 ,  A61F2230/0082 ,  A61F2230/0086 ,  A61F2230/0091 ,  A61F2250/0014 ,  A61F2250/003 ,  A61F2250/0098 ,  A61F2310/00011 ,  A61F2310/00023 ,  A61F2310/00179

摘要： An assembly for the in situ formation of a prosthesis in an intervertebral disc space between adjacent vertebrae of a patient. At least one retention structure is located in the intervertebral disc space. A distal end of at least one lumen is located proximate the at least one retention structure. One or more in situ curable biomaterials are delivered to the intervertebral disc space through the first lumen and into engagement with the retention structure. The retention structure serves to retain at least a portion of the biomaterial in the intervertebral disc space by surface tension, adhesion, mechanical capture, friction, viscosity, and/or a variety of other mechanisms. The at least partially cured biomaterial and the at least one retention structure cooperate to comprise the prosthesis.

摘要翻译： 用于在患者的相邻椎骨之间的椎间盘间隙中原位形成假体的组件。 至少一个保留结构位于椎间盘空间中。 至少一个内腔的远端位于至少一个保持结构附近。 一个或多个原位可固化生物材料通过第一内腔被输送到椎间盘空间并与保留结构接合。 保持结构用于通过表面张力，粘附力，机械捕获，摩擦，粘度和/或各种其它机制将至少一部分生物材料保留在椎间盘空间中。 所述至少部分固化的生物材料和所述至少一个保留结构配合以构成所述假体。

公开(公告)号：US20080306607A1

公开(公告)日：2008-12-11

申请号：US12191541

申请日：2008-08-14

申请人： Yasuharu Hakamatsuka ,  Yuji Takamiya ,  Katsuya Sadamori

发明人： Yasuharu Hakamatsuka ,  Yuji Takamiya ,  Katsuya Sadamori

IPC分类号： A61F2/28

CPC分类号： A61L27/12 ,  A61F2/28 ,  A61F2/30771 ,  A61F2/32 ,  A61F2002/2817 ,  A61F2002/30062 ,  A61F2002/30118 ,  A61F2002/30144 ,  A61F2002/30146 ,  A61F2002/30154 ,  A61F2002/3024 ,  A61F2002/3028 ,  A61F2002/30677 ,  A61F2002/30785 ,  A61F2002/30828 ,  A61F2002/30879 ,  A61F2002/30892 ,  A61F2002/30957 ,  A61F2002/3412 ,  A61F2002/3611 ,  A61F2210/0004 ,  A61F2230/0006 ,  A61F2230/0017 ,  A61F2230/0021 ,  A61F2230/0063 ,  A61F2230/0069 ,  A61F2310/00293

摘要： A bone substitute (a material for repairing biological tissues) made from β-TCP as the raw material comprises a plate-type base member on the surface of which a plurality of grooves extending in a single direction are formed and separated from each other by partition wall members having an almost uniform thickness. This material sustains a sufficient binding force after application to a biological tissue and exhibits an excellent effect of forming a biological tissue. This bone substitute (material for repairing biological tissues) having a main body provided with a plurality of grooves extending in a single direction which are separated from each other by partition wall members having an almost uniform thickness, and a biodegradable viscous member which is filled into at least one of the penetrating holes of the main body, and contains an agonistic factor capable of increasing the cell activity, can provide agonistic factors of sufficient types and amounts to a biological tissue, and can control the sustained-release dose thereof.

摘要翻译： 由β-TCP制成的骨替代物（用于修复生物组织的材料）作为原料，包括板状基材，其表面上形成有沿单个方向延伸的多个槽，并通过分隔彼此分离 壁构件具有几乎均匀的厚度。 这种材料在施用到生物组织后维持足够的结合力，并且表现出优异的形成生物组织的效果。 这种骨替代物（用于修复生物组织的材料）具有主体，该主体设置有沿单个方向延伸的多个槽，所述多个槽通过具有几乎均匀厚度的分隔壁构件彼此分离，以及可生物降解的粘性构件，其被填充 主体的穿透孔中的至少一个，并且含有能够增加细胞活性的激动因子，可以向生物组织提供足够类型和量的激动因子，并且可以控制其持续释放剂量。

