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    Method for solid-phase microextraction and analysis, and a collector for this method
    2.
    发明授权
    Method for solid-phase microextraction and analysis, and a collector for this method 有权
    固相微萃取和分析方法，以及该方法的收集器

    公开(公告)号：US06815216B2

    公开(公告)日：2004-11-09

    申请号：US09967333

    申请日：2001-09-27

    申请人： Patrick Sandra ,  Erik Baltussen ,  Frank David

    发明人： Patrick Sandra ,  Erik Baltussen ,  Frank David

    IPC分类号： G01N118

    CPC分类号： G01N1/34 ,  G01N1/405 ,  G01N30/12 ,  G01N2030/009 ,  G01N2030/062 ,  G01N2030/121 ,  G01N2030/128 ,  Y10T436/156666 ,  Y10T436/25 ,  Y10T436/25125 ,  Y10T436/2525 ,  Y10T436/25375 ,  Y10T436/255 ,  Y10T436/25875 ,  B01D2015/389

    摘要： The invention relates to a method for solid-phase microextraction and analysis of substances in a carrier fluid, in which a collector is brought into contact with the stirred fluid containing the substances for a sufficient time and is then subjected to a solid-phase extraction directed at at least one substance adhering to the collector, and desorbed substances are transported for analysis by means of a carrier gas, in which the carrier fluid containing the substances is stirred in a receptacle of a magnetic stirrer by means of a coated magnetic stirring element as the collector, and/or the carrier fluid is made to move intimately relative to the collector by means of ultrasound, and then the stirring element is placed in a solid-phase extraction device.

    摘要翻译： 本发明涉及一种用于固相微萃取和分析载体流体中的物质的方法，其中集流体与含有物质的搅拌流体接触足够的时间，然后进行固相萃取 在附着在集电体上的至少一种物质，并且解吸物质通过载气进行分析，所述载体气体通过涂覆的磁力搅拌元件将含有物质的载体流体在磁力搅拌器的容器中搅拌， 收集器和/或载体流体通过超声使其相对于收集器紧密地移动，然后将搅拌元件置于固相萃取装置中。

    Focused acoustic ejection cell sorting system and method
    3.
    发明申请
    Focused acoustic ejection cell sorting system and method 有权
    聚焦声弹出细胞分选系统及方法

    公开(公告)号：US20050130257A1

    公开(公告)日：2005-06-16

    申请号：US11049206

    申请日：2005-02-01

    申请人： Mitchell Mutz ,  Richard Ellson ,  David Lee

    发明人： Mitchell Mutz ,  Richard Ellson ,  David Lee

    IPC分类号： B41J2/14 ,  C12M1/26 ,  C12M3/00 ,  C12N5/02 ,  G01N15/10 ,  G01N15/14 ,  G01N30/02 ,  C12P33/02 ,  B07C5/02

    CPC分类号： G01N35/1074 ,  B41J2/14008 ,  C12M47/04 ,  G01N15/1056 ,  G01N29/0681 ,  G01N30/02 ,  G01N2015/1081 ,  G01N2015/1415 ,  G01N2015/142 ,  G01N2035/1039 ,  B01D2015/389

    摘要： A method is provided for acoustically ejecting from a channel or other container a plurality of fluid droplets, each of which contains one or more particles or other localized volumes. The localized volumes, which can be living cells, are ejected towards sites on a substrate surface, a container, or a channel. An integrated cell sorting and arraying system is also provided that is capable of sorting based upon cellular properties by the selective ejection of cells from a carrier fluid. The cells can be ejected with adjustable velocity and trajectory. The ejected cells can be directed to form an array, wherein each site of the array can contain a single cell. Additionally provided is a method of forming arrays of single live cells more efficiently, rapidly, flexibly, and economically than by other cell array approaches. This method permits efficient, continuous, and simultaneous sorting of cells based upon the quantitative or semiquantitative measurement of cellular properties, and also permits non-binary or severally-branched decision-making. An integrated system, which includes a processor, and methods are also provided for the detection, selection, and ejection of selected particles or circumscribed volumes, such as live cells, from a continuous stream of fluid-suspended particles or other circumscribed volumes flowing in channels.