公开(公告)号：US20070112434A1

公开(公告)日：2007-05-17

申请号：US10555243

申请日：2004-03-31

申请人： Yasuharu Hakamatsuka ,  Yuji Takamiya ,  Katsuya Sadamori

发明人： Yasuharu Hakamatsuka ,  Yuji Takamiya ,  Katsuya Sadamori

IPC分类号： A61F2/28

CPC分类号： A61L27/12 ,  A61F2/28 ,  A61F2/30771 ,  A61F2/32 ,  A61F2002/2817 ,  A61F2002/30062 ,  A61F2002/30118 ,  A61F2002/30144 ,  A61F2002/30146 ,  A61F2002/30154 ,  A61F2002/3024 ,  A61F2002/3028 ,  A61F2002/30677 ,  A61F2002/30785 ,  A61F2002/30828 ,  A61F2002/30879 ,  A61F2002/30892 ,  A61F2002/30957 ,  A61F2002/3412 ,  A61F2002/3611 ,  A61F2210/0004 ,  A61F2230/0006 ,  A61F2230/0017 ,  A61F2230/0021 ,  A61F2230/0063 ,  A61F2230/0069 ,  A61F2310/00293

摘要： A bone substitute (a material for repairing biological tissues) made from β-TCP as the raw material comprises a plate-type base member on the surface of which a plurality of grooves extending in a single direction are formed and separated from each other by partition wall members having an almost uniform thickness. This material sustains a sufficient binding force after application to a biological tissue and exhibits an excellent effect of forming a biological tissue. This bone substitute (material for repairing biological tissues) having a main body provided with a plurality of grooves extending in a single direction which are separated from each other by partition wall members having an almost uniform thickness, and a biodegradable viscous member which is filled into at least one of the penetrating holes of the main body, and contains an agonistic factor capable of increasing the cell activity, can provide agonistic factors of sufficient types and amounts to a biological tissue, and can control the sustained-release dose thereof.

摘要翻译： 由β-TCP制成的骨替代物（用于修复生物组织的材料）作为原料，包括板状基材，其表面上形成有沿单个方向延伸的多个槽，并通过分隔彼此分离 壁构件具有几乎均匀的厚度。 这种材料在施用到生物组织后维持足够的结合力，并且表现出优异的形成生物组织的效果。 这种骨替代物（用于修复生物组织的材料）具有主体，该主体设置有沿单个方向延伸的多个槽，所述多个槽通过具有几乎均匀厚度的分隔壁构件彼此分离，以及可生物降解的粘性构件，其被填充 主体的穿透孔中的至少一个，并且含有能够增加细胞活性的激动因子，可以向生物组织提供足够类型和量的激动因子，并且可以控制其持续释放剂量。

公开(公告)号：US20050278027A1

公开(公告)日：2005-12-15

申请号：US11150798

申请日：2005-06-10

申请人： Edward Hyde

发明人： Edward Hyde

IPC分类号： A61F2/00 ,  A61F2/02 ,  A61F2/30 ,  A61F2/44 ,  A61F2/46

CPC分类号： A61F2/442 ,  A61F2/30744 ,  A61F2/441 ,  A61F2002/30004 ,  A61F2002/30062 ,  A61F2002/30079 ,  A61F2002/30092 ,  A61F2002/30144 ,  A61F2002/30171 ,  A61F2002/302 ,  A61F2002/3025 ,  A61F2002/30291 ,  A61F2002/30331 ,  A61F2002/30563 ,  A61F2002/30566 ,  A61F2002/30579 ,  A61F2002/30583 ,  A61F2002/30584 ,  A61F2002/30604 ,  A61F2002/30677 ,  A61F2002/30785 ,  A61F2002/30787 ,  A61F2002/30841 ,  A61F2002/30971 ,  A61F2002/4415 ,  A61F2002/4435 ,  A61F2002/4475 ,  A61F2002/4631 ,  A61F2210/0004 ,  A61F2210/0014 ,  A61F2210/0085 ,  A61F2210/009 ,  A61F2220/0033 ,  A61F2230/0017 ,  A61F2230/005 ,  A61F2230/0065 ,  A61F2230/0071 ,  A61F2230/0091 ,  A61F2250/0014 ,  A61F2310/00017 ,  A61F2310/00023 ,  A61F2310/00161 ,  A61F2310/00293 ,  A61F2310/00796

摘要： The Annulus Fibrosus Stent (AFS) is a platform of barriers used in the intervertebral disc. The barrier can be inserted into an intervertebral disc to act to reinforce and/or supplement the disc. The AFS can be inserted at any of the many different stages of disc pathology. The AFS can be inserted to prevent pressure and dissection of disc material which in and of itself can decrease and/or eliminate pain from damaged AF fibers. The AFS can be inserted before disc pathology progresses to a substantial event such as a disc herniation. It can be inserted at any time in the progression of the natural history of disc disease. It can even be inserted when substantially the entire intervertebral disc has been removed. It can be inserted in conjunction with another procedure such as a Nucleus Pulposus Replacement (NPR) or Total Disc Replacement (TDR), etc. The various shapes and material of the AFS in this patent are designed to address particular clinical situations, particular anatomy and particular stages of disc degeneration. The AFS can be inserted directly through the AF, or by a technique of detaching part of the AF with bone without actually cutting a substantial part of AF fibers or layers of fibers or by the Transosseous approach.