    摘要翻译： 提供了一种用于从通道或其它容器声学喷射多个流体液滴的液滴，每个流体液滴包含一个或多个颗粒或其它局部体积。 可以是活细胞的局部体积被排出到基底表面，容器或通道上的位置。 还提供了一种综合的细胞分选和排列系统，其能够通过从载体液体中选择性地排出细胞而基于细胞特性进行分选。 可以以可调节的速度和轨迹弹出细胞。 排出的细胞可以被引导以形成阵列，其中阵列的每个位点可以包含单个细胞。 另外提供了一种形成单个活细胞阵列的方法，其比单体阵列方法更有效，快速，灵活和经济地形成。 该方法允许基于细胞性质的定量或半定量测量来对细胞进行有效，连续和同时的分选，并且还允许非二元或分支分支的决策。 还提供了一种包括处理器和方法的集成系统，用于从流体悬浮颗粒的连续流或在通道中流动的其它外接体积检测，选择和排出所选择的颗粒或外切体积（例如活细胞） 。

    Device for the rapid separation and/or conversion of substrates
    6.
    发明授权
    Device for the rapid separation and/or conversion of substrates 有权
    用于快速分离和/或转换基材的装置

    公开(公告)号：US06319401B1

    公开(公告)日：2001-11-20

    申请号：US09276711

    申请日：1999-03-26

    申请人： Djuro Josic ,  Primoz Koselj ,  Ales Podgronik ,  Ales Strancar

    发明人： Djuro Josic ,  Primoz Koselj ,  Ales Podgronik ,  Ales Strancar

    IPC分类号： B01D6500

    CPC分类号： B01J20/3242 ,  B01D15/1821 ,  B01D15/1892 ,  B01D15/22 ,  B01J20/28014 ,  B01J20/28042 ,  G01N30/02 ,  G01N30/6017 ,  G01N30/6069 ,  G01N2030/324 ,  G01N2030/386 ,  G01N2030/527 ,  B01D2015/389

    摘要： A device for the rapid separation and/or conversion of substrates is disclosed herein. The device include a porous tube (2) disposed inside a tubular sample distributor (3). The tubular sample distributor (3) includes channel structures on its inner surface and is disposed inside a tubular body (4). A tubular sample collector (1) having channel structures on its outer surface is disposed inside the porous tube (2). A circular sample distributor (7) is provided having a circumferential portion and radially extending grooves in conjunction with the channel structures of the tubular sample distributor (3). A circular sample collector (8) is also provided having a circumferential portion and radially extending grooves in conjunction with the channel structures of the tubular sample collector (1). The hollow body (4) is arranged between securing means (5) that provide a sample inlet and outlet in communication with the circular sample distributor (7) and circular sample collector (8), respectively.

    摘要翻译： 本文公开了用于快速分离和/或转换基底的装置。 该装置包括设置在管状样品分配器（3）内的多孔管（2）。 管状样品分配器（3）在其内表面上包括通道结构，并且设置在管状体（4）的内部。 在其外表面上具有通道结构的管状样品收集器（1）设置在多孔管（2）的内部。 圆形样品分配器（7）设置有与管状样品分配器（3）的通道结构相结合的周向部分和径向延伸的凹槽。 还提供了圆形样品收集器（8），其具有与管状样品收集器（1）的通道结构相结合的圆周部分和径向延伸的凹槽。 中空体（4）分别设置在提供与圆形样品分配器（7）和圆形样品收集器（8）连通的样品入口和出口的固定装置（5）之间。

    Method for solid-phase microextraction and analysis, and a collector for this method
    9.
    发明申请
    Method for solid-phase microextraction and analysis, and a collector for this method 有权
    固相微萃取和分析方法，以及该方法的收集器

    公开(公告)号：US20020098594A1

    公开(公告)日：2002-07-25

    申请号：US09967333

    申请日：2001-09-27

    申请人： Gerstel Systemtechnik GmbH & Co. KG

    发明人： Patrick Sandra ,  Erik Baltussen ,  Frank David

    IPC分类号： G01N001/00

    CPC分类号： G01N1/34 ,  G01N1/405 ,  G01N30/12 ,  G01N2030/009 ,  G01N2030/062 ,  G01N2030/121 ,  G01N2030/128 ,  Y10T436/156666 ,  Y10T436/25 ,  Y10T436/25125 ,  Y10T436/2525 ,  Y10T436/25375 ,  Y10T436/255 ,  Y10T436/25875 ,  B01D2015/389

    摘要： The invention relates to a method for solid-phase microextraction and analysis of substances in a carrier fluid, in which a collector is brought into contact with the stirred fluid containing the substances for a sufficient time and is then subjected to a solid-phase extraction directed at at least one substance adhering to the collector, and desorbed substances are transported for analysis by means of a carrier gas, in which the carrier fluid containing the substances is stirred in a receptacle of a magnetic stirrer by means of a coated magnetic stirring element as the collector, and/or the carrier fluid is made to move intimately relative to the collector by means of ultrasound, and then the stirring element is placed in a solid-phase extraction device.

    摘要翻译： 本发明涉及一种用于固相微萃取和分析载体流体中的物质的方法，其中集流体与含有物质的搅拌流体接触足够的时间，然后进行固相萃取 在附着在集电体上的至少一种物质，并且解吸物质通过载气进行分析，所述载体气体通过涂覆的磁力搅拌元件将含有物质的载体流体在磁力搅拌器的容器中搅拌， 收集器和/或载体流体通过超声使其相对于收集器紧密地移动，然后将搅拌元件置于固相萃取装置中。