摘要翻译： 环形纤维支架（AFS）是椎间盘中使用的障碍平台。 障碍物可以插入到椎间盘中以用于加强和/或补充椎间盘。 AFS可以插入椎间盘病理学的许多不同阶段的任何一个。 可以插入AFS以防止椎间盘材料的压力和解剖，其本身可以减少和/或消除损伤的AF纤维的疼痛。 在椎间盘病变发展到椎间盘突出症等重大事件之前，可以插入AFS。 随时可以插入椎间盘疾病的自然病史。 当基本上整个椎间盘已经被移除时，甚至可以插入它。 它可以与另一个过程（例如，髓核替代（NPR）或总盘替代（TDR）等）一起插入。本专利中的AFS的各种形状和材料被设计为解决特定的临床情况，特定解剖结构和 椎间盘退变的特定阶段。 AFS可以通过AF直接插入，也可以通过用骨头分离部分AF的技术，而不会实际切割大部分AF纤维或纤维层，或通过Transosseous方法。

公开(公告)号：US09814595B2

公开(公告)日：2017-11-14

申请号：US15012827

申请日：2016-02-01

申请人： Biedermann Technologies GmbH & Co. KG

发明人： Lutz Biedermann ,  Wilfried Matthis ,  Helmar Rapp

IPC分类号： A61F2/44 ,  G02F1/1343 ,  G02F1/1345 ,  A61B17/70 ,  A61B17/72 ,  A61B17/80 ,  A61F2/30 ,  A61F2/28 ,  H01L29/45 ,  H01L29/49 ,  H01L27/12

CPC分类号： A61F2/442 ,  A61B17/7001 ,  A61B17/72 ,  A61B17/80 ,  A61F2/30767 ,  A61F2/44 ,  A61F2/4455 ,  A61F2/4465 ,  A61F2002/2825 ,  A61F2002/30115 ,  A61F2002/30126 ,  A61F2002/30131 ,  A61F2002/30133 ,  A61F2002/30144 ,  A61F2002/30146 ,  A61F2002/30148 ,  A61F2002/30153 ,  A61F2002/30154 ,  A61F2002/30156 ,  A61F2002/30235 ,  A61F2002/3024 ,  A61F2002/30441 ,  A61F2002/30451 ,  A61F2002/30485 ,  A61F2002/30492 ,  A61F2002/30507 ,  A61F2002/3055 ,  A61F2002/30551 ,  A61F2002/30601 ,  A61F2002/30672 ,  A61F2002/30787 ,  A61F2002/30841 ,  A61F2002/30912 ,  A61F2002/3097 ,  A61F2002/4475 ,  A61F2220/0025 ,  A61F2220/0041 ,  A61F2220/0058 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/0013 ,  A61F2230/0015 ,  A61F2230/0017 ,  A61F2230/0019 ,  A61F2230/0021 ,  A61F2230/0023 ,  A61F2230/0069 ,  A61F2310/00023 ,  A61F2310/00796 ,  G02F1/13439 ,  G02F1/13458 ,  H01L27/12 ,  H01L27/124 ,  H01L29/458 ,  H01L29/4908

摘要： A placeholder for vertebrae or vertebral discs includes a tubular body, which along its jacket surface has a plurality of breakthroughs or openings for over-growth with adjacent tissue. The placeholder includes at least a second tubular body provided with a plurality of breakthroughs and openings at least partially inside the first tubular body. The first and second tubular bodies can have different cross-sectional shapes, can be are arranged inside one another by press fit or force fit or can be connected to each other via connecting pins and arranged side by side to one another in the first body.

公开(公告)号：US20150066152A1

公开(公告)日：2015-03-05

申请号：US14017178

申请日：2013-09-03

申请人： Massachusetts Institute of Technology

发明人： Alexander H. Slocum, JR. ,  Adam T. Paxson ,  Jonathan David Smith ,  Daniel H. Goodman ,  Kripa K. Varanasi

IPC分类号： A61F2/30

CPC分类号： A61F2/30767 ,  A61F2/30771 ,  A61F2002/30144 ,  A61F2002/30673 ,  A61F2002/30838 ,  A61F2002/3084

摘要： The present disclosure provides, among other things, prosthetic joint components having textured surface(s) for improving lubrication and increasing the useful life of the prosthetic joint components. The textured surface includes solid features configured to stably contain a biological fluid or a synthetic biological fluid therebetween or therewithin for a non-zero residence time.

摘要翻译： 本公开尤其提供具有用于改善润滑并且增加假体关节部件的使用寿命的具有纹理表面的修复关节部件。 纹理表面包括固体特征，其被配置为在其间或其内部稳定地容纳生物流体或合成生物流体以达到非零停留时间